JP2019532688A - 注射器アセンブリ - Google Patents

注射器アセンブリ Download PDF

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JP2019532688A
JP2019532688A JP2019510626A JP2019510626A JP2019532688A JP 2019532688 A JP2019532688 A JP 2019532688A JP 2019510626 A JP2019510626 A JP 2019510626A JP 2019510626 A JP2019510626 A JP 2019510626A JP 2019532688 A JP2019532688 A JP 2019532688A
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syringe
vial
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デネンバーグ，イゴール
ダビデ，ウリ
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ウエスト・ファーマ．サービシーズ・イスラエル，リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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    • A61M39/22—Valves or arrangement of valves
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
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    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
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    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
    • A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M2005/3201—Coaxially assembled needle cannulas placed on top of another, e.g. needles having different diameters
    • A—HUMAN NECESSITIES
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    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs

Abstract

注射器アセンブリは、液剤内容物の投与を可能にするための一体型液剤投与デバイスを予め有する注射器と、液剤内容物を収容する薬瓶に入れ子式に取り付けるための薬瓶アダプタと、を備える。薬瓶アダプタは、注射器に最初に取り付けられ、また、そこから手動で取り外されて、一体型液剤投与デバイスを露出させることが意図されている。注射器は、薬瓶からの液剤内容物で注射器を充填する初期流路位置と、液剤内容物の投与を可能にするための最終流路位置と、を有する流れ制御部材を備える。薬瓶アダプタを注射器から取り外すことによって、流れ制御部材がその初期流路位置から最終流路位置まで押圧される。【選択図】図１

Description

本発明は、注射器アセンブリに関する。
即座に投与する準備ができた液剤用量を収容する予備充填注射器は、約１ｃｍの深さに至る筋肉注射のための一体型の標準筋肉ニードル、または、約２〜３ｍｍの深さに至る皮内注射のための皮内マイクロニードルを備え得る。あるいは、予備充填注射器は、標準的なルアーコネクタニードルハブの取り付けを防止するとともに液剤用量の経口投与を対象とする注射器拡大遠位先端を有し得る。予備充填されたニードルを備える注射器は、あるワクチンでは多量のワクチンの廃棄につながり得るワクチン用量に相当する０．０３ｍｌ〜０．０５ｍｌの標準的なルアーコネクタの死容積よりも非常に小さい死容積を有する。
予備充填注射器は、当該注射器を製造するための製造工程の一部として、液剤用量で充填される。一体型ニードルまたは拡大注射器遠位先端を有する注射器は、使用前に臨床医師によって液剤用量で充填され得るが、そのような手動での充填工程は、概して、時間が掛かるとともに問題があると考えられる。国際公開ＷＯ２０１４／１７４２７８として公開された注射器との標題の国際特許出願ＰＣＴ／ＧＢ２０１４／０５１２５６は、液剤用量を収容する薬瓶からの液剤用量で最初は空の注射器を充填することを補助するための注射器アセンブリを開示している。
使用直前に液剤内容物を容易に充填できる一体型液剤投与デバイスを有する注射器を備える注射器アセンブリが求められる。
本発明は、一体型液剤投与デバイスと薬瓶アダプタとが事前に備えられた注射器を備える注射器アセンブリを対象としている。一体型液剤投与デバイスは、標準的な筋肉ニードル、標準的な皮内マイクロニードル、注射器拡大遠位先端などであってもよい。薬瓶アダプタは、最初に注射器に取り付けられ、液剤内容物の投与を可能にするために、そこから手動で取り外されて一体型液剤投与デバイスを露出させることが意図されている。注射器は、薬瓶からの液剤内容物で注射器を手動で充填することを可能にするための初期流路位置と、液剤内容物を手動で投与することを可能にするための最終流路位置と、を有する流れ制御部材を備えている。薬瓶アダプタを注射器から取り外すことによって、流れ制御部材が、その初期流路位置から、その最終流路位置まで押圧される。注射器からの薬瓶アダプタの取り外しは、手動回転、または、注射器に対する薬瓶アダプタの直線的な取り外しのいずれかによるものであってもよい。
本発明の注射器アセンブリは、好ましくは、空の注射器を有して提供される。注射器アセンブリは、空の注射器に即座に吸引する用意ができた液剤内容物を収容する薬瓶とともに使用され得る。粉末状薬剤を収容する薬瓶の場合、注射器アセンブリは、好ましくは、さらに、粉末状薬剤と混合するための液体内容物を収容する液瓶に入れ子式に取り付けるための液瓶アダプタを備えていてもよい。液体内容物は、復元するためだけの希釈剤であってもよいし、あるいは、活性成分を含んでいてもよい。そのような注射器アセンブリは、次の３つの液体移送のために、その初期流路位置を採用する。１つ目は、液瓶から空の注射器へ液体内容物を吸引するための第１の液体移送である。液瓶アダプタ、および、その空の液瓶は、粉末状薬剤を収容する薬瓶に入れ子式に取り付けることを可能にするために、第１の液剤移送の後に注射器アセンブリから必ず取り外される。２つ目は、液剤内容物を形成するために注射器から薬瓶への液体内容物の注入のための第２の液体移送である。そして、３つ目は、薬瓶から空の注射器へ液剤内容物を吸引するための第３の液体移送である。
本発明を理解し、それが実際にどのように実施され得るのかを理解するために、次に、好ましい実施形態について、同様の部分に同様の番号を付した添付図面を参照して、単なる非限定的な例として説明する。
液剤内容物を収容する薬瓶とともに使用するための初期セットアップ位置にある注射器アセンブリの斜視図である。 液剤内容物を投与する用意ができた注射器アセンブリの斜視図である。 注射器アセンブリの分解図である。 図１の線Ａ−Ａに沿った注射器アセンブリの縦断面図、および、円で囲まれた領域Ａの拡大図である。 図２の線Ｂ−Ｂに沿った注射器アセンブリの縦断面図、および、円で囲まれた領域Ｂの拡大図である。 液剤内容物を投与するための注射器アセンブリの使用方法を示している。 液剤内容物を投与するための注射器アセンブリの使用方法を示している。 液剤内容物を投与するための注射器アセンブリの使用方法を示している。 液剤内容物の経口投与のための注射器拡大遠位先端の斜視図、および、円で囲まれた領域Ｃの拡大図である。 代替的な注射器アセンブリの分解図である。 図８の注射器アセンブリの流れ制御部材の後方斜視図である。 初期流路位置においてその流れ制御部材を有する図８の注射器アセンブリの縦断面図、および、円で囲まれた領域Ｄの拡大図である。 最終流路位置においてその流れ制御部材を有する図８の注射器アセンブリの縦断面図、および、円で囲まれた領域Ｅの拡大図である。 粉末状薬剤を収容する薬瓶と、液体内容物を収容する液瓶と、ともに使用するために修正された図８の注射器アセンブリの縦断面図である。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。 液剤内容物を復元して投与するための図１２の注射器アセンブリの使用方法を示している。
図１〜５は、薬瓶１０とともに使用するための注射器アセンブリ１００Ａを示している。薬瓶１０は、長手方向薬瓶中央線１１を有しており、また、薬瓶チューブ１２と、薬瓶クラウン開口１４を有するチューブ状の薬瓶クラウン１３と、薬瓶チューブ１２と薬瓶クラウン１３との間の小径薬瓶ネック１６と、を備えている。薬瓶１０は、薬瓶チューブ１２と薬瓶ネック１６との間に薬瓶ショルダ１７を備えている。薬瓶１０は、薬瓶クラウン開口１４を塞ぐための薬瓶ストッパ１８を備えている。薬瓶１０は、液剤内容物１９を収容する。薬瓶１０は液剤内容物で予備充填され、あるいは、液剤内容物は、注射器アセンブリ１００Ａとともに使用する前に、その中で復元される。
注射器アセンブリ１００Ａは、長手方向注射器アセンブリ中央線１０１を有しており、また、注射器近位端１０３と注射器遠位先端１０４とを有する注射器１０２と、薬瓶アダプタ１０６と、を備えている。注射器１０２は、注射器バレル近位端１０７Ａと注射器バレル遠位端１０７Ｂと注射器バレル内部１０８とを有する開放端注射器バレル１０７を備えている。注射器１０２は、親指ストッパ１１１を有するプランジャ１０９を備えている。注射器近位端１０３は、フィンガーグリップ１１２の直径対を有している。注射器遠位先端１０４は、長手方向注射器アセンブリ中央線１０１に交差する方向の環状フランジ１１３を有して形成されている。環状フランジ１１３は、雄ネジ１１４を有して形成される。注射器遠位先端１０４は、注射器バレル遠位端１０７Ｂと、注射器近位端１０３Ａに対して環状フランジ１１３の遠位側に形成された開口１１７と、の間を延在する交差方向に向けられた内腔１１６を有して形成される。
注射器遠位先端１０４は、長手方向注射器アセンブリ中央線１０１と同軸の液剤投薬内腔１１９を有している。液剤投薬内腔１１９は、標準的な皮内ニードルによって構成される一体型液剤投与デバイス１２１に適合される。注射器遠位先端１０４は、注射器バレル遠位端１０７Ｂから皮内ニードル１２１に向けてテーパ状に形成された注射器先端円錐状周囲面１２２を有している。注射器遠位先端１０４は、交差方向に向けられた内腔１１６から離間した、交差方向に向けられた内腔１２３を有している。交差方向に向けられた内腔１２３は、液剤投薬内腔１１９と、注射器遠位先端周囲面１２２の開口１２４と、の間を延在する。２つの交差方向に向けられた内腔１１６，１２３は、長手方向注射器アセンブリ中央線１０１を通る縦断面上にある。
注射器１０２は、流れ制御部材１２６を備えている。流れ制御部材１２６は、注射器遠位先端１０４と薬瓶アダプタ１０６との間にぴったりと入れ子装着されるチューブ状の構成を有している。流れ制御部材１２６は、近位上側１２７と遠位下側１２８とを有している。流れ制御部材１２６は、注射器遠位先端周囲面１２２にシール接触する流れ制御部材内面１３１を有する円錐状の貫通穴１２９を有している。下側１２８は、凹部１３２Ａ，１３２Ｂの直径対を有して形成される。流れ制御部材１２６は、次のように２つの流路位置での使用に対応するために、交差方向に向けられた内腔１１６と流れ連通するための流路の直径対を有している。１つは、初期流路位置において使用するための、長手方向注射器アセンブリ中央線１０１に対してオフセットされた長手方向に向けられた内腔１３３である。内腔１３３は、流れ制御部材内面１３１に形成された開口１３４と凹部１３２Ａとの間を延在する。もう１つは、最終流路位置において交差方向に向けられた２つの内腔１１６，１２３の間で流れ連通するための、流れ制御部材内面１３１に形成された溝１３６である。溝１３６は、溝基端１３７と溝先端１３８とを有している。開口１３４および溝基端１３７は、長手方向注射器アセンブリ中央線１０１に交差する同一平面上で直径方向に対向している。
薬瓶アダプタ１０６は、チューブ状の構成を有しており、また、直立近位ステム１３９と、薬瓶１０に入れ子式に取り付けるための下方に垂下する遠位スカート１４１と、直立ステム１３９と下方に垂下するスカート１４１との間の中間ネック１４２と、を備えている。直立ステム１３９は、雄ネジ１１４にネジ取り付けするための内向きのネジ突出部１４３の直径対を有している。薬瓶アダプタ１０６は、注射器遠位先端１０４から取り外すと同時に流れ制御部材１２６をその初期流路位置からその最終流路位置まで回転させるために、半回転させることを必要とする。直立ステム１３９および中間ネック１４２は、注射器遠位先端１０４および流れ制御部材１２６を取り囲む。スカート１４１は、薬瓶クラウン１３にスナップ嵌めするための内向きの突出部１４６を有する長手方向に向けられた開口１４４の直径対と、薬瓶１０にスナップ嵌めする際に薬瓶ストッパ１８を穿刺するための穿刺カニューレ先端１４７Ａを有する穿刺カニューレ１４７と、を備えている。ネック１４２は、凹部１３２Ａ，１３２Ｂの直径対内への対応する密着挿入のための突出部１４８Ａ，１４８Ｂの直径対を備えている。穿刺カニューレ１４７は、突出部１４８Ａの開口１５１と、穿刺カニューレ先端１４７Ａのところの開口１５２と、の間を延在する内腔１４９を備えている。
