|
EP0475255A3
(en)
*
|
1990-09-12 |
1993-04-14 |
F. Hoffmann-La Roche Ag |
Process for the preparation of optically pure (s)-alpha-((tert-butylsulfonyl)methyl)hydro cinnamic acid
|
|
CZ298749B6
(cs)
|
1996-10-18 |
2008-01-16 |
Vertex Pharmaceuticals Incorporated |
Inhibitory serinových proteáz a farmaceutické prostředky s jejich obsahem
|
|
EP1012180B1
(en)
|
1997-08-11 |
2004-12-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptide analogues
|
|
DE69829381T2
(de)
|
1997-08-11 |
2006-04-13 |
Boehringer Ingelheim (Canada) Ltd., Laval |
Hepatitis c inhibitor peptide
|
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
|
MXPA03000627A
(es)
|
2000-07-21 |
2004-07-30 |
Schering Corp |
Nuevos peptidos como inhibidores de proteasa serina-ns3 del virus de la hepatitis c.
|
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
CA2429359A1
(en)
|
2000-11-20 |
2002-08-08 |
Bristol-Myers Squibb Company |
Hepatitis c tripeptide inhibitors
|
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
WO2004032827A2
(en)
|
2002-05-20 |
2004-04-22 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
|
US20060199773A1
(en)
*
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
|
EP1506000B9
(en)
|
2002-05-20 |
2011-08-31 |
Bristol-Myers Squibb Company |
Heterocyclicsulfonamide hepatitis c virus inhibitors
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
US6878722B2
(en)
|
2002-05-20 |
2005-04-12 |
Bristol-Myers Squibb Company |
Substituted cycloalkyl P1′ hepatitis C virus inhibitors
|
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
US7601709B2
(en)
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
|
AU2004211637C1
(en)
|
2003-02-07 |
2010-08-19 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
|
EP1601685A1
(en)
|
2003-03-05 |
2005-12-07 |
Boehringer Ingelheim International GmbH |
Hepatitis c inhibiting compounds
|
|
JP4682140B2
(ja)
|
2003-03-05 |
2011-05-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類縁体
|
|
UA81028C2
(en)
|
2003-04-02 |
2007-11-26 |
Boehringer Ingelheim Int |
Pharmaceutical compositions for hepatitis c viral protease inhibitors
|
|
EP1629000B1
(en)
|
2003-04-16 |
2009-02-18 |
Bristol-Myers Squibb Company |
Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
|
|
SI1615613T1
(sl)
|
2003-04-18 |
2010-03-31 |
Enanta Pharm Inc |
Kinoksalinilni makrociklični inhibitorji serinske proteaze hepatitisa C
|
|
HRP20080014T3
(en)
|
2003-05-21 |
2008-02-29 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor compounds
|
|
WO2004113365A2
(en)
|
2003-06-05 |
2004-12-29 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c serine protease tri-peptide inhibitors
|
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
|
RS20060197A
(sr)
|
2003-09-22 |
2008-09-29 |
Boehringer Ingelheim International Gmbh., |
Makrociklični peptidi koji su aktivni protiv hepatitisa c virusa
|
|
CA2541634A1
(en)
|
2003-10-10 |
2005-04-28 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
TW201245229A
(en)
|
2003-10-14 |
2012-11-16 |
Hoffmann La Roche |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication
|
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
JP2007532479A
(ja)
|
2003-11-20 |
2007-11-15 |
シェーリング コーポレイション |
C型肝炎ウイルスns3プロテアーゼの脱ペプチド化インヒビター
|
|
ATE495185T1
(de)
|
2004-01-21 |
2011-01-15 |
Boehringer Ingelheim Int |
Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus
|
|
KR20120090077A
(ko)
|
2004-01-30 |
2012-08-16 |
얀센 알 앤드 디 아일랜드 |
Hcv ns?3 세린 프로테아제 저해제
|
|
AU2005228894B9
(en)
|
2004-03-30 |
2011-10-13 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
|
WO2006016930A2
(en)
|
2004-05-14 |
2006-02-16 |
Intermune, Inc. |
Methods for treating hcv infection
|
|
WO2005116054A1
(en)
|
2004-05-25 |
2005-12-08 |
Boehringer Ingelheim International, Gmbh |
Process for preparing acyclic hcv protease inhibitors
|
|
WO2006000085A1
(en)
|
2004-06-28 |
2006-01-05 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
|
DK1778702T3
(da)
|
2004-07-16 |
2011-10-17 |
Gilead Sciences Inc |
Antivirale forbindelser
|
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
JP4914355B2
(ja)
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
|
CA2577812A1
(en)
|
2004-08-27 |
2006-03-09 |
Schering Corporation |
Acylsulfonamide compounds as inhibitors of hepatitis c virus ns3 serine protease
|
|
EP1794178A1
(en)
|
2004-09-17 |
2007-06-13 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
