JP2020517652A5 - - Google Patents

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JP2020517652A5
JP2020517652A5 JP2019556986A JP2019556986A JP2020517652A5 JP 2020517652 A5 JP2020517652 A5 JP 2020517652A5 JP 2019556986 A JP2019556986 A JP 2019556986A JP 2019556986 A JP2019556986 A JP 2019556986A JP 2020517652 A5 JP2020517652 A5 JP 2020517652A5
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JP
Japan
Prior art keywords
axl
cancer
antibody
adc
cells
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JP2019556986A
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English (en)
Japanese (ja)
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JP2020517652A (ja
JP7408396B2 (ja
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Priority claimed from GBGB1706225.8A external-priority patent/GB201706225D0/en
Priority claimed from GBGB1706224.1A external-priority patent/GB201706224D0/en
Priority claimed from GBGB1706227.4A external-priority patent/GB201706227D0/en
Priority claimed from GBGB1706226.6A external-priority patent/GB201706226D0/en
Priority claimed from GBGB1706228.2A external-priority patent/GB201706228D0/en
Priority claimed from GBGB1706223.3A external-priority patent/GB201706223D0/en
Priority claimed from GBGB1706230.8A external-priority patent/GB201706230D0/en
Priority claimed from GBGB1706231.6A external-priority patent/GB201706231D0/en
Priority claimed from GBGB1706229.0A external-priority patent/GB201706229D0/en
Application filed filed Critical
Priority claimed from PCT/EP2018/060209 external-priority patent/WO2018193102A1/en
Publication of JP2020517652A publication Critical patent/JP2020517652A/ja
Publication of JP2020517652A5 publication Critical patent/JP2020517652A5/ja
Application granted granted Critical
Publication of JP7408396B2 publication Critical patent/JP7408396B2/ja
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JP2019556986A 2017-04-20 2018-04-20 併用療法 Active JP7408396B2 (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
GB1706230.8 2017-04-20
GB1706224.1 2017-04-20
GB1706226.6 2017-04-20
GB1706228.2 2017-04-20
GBGB1706223.3A GB201706223D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706230.8A GB201706230D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706231.6A GB201706231D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706227.4 2017-04-20
GB1706223.3 2017-04-20
GBGB1706228.2A GB201706228D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706224.1A GB201706224D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706229.0 2017-04-20
GBGB1706229.0A GB201706229D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706226.6A GB201706226D0 (en) 2017-04-20 2017-04-20 Combination therapy
GB1706225.8 2017-04-20
GB1706231.6 2017-04-20
GBGB1706225.8A GB201706225D0 (en) 2017-04-20 2017-04-20 Combination therapy
GBGB1706227.4A GB201706227D0 (en) 2017-04-20 2017-04-20 Combination therapy
PCT/EP2018/060209 WO2018193102A1 (en) 2017-04-20 2018-04-20 Combination therapy with an anti-axl antibody-drug conjugate

Publications (3)

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JP2020517652A JP2020517652A (ja) 2020-06-18
JP2020517652A5 true JP2020517652A5 (cg-RX-API-DMAC7.html) 2021-05-27
JP7408396B2 JP7408396B2 (ja) 2024-01-05

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JP2019556986A Active JP7408396B2 (ja) 2017-04-20 2018-04-20 併用療法

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US (2) US20200129637A1 (cg-RX-API-DMAC7.html)
EP (1) EP3612234B1 (cg-RX-API-DMAC7.html)
JP (1) JP7408396B2 (cg-RX-API-DMAC7.html)
KR (1) KR20190141666A (cg-RX-API-DMAC7.html)
CN (1) CN110536703B (cg-RX-API-DMAC7.html)
AU (1) AU2018253948B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019021880A2 (cg-RX-API-DMAC7.html)
CA (1) CA3057748A1 (cg-RX-API-DMAC7.html)
ES (1) ES2977788T3 (cg-RX-API-DMAC7.html)
MX (1) MX2019012464A (cg-RX-API-DMAC7.html)
NZ (1) NZ756730A (cg-RX-API-DMAC7.html)
PL (1) PL3612234T3 (cg-RX-API-DMAC7.html)
WO (1) WO2018193102A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201905727B (cg-RX-API-DMAC7.html)

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GB201908128D0 (en) 2019-06-07 2019-07-24 Adc Therapeutics Sa Pyrrolobenzodiazepine-antibody conjugates
WO2021013746A1 (en) * 2019-07-19 2021-01-28 Genmab A/S Axl antibody-drug conjugates for use in treating cancer
GB202006072D0 (en) * 2020-04-24 2020-06-10 Bergenbio Asa Method of selecting patients for treatment with cmbination therapy
GB202011993D0 (en) 2020-07-31 2020-09-16 Adc Therapeutics Sa ANTI-IL 13Ra2 antibodies
NL2026947B1 (en) * 2020-11-20 2022-07-01 Synaffix Bv Tyrosine-based antibody conjugates
WO2022197933A1 (en) 2021-03-18 2022-09-22 The Broad Institute, Inc. Compositions and methods for characterizing lymphoma and related conditions
WO2022261846A1 (zh) * 2021-06-16 2022-12-22 上海鑫湾生物科技有限公司 靶向axl蛋白的抗体及其抗原结合片段、其制备方法和应用
CN113662943A (zh) * 2021-08-04 2021-11-19 深圳湾实验室 酪氨酸激酶axl抑制剂预防或治疗冠状病毒感染的用途
WO2023129667A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3
IL289525B2 (en) * 2021-12-30 2023-03-01 B G Negev Technologies And Applications Ltd At Ben Gurion Univ Conjugated antibodies for cancer treatment
EP4389152A1 (en) * 2022-12-23 2024-06-26 Synaffix B.V. Conjugates of pbd prodrugs
WO2025063789A1 (ko) * 2023-09-21 2025-03-27 주식회사 피노바이오 운반체-약물 접합체 및 dnmt-1 저해제의 병용 요법
WO2025113646A1 (zh) * 2023-11-30 2025-06-05 江苏康宁杰瑞生物制药有限公司 包含pd-l1结合分子与双特异性抗体-药物偶联物的组合物及其用途

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