図４は、注射器アセンブリ１００Ａが、内腔１１６、内腔１３３および内腔１４９を介した注射器バレル内部１０８と穿刺カニューレ１４７との間の初期流路を有していることを示している。図５は、注射器アセンブリ１００Ａが、内腔１１６、溝１３６および液剤投薬内腔１１９を介した注射器バレル内部１０８と皮内ニードル１２１との間の最終流路を有していることを示している。
図６Ａ〜６Ｃは、注射器アセンブリ１００Ａの次のような使用方法を示している。図６Ａは、薬瓶アダプタ１０６が注射器遠位先端１０４に取り外し可能に取り付けられる初期セットアップ位置にある注射器アセンブリ１００Ａを示している。プランジャ１０９は、ピストン内に完全に挿入され、流れ制御部材１２６は、図４に示されるように、その初期流れ制御位置にある。臨床医は、薬瓶１０を穿刺するために、薬瓶アダプタ１０６を薬瓶１０に入れ子式に取り付ける。図６Ｂは、臨床医が注射器アセンブリ１００Ａおよび穿刺された薬瓶１０を逆さまにして、矢印Ａで示されるように液剤内容物１９を薬瓶１０から注射器１０２内に吸引する様子を示している。図６Ｃは、臨床医が注射器アセンブリ１００Ａおよび現在は空の薬瓶１０を、その直立位置まで逆さまにする様子を示している。臨床医は、薬瓶アダプタ１０６を半回転させて、それを空の薬瓶１０と一緒に注射器遠位先端１０４から取り外して、皮内ニードル１２１を露出させ、流れ制御部材１２６を、その最終流路位置まで押圧する。注射器１０２は、液剤内容物１９を投与する準備ができている。
図７は、注射器アセンブリ１００Ｂを示している。注射器アセンブリ１００Ｂは、液剤内容物を経口投与するための一体型液剤投与デバイスを構成する注射器拡大遠位先端１０４を有する注射器１０２を備えている。
図８〜１１は、構成および使用方法が注射器アセンブリ１００Ａと類似する注射器アセンブリ１００Ｃを示している。したがって、同様の部分には同様の符号を付してある。注射器アセンブリ１００Ｃは、液剤内容物を薬瓶から吸引して液剤内容物を投与するためのその流れ制御構造が注射器アセンブリ１００Ａと異なっている。
注射器遠位先端１０４は、長手方向注射器アセンブリ中央線１０１に対して交差する交差方向貫通穴１６１を有して形成されている。注射器遠位先端１０４は、長手方向注射器アセンブリ中央線１０１と同軸、かつ、交差方向貫通穴１６１の基端側に流れ連通する内腔１６２を備えている。注射器遠位先端１０４は、長手方向注射器アセンブリ中央線１０１と同軸、かつ、交差方向貫通穴１６１の先端側に流れ連通する液剤投薬内腔１６３を備えている。液剤投薬内腔１６３は、皮内ニードル１２１に適合される。
注射器１０２は、シール端部１６６を有する略チューブ状の流れ制御部材１６４を備えている。流れ制御部材１６４は、交差方向平坦切欠１６８と周囲溝１６９とを有する流れ制御部材周囲面１６７を備えている。平坦切欠１６８は、第１の切欠端１７１と第２の切欠端１７２とを有している。周囲溝１６９は、第２の切欠端１７２に流れ連通する。
薬瓶アダプタ１０６は、シール端部１６６に接触する内側半円状カム面１７３を備えている。カム面１７３は、起点カム面端部１７４と終点カム面端部１７６とを有している。起点カム面端部１７４は、長手方向注射器アセンブリ中央線１０１からの間隔Ｓ１を有している。終点カム面端部１７６は、長手方向注射器アセンブリ中央線１０１からの間隔Ｓ２を有している。間隔Ｓ１は、薬瓶アダプタ１０６の回転が初期流路位置から最終流路位置まで流れ制御部材１６４を押圧するように、間隔Ｓ２よりも大きい。
図１０は、シール端部１６６に接触する起点カム面端部１７４を有する、その初期流路位置にある注射器アセンブリ１００Ｃを示している。図１０は、注射器アセンブリ１００Ｃが、注射器バレル内部１０８と穿刺カニューレ１４７との間の、内腔１６２と、その第１の切欠端１７１のところの平坦切欠１６８と、周囲溝１６９と、液剤投薬内腔１６３と、を介した初期流路を有することを示している。
図１１は、長手方向注射器アセンブリ中央線１０１を交差方向に横切る流れ制御部材１６４を押圧しているカム面１６６を有する薬瓶アダプタ１０６を取り外した後のその最終流路位置にある注射器アセンブリ１００Ｃを示している。図１１は、注射器アセンブリ１００Ｃが、注射器バレル内部１０８と皮内ニードル１２１との間の、内腔１６２と、その第２の切欠端１７２のところの平坦切欠１６８と、周囲溝１６９と、液剤投薬内腔１６３と、を介した最終流路を有することを示している。
図１２は、薬瓶２０と液瓶３０とともに使用するための注射器アセンブリ１００Ｄを示している。薬瓶２０は、粉末状薬剤２１を備えている点において薬瓶１０と異なっている。液瓶３０は、長手方向液瓶中央線３１を有しており、また、液瓶チューブ３２と、液瓶クラウン開口３４を有するチューブ状液瓶クラウン３３と、液瓶チューブ３２と液瓶クラウン３３との間の小径液瓶ネック３６と、を備えている。液瓶３０は、液瓶チューブ３２と液瓶ネック３６との間の液瓶ショルダ３７を備えている。液瓶３０は、液瓶クラウン開口３４を塞ぐための液瓶ストッパ３８を備えている。液瓶３０は、粉末状薬剤２１と混合して液剤内容物１９を形成するために液体内容物３９を収容する。液体内容物３９は、復元目的のみの希釈剤であってもよいし、活性成分を含んでいてもよい。
注射器アセンブリ１００Ｄは、さらに、液瓶３０に入れ子式に取り付けるための液瓶アダプタ１８０を備えている。液瓶アダプタ１８０は、液瓶３０に入れ子式に取り付けるための下方に垂下するスカート１８２を有して形成された交差方向液瓶アダプタ頂部壁１８１を有している。液瓶アダプタ１８０は、液瓶アダプタ１８０を薬瓶アダプタ１０６に取り付けるために長手方向に向けられた開口１４４の直径対の内部に留めるためのクリップ１８３の直径対を有して形成される。クリップ１８３は、長手方向注射器アセンブリ中央線１０１に向けて圧縮力を加える際に液瓶アダプタ１８０を薬瓶アダプタ１０６から取り外すための、下方に垂下する指で操作されるリリース部材１８４を有している。液瓶アダプタ頂部壁１８１は、穿刺カニューレ１４７を受け入れるための円錐状直立ポート１８６を有して形成される。液瓶アダプタ頂部壁１８１は、液瓶アダプタ１８０を液瓶３０に入れ子式に取り付ける際に液瓶３０を穿刺するための下方に垂下する穿刺カニューレ１８７を有して形成される。ポート１８６は、穿刺カニューレ１８７に連続的に流れ連通し、それによって、流れ制御部材１６４の初期流路位置において注射器１０２と穿刺カニューレ１８７との間の流れ連通を提供する。
図１３Ａ〜１３Ｇは、液剤内容物１９を投与するための注射器アセンブリ１００Ｄの使用方法を示している。図１３Ａは、その初期流路位置にある注射器アセンブリ１００Ｄと、完全に挿入されたプランジャ１０９を有する空の注射器１０２と、を示している。臨床医は、液瓶３０を穿刺するために、液瓶アダプタ１８０を液瓶３０に入れ子式に取り付ける。図１３Ｂは、臨床医が注射器アセンブリ１００Ｄおよび穿刺された液瓶３０を逆さまにして、矢印Ｂで示すように液瓶３０から注射器１０２内へ液体内容物３９を吸引する様子を示している。図１３Ｃは、臨床医が注射器アセンブリ１００Ｄを逆さまにして、液瓶アダプタ１８０および現在は空の液瓶３０を取り外す様子を示している。図１３Ｄは、臨床医が、薬瓶２０を穿刺するために、液体内容物３９を有する注射器アセンブリ１００Ｄを薬瓶２０に入れ子式に取り付ける様子を示している。図１３Ｅは、臨床医が、矢印Ｃに示されるように液体内容物３９を薬瓶２０内に注入して、粉末状薬剤２１を復元して液剤内容物１９にする様子を示している。図１３Ｆは、臨床医が、注射器アセンブリ１００Ｄおよび穿刺された薬瓶２０を逆さまにして、矢印Ｄに示されるように液剤内容物１９を薬瓶２０から注射器１０２内へ吸引する様子を示している。図１３Ｇは、臨床医が、注射器アセンブリ１００Ｄおよび現在は空の薬瓶２０を、その直立位置まで逆さまにする様子を示している。臨床医は、薬瓶アダプタ１０６を半回転させて、それを空の薬瓶２０と一緒に注射器遠位先端１０４から取り外して皮内ニードル１２１を露出させ、流れ制御部材１６４をその最終流路位置まで押圧する。注射器１０２は、液剤内容物１９を投与する準備ができている。
限られた数の実施形態に関して本発明が説明されたが、本発明の多くの変更、修正および他の用途が、添付の特許請求の範囲の範囲内でなされ得ることが理解されよう。

Claims (5)

  1. 閉鎖端薬瓶チューブと、薬瓶クラウン開口を有するチューブ状薬瓶クラウンと、前記薬瓶クラウン開口を塞ぐための薬瓶ストッパと、を有する薬瓶とともに使用するための注射器アセンブリであって、
    前記薬瓶は、液剤内容物を収容し、
    前記注射器アセンブリは、長手方向注射器アセンブリ中央線を有し、
    前記注射器アセンブリは、
    （ａ）注射器近位端と注射器遠位先端とを有する注射器を備え、
    前記注射器は、注射器バレル近位端と注射器バレル遠位端とを有する開放端注射器バレルと、初期流路位置から最終流路位置まで変位可能な流れ制御部材と、を備え、
    前記注射器遠位先端は、前記液剤内容物を投与するための一体型液剤投与デバイスを有し、
    前記注射器アセンブリは、さらに、
    （ｂ）前記注射器遠位先端に手動で取り外し可能に取り付けられるチューブ状近位ステムと、前記薬瓶に入れ子式に取り付けるための下方に垂下する遠位スカートと、前記薬瓶アダプタを前記薬瓶に入れ子式に取り付ける際に前記薬瓶ストッパを穿刺するための穿刺カニューレと、を有する薬瓶アダプタを備え、
    前記穿刺カニューレは、前記注射器アセンブリの初期セットアップ位置にある前記流れ制御部材の前記初期流路位置において前記注射器バレルに流れ連通し、
    前記初期セットアップ位置では、前記薬瓶アダプタが前記注射器遠位先端に取り外し可能に最初に取り付けられ、
    前記注射器アセンブリは、前記薬瓶アダプタを前記注射器遠位先端から手動で取り外す際に、前記液剤内容物を投与することを可能にするために前記注射器バレルと前記一体型液剤投与デバイスとの間の流れ連通を可能にするために、前記薬瓶アダプタが前記流れ制御部材を前記初期流路位置から前記最終流路位置まで移動させるように構成された
    注射器アセンブリ。
  2. 請求項１に記載のアセンブリであって、
    前記手動の取り外しは、前記長手方向注射器アセンブリ中央線を中心として前記注射器に対して前記薬瓶アダプタを手動で回転させることを備える
    アセンブリ。
  3. 請求項２に記載のアセンブリであって、
    前記流れ制御部材は、
    前記長手方向注射器アセンブリ中央線を中心として回転可能であり、
    前記初期流路位置における前記注射器バレルと前記穿刺カニューレとの間の流れ連通のための初期流路内腔と、前記最終流路位置における前記注射器バレルと前記一体型液剤投与デバイスとの間の流れ連通のための最終流路内腔と、を備え、
    前記薬瓶アダプタの手動回転は、同時に、前記薬瓶アダプタを前記注射器遠位先端から取り外す間に、前記流れ制御部材を前記初期流路位置から前記最終流路位置まで回転させる
    アセンブリ。
  4. 請求項２に記載のアセンブリであって、
    前記流れ制御部材は、前記長手方向注射器アセンブリ中央線に対して、前記注射器バレルと前記穿刺カニューレとの流れ連通のための初期流路位置から、前記注射器バレルと前記一体型液剤投与デバイスとの間の流れ連通のための最終流路位置まで、交差方向に移動可能であり、
    前記薬瓶アダプタは、前記注射器遠位先端からの取り外しのために前記薬瓶アダプタを手動回転させる間に前記流れ制御部材を前記初期流路位置から前記最終流路位置まで交差方向に移動させるためのカム内面を備える
    アセンブリ。
  5. 薬剤内容物を収容する薬瓶と、液瓶と、ともに使用するための請求項１ないし請求項４のいずれか一項に記載のアセンブリであって、
    前記液瓶は、液瓶チューブと、液瓶クラウン開口を有するチューブ状液瓶クラウンと、前記液瓶クラウン開口を塞ぐための液瓶ストッパと、を備え、
    前記液瓶は、前記薬瓶内に前記液剤内容物を形成するための液剤内容物を収容し、
    前記アセンブリは、さらに、液瓶アダプタを備え、
    前記液瓶アダプタは、
    前記薬瓶アダプタから下方に垂下する前記液瓶アダプタを取り外し可能に手動で取り付けるための取り外し可能な取り付け構造と、
    前記液瓶に入れ子式に取り付けるための下方に垂下するスカートと、
    前記液瓶アダプタを前記液瓶に入れ子式に取り付ける際に前記液瓶ストッパを穿刺するための穿刺カニューレと、
    前記液瓶アダプタを前記薬瓶アダプタに取り付ける際に前記薬瓶アダプタの前記穿刺カニューレを受け入れるための円錐状ポートと、
    を備える
    アセンブリ。
JP2019510626A 2016-08-21 2017-08-16 注射器アセンブリ Withdrawn JP2019532688A (ja)

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Cited By (1)

* Cited by examiner, † Cited by third party
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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Family Cites Families (792)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US247975A (en) 1881-10-04 James h
US62333A (en) 1867-02-26 Henry holl
US254444A (en) 1882-02-28 Chaeles w
US300060A (en) 1884-06-10 Isaac v
US1021681A (en) 1911-02-13 1912-03-26 John F Jennings Valve for corrosive liquids.