|
WO2007001406A2
(en)
|
2004-10-05 |
2007-01-04 |
Chiron Corporation |
Aryl-containing macrocyclic compounds
|
|
EP1805187A1
(en)
|
2004-10-21 |
2007-07-11 |
Pfizer, Inc. |
Inhibitors of hepatitis c virus protease, and compositions and treatments using the same
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
NZ562167A
(en)
|
2005-03-08 |
2011-01-28 |
Boehringer Ingelheim Int |
Process for preparing macrocyclic compounds
|
|
WO2006119061A2
(en)
|
2005-05-02 |
2006-11-09 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
|
WO2006130686A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Hcv protease inhibitors in combination with food
|
|
US20060281689A1
(en)
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
|
WO2006130687A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis c virus protease inhibitor
|
|
US20060276404A1
(en)
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
US20060287248A1
(en)
|
2005-06-02 |
2006-12-21 |
Schering Corporation |
Asymmetric dosing methods
|
|
NZ563369A
(en)
|
2005-06-02 |
2011-03-31 |
Schering Corp |
Controlled-release formulation useful for treating disorders associated with hepatitus C virus
|
|
CN101212970B
(zh)
|
2005-06-02 |
2010-07-21 |
先灵公司 |
Hcv蛋白酶抑制剂与表面活性剂的组合物
|
|
US20060276406A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20070004635A1
(en)
|
2005-06-02 |
2007-01-04 |
Schering Corporation |
Method of treating interferon non-responders using HCV protease inhibitor
|
|
WO2006130554A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis c virus
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
TW200738742A
(en)
*
|
2005-07-14 |
2007-10-16 |
Gilead Sciences Inc |
Antiviral compounds
|
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
|
EP1910378B1
(en)
|
2005-07-20 |
2012-06-20 |
Boehringer Ingelheim International GmbH |
Hepatitis c inhibitor peptide analogs
|
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Hcv ns3蛋白酶抑制劑
|
|
JP5249028B2
(ja)
|
2005-07-25 |
2013-07-31 |
インターミューン・インコーポレーテッド |
C型肝炎ウイルス複製の新規大環状阻害剤
|
|
TWI412535B
(zh)
|
2005-07-29 |
2013-10-21 |
Tibotec Pharm Ltd |
C型肝炎病毒之大環抑制劑(五)
|
|
US7700552B2
(en)
|
2005-07-29 |
2010-04-20 |
Medivir Ab |
Macrocyclic inhibitors of hepatitis C virus
|
|
US20100120855A1
(en)
|
2005-07-29 |
2010-05-13 |
Tibotec Pharmaceuticals Ltd. |
Macrocylic inhibitors of hepatitis c virus
|
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
|
PL1919898T3
(pl)
|
2005-07-29 |
2011-06-30 |
Tibotec Pharm Ltd |
Makrocykliczne inhibitory wirusa zapalenia wątroby typu C
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
DK1919904T3
(da)
|
2005-07-29 |
2014-04-07 |
Janssen R & D Ireland |
Makrocykliske inhibitorer af hepatitis-c-virus
|
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
DK1919899T3
(da)
|
2005-07-29 |
2011-08-01 |
Tibotec Pharm Ltd |
Makrocykliske inhibitorer af hepatitis C virus
|
|
ES2373685T3
(es)
|
2005-07-29 |
2012-02-07 |
Tibotec Pharmaceuticals |
Inhibidores macrocíclicos del virus de la hepatitis c.
|
|
KR20080036598A
(ko)
|
2005-08-01 |
2008-04-28 |
머크 앤드 캄파니 인코포레이티드 |
Hcv ns3 프로테아제 억제제로서의 마크로사이클릭펩티드
|
|
EP1915382A2
(en)
|
2005-08-01 |
2008-04-30 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
GEP20104956B
(en)
|
2005-10-11 |
2010-04-12 |
Array Biopharma Inc |
Compounds for inhibiting hepatitis c viral replication and use thereof
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US20070161670A1
(en)
|
2006-01-09 |
2007-07-12 |
Bristol-Myers Squibb Company |
Process for the preparation of substituted heterocycles
|
|
MX2008011354A
(es)
|
2006-03-03 |
2008-09-15 |
Schering Corp |
Combinaciones farmaceuticas de inhibidores de proteasa del virus de hepatitis c y del sitio interno de entrada ribosomal del virus de hepatitis c.
|
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
|
US20070281884A1
(en)
|
2006-06-06 |
2007-12-06 |
Ying Sun |
Macrocyclic oximyl hepatitis C protease inhibitors
|
|
US7635683B2
(en)
*
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
|
US7582605B2
(en)
*
|
2006-08-11 |
2009-09-01 |
Enanta Pharmaceuticals, Inc. |
Phosphorus-containing hepatitis C serine protease inhibitors
|
|
US7605126B2
(en)
*
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
|
US20080107623A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|
|
US20080107625A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|