|
EP0475255A3
(en)
|
1990-09-12 |
1993-04-14 |
F. Hoffmann-La Roche Ag |
Process for the preparation of optically pure (s)-alpha-((tert-butylsulfonyl)methyl)hydro cinnamic acid
|
|
IN183120B
(enExample)
|
1996-10-18 |
1999-09-11 |
Vertex Pharma |
|
|
PT1012180E
(pt)
|
1997-08-11 |
2005-04-29 |
Boehringer Ingelheim Ca Ltd |
Analogos de peptidos inibidores da hepatite c
|
|
IL134232A0
(en)
|
1997-08-11 |
2001-04-30 |
Boehringer Ingelheim Ca Ltd |
Hepatitis c inhibitor peptides
|
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
|
MY139078A
(en)
|
2000-07-21 |
2009-08-28 |
Schering Corp |
Peptides as ns3-serine protease inhibitors of hepatitis c virus
|
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
|
CN100391967C
(zh)
|
2000-11-20 |
2008-06-04 |
布里斯托尔-迈尔斯斯奎布公司 |
丙型肝炎三肽抑制剂
|
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
WO2004043339A2
(en)
|
2002-05-20 |
2004-05-27 |
Bristol-Myers Squibb Company |
Substituted cycloalkyl p1' hepatitis c virus inhibitors
|
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
|
US20060199773A1
(en)
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
|
DE60336550D1
(de)
|
2002-05-20 |
2011-05-12 |
Bristol Myers Squibb Co |
Inhibitoren des hepatitis-c-virus
|
|
ATE481106T1
(de)
|
2002-05-20 |
2010-10-15 |
Bristol Myers Squibb Co |
Heterocyclische sulfonamid-hepatitis-c-virus- hemmer
|
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
US7601709B2
(en)
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
|
WO2004072243A2
(en)
|
2003-02-07 |
2004-08-26 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis c serine protease inhibitors
|
|
CA2516018C
(en)
|
2003-03-05 |
2011-08-23 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
|
WO2004101605A1
(en)
|
2003-03-05 |
2004-11-25 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibiting compounds
|
|
KR20050108420A
(ko)
|
2003-04-02 |
2005-11-16 |
베링거 인겔하임 인터내셔날 게엠베하 |
C형 간염 바이러스 프로테아제 억제제를 위한 약제학적조성물
|
|
JP4733023B2
(ja)
|
2003-04-16 |
2011-07-27 |
ブリストル−マイヤーズ スクイブ カンパニー |
C型肝炎ウイルスの大環状イソキノリンペプチド阻害剤
|
|
PL1615613T3
(pl)
|
2003-04-18 |
2010-04-30 |
Enanta Pharm Inc |
Chinoksalinylowe makrocykliczne inhibitory proteazy serynowej zapalenia wątroby typu C
|
|
AU2004240704B9
(en)
|
2003-05-21 |
2009-10-22 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor compounds
|
|
WO2004113365A2
(en)
|
2003-06-05 |
2004-12-29 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c serine protease tri-peptide inhibitors
|
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
|
US7642235B2
(en)
|
2003-09-22 |
2010-01-05 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
|
EP1692157B1
(en)
|
2003-10-10 |
2013-04-17 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
|
OA13315A
(en)
|
2003-10-14 |
2007-04-13 |
Intermune Inc |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication.
|
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
JP2007532479A
(ja)
|
2003-11-20 |
2007-11-15 |
シェーリング コーポレイション |
C型肝炎ウイルスns3プロテアーゼの脱ペプチド化インヒビター
|
|
CA2549851C
(en)
|
2004-01-21 |
2012-09-11 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis c virus
|
|
UA84050C2
(en)
|
2004-01-30 |
2008-09-10 |
Медивир Аб |
Hcv ns-3-serine protease inhibitors
|
|
JP4654239B2
(ja)
|
2004-03-15 |
2011-03-16 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎ウィルス感染症の治療に適した大環状ジペプチドの調製方法
|
|
EA012389B1
(ru)
|
2004-03-30 |
2009-10-30 |
Интермун, Инк. |
Макроциклические соединения в качестве ингибиторов вирусной репликации
|
|
WO2006016930A2
(en)
|
2004-05-14 |
2006-02-16 |
Intermune, Inc. |
Methods for treating hcv infection
|
|
US7514557B2
(en)
|
2004-05-25 |
2009-04-07 |
Boehringer Ingelheim International Gmbh |
Process for preparing acyclic HCV protease inhibitors
|
|
WO2006000085A1
(en)
|
2004-06-28 |
2006-01-05 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
|
CA2571984C
(en)
|
2004-07-16 |
2012-04-10 |
Gilead Sciences, Inc. |
Antiviral compounds
|
|
JP4914355B2
(ja)
|
2004-07-20 |
2012-04-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎インヒビターペプチド類似体
|
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
|
MX2007002371A
(es)
|
2004-08-27 |
2007-04-23 |
Schering Corp |
Compuestos de acilsulfonamida como inhibidores de la serina proteasa ns3 del virus de la hepatitis c.