US1704817A (en) 1928-01-17 1929-03-12 Okadee Company Locomotive-cylinder cock
US1930944A (en) 1932-12-21 1933-10-17 Jr William L Schmitz Measuring dispenser
US2326490A (en) 1942-06-13 1943-08-10 Harold N Perelson Fluid dispenser
US2560162A (en) 1950-02-10 1951-07-10 Becton Dickinson Co Needle structure
US2748769A (en) 1953-02-24 1956-06-05 Huber Jennie Hypodermic needle
US2830587A (en) 1954-02-01 1958-04-15 Everett Samuel James Hypodermic needles
US3059643A (en) 1954-12-10 1962-10-23 Baxter Laboratories Inc Pumping apparatus
DE1064693B (de) 1956-03-08 1959-09-03 Josef Klinger Vorrichtung zum selbsttaetigen Einstechen einer Injektionsnadel
US2931668A (en) 1956-04-30 1960-04-05 Bastian Blessing Co Coupling
US2968497A (en) 1958-02-05 1961-01-17 Avro Aircraft Ltd Self-sealing coupling
US3021325A (en) 1959-04-15 1962-02-13 Miles Lab Carbamyl substituted 2, 3, 4, 5-tetrahydrobenzodiazepine compounds
US3007461A (en) 1960-03-17 1961-11-07 Roy J Armbrust Detection system for coolant failure
US3225763A (en) 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3277893A (en) 1964-01-31 1966-10-11 Becton Dickinson Co Hypodermic projectile with barb in the cannula bevel
US3308822A (en) 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
DE1945279U (de) 1966-07-02 1966-09-01 Gruenenthal Chemie Hilfsgeraet zur herstellung von sterilen loesungen.
FR2029242A5 (en) 1969-01-21 1970-10-16 Alriq Christian Self-perforable plug for bacteriological - culture tubes
DE1913926A1 (de) 1969-03-19 1970-09-24 Hoechst Ag Zweikammerspritze
US3757981A (en) 1969-11-24 1973-09-11 Harris R Valves and valve needle syringes
US3618637A (en) 1970-02-04 1971-11-09 Deseret Pharma Rotary mixing valve
FR2114983B1 (ja) 1970-11-18 1974-03-22 Commissariat Energie Atomique
US3752598A (en) 1971-11-17 1973-08-14 United Aircraft Corp Segmented duct seal
US3788524A (en) 1971-12-22 1974-01-29 Cutter Lab Additive container
US3826261A (en) 1971-12-27 1974-07-30 Upjohn Co Vial and syringe assembly
US3782365A (en) 1973-03-13 1974-01-01 S Pinna Detector for locating veins in living bodies
US3822700A (en) 1973-03-16 1974-07-09 M Pennington Intravenous solution dispenser
US4109670A (en) 1973-05-16 1978-08-29 Slagel Roger D Combination check flow control and selector valve
US3872992A (en) 1973-08-06 1975-03-25 Pharmaco Inc Medicament vial stopper piercing and needle positioning device
US3885607A (en) 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2268707B1 (ja) 1974-04-26 1976-12-17 Becton Dickinson France
US3977555A (en) 1974-05-07 1976-08-31 Pharmaco, Inc. Protective safety cap for medicament vial
US3938520A (en) 1974-06-10 1976-02-17 Abbott Laboratories Transfer unit having a dual channel transfer member
US3957052A (en) 1974-09-13 1976-05-18 Medical Development Corporation Pumping-syringe
US3993063A (en) 1975-06-16 1976-11-23 Union Carbide Corporation Protective shielding assembly for use in loading a hypodermic syringe with radioactive material
US4051852A (en) 1975-06-26 1977-10-04 The Kendall Company Aspirating device
US4026128A (en) 1975-12-12 1977-05-31 Universal Textile Machine Corporation Faulty needle sensing
US4020839A (en) 1976-02-26 1977-05-03 Parke, Davis & Company Medicament-dispensing package
USD247975S (en) 1976-07-30 1978-05-23 Luther Ronald B Catheterization needle
US4210173A (en) 1976-12-06 1980-07-01 American Hospital Supply Corporation Syringe pumping system with valves
USD248568S (en) 1976-12-13 1978-07-18 Aaron Ismach Animal intradermal nozzle for jet injection device
US4121585A (en) 1977-01-24 1978-10-24 Becker Jr Karl E Anti backflow injection device
DE2714094C3 (de) 1977-03-30 1980-04-17 Bayer Ag, 5090 Leverkusen Vorrichtung zur Bestimmung des Wassergehaltes von isotropen Materialien mit Hilfe der Mikrowellenabsorption
US4187848A (en) 1977-07-18 1980-02-12 The Kendall Company Adapter assembly
USD254444S (en) 1977-09-01 1980-03-11 Levine Robert A Blood sampling needle
US4161178A (en) 1977-12-08 1979-07-17 Abbott Laboratories Additive transfer device
US4203443A (en) 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
USD257286S (en) 1978-03-06 1980-10-07 Tronomed International, Inc. Medical valve
US4314586A (en) 1978-08-30 1982-02-09 Tronomed International, Inc. Disposable valve
US4639019A (en) 1979-06-04 1987-01-27 Baxter Travenol Laboratories, Inc. Luer connection
US4312349A (en) 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
US4296786A (en) 1979-09-28 1981-10-27 The West Company Transfer device for use in mixing a primary solution and a secondary or additive substance
US4253501A (en) 1979-11-09 1981-03-03 Ims Limited Transfer system
US4303067A (en) 1980-01-21 1981-12-01 American Hospital Supply Corporation Medical liquid bag having an improved additive port
US4328802A (en) 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
US4376634A (en) 1980-05-30 1983-03-15 Mallinckrodt, Inc. Assay kit having syringe, dilution device and reagents within sealed container
USD267199S (en) 1980-07-17 1982-12-07 Abbott Laboratories Vial and solution container connecting device
USD268871S (en) 1980-09-18 1983-05-03 Alva Medical, Inc. Medical tubing hub for catheters or the like
USD270282S (en) 1980-10-09 1983-08-23 Abbott Laboratories Catheter insertion adapter
US4335717A (en) 1980-10-10 1982-06-22 Abbott Laboratories I.V. Administration set with retrograde volume
USD271421S (en) 1981-06-12 1983-11-15 Fetterman James W Medical valve
US4434823A (en) 1981-06-29 1984-03-06 American Hospital Supply Corporation Liquid transfer device
US4493348A (en) 1981-06-29 1985-01-15 Pur/Acc Corporation Method and apparatus for orally dispensing liquid medication
US4465471A (en) 1981-08-26 1984-08-14 Eli Lilly And Company Intravenous administration system for dry medicine
US4392850A (en) 1981-11-23 1983-07-12 Abbott Laboratories In-line transfer unit
US4410321A (en) 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4458733A (en) 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
US4475915A (en) 1982-05-07 1984-10-09 Sloane Glenn L Holder for a syringe and an ampoule
US4588396A (en) 1982-10-22 1986-05-13 Stroebel Maurice G Apparatus for gravity feed of liquid under constant hydrostatic pressure
USD280018S (en) 1982-10-25 1985-08-06 Commonwealth Industries Syringe loading guide
US4507113A (en) 1982-11-22 1985-03-26 Derata Corporation Hypodermic jet injector
US5688254A (en) 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US4752292A (en) 1983-01-24 1988-06-21 Icu Medical, Inc. Medical connector
US4505709A (en) 1983-02-22 1985-03-19 Froning Edward C Liquid transfer device
CA1215945A (en) 1983-03-20 1986-12-30 Bengt Gustavsson Fluid transfer system
US4676530A (en) 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
US4778447A (en) 1983-05-20 1988-10-18 Travenol European Research & Development Center Connectors
JPS6026391U (ja) 1983-07-30 1985-02-22 株式会社ハーマン 管接続具
US4532969A (en) 1983-09-21 1985-08-06 Kwaan Hau C Fluid withdrawal and instillation device
US4573993A (en) 1983-09-29 1986-03-04 Instafil, Inc. Fluid transfer apparatus
USD284603S (en) 1983-11-25 1986-07-08 Loignon Edward G Syphon fitting
US4743243A (en) 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
IT1173370B (it) 1984-02-24 1987-06-24 Erba Farmitalia Dispositivo di sicurezza per collegare una siringa alla imboccatura di un flacone contenente un farmaco o di un tubicino per l'erogazione del farmaco della siringa
US4585446A (en) 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4581014A (en) 1984-04-03 1986-04-08 Ivac Corporation Fluid infusion system
US5088996A (en) 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4697622A (en) 1984-06-01 1987-10-06 Parker Hannifin Corporation Passive filling device
US4604093A (en) 1984-06-12 1986-08-05 I-Flow Corporation Apparatus and method for administering multiple fluid infusions
US5113904A (en) 1984-07-13 1992-05-19 Aslanian Jerry L Flow control device for administration of intravenous fluids
US4607671A (en) 1984-08-21 1986-08-26 Baxter Travenol Laboratories, Inc. Reconstitution device
JPS6168045A (ja) 1984-09-10 1986-04-08 テルモ株式会社 医療用活栓
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4614437A (en) 1984-11-02 1986-09-30 Dougherty Brothers Company Mixing container and adapter
USD300060S (en) 1985-02-25 1989-02-28 William Cook Europe A/S Biopsy cannula
SE8501656D0 (sv) 1985-04-03 1985-04-03 Mediplast Ab Overforingsanordning
US4721133A (en) 1985-09-26 1988-01-26 Alcon Laboratories, Inc. Multiple use valving device
US4675020A (en) 1985-10-09 1987-06-23 Kendall Mcgaw Laboratories, Inc. Connector
US4667927A (en) 1985-11-08 1987-05-26 Rao Medical Devices, Inc. Liquid flow metering device
DE3600496A1 (de) 1986-01-10 1987-07-16 Josef Magasi Punktionskanuele, deren griff sowie verfahren zu deren herstellung
US4865592A (en) 1986-02-20 1989-09-12 Becton, Dickinson And Company Container and needle assembly
US4834152A (en) 1986-02-27 1989-05-30 Intelligent Medicine, Inc. Storage receptacle sealing and transfer apparatus
US4735608A (en) 1986-05-14 1988-04-05 Del F. Kahan Apparatus for storing and reconstituting antibiotics with intravenous fluids
US5049129A (en) 1986-05-29 1991-09-17 Zdeb Brian D Adapter for passive drug delivery system
USD303013S (en) 1986-06-19 1989-08-22 Pacesetter Infusion, Ltd. Female luer connector
SE461765B (sv) 1986-07-10 1990-03-26 Haessle Ab Anordning foer frisaettning av substans
IT1201801B (it) 1986-08-04 1989-02-02 Pietro Cosmai Caricatore miscelatore per iniettori transcutanei
IE60235B1 (en) 1986-09-18 1994-06-15 Kabi Pharmacia Ab "Connector and disposable assembly utilising said connector"
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4683975A (en) 1986-09-30 1987-08-04 General Motors Corporation Vehicle power window control
US4797898A (en) 1986-11-21 1989-01-10 Racal Data Communications Inc. Method and apparatus for equalization of data transmission system
US4832690A (en) 1987-01-23 1989-05-23 Baxter International Inc. Needle-pierceable cartridge for drug delivery
US4729401A (en) 1987-01-29 1988-03-08 Burron Medical Inc. Aspiration assembly having dual co-axial check valves
US5041105A (en) 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4787898A (en) 1987-05-12 1988-11-29 Burron Medical Inc. Vented needle with sideport
US4758235A (en) 1987-05-26 1988-07-19 Tu Ho C Cardiopulmonary resuscitation medication assembly
AU101237S (en) 1987-06-18 1988-09-08 Ab Astra Transfer cannula
US5178607A (en) 1987-07-31 1993-01-12 Lynn Lawrence A Blood aspiration assembly septum and blunt needle aspirator
IT211830Z2 (it) 1987-09-22 1989-05-25 Farmitalia Carl Erba S P A Dispositivo di sicurezza perl'introduzione ed il prelievo di liquidi in e da flaconi di farmaci e simili.
