JP2013537907A5 - - Google Patents

Info

Publication number

JP2013537907A5

JP2013537907A5 JP2013530217A JP2013530217A JP2013537907A5 JP 2013537907 A5 JP2013537907 A5 JP 2013537907A5 JP 2013530217 A JP2013530217 A JP 2013530217A JP 2013530217 A JP2013530217 A JP 2013530217A JP 2013537907 A5 JP2013537907 A5 JP 2013537907A5

Authority

JP

Japan

Prior art keywords

compound

optionally substituted

alkyl

pharmaceutically acceptable

acceptable salt

Prior art date

2011-09-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 150000001875 compounds Chemical class 0.000 claims 108
• 125000000217 alkyl group Chemical group 0.000 claims 43
• 150000003839 salts Chemical class 0.000 claims 43
• 229910052739 hydrogen Inorganic materials 0.000 claims 36
• 239000001257 hydrogen Substances 0.000 claims 36
• 150000002431 hydrogen Chemical class 0.000 claims 26
• 229910052736 halogen Inorganic materials 0.000 claims 16
• 150000002367 halogens Chemical class 0.000 claims 16
• 150000001540 azides Chemical class 0.000 claims 10
• 125000004093 cyano group Chemical group *C#N 0.000 claims 10
• 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 9
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 9
• 229940079593 drug Drugs 0.000 claims 9
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• 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 8
• 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 8
• -1 amino acid ester Chemical class 0.000 claims 8
• 125000003107 substituted aryl group Chemical group 0.000 claims 7
• 125000003118 aryl group Chemical group 0.000 claims 6
• 125000001072 heteroaryl group Chemical group 0.000 claims 5
• 125000000623 heterocyclic group Chemical group 0.000 claims 5
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• ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
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• YAAQYJCOIFNMKX-RSTNYOGXSA-N [(2r,3r,4r,5r)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-4-hydroxy-4-methyl-2-[[[[(2s)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-3-yl] 2-methylpropanoate Chemical compound O([P@@](=O)(OC[C@@H]1[C@H]([C@@](C)(O)[C@](C#N)(C=2N3N=CN=C(N)C3=CC=2)O1)OC(=O)C(C)C)N[C@@H](C)C(=O)OC(C)C)C1=CC=CC=C1 YAAQYJCOIFNMKX-RSTNYOGXSA-N 0.000 claims 1
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