|
|
WO2006033878A1
(en)
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International, Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
|
WO2007001406A2
(en)
|
2004-10-05 |
2007-01-04 |
Chiron Corporation |
Aryl-containing macrocyclic compounds
|
|
BRPI0517463A
(pt)
|
2004-10-21 |
2008-10-07 |
Pfizer |
inibidores da protease do vìrus da hepatite c, composições e tratamentos usando os mesmos
|
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
NZ562167A
(en)
|
2005-03-08 |
2011-01-28 |
Boehringer Ingelheim Int |
Process for preparing macrocyclic compounds
|
|
US7879797B2
(en)
|
2005-05-02 |
2011-02-01 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
WO2006130553A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Hcv protease inhibitors
|
|
US20060276407A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20060276406A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
|
US20060276404A1
(en)
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
|
EP1919478B1
(en)
|
2005-06-02 |
2016-03-23 |
Merck Sharp & Dohme Corp. |
Combination of hcv protease inhibitors with a surfactant
|
|
AU2006252623A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation useful for treating disorders associated with hepatitis C virus
|
|
US20070021351A1
(en)
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
|
US20060287248A1
(en)
|
2005-06-02 |
2006-12-21 |
Schering Corporation |
Asymmetric dosing methods
|
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
|
WO2006130626A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Method for modulating activity of hcv protease through use of a novel hcv protease inhibitor to reduce duration of treatment period
|
|
NZ563361A
(en)
|
2005-06-02 |
2011-02-25 |
Schering Corp |
HCV protease inhibitors in combination with food
|
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
TW200738742A
(en)
|
2005-07-14 |
2007-10-16 |
Gilead Sciences Inc |
Antiviral compounds
|
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
|
US20080200497A1
(en)
|
2005-07-20 |
2008-08-21 |
Bailey Murray D |
Hepatitis C Inhibitor Peptide Analogs
|
|
US7470664B2
(en)
|
2005-07-20 |
2008-12-30 |
Merck & Co., Inc. |
HCV NS3 protease inhibitors
|
|
BRPI0613962A2
(pt)
|
2005-07-25 |
2009-03-24 |
Intermune Inc |
inibidores macrocìclicos inovadores de replicação de vìrus da hepatite c
|
|
MY139923A
(en)
|
2005-07-29 |
2009-11-30 |
Tibotec Pharm Ltd |
Macrocylic inhibitors of hepatitis c virus
|
|
MY144607A
(en)
|
2005-07-29 |
2011-10-14 |
Tibotec Pharm Ltd |
Macrocylic inhibitors of hepatitis c virus
|
|
WO2007014924A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
|
WO2007017144A2
(en)
|
2005-07-29 |
2007-02-15 |
Medivir Ab |
Macrocylic inhibitors of hepatitis c virus
|
|
CA2617099C
(en)
|
2005-07-29 |
2014-03-25 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
|
DK1919904T3
(da)
|
2005-07-29 |
2014-04-07 |
Janssen R & D Ireland |
Makrocykliske inhibitorer af hepatitis-c-virus
|
|
CN101273042B
(zh)
|
2005-07-29 |
2013-11-06 |
泰博特克药品有限公司 |
丙型肝炎病毒的大环抑制剂
|
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
|
AU2006275605B2
(en)
|
2005-08-01 |
2011-01-06 |
Merck Sharp & Dohme Corp. |
Macrocyclic peptides as HCV NS3 protease inhibitors
|
|
US20090325889A1
(en)
|
2005-08-01 |
2009-12-31 |
David Alan Campbell |
Hepatitis c serine protease inhibitors and uses therefor
|
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
|
DK1999129T3
(da)
|
2005-10-11 |
2011-02-07 |
Intermune Inc |
Forbindelser og fremgangsmåder til inhibering af replikationen af hepatitis C-virus
|
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US8268776B2
(en)
|
2006-06-06 |
2012-09-18 |
Enanta Pharmaceuticals, Inc. |
Macrocylic oximyl hepatitis C protease inhibitors
|
|
US7635683B2
(en)
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
|
US7605126B2
(en)
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
|
US7582605B2
(en)
*
|
2006-08-11 |
2009-09-01 |
Enanta Pharmaceuticals, Inc. |
Phosphorus-containing hepatitis C serine protease inhibitors
|
|
ES2444575T3
(es)
*
|
2006-10-27 |
2014-02-25 |
Merck Sharp & Dohme Corp. |
Inhibidores de la proteasa NS3 del VHC
|
|
US7888464B2
(en)
*
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US7763584B2
(en)
*
|
2006-11-16 |
2010-07-27 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
US20080279821A1
(en)
|
2007-04-26 |
2008-11-13 |
Deqiang Niu |
Arylpiperidinyl and arylpyrrolidinyl macrocyclic hepatitis c serine protease inhibitors
|
|
US7964560B2
(en)
*
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|