US4804366A (en) 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
USD314050S (en) 1987-11-27 1991-01-22 Terumo Kabushiki Kaisha Medical connector
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
DE3804429A1 (de) 1988-02-12 1989-08-24 Schleicher & Schuell Gmbh Einmalfilter
US4932944A (en) 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4857062A (en) 1988-03-09 1989-08-15 Medical Parameters, Inc. Catheter introducer valve
US4931040A (en) 1988-04-13 1990-06-05 Habley Medical Technology Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule
US4871463A (en) 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US4898209A (en) 1988-09-27 1990-02-06 Baxter International Inc. Sliding reconstitution device with seal
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5122124A (en) 1988-12-14 1992-06-16 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5301685A (en) 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US5035686A (en) 1989-01-27 1991-07-30 C. R. Bard, Inc. Catheter exchange system with detachable luer fitting
USD328788S (en) 1989-05-01 1992-08-18 Terumo Kabushiki Kaisha Connector for catheter
US5135492A (en) 1989-06-26 1992-08-04 University Of Florida Arterial/venous fluid transfer system
USD341420S (en) 1989-07-14 1993-11-16 Ivac Corporation Combined universal spike and drip chamber
US4967797A (en) 1989-08-16 1990-11-06 Manska Wayne E Tap valve
US5053015A (en) 1989-08-30 1991-10-01 The Kendall Company Locking catheter adapter
US4997430A (en) 1989-09-06 1991-03-05 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Method of and apparatus for administering medicament to a patient
US5578015A (en) 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
EP0462255B1 (fr) 1990-01-08 1994-09-21 Becton Dickinson France S.A. Flacon de stockage et de transfert a double compartiment
US5304163A (en) 1990-01-29 1994-04-19 Baxter International Inc. Integral reconstitution device
US5125915A (en) 1990-03-02 1992-06-30 Cardiopulmonics, Inc. Locking y-connector for selective attachment to exterior of medical tubing
US5061248A (en) 1990-04-04 1991-10-29 Sacco John J Injection port safety shield
USRE38996E1 (en) 1990-04-20 2006-02-28 Becton, Dickinson And Company Needle tip cover
US5006114A (en) 1990-04-20 1991-04-09 Rogers Bobby E Medical valve assembly
JPH0426403A (ja) 1990-05-22 1992-01-29 Itaru Taniguchi 椅子
US5104387A (en) 1990-05-25 1992-04-14 St. Jude Medical, Inc. Bi-planar fluid control valve
US5045066A (en) 1990-06-07 1991-09-03 Smith & Nephew, Inc. Dental needle with stick resistant protective sleeve
US5203775A (en) 1990-09-18 1993-04-20 Medex, Inc. Needleless connector sample site
US5515871A (en) 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
US5125908A (en) 1990-10-19 1992-06-30 Cohen Milton J Hypodermic syringe with protective holder
US5201717A (en) 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
US5232029A (en) 1990-12-06 1993-08-03 Abbott Laboratories Additive device for vial
US5183469A (en) 1991-05-10 1993-02-02 Becton, Dickinson And Company Device for the removal and replacement of a needle shield
DE4122221A1 (de) 1991-07-04 1993-03-18 Axel Von Brand Transfer- und entnahmespike
DE4122476A1 (de) 1991-07-06 1993-01-07 Leopold Pharma Gmbh Verfahren und vorrichtung zum ueberleiten von zwei oder mehr sterilen fluessigkeiten im geschlossenen system
US5288290A (en) 1991-09-25 1994-02-22 Alcon Surgical, Inc. Multi-ported valve assembly
US5242432A (en) 1991-09-26 1993-09-07 Ivac Needleless adapter
WO1993010001A1 (en) 1991-11-21 1993-05-27 Gds Technology, Inc. Fluid transfer device
US5171230A (en) 1991-11-29 1992-12-15 Medex, Inc. Fast flush catheter valve
US5304165A (en) 1991-12-09 1994-04-19 Habley Medical Technology Corporation Syringe-filling medication dispenser
US5247972A (en) 1991-12-17 1993-09-28 Whittier Medical, Inc. Alignment guide for hypodermic syringe
DE69233329T2 (de) 1991-12-18 2004-08-05 Icu Medical, Inc., Irvine Verfahren zum Flüssigkeitstransfer
US5279597A (en) 1992-01-13 1994-01-18 Arrow International Investment Corp. Catheter compression clamp
CA2093560C (en) 1992-04-10 2005-06-07 Minoru Honda Fluid container
US5328474A (en) 1992-04-13 1994-07-12 B. Braun Medical Inc. Tamper resistant syringe cap
JP2605345Y2 (ja) 1992-05-01 2000-07-10 株式会社大塚製薬工場 薬剤容器
JPH05317383A (ja) 1992-05-19 1993-12-03 Nissho Corp 薬剤容器との連通手段を備えた溶解液容器
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
USD349648S (en) 1992-06-02 1994-08-16 Sterling Winthrop Inc. Closure for vials
US5232109A (en) 1992-06-02 1993-08-03 Sterling Winthrop Inc. Double-seal stopper for parenteral bottle
GB9211912D0 (en) 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
JPH0686738U (ja) 1992-06-16 1994-12-20 森下ルセル株式会社 医療用容器
USD357733S (en) 1992-07-28 1995-04-25 Pall Corporation Spike detector
US5300034A (en) 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
DE9210674U1 (ja) 1992-08-07 1993-07-22 B. Braun Melsungen Ag, 34212 Melsungen, De
JPH08500036A (ja) 1992-08-07 1996-01-09 ザ・ウエスト・カンパニー・インコーポレーテッド ニードルレス型のアクセスストッパ
US5308483A (en) 1992-08-27 1994-05-03 Gelman Sciences Inc. Microporous filtration funnel assembly
US5344417A (en) 1992-09-11 1994-09-06 Becton, Dickinson And Company Universal fitting for inoculation receptacles
US5334163A (en) 1992-09-16 1994-08-02 Sinnett Kevin B Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue
US5603706A (en) 1992-09-29 1997-02-18 Wyatt; Philip Infusion apparatus
US5334179A (en) 1992-10-16 1994-08-02 Abbott Laboratories Latching piercing pin for use with fluid vials of varying sizes
US5562696A (en) 1992-11-12 1996-10-08 Cordis Innovasive Systems, Inc. Visualization trocar
US5385547A (en) 1992-11-19 1995-01-31 Baxter International Inc. Adaptor for drug delivery
US5547471A (en) 1992-11-19 1996-08-20 Baxter International Inc. In-line drug delivery device for use with a standard IV administration set and a method for delivery
US5496274A (en) 1992-11-23 1996-03-05 Becton, Dickinson And Company Locking safety needle assembly
DK0625917T3 (da) 1992-12-15 1998-09-28 Sanofi Sa Indretning til præparation af en opløsning, en suspension eller en emulsion af en medicinsk substans
JP2604240Y2 (ja) 1992-12-25 2000-04-24 川澄化学工業株式会社 医療用具
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
JPH06239352A (ja) 1993-02-05 1994-08-30 Nissho Corp 溶解液注入セット
US5269768A (en) 1993-02-08 1993-12-14 Smiths Industries Medical Systems, Inc. Valved suction catheter
US5766211A (en) 1993-02-08 1998-06-16 Wood; Jan Medical device for allowing insertion and drainage into a body cavity
US5464111A (en) 1993-03-03 1995-11-07 Sterling Winthrop Closure for medication container
US5312377A (en) 1993-03-29 1994-05-17 Dalton Michael J Tapered luer connector
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5607439A (en) 1993-06-24 1997-03-04 Yoon; Inbae Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion
CA2124970A1 (en) 1993-06-29 1994-12-30 R. Hayes Helgren Pointed adapter for blunt entry device
US5429614A (en) 1993-06-30 1995-07-04 Baxter International Inc. Drug delivery system
US5445630A (en) 1993-07-28 1995-08-29 Richmond; Frank M. Spike with luer fitting
US5364387A (en) 1993-08-02 1994-11-15 Becton, Dickinson And Company Drug access assembly for vials and ampules
US5397303A (en) 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5451374A (en) 1993-08-23 1995-09-19 Incutech, Inc. Medicine vessel stopper
US6146362A (en) 1993-08-27 2000-11-14 Baton Development, Inc. Needleless IV medical delivery system
EP0717611B1 (fr) 1993-09-07 1998-08-12 Debiotech S.A. Dispositif de seringue pour le melange de deux composes
SE9303178D0 (sv) 1993-09-29 1993-09-29 Kabi Pharmacia Ab Improvements in injection cartridges
US5806831A (en) 1993-10-13 1998-09-15 Paradis; Joseph R. Control of fluid flow with internal cannula
US5509433A (en) 1993-10-13 1996-04-23 Paradis; Joseph R. Control of fluid flow
US5699821A (en) 1993-10-13 1997-12-23 Paradis; Joseph R. Control of fluid flow
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
DE4408498C2 (de) 1993-11-16 1997-06-12 Christian Eichler Umfülleinrichtung für die Medizin und die Pharmazie
US5348544A (en) 1993-11-24 1994-09-20 Becton, Dickinson And Company Single-handedly actuatable safety shield for needles
US5549577A (en) 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5554128A (en) 1994-03-09 1996-09-10 Joseph K. Andonian Syringe and vial connector
US5482446A (en) 1994-03-09 1996-01-09 Baxter International Inc. Ambulatory infusion pump
US5658133A (en) 1994-03-09 1997-08-19 Baxter International Inc. Pump chamber back pressure dissipation apparatus and method
US5520659A (en) 1994-03-09 1996-05-28 Joseph K. Andonian Syringe needle cover and vial connector
US5454805A (en) 1994-03-14 1995-10-03 Brony; Seth K. Medicine vial link for needleless syringes
US5462317A (en) 1994-03-23 1995-10-31 Keller; Wilhelm A. Adapter for a mixing or dispensing device
US5527306A (en) 1994-04-18 1996-06-18 Haining; Michael L. Vial adapter
USD362718S (en) 1994-04-22 1995-09-26 Mcgaw, Inc. Turn lock cannula
DE4414697C2 (de) 1994-04-27 1998-06-18 Caremed Vertriebsgesellschaft Vorrichtung zum Transferieren und Entnehmen von Flüssigkeiten aus Flaschen, Beuteln oder ähnlichen Behältnissen für medizinische Zwecke
US5832971A (en) 1994-05-19 1998-11-10 Becton, Dickinson And Company Syringe filling and delivery device
US5746733A (en) 1994-05-19 1998-05-05 Becton, Dickinson And Company Syringe filling and delivery device
JP4221515B2 (ja) 1994-05-23 2009-02-12 セファロン リミテッド 製剤調製機
US5649637A (en) 1994-06-02 1997-07-22 Automatic Liquid Packaging, Inc. Torque-resistant closure for a hermetically sealed container
JP3456019B2 (ja) 1994-06-17 2003-10-14 ニプロ株式会社 液体導入針およびそれを用いた乾燥製剤溶解補助具
US5470319A (en) 1994-06-20 1995-11-28 Critical Device Corporation Needleless injection site
US6183448B1 (en) 1994-06-20 2001-02-06 Bruno Franz P. Mayer Needleless injection site
EP1181921A3 (en) 1994-06-24 2002-03-06 ICU Medical, Inc. Fluid transfer device and method of use
EP0692235A1 (en) 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
GB9419316D0 (en) 1994-09-24 1994-11-09 Robertson William F A needle guard
FR2726768A1 (fr) 1994-11-14 1996-05-15 Debiotech Sa Dispositif de seringue fixable sur un flacon
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US5531695A (en) 1994-12-22 1996-07-02 Sherwood Medical Company Tamper evident sleeve
US5616136A (en) 1995-01-09 1997-04-01 Med-Safe Systems, Inc. Quick release needle removal apparatus
USD369406S (en) 1995-01-13 1996-04-30 Sanofi Winthrop, Inc. Cannula
US5653686A (en) 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5492147A (en) 1995-01-17 1996-02-20 Aeroquip Corporation Dry break coupling
GB9501218D0 (en) 1995-01-21 1995-03-15 Boc Group Plc Medical devices
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5674195A (en) 1995-02-06 1997-10-07 Truthan; Charles Edwin Syringe apparatus and method of mixing liquid medicants within a syringe
DE19504413A1 (de) 1995-02-10 1996-08-22 Pharmacia Gmbh Überleitungsgerät
DE19506163C2 (de) 1995-02-22 1998-01-29 Hans Mueller Vorrichtung zur Behandlung von Blut
US5584819A (en) 1995-03-13 1996-12-17 Kopfer; Rudolph J. Nested blunt/sharp injection assembly
IL114960A0 (en) * 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5651776A (en) 1995-03-22 1997-07-29 Angiodynamics, Inc. Luer-type connector
ATE181909T1 (de) 1995-04-04 1999-07-15 Kuraray Co Verfahren zur herstellung von 6-methylheptan-2-on
US5566729A (en) 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
DE19513666C1 (de) 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen
US5902280A (en) 1995-04-13 1999-05-11 Advanced Cytometrix, Inc. Aspiration needle apparatus incorporating its own vacuum and method and adapter for use therewith
US5562686A (en) 1995-04-19 1996-10-08 United States Surgical Corporation Apparaus and method for suturing body tissue
US5968022A (en) 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
SE509950C2 (sv) 1995-05-02 1999-03-29 Carmel Pharma Ab Anordning för administrering av toxisk vätska
NZ286445A (en) 1995-05-16 1997-12-19 Ivac Corp Needleless luer connector: deformable piston occludes bore
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
MX9602398A (es) 1995-06-23 1997-02-28 Kimberly Clark Co Material polimerico modificado teniendo humectabilidad mejorada.
US5685845A (en) 1995-07-11 1997-11-11 Becton, Dickinson And Company Sterile resealable vial connector assembly
US5616203A (en) 1995-07-14 1997-04-01 Merit Medical Method of manufacturing a split ring airless rotatable connector
USD388172S (en) 1995-07-27 1997-12-23 E-Z Kare Good Health Systems, Inc. Nasal dilator
JPH0956782A (ja) 1995-08-24 1997-03-04 Kanae:Kk 受動的薬剤放出用具
FR2738550B1 (fr) 1995-09-11 1997-11-07 Biodome Dispositif d'obturation d'un recipient lui-meme ferme, ensemble pour dispenser un produit comprenant un tel recipient et un tel dispositif d'obturation
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
CA2185494A1 (en) 1995-09-27 1997-03-28 Jean-Pierre Grimard Resealable vial with connector assembly having a membrane and pusher
US5702019A (en) 1995-09-27 1997-12-30 Becton Dickinson France S.A. Vial having resealable membrane assembly activated by a medical delivery device
KR100469207B1 (ko) 1995-10-20 2005-03-16 화이자 헬스 에이비 전자식주입조정장치
WO1997015267A2 (de) 1995-10-20 1997-05-01 Schering Aktiengesellschaft Adapter zum entnehmen einer flüssigkeit aus einem mit einem stopfen verschlossenen behältnis
US5611576A (en) 1995-11-24 1997-03-18 Industrie Borla Spa Female coupling element for haemodialysis medical equipment
US5833213A (en) 1995-12-29 1998-11-10 Rymed Technologies, Inc. Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe
WO1997025015A1 (en) 1996-01-11 1997-07-17 Duoject Medical Systems Inc. Delivery system for pharmaceuticals packed in pharmaceutical vials
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US5879337A (en) 1997-02-27 1999-03-09 Injectimed, Inc. Needle tip guard for hypodermic needles
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US5810792A (en) 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
USD393722S (en) 1996-04-04 1998-04-21 Icu Medical, Inc. Locking blunt cannula
EP0895466A1 (en) 1996-04-22 1999-02-10 Abbott Laboratories Container closure system
GB9609563D0 (en) 1996-05-08 1996-07-10 Sterimatic Holdings Ltd Venting devices
DE19619026A1 (de) 1996-05-10 1997-11-13 Trinova Gmbh Schnellkupplung
US5752942A (en) 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US5897526A (en) 1996-06-26 1999-04-27 Vaillancourt; Vincent L. Closed system medication administering system
US5728087A (en) 1996-07-30 1998-03-17 Bracco Diagnostics, Inc. Universal flexible plastic container with multiple access ports of inverted Y shape configuration
US6296621B1 (en) 1996-08-23 2001-10-02 Baxter International Inc. Receptacle for passive drug delivery
US5871110A (en) 1996-09-13 1999-02-16 Grimard; Jean-Pierre Transfer assembly for a medicament container having a splashless valve
US5873872A (en) 1996-09-17 1999-02-23 Becton Dickinson And Company Multipositional resealable vial connector assembly for efficient transfer of liquid
CA2211629A1 (en) 1996-09-17 1998-03-17 Bernard Sams Vial connector assembly for a medicament container
FR2753624B1 (fr) 1996-09-25 1999-04-16 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
US5738144A (en) 1996-10-11 1998-04-14 Aeroquip Corporation Luer connecting coupling
US5817082A (en) 1996-11-08 1998-10-06 Bracco Diagnostics Inc. Medicament container closure with integral spike access means
US5895383A (en) 1996-11-08 1999-04-20 Bracco Diagnostics Inc. Medicament container closure with recessed integral spike access means
US5941848A (en) 1996-11-14 1999-08-24 Baxter International Inc. Passive drug delivery apparatus
US6883778B1 (en) 1996-11-18 2005-04-26 Nypro Inc. Apparatus for reducing fluid drawback through a medical valve
ES2217435T3 (es) 1996-11-18 2004-11-01 Nypro, Inc. Valvula actuada por conector conificado tipo luer.
US5868710A (en) 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
FR2756811B1 (fr) 1996-12-06 1999-02-05 Valois Dispositif de distribution de produit fluide du type bicomposant
GB9700177D0 (en) 1997-01-07 1997-02-26 Nycomed Imaging As Container
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5891129A (en) 1997-02-28 1999-04-06 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
USD405522S (en) 1997-04-18 1999-02-09 Vital Signs Inc. Breathing tube for conveying oxygen or anesthesia gas to lungs and conveying exhaled gas away from lungs of patient
US5911710A (en) 1997-05-02 1999-06-15 Schneider/Namic Medical insertion device with hemostatic valve
US6530900B1 (en) 1997-05-06 2003-03-11 Elan Pharma International Limited Drug delivery device
US5772652A (en) 1997-05-14 1998-06-30 Comar, Inc. Stab cap for a vial having a puncturable seal
US6042433A (en) 1997-05-29 2000-03-28 The Whitaker Corporation Electrical contact
JPH1147274A (ja) 1997-06-03 1999-02-23 Takeda Chem Ind Ltd ２室型注射器及び２室型注射器用接続具
IT1293856B1 (it) 1997-06-27 1999-03-10 Borla Ind Dispositivo trasduttore-protettore per linee biomedicali di emodialisi
US5755696A (en) 1997-06-30 1998-05-26 Becton, Dickinson And Company Syringe filling and delivery device
US5899468A (en) 1997-07-02 1999-05-04 Rehrig Pacific Company Organic waste cart with vented lid
US5820621A (en) 1997-07-29 1998-10-13 Becton, Dickinson And Company Medical fluid transfer and delivery device
JPH11104215A (ja) 1997-08-12 1999-04-20 Becton Dickinson Fr Sa ガラス瓶コネクタアセンブリ
US7125397B2 (en) 1997-08-20 2006-10-24 B. Braun Melsungen Ag Protective device for an injection needle
IL121605A (en) 1997-08-22 2001-03-19 Medimop Medical Projects Ltd Fluid access assembly and a method for preparing a liquid drug
US5834744A (en) 1997-09-08 1998-11-10 The Rubbright Group Tubular microwave applicator
US5919182A (en) 1997-09-12 1999-07-06 Becton, Dickinson And Company Medical fluid transfer and delivery device
US6089541A (en) 1998-09-10 2000-07-18 Halkey-Roberts Corporation Valve having a valve body and a deformable stem therein
US6036171A (en) 1997-09-17 2000-03-14 Halkey-Roberts Corporation Swabbable valve assembly
US6090093A (en) 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US5925029A (en) 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US5935112A (en) 1997-10-15 1999-08-10 Stevens; Brian W. Hemostasis valve with catheter/guidewire seals
US5902298A (en) 1997-11-07 1999-05-11 Bracco Research Usa Medicament container stopper with integral spike access means
USD399559S (en) 1997-11-12 1998-10-13 Incutech, Inc. Pediatric catheter connector
IT236233Y1 (it) 1997-11-26 2000-08-08 Eurospital S P A Dispositivo per il collegamento di un contenitore di prodottofarmaceutico ad una sacca di prodotto liquido per effettuare il
US6019750A (en) 1997-12-04 2000-02-01 Baxter International Inc. Sliding reconstitution device with seal
US6457488B2 (en) 1998-01-08 2002-10-01 George Loo Stopcock having axial port for syringe twist actuation
US6186997B1 (en) 1998-01-20 2001-02-13 Bracco Research Usa Multiple use universal connector
US6179822B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Single use universal access device/medical container assembly
US6179823B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Multiple use universal connector flexible medical container assembly
FR2773735B1 (fr) 1998-01-20 2000-02-25 Becton Dickinson France Dispositif de confinement etanche
US6096011A (en) 1998-01-29 2000-08-01 Medrad, Inc. Aseptic connector and fluid delivery system using such an aseptic connector
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6080132A (en) 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6221065B1 (en) 1998-04-03 2001-04-24 Filtertek Inc. Self-priming needle-free “Y”-adapter
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
US5921419A (en) 1998-05-04 1999-07-13 Bracco Research Usa Universal stopper
USD422357S (en) 1998-05-04 2000-04-04 Bracco Research Usa Stopper for medication container
US6692478B1 (en) 1998-05-04 2004-02-17 Paradis Joseph R Swabbable needleless vial access
US6117114A (en) 1998-05-07 2000-09-12 Paradis; Joseph R. Swabbable needleless valve adaptations
USD410740S (en) 1998-05-11 1999-06-08 Incutech, Inc. Pediatric catheter connector
CA2262477C (en) 1998-05-16 2008-02-12 Bracco International B.V. Multiple use universal stopper
BR9910754A (pt) 1998-05-29 2001-07-03 Lawrence A Lynn Receptor luer e método para transferência de fluido
US5941850A (en) 1998-06-29 1999-08-24 Shah; Binod Safety cannula
US6245044B1 (en) 1998-07-17 2001-06-12 Becton, Dickinson And Company Variable extension combined spinal/epidural needle set and method for its use
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6276568B1 (en) 1998-08-21 2001-08-21 Pharmacia & Upjohn Company Spray bottle grip
GB2359754B (en) 2000-03-03 2004-04-28 Nmt Group Plc Needle sheath
US20050137566A1 (en) 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
AR021220A1 (es) 1998-09-15 2002-07-03 Baxter Int DISPOSITIVO DE CONEXIoN PARA ESTABLECER UNA COMUNICACIoN FLUíDA ENTRE UN PRIMER RECIPIENTE Y UN SEGUNDO RECIPIENTE.
US6022339A (en) 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
FR2783808B1 (fr) 1998-09-24 2000-12-08 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6726672B1 (en) 1998-09-28 2004-04-27 Icu Medical, Inc. Intravenous drug access system
US6113068A (en) 1998-10-05 2000-09-05 Rymed Technologies Swabbable needleless injection port system having low reflux
USD430291S (en) 1998-10-08 2000-08-29 Becton, Dickinson And Company Medical container
USD431864S (en) 1998-11-24 2000-10-10 Becton Dickinson And Company Tamper evident cap for a tip cap
US6364866B1 (en) 1999-01-22 2002-04-02 Douglas Furr Syringe loading aid
USD427308S (en) 1999-01-22 2000-06-27 Medimop Medical Projects Ltd. Vial adapter
FR2789369B1 (fr) 1999-02-10 2001-04-27 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
EP1034809A1 (en) 1999-02-26 2000-09-13 F. Hoffmann-La Roche Ag Administering device for medication
USD445895S1 (en) 1999-03-05 2001-07-31 Maersk Medical A/S Funnel for a catheter
JP2000262497A (ja) 1999-03-16 2000-09-26 Sekisui Chem Co Ltd 分注器具、分注システム及び分注方法
FR2790948B1 (fr) 1999-03-18 2001-06-22 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule
US6099511A (en) 1999-03-19 2000-08-08 Merit Medical Systems, Inc. Manifold with check valve positioned within manifold body
USD427309S (en) 1999-04-30 2000-06-27 Incutech, Inc. Pediatric catheter connector
US6231552B1 (en) 1999-05-04 2001-05-15 Saf-T-Med, Inc. Threaded latching mechanism
US6092692A (en) 1999-05-10 2000-07-25 Riskin; Jane G. Medication applicator with incident reminder system
US6156025A (en) 1999-06-17 2000-12-05 Bracco Research Usa Inc. Twist valve
JP4329954B2 (ja) 1999-06-29 2009-09-09 東洋ゴム工業株式会社 空気入りタイヤ
US6706022B1 (en) 1999-07-27 2004-03-16 Alaris Medical Systems, Inc. Needleless medical connector with expandable valve mechanism
USD428141S (en) 1999-08-04 2000-07-11 Pharmacia & Upjohn Company Spray bottle grip
US6348044B1 (en) 1999-10-12 2002-02-19 George D. N. Coletti Method and apparatus for recapping single-use hypodermic needles
CA2387893C (en) 1999-10-22 2009-04-14 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US7198618B2 (en) 1999-11-04 2007-04-03 Tyco Healthcare Group Lp Safety shield for medical needles
US6253804B1 (en) 1999-11-05 2001-07-03 Minimed Inc. Needle safe transfer guard
FR2800713B1 (fr) 1999-11-05 2002-01-04 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard
US6632201B1 (en) 1999-11-17 2003-10-14 Baxter International Inc. Locking needle protector
US6428505B1 (en) 1999-11-19 2002-08-06 Prismedical Corporation In-line IV drug delivery pack with controllable dilution
DE19960226C1 (de) 1999-12-14 2001-05-10 Fresenius Ag Sterilitäterhaltendes Konnektionssystem für medizinische Systeme und dessen Verwendung
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
USD445501S1 (en) 2000-01-24 2001-07-24 Bracco Diagnostics, Inc. Vial access adapter
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US6706031B2 (en) 2000-02-15 2004-03-16 Comar, Inc. Needleless access apparatus and system
CA2390477C (en) 2000-02-16 2010-05-18 B D Medico S.A.R.L. Method for reconstituting an injection liquid and an injection appliance for carrying out such a method
US6530903B2 (en) 2000-02-24 2003-03-11 Xiping Wang Safety syringe
US6173868B1 (en) 2000-03-08 2001-01-16 Calmar Inc. Nasal sprayer with folding actuator
US6652509B1 (en) 2000-04-03 2003-11-25 Abbott Laboratories Housing capable of connecting a container to a medical device
JP4372310B2 (ja) 2000-04-10 2009-11-25 ニプロ株式会社 混注用アダプター
US6972002B2 (en) 2000-04-28 2005-12-06 Specialized Health Products, Inc. Passively activated safety shield for a catheter insertion needle
US6884253B1 (en) 2000-05-16 2005-04-26 Taut, Inc. Penetrating tip for trocar assembly
US6343629B1 (en) 2000-06-02 2002-02-05 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
US6499617B1 (en) 2000-07-17 2002-12-31 Brocco Diagnostics, Inc. Rotary seal stopper
JP2002035140A (ja) 2000-07-21 2002-02-05 Terumo Corp コネクタ
JP5058425B2 (ja) 2000-08-02 2012-10-24 ベクトン・ディキンソン・アンド・カンパニー ペン針および安全シールドシステム
JP2004508897A (ja) 2000-09-21 2004-03-25 エラン・ファルマ・インターナショナル・リミテッド 再形成および注入システム
FR2815328B1 (fr) 2000-10-17 2002-12-20 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
JP2002191695A (ja) 2000-10-20 2002-07-09 Mitsubishi Pencil Co Ltd 針先カバー部材、針先カバー部材付き注射針の組立方法、針ガード部材付き注射針および針ガード部材付き注射器
US6769430B1 (en) 2000-10-31 2004-08-03 Kimberly-Clark Worldwide, Inc. Heat and moisture exchanger adaptor for closed suction catheter assembly and system containing the same
JP2002177392A (ja) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc 注射器安全装置
US6666852B2 (en) 2000-12-04 2003-12-23 Bracco Diagnostics, Inc. Axially activated vial access adapter
FR2817566B1 (fr) 2000-12-04 2003-02-07 Freyssinet Int Stup Toron individuellement protege, son utilisation dans la construction, et procede de fabrication
US20020087118A1 (en) 2000-12-29 2002-07-04 Duoject Medical Systems Inc. Pharmaceutical delivery system
US6558365B2 (en) 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
USD468015S1 (en) 2001-01-22 2002-12-31 Astra Tech Ab Combined connector with valve and non-return valve for medical equipment
US6474375B2 (en) 2001-02-02 2002-11-05 Baxter International Inc. Reconstitution device and method of use
US20020147429A1 (en) 2001-02-20 2002-10-10 Cowan Kevin P. Syringes, connectors, and syringe and connector systems for use in fluid delivery systems
US6656433B2 (en) 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
US6685692B2 (en) 2001-03-08 2004-02-03 Abbott Laboratories Drug delivery system
US20020138045A1 (en) 2001-03-20 2002-09-26 Moen Michael E. Quick connect fitting
JP4163961B2 (ja) 2001-03-27 2008-10-08 イーライ リリー アンド カンパニー 注入ペンカートリッジ内で薬品を用意するための横噴出注射器針を含むキット
US6581593B1 (en) 2001-04-03 2003-06-24 Darren A. Rubin Universal oxygen connector system
WO2002089900A1 (en) 2001-05-07 2002-11-14 Nexell Therapeutics Inc. Fluid connector devices and methods of use
JP2002355318A (ja) 2001-06-01 2002-12-10 Terumo Corp 弁体付コネクター
EP1264609B1 (en) 2001-06-06 2006-01-18 Graziano Azzolini High-sterility and high-capacity connector for lines for outflow from bottles
USD457954S1 (en) 2001-06-19 2002-05-28 Becton, Dickinson And Company Syringe tip cap
JP2003033441A (ja) 2001-07-23 2003-02-04 Terumo Corp 三方活栓
US6453949B1 (en) 2001-08-08 2002-09-24 Sam Chau Plug for medical bayonet connectors and drug infusion ports
US6745998B2 (en) 2001-08-10 2004-06-08 Alaris Medical Systems, Inc. Valved male luer
USD476731S1 (en) 2001-08-27 2003-07-01 Kimberly-Clark Worldwide, Inc. Bendable connector
DE10142450C1 (de) 2001-08-31 2003-06-18 Aventis Behring Gmbh Vorrichtung zum Zusammenführen von Komponenten unter sterilen Bedingungen
FR2829691B1 (fr) 2001-09-17 2004-07-09 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une carpule
US7354422B2 (en) 2001-09-26 2008-04-08 B. Braun Melsungen Ag Spring launched needle safety clip
JP4817564B2 (ja) 2001-09-28 2011-11-16 株式会社細川洋行 ニードルケース及び輸液容器
DE10149251B4 (de) 2001-10-05 2007-04-19 Sartorius Ag Vorrichtung zur genetischen Immunisierung durch Einbringen von Wirkstoffen in ein Gewebe und Verfahren zur Herstellung einer Injektionslösung
US20030069550A1 (en) 2001-10-06 2003-04-10 Sharp M. Keith Hypodermic needle
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
US20030073971A1 (en) 2001-10-17 2003-04-17 Saker Gordon Mark Universal connector and method for securing flexible tube assemblies
WO2003041788A1 (fr) 2001-11-14 2003-05-22 Jms Co., Ltd. Robinet d'arret a trois voies et circuits de transfusion liquide ou sanguine utilisant ce robinet
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
US6802490B2 (en) 2001-11-29 2004-10-12 Alaris Medical Systems, Inc. Needle free medical connector with expanded valve mechanism and method of fluid flow control
CN1294997C (zh) 2001-11-30 2007-01-17 诺沃挪第克公司 安全针组件
EP1453561B1 (en) 2001-12-13 2016-08-31 Becton Dickinson and Company Needle closure system removal device
EP1323403B1 (en) 2001-12-17 2006-04-19 Bristol-Myers Squibb Company Transfer device and system comprising a cap assembly, a container and the transfer device
US6651956B2 (en) 2002-01-31 2003-11-25 Halkey-Roberts Corporation Slit-type swabable valve
US6875205B2 (en) 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
FR2836129B1 (fr) 2002-02-20 2004-04-02 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
AU2003201335B2 (en) 2002-03-20 2009-07-23 Becton, Dickinson And Company Shieldable needle assembly with biased safety shield
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US9440046B2 (en) 2002-04-04 2016-09-13 Angiodynamics, Inc. Venous insufficiency treatment method
US7744581B2 (en) 2002-04-08 2010-06-29 Carmel Pharma Ab Device and method for mixing medical fluids
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US6740277B2 (en) 2002-04-24 2004-05-25 Becton Dickinson And Company Process of making a catheter
USD472316S1 (en) 2002-04-30 2003-03-25 Sterling Medivations, Inc. Pen needle catheter connector
USD472630S1 (en) 2002-04-30 2003-04-01 Sterling Medivations, Inc. Pen needle catheter connector
US6914212B2 (en) 2002-05-01 2005-07-05 Becton Dickinson And Company Method of making a needle and a needle
USD476733S1 (en) 2002-05-09 2003-07-01 Becton, Dickinson And Company Medical needle assembly
EP1511528A4 (en) 2002-05-16 2008-07-02 Scott Lab Inc MECHANISMS FOR PENETRATION IN A MEDICINAL CONTAINER, AND ASSOCIATED METHOD
US20030236543A1 (en) 2002-06-25 2003-12-25 Brenneman Allen J. Polygonal cross section lancet needle
JP4427965B2 (ja) 2002-07-02 2010-03-10 ニプロ株式会社 連通手段付き薬液容器
SE523001C2 (sv) 2002-07-09 2004-03-23 Carmel Pharma Ab En kopplingsdel, en koppling, en infusionspåse, en infusionsanordning och ett förfarande för överföring av medicinska substanser
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
JP4209642B2 (ja) 2002-07-26 2009-01-14 川澄化学工業株式会社 針カバー及びキャップ付針カバー並びに針カバー付翼付針
US7326188B1 (en) 2002-08-02 2008-02-05 Elcam Medical Anesthesia manifold and induction valve
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
JP2004097253A (ja) 2002-09-04 2004-04-02 Nipro Corp 液体移注具
USD482121S1 (en) 2002-09-17 2003-11-11 Becton Dickinson And Company Needleless luer access port
USD482447S1 (en) 2002-09-17 2003-11-18 Becton Dickinson And Company Needleless luer access port
US6979318B1 (en) 2002-10-07 2005-12-27 Lemaitre Vascular, Inc. Catheter introducer
US20040073189A1 (en) 2002-10-09 2004-04-15 Phil Wyatt Vial access transfer set
US7544191B2 (en) 2002-10-22 2009-06-09 Baxter International Inc. Formed, filled, sealed solution container, port and method for establishing flow between the container and an administration set
USD483869S1 (en) 2002-10-29 2003-12-16 Pre Holding, Inc. Tubing connector
CA2505104A1 (en) 2002-11-08 2004-05-21 Duoject Medical Systems Inc. Pharmaceutical delivery systems and methods for using same
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
CH696186A5 (de) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Vorrichtung zur Sicherung von Injektionsnadeln.
CA103134S (en) 2002-11-26 2004-08-11 Nipro Corp Adapter for transfer of medical solution
US7086431B2 (en) 2002-12-09 2006-08-08 D'antonio Consultants International, Inc. Injection cartridge filling apparatus
USD483487S1 (en) 2002-12-19 2003-12-09 Becton Dickinson And Company Stopcock device
JP4341239B2 (ja) 2002-12-19 2009-10-07 ニプロ株式会社 液体移注具
US7125396B2 (en) 2002-12-30 2006-10-24 Cardinal Health 303, Inc. Safety catheter system and method
US7140592B2 (en) 2002-12-31 2006-11-28 Cardinal Health 303, Inc. Self-sealing male Luer connector with biased valve plug
US20040143226A1 (en) 2003-01-16 2004-07-22 Becton, Dickinson And Company Blood collection set with venting mechanism
US20040143218A1 (en) 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
US7678333B2 (en) 2003-01-22 2010-03-16 Duoject Medical Systems Inc. Fluid transfer assembly for pharmaceutical delivery system and method for using same
US7229419B2 (en) 2003-02-11 2007-06-12 Promex/U.S. Biosy Llc Single-handed biopsy system
US20040162540A1 (en) 2003-02-13 2004-08-19 Becton, Dickinson And Company Transfer device
EP1454609B1 (de) 2003-03-05 2012-10-24 CSL Behring GmbH Transfervorrichtung
EP1454650B1 (de) 2003-03-06 2007-10-10 CSL Behring GmbH Transfervorrichtung, insbesondere für medizinische Fluids
US20040181192A1 (en) 2003-03-11 2004-09-16 Cuppy Michael John Vascular access device and method of using same
US7470262B2 (en) 2003-03-17 2008-12-30 Nipro Corporation Medical valve
US7470265B2 (en) 2003-03-20 2008-12-30 Nxstage Medical, Inc. Dual access spike for infusate bags
US7024968B2 (en) 2003-03-26 2006-04-11 Boston Scientific Scimed, Inc. Luer lock wrench
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
WO2004096113A2 (en) 2003-04-28 2004-11-11 Medical Instill Technologies, Inc. Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
US7040598B2 (en) 2003-05-14 2006-05-09 Cardinal Health 303, Inc. Self-sealing male connector
USD495416S1 (en) 2003-05-30 2004-08-31 Alaris Medical Systems, Inc. Vial access device
US20040249235A1 (en) 2003-06-03 2004-12-09 Connell Edward G. Hazardous material handling system and method
US6948522B2 (en) 2003-06-06 2005-09-27 Baxter International Inc. Reconstitution device and method of use
CA2529429C (en) 2003-06-17 2009-10-20 Filtertek Inc. Fluid handling device and method of making same
FR2856660A1 (fr) 2003-06-30 2004-12-31 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
ITMO20030204A1 (it) 2003-07-14 2005-01-15 Gambro Lundia Ab Sacca per dialisi, set per dialisi comprendente detta
JP3883527B2 (ja) 2003-07-17 2007-02-21 ニプロ株式会社 トランスファーニードル
US7488297B2 (en) 2003-07-30 2009-02-10 Patrice Flaherty Blood collecting devices
US6960164B2 (en) 2003-08-01 2005-11-01 Neosurg Technologies, Inc. Obturator tip for a trocar
CN100509069C (zh) 2003-08-12 2009-07-08 贝克顿·迪金森公司 片状输液装置
EP2609946B1 (en) 2003-08-12 2018-05-16 Becton, Dickinson and Company Patch-like infusion device with shielding member
FR2858931B1 (fr) 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
US7097637B2 (en) 2003-08-27 2006-08-29 C. R. Bard, Inc. Safety needle with positive flush
US20050082828A1 (en) 2003-09-12 2005-04-21 Wicks Jeffrey C. Releasable connection assembly for joining tubing sections
US8122923B2 (en) 2003-10-30 2012-02-28 Teva Medical Ltd. Safety drug handling device
FR2863161B1 (fr) 2003-12-05 2006-09-01 Map France Capuchon pour conditionnement de securite pour flacon a usage medical
WO2005058744A2 (en) 2003-12-11 2005-06-30 Gregory Lambrecht Wine extraction and preservation device and method
US20080009822A1 (en) 2003-12-18 2008-01-10 Halkey-Roberts Corporation Needleless access vial
EP1699506A2 (en) 2003-12-18 2006-09-13 Halkey-Roberts Corporation Needleless access vial
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
US8454573B2 (en) 2008-05-06 2013-06-04 Philip Wyatt Medicament administration apparatus
US6997916B2 (en) 2004-01-02 2006-02-14 Smiths Medical Asd, Inc. Fluid transfer holder assembly and a method of fluid transfer
US7530546B2 (en) 2004-01-13 2009-05-12 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with zero fluid displacement
US6994315B2 (en) 2004-01-13 2006-02-07 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with neutral fluid displacement
US20050159706A1 (en) 2004-01-20 2005-07-21 Becton, Dickinson And Company Medical syringe with safety shield system
DE102004005435B3 (de) 2004-02-04 2005-09-15 Haindl, Hans, Dr. Medizinisches Transfergerät
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
ATE540721T1 (de) 2004-03-26 2012-01-15 Cook Medical Technologies Llc Verfahren und gerät für eine verbesserte luer- verbindung
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
DE102004021670A1 (de) 2004-05-03 2005-12-01 Saint-Gobain Calmar Gmbh Manuell betätigbarer Spender mit Schutzkappe
FR2869795B1 (fr) 2004-05-07 2006-08-04 Sedat Sa Dispositif de transfert bidirectionnel
US20050261637A1 (en) 2004-05-21 2005-11-24 Halkey-Roberts Corporation T-port with swabbable valve
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
DE102004036051A1 (de) 2004-07-24 2006-02-16 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Spritze
US7615041B2 (en) 2004-07-29 2009-11-10 Boston Scientific Scimed, Inc. Vial adaptor
DE202004012714U1 (de) 2004-08-12 2004-11-04 Smiths Medical Deutschland Gmbh Luer-Lock-Verbinder für medizinische Geräte
DE102004039408A1 (de) 2004-08-13 2006-03-02 Disetronic Licensing Ag Insertionskopf für medizinische oder pharmazeutische Anwendungen
JP2006061421A (ja) 2004-08-26 2006-03-09 Bio Media Co Ltd 薬剤収容ユニット
WO2006025054A2 (en) 2004-09-03 2006-03-09 Elcam Medical Agricultural Cooperative Association Ltd. Closed stopcock
US20060161192A1 (en) 2004-09-03 2006-07-20 Young Christopher S Wound needle with composite cutting edge
EP1800227A2 (en) 2004-10-04 2007-06-27 Clearpace Software Limited Method and system for implementing an enhanced database
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
JP4821947B2 (ja) 2004-10-19 2011-11-24 朝日インテック株式会社 薬液注入装置
US7771383B2 (en) 2004-10-22 2010-08-10 Medegen, Inc. Fluid control device with valve and methods of use
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US7192423B2 (en) 2004-11-17 2007-03-20 Cindy Wong Dispensing spike assembly with removable indicia bands
US8826988B2 (en) 2004-11-23 2014-09-09 Weatherford/Lamb, Inc. Latch position indicator system and method
US7241285B1 (en) 2004-12-06 2007-07-10 Medical Ventures, Inc. Medical site connection
FR2878737B1 (fr) 2004-12-07 2007-03-16 Maptech Soc Par Actions Simpli Dispositif de securite pour flacon a usage medical
US7645274B2 (en) 2004-12-10 2010-01-12 Cardinal Health 303, Inc. Self-sealing male luer connector with multiple seats
US7523967B2 (en) 2004-12-13 2009-04-28 Alcon, Inc. Tubing fitting
US20060135948A1 (en) 2004-12-16 2006-06-22 Medtronic Vascular, Inc., A Delaware Corporation Multi-exchange catheter guide member with improved seal
US7935070B2 (en) 2005-01-28 2011-05-03 Fresenius Medical Care North America Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product
US7704229B2 (en) 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
US7651482B2 (en) 2005-02-04 2010-01-26 Boston Scientific Scimed, Inc. Non-coring needles and methods of manufacturing same
DE602006017334D1 (de) 2005-02-14 2010-11-18 Medimop Medical Projects Ltd Medizinische vorrichtung für die rekonstitution eines flüssigen arzneimittels in situ in medizinischen gefässen
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US7666172B2 (en) 2005-03-15 2010-02-23 Plaridel Cerna Atil Medical needle having a closed tip
US20060253084A1 (en) 2005-05-03 2006-11-09 Greg Nordgren Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods
WO2006124756A2 (en) 2005-05-13 2006-11-23 Bob Rogers Medical substance transfer system
CA111438S (fr) 2005-05-23 2006-12-22 Rexam Dispensing Sys Pulvérisateur nasal
US20070088293A1 (en) 2005-07-06 2007-04-19 Fangrow Thomas F Jr Medical connector with closeable male luer
JP2007024928A (ja) 2005-07-12 2007-02-01 Nidec Sankyo Corp 光ビーム出射装置および画像形成装置
WO2007015233A1 (en) 2005-08-01 2007-02-08 Medimop Medical Projects Ltd Liquid drug delivery system
ES2371557T3 (es) 2005-08-11 2012-01-05 Medimop Medical Projects Ltd. Dispositivos de transferencia de fármacos líquidos para un correcto ajuste a presión a prueba de fallos en viales medicinales.
DE502005009907D1 (de) 2005-09-15 2010-08-26 Roche Diagnostics Gmbh Insertionskopf mit Griff
DK1764125T5 (da) 2005-09-15 2011-11-14 Hoffmann La Roche System bestående af indsættelseshoved og indsættelsesapparat
US8409142B2 (en) 2005-09-26 2013-04-02 Asante Solutions, Inc. Operating an infusion pump system
EP1948112A4 (en) 2005-10-11 2011-04-13 Podaima Blake SMART MEDICAL COMPLIANCE PROCESS AND SYSTEM
US7882863B2 (en) 2005-10-19 2011-02-08 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
CN101299983B (zh) 2005-10-30 2012-01-11 麦迪麦珀医疗工程有限公司 无针式附加剂控制阀
US7935104B2 (en) 2005-11-07 2011-05-03 Medingo, Ltd. Systems and methods for sustained medical infusion and devices related thereto
EP1951344B1 (en) 2005-11-07 2014-05-28 Industrie Borla SpA Vented safe handling vial adapter
DE102005055326A1 (de) 2005-11-11 2007-05-16 Storz Karl Gmbh & Co Kg Anschluss für ein medizinisches Saug- oder Spülinstrument
GB0523638D0 (en) 2005-11-21 2005-12-28 Cambridge Biostability Ltd Pharmaceutical device for the administration of substances to patients
JP2007143813A (ja) 2005-11-28 2007-06-14 Nippon Sherwood Medical Industries Ltd 医療用活栓
US20070191767A1 (en) 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
ATE447923T1 (de) 2006-02-16 2009-11-15 Hoffmann La Roche System und vorrichtung zum entnehmen von pharmazeutika
JP2007222472A (ja) 2006-02-24 2007-09-06 Nipro Corp 薬剤微量投与具セット
WO2007101772A1 (en) 2006-03-07 2007-09-13 Novo Nordisk A/S A drug mixing device
EP1911432A1 (en) 2006-10-10 2008-04-16 Novo Nordisk A/S A mixing unit
EP3513708B1 (en) 2006-03-09 2022-12-28 Dexcom, Inc. Systems and methods for processing analyte sensor data
IL174352A0 (en) 2006-03-16 2006-08-20 Medimop Medical Projects Ltd Medical devices for use with carpules
JP4769103B2 (ja) 2006-03-17 2011-09-07 日本シャーウッド株式会社 コネクタ
FR2898812B1 (fr) 2006-03-24 2008-06-13 Technoflex Sa Connecteur luer, connecteur medical et set de transfert comportant un tel connecteur
US8162904B2 (en) 2006-03-29 2012-04-24 Terumo Kabushiki Kaisha Needle protector
JP4775638B2 (ja) 2006-03-31 2011-09-21 株式会社ジェイ・エム・エス 連通部材、およびそれを用いた医療用容器、並びに輸液調剤用具セット
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
US7731735B2 (en) 2006-04-28 2010-06-08 Warsaw Orthopedic, Inc. Open axle surgical implant
JP4820703B2 (ja) 2006-04-28 2011-11-24 日本シャーウッド株式会社 液体混注具
US9295790B2 (en) 2006-05-05 2016-03-29 Retractable Technologies, Inc. Syringe with recessed nose and protective guard for use with frontal attachments
JP4871019B2 (ja) 2006-05-15 2012-02-08 日本コヴィディエン株式会社 液体混注具
ES2608284T3 (es) 2006-05-25 2017-04-07 Bayer Healthcare Llc Dispositivo de reconstitución
RU2008152754A (ru) 2006-06-02 2010-07-20 Асахи Полислайдер Компани, Лимитед (Jp) Прокалывающая игла и ланцет, оснащенный такой иглой
WO2007148708A1 (ja) 2006-06-19 2007-12-27 Nipro Corporation 薬液調製用キット
JP2008005974A (ja) 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd ルアー固定フィッティング接続構造
BRPI0714879A2 (pt) 2006-07-21 2013-02-26 Polimoom Medical Packaging As dispositivo de conector e mÉtodo para mistura estÉril
USD561348S1 (en) 2006-08-17 2008-02-05 Medimop Medical Projects Ltd. Vial adapter
US7670326B2 (en) 2006-09-25 2010-03-02 Teva Medical Ltd.. Syringe adapter element in drug mixing system
DE102006049528A1 (de) 2006-09-28 2008-04-03 Robert Bosch Gmbh Vorrichtung und Verfahren zur Montage eines Nadelschutzes auf einen Spritzenkörper
USD580558S1 (en) 2006-09-29 2008-11-11 Fujifilm Corporation Cap of cartridge for component extraction
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
ATE506985T1 (de) 2006-10-25 2011-05-15 Icu Medical Inc Medizinischer verbinder
WO2008067506A1 (en) 2006-11-30 2008-06-05 Medi-Physics, Inc. Dual-lumen needle
EP2101711A1 (en) 2006-11-30 2009-09-23 Medi-Physics, Inc. Dual-lumen needle with an elongate notch opening
US7758082B2 (en) 2006-12-05 2010-07-20 Nxstage Medical, Inc. Fluid line connector safety device
US20080135051A1 (en) 2006-12-07 2008-06-12 George Lee Air Line Adapter Structure Of Suction Apparatus
US8002756B2 (en) 2006-12-08 2011-08-23 Becton, Dickinson And Company Method and apparatus for delivering a therapeutic substance through an injection port
US7900659B2 (en) 2006-12-19 2011-03-08 Carefusion 303, Inc. Pressure equalizing device for vial access
EP2155298A4 (en) 2006-12-21 2012-04-04 Ssb Technology Pty Ltd NEEDLE POINTE
US8057431B2 (en) 2006-12-21 2011-11-15 B. Braun Melsungen Ag Hinged cap for needle device
IL180565A0 (en) 2007-01-04 2007-06-03 Ilan Brand An improved stopcock for administering medicaments into the patient's body
US8523830B2 (en) 2007-01-16 2013-09-03 Catheter Connections Disinfecting caps for medical female luer connectors
GB2446778A (en) 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
US8038654B2 (en) 2007-02-26 2011-10-18 Becton, Dickinson And Company Syringe having a hinged needle shield
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
DE502007004715D1 (de) 2007-03-14 2010-09-23 Hoffmann La Roche Insertionsvorrichtung für einen Insertionskopf, insbesondere für ein Infusionsset
GB0705782D0 (en) 2007-03-26 2007-05-02 Novartis Ag Vial assemblies
IL182605A0 (en) 2007-04-17 2007-07-24 Medimop Medical Projects Ltd Fluid control device with manually depressed actuator
BRPI0810582A2 (pt) 2007-04-23 2015-10-27 Program For Appropriate Technology In Health métodos e dispositivos para injeção intradérmica
EP2606872B1 (en) 2007-04-23 2014-07-02 Equashield Medical Ltd Method and apparatus for contamination-free transfer of a hazardous drug
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
IL182922A0 (en) 2007-05-02 2007-09-20 Medimop Medical Projects Ltd Automatic liquid drug reconstitution apparatus
US20080306439A1 (en) 2007-06-08 2008-12-11 Nelson M Bud Devices for mixing and applying a fluid composition
USD588693S1 (en) 2007-06-12 2009-03-17 Nordson Corporation Liquid dispensing syringe
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
WO2009014955A2 (en) 2007-07-20 2009-01-29 Amylin Pharmaceuticals, Inc. Pen injection device and method of using same
US8241265B2 (en) 2007-08-01 2012-08-14 Hospira, Inc. Medicament admixing system
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
CA2704933A1 (en) 2007-08-21 2009-02-26 Yukon Medical, Llc Vial access and injection system
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
WO2009029010A1 (en) 2007-08-30 2009-03-05 Carmel Pharma Ab Device, sealing member and fluid container
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
WO2009038860A2 (en) 2007-09-18 2009-03-26 Medeq Llc Medicament mixing and injection apparatus
BRPI0822769A2 (pt) 2007-09-18 2015-06-30 Sabiedriba Ar Ierobezotu Atbildibu Sdmd Dispositivo de agulha de segurança
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
DE102007046951B3 (de) 2007-10-01 2009-02-26 B. Braun Melsungen Ag Vorrichtung zum Einführen eines Medikaments in einen Infusionsbehälter
USD616090S1 (en) 2007-10-29 2010-05-18 Daikyo Seiko, Ltd. Sealing device for medicine container or medical apparatus
US8870832B2 (en) 2007-11-08 2014-10-28 Elcam Medical A.C.A.L Ltd Vial adaptor and manufacturing method therefor
DE102007061346A1 (de) 2007-12-17 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Spike mit zwei Dornen
WO2009087572A1 (en) 2008-01-09 2009-07-16 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
US8287496B2 (en) 2008-01-17 2012-10-16 Custom Medical Applications, Inc. Flow elements for use with flexible spinal needles, needle assemblies and methods therefor
IL188975A0 (en) 2008-01-23 2008-11-03 Medimop Medical Projects Ltd Fluid control device with stopper
FR2927533B1 (fr) 2008-02-18 2011-02-11 P2A Medical Capuchon de transfert securise
JP5509097B2 (ja) 2008-02-18 2014-06-04 アイシーユー・メディカル・インコーポレーテッド バイアルアダプタ
DE102008002800A1 (de) 2008-03-10 2009-09-24 Süddeutsche Feinmechanik GmbH Mischvorrichtung
JP5685522B2 (ja) 2008-04-01 2015-03-18 ユーコン・メディカル，リミテッド・ライアビリティ・カンパニー 複式容器用流体移送装置
US20090267011A1 (en) 2008-04-23 2009-10-29 Jason Hatton Dispensing valve assembly
FR2931363B1 (fr) 2008-05-23 2010-06-25 Vygon Connecteur pour circuit de liquide, notamment a usage medical et utilisation d'un tel connecteur
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US7967785B2 (en) 2008-07-14 2011-06-28 Nipro Healthcare Systems, Llc Insulin reservoir detection via magnetic switching
USD595862S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595863S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595421S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595420S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
GB0814747D0 (en) 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
US8480645B1 (en) 2008-08-22 2013-07-09 Sambhu N. Choudhury Multi-dose device for insertion into a vial and method of using the same
WO2010021749A2 (en) 2008-08-22 2010-02-25 Circle Biologics, Llc Fluid management devices and methods
DK2346551T3 (da) 2008-08-30 2021-03-01 Sanofi Aventis Deutschland Cylinderampul og kanylesystem til denne
JP5266990B2 (ja) 2008-09-10 2013-08-21 ニプロ株式会社 薬剤調製器具
US8523837B2 (en) 2008-10-14 2013-09-03 Mead Johnson Nutrition Company Nutritive substance delivery container
US7762524B2 (en) 2008-10-20 2010-07-27 Baxter International Inc. Barrier assembly for use with needleless connector
CA2780712A1 (en) 2008-11-12 2010-05-20 British Columbia Cancer Agency Branch Vial handling and injection safety systems and connectors
WO2010058806A1 (ja) 2008-11-21 2010-05-27 テルモ株式会社 接続具
CN102223866B (zh) 2008-11-25 2014-07-02 株式会社Jms 连接器
WO2010061742A1 (ja) 2008-11-25 2010-06-03 株式会社ジェイ・エム・エス コネクタ
US9370621B2 (en) 2008-12-16 2016-06-21 Medtronic Minimed, Inc. Needle insertion systems and methods
US20100160889A1 (en) 2008-12-22 2010-06-24 Baxter International Inc. Vial access spike assembly
EP2201968A1 (de) 2008-12-24 2010-06-30 Roche Diagnostics GmbH Insertionssystem und Insertionsvorrichtung
US8152779B2 (en) 2008-12-30 2012-04-10 Medimop Medical Projects Ltd. Needle assembly for drug pump
US8512309B2 (en) 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
US8221352B2 (en) 2009-01-29 2012-07-17 Michael Merchant Disposable safety needle system and safety enclosure means
AU2010210160B2 (en) 2009-02-05 2014-09-04 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
US8123736B2 (en) 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8012132B2 (en) 2009-02-24 2011-09-06 Becton, Dickinson And Company Luer-snap connection and luer-snap syringe
USD608900S1 (en) 2009-03-06 2010-01-26 Csp Technologies, Inc. Identification component for a vial
US8864725B2 (en) 2009-03-17 2014-10-21 Baxter Corporation Englewood Hazardous drug handling system, apparatus and method
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
USD634007S1 (en) 2009-03-31 2011-03-08 Medimop Medical Projects Ltd. Needleless additive control valve
US8182452B2 (en) 2009-04-06 2012-05-22 Carefusion 303, Inc. Closed male luer device for use with needleless access devices
US9345640B2 (en) 2009-04-14 2016-05-24 Yukon Medical, Llc Fluid transfer device
US7963939B2 (en) 2009-04-24 2011-06-21 Thomas Chun Syringe having extended blending path
US8308741B2 (en) 2009-04-28 2012-11-13 The Invention Science Fund I, Llc Systems and methods for automatically inserting a needle into a living subject
DE202009011019U1 (de) 2009-07-01 2010-12-02 Süddeutsche Feinmechanik GmbH Anordnung zum Entnehmen eines Mediums aus einem Fläschchen
CN102652843B (zh) 2009-07-01 2015-09-30 弗雷塞尼斯医疗保健控股公司 药物输送装置和相关系统以及方法
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
IL199767A0 (en) 2009-07-09 2010-04-15 Medimop Medical Projects Ltd Medical device for use with cartridge and vial
JP5333850B2 (ja) 2009-07-15 2013-11-06 ニプロ株式会社 連結器具
USD655071S1 (en) 2009-07-17 2012-03-06 Julia Graciela Davila Mariachi suit
USD627216S1 (en) 2009-07-21 2010-11-16 The United States Of America As Represented By The Director, National Security Agency Tamper cup seal
IL200547A (en) 2009-08-23 2014-06-30 Eli Shemesh A system for mixing drugs in many containers
US9149624B2 (en) 2009-09-02 2015-10-06 Carefusion 303, Inc. Disinfecting male luer connector caps
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
IL201323A0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
US9662271B2 (en) 2009-10-23 2017-05-30 Amgen Inc. Vial adapter and system
IL202070A0 (en) * 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
IL202069A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
DK2501356T3 (da) 2009-12-23 2014-04-28 Medimop Medical Projects Ltd Medicinsk apparatur og engangssæt omfattende strømningsstyrende indretning til anvendelse dermed til at rekonstituere og indgive en væskeformig medikamentdosering
US8998840B2 (en) 2009-12-30 2015-04-07 Medtronic Minimed, Inc. Connection and alignment systems and methods
US20130053814A1 (en) 2010-01-15 2013-02-28 Bayer Healthcare Llc Device
AU2011216997A1 (en) 2010-01-19 2012-08-02 Cambridge Enterprise Limited Apparatus and methods
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
EP2361599A1 (de) 2010-02-22 2011-08-31 Fresenius Kabi Deutschland GmbH Vorrichtung zum Zuführen oder Entnehmen einer Flüssigkeit in ein oder aus einem Behältnis
US8684994B2 (en) 2010-02-24 2014-04-01 Medimop Medical Projects Ltd. Fluid transfer assembly with venting arrangement
US8753325B2 (en) 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
US9381310B2 (en) 2010-03-10 2016-07-05 Terumo Kabushiki Kaisha Injection needle assembly and drug injection apparatus
US9980707B2 (en) 2011-04-04 2018-05-29 Cook Medical Technologies Llc Endoscopic ultrasound-guided biopsy needle
USD644104S1 (en) 2010-04-15 2011-08-30 Sumitomo Rubber Industries, Ltd. Rubber stopper for vial
US8702674B2 (en) 2010-04-27 2014-04-22 Crisi Medical Systems, Inc. Medication and identification information transfer apparatus
CN104984438B (zh) 2010-05-20 2018-08-10 贝克顿·迪金森公司 药物传送装置
EA032537B1 (ru) 2010-06-07 2019-06-28 Эмджен Инк. Способ работы устройства для доставки лекарственного средства
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
JP5888234B2 (ja) 2010-06-30 2016-03-16 ニプロ株式会社 噴霧器
WO2012004784A1 (en) 2010-07-04 2012-01-12 Medimop Medical Projects Ltd Vial adapter with syringe stabilizer
EP2591107A2 (en) 2010-07-06 2013-05-15 Aptateck Bio Ltd. Nucleic acid aptamer-based diagnostic methods with novel techniques for signal enhancement
US8721627B2 (en) 2010-07-22 2014-05-13 Carefusion 303, Inc. Needleless valve infection prevention and pre-opening device
USD654166S1 (en) 2010-08-06 2012-02-14 Neomed, Inc. Enteral connector
SI2923688T1 (sl) 2010-08-25 2017-07-31 Baxalta GmbH Sestav, ki omogoča uporabniku rekonstitucijo
US20120078214A1 (en) 2010-09-28 2012-03-29 Tyco Healthcare Group Lp Vial transfer needle assembly
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
IL209102A0 (en) 2010-11-04 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device with handle operated flow control member
IL209290A0 (en) 2010-11-14 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device having rotary flow control member
EP2462913A1 (en) 2010-12-10 2012-06-13 Fresenius Medical Care Deutschland GmbH Insert and vial for the infusion of liquids
JP5670242B2 (ja) 2011-03-29 2015-02-18 テルモ株式会社 薬剤調製用具
ES2675729T3 (es) 2011-04-12 2018-07-12 F. Hoffmann-La Roche Ag Dispositivo de conexión
US20120265163A1 (en) 2011-04-14 2012-10-18 Marc Bunjiun Cheng Coupling system to transfer material between containers
IL212420A0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
USD720067S1 (en) 2011-05-02 2014-12-23 Carmel Pharma Ab Medical device
WO2012150587A1 (en) 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Vial adaptor
FR2975896B1 (fr) 2011-06-06 2014-06-06 Biocorp Rech Et Dev Dispositif de connexion entre un recipient et un contenant, procede d'assemblage et d'utilisation d'un tel dispositif
US20140221940A1 (en) 2011-06-17 2014-08-07 Tau Tona Group LP Needle for delivery of dermal filler threads
USD673673S1 (en) 2011-07-11 2013-01-01 Hsien-Tsung Wang Transparent Y-type of intravenous drip infusion set
USD674084S1 (en) 2011-07-21 2013-01-08 Mtp Medical Technical Promotion Gmbh Puncture cannula
US20140194854A1 (en) 2011-08-29 2014-07-10 Sid Technologies Llc Subcutaneous and intradermal patch infusers
USD681230S1 (en) 2011-09-08 2013-04-30 Yukon Medical, Llc Shroud
IL215699A0 (en) 2011-10-11 2011-12-29 Medimop Medical Projects Ltd Liquid drug reconstitution assemblage for use with iv bag and drug vial
USD711516S1 (en) 2011-12-09 2014-08-19 John Guest International Limited Fluid connector
USD720452S1 (en) 2011-12-15 2014-12-30 Mark Jordan Syringe connection hub
AU344164S (en) 2012-02-02 2012-09-04 Terumo Corp Safety device for indwelling needle
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US20150013835A1 (en) 2012-02-29 2015-01-15 Sanofi-Aventis Deutschland Gmbh Extraction device for a single extraction of a medicament from a container
CN104159560B (zh) 2012-03-05 2017-04-26 贝克顿·迪金森公司 用于药物重构的带有浮动针的传递套件
US20130253448A1 (en) 2012-03-09 2013-09-26 Steven Baron Hypodermic Needle With Multiple Dispersement Openings
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
IL219065A0 (en) 2012-04-05 2012-07-31 Medimop Medical Projects Ltd Fluid transfer device with manual operated cartridge release arrangement
IL219222A0 (en) 2012-04-17 2012-07-31 Medimop Medical Projects Ltd Quick release vial adapter
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
JP5888606B2 (ja) 2012-06-18 2016-03-22 ニプロ株式会社 薬剤調製器具
IL221635A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Drug vial mixing and transfer device for use with iv bag and drug vial
IL221634A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Universal drug vial adapter
JP5868555B2 (ja) 2012-09-13 2016-02-24 メディモップ・メディカル・プロジェクツ・リミテッド 入れ子式雌薬瓶アダプタ
EP4234694A3 (en) 2012-11-21 2023-09-06 Amgen Inc. Drug delivery device
JP6113859B2 (ja) 2012-11-30 2017-04-12 ベクトン ディキンソン アンド カンパニー リミテッド 薬物移送組立体用の点滴アダプタ
USD717406S1 (en) 2012-12-10 2014-11-11 Enviro Water Solutions, Inc. Backwash fitting
EP2931207B1 (en) 2012-12-17 2017-05-10 Unitract Syringe Pty Ltd Vial adapter
USD714935S1 (en) 2013-01-10 2014-10-07 Fuso Pharmaeutical Industries, Ltd. Adapter for connecting a needle to a syringe
USD733291S1 (en) 2013-01-15 2015-06-30 Hsien-Tsung Wang Depressible plug for vial
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
USD732664S1 (en) 2013-02-25 2015-06-23 B. Braun Melsungen Ag Proximal catheter hub body
USD738494S1 (en) 2013-03-05 2015-09-08 Ikashmore Pty Ltd Blood collection safety device
USD733292S1 (en) 2013-03-10 2015-06-30 Rocomp Global, Llc Energy guide
US9308020B2 (en) 2013-03-14 2016-04-12 Cook Medical Technologies Llc Tri-fluted vascular access needle
USD720850S1 (en) 2013-03-15 2015-01-06 Sanovas, Inc. Catheter hub
USD733293S1 (en) 2013-03-15 2015-06-30 Rocomp Global, Llc Energy guide
IL225734A0 (en) 2013-04-14 2013-09-30 Medimop Medical Projects Ltd A ready-to-use medicine vial device including a medicine vial closure, and a medicine vial closure for it
GB201307385D0 (en) 2013-04-24 2013-06-05 Star Syringe Ltd Syringes
CN205626622U (zh) 2013-08-07 2016-10-12 麦迪麦珀医疗工程有限公司 与输液容器一起使用的液体转移装置
JP6446438B2 (ja) 2013-09-23 2018-12-26 ベクトン ディキンソン アンド カンパニー リミテッド 容器アクセス装置のための穿刺部材
AU353353S (en) 2013-10-02 2014-01-21 Terumo Corp Medical syringe
ES2722410T3 (es) 2013-11-06 2019-08-09 Becton Dickinson & Co Ltd Adaptador para dispositivo de acceso a viales
JP6829071B2 (ja) 2013-11-06 2021-02-10 ベクトン ディキンソン アンド カンパニー リミテッド ロッキング係合を有する医療コネクタ
US20150305770A1 (en) 2014-03-12 2015-10-29 Epicardial Frontiers, LLC System and method of image guided pericardial procedures including pericardioscopy, pericardial ablation, pericardial material delivery, pericardial tissue grasping and manipulation, pericardial lead placement, and pericardial surgical fastener placement
USD750235S1 (en) 2014-03-19 2016-02-23 ERBE-USA, Inc. Endoscope connector
USD794183S1 (en) 2014-03-19 2017-08-08 Medimop Medical Projects Ltd. Dual ended liquid transfer spike
EP3381431B1 (en) 2014-04-21 2023-03-29 Becton Dickinson and Company Limited Syringe adapter with compound motion disengagement
CN110368302B (zh) 2014-04-21 2023-03-10 贝克顿迪金森有限公司 与密闭式系统传送装置一起使用的隔膜器
WO2016023590A1 (de) * 2014-08-14 2016-02-18 Weibel Cds Ag Abgabevorrichtung mit wählbaren durchflussenkanälen und dichtung
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
JP6368603B2 (ja) 2014-09-25 2018-08-01 テルモ株式会社 消毒キャップ
EP4070830A1 (en) 2015-01-09 2022-10-12 Becton Dickinson and Company Limited Infusion adapter
WO2016205626A1 (en) 2015-06-18 2016-12-22 Neomed, Inc. Syringe-to-syringe male-male coupler
IL247376A0 (en) * 2016-08-21 2016-12-29 Medimop Medical Projects Ltd Injector assembly

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020096957A (ja) * 2016-08-21 2020-06-25 ウエスト・ファーマ．サービシーズ・イスラエル，リミテッド 注射器アセンブリ

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