ATE495185T1 - Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus - Google Patents

Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus

Info

Publication number
ATE495185T1
ATE495185T1 AT05706397T AT05706397T ATE495185T1 AT E495185 T1 ATE495185 T1 AT E495185T1 AT 05706397 T AT05706397 T AT 05706397T AT 05706397 T AT05706397 T AT 05706397T AT E495185 T1 ATE495185 T1 AT E495185T1
Authority
AT
Austria
Prior art keywords
virus
active against
against hepatitis
macrocyclic peptides
peptides active
Prior art date
Application number
AT05706397T
Other languages
English (en)
Inventor
Montse Llinas-Brunet
Murray Bailey
Punit K Bhardwaj
Francois Bilodeau
Pasquale Forgione
Elise Ghiro
Nathalie Goudreau
Teddy Halmos
Jean Rancourt
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of ATE495185T1 publication Critical patent/ATE495185T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT05706397T 2004-01-21 2005-01-18 Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus ATE495185T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53786304P 2004-01-21 2004-01-21
PCT/CA2005/000055 WO2005070955A1 (en) 2004-01-21 2005-01-18 Macrocyclic peptides active against the hepatitis c virus

Publications (1)

Publication Number Publication Date
ATE495185T1 true ATE495185T1 (de) 2011-01-15

Family

ID=34807139

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05706397T ATE495185T1 (de) 2004-01-21 2005-01-18 Makrocyclische peptide mit wirkung gegen das hepatitis-c-virus

Country Status (12)

Country Link
US (2) US7749961B2 (de)
EP (1) EP1730167B1 (de)
JP (1) JP4682155B2 (de)
AR (1) AR047444A1 (de)
AT (1) ATE495185T1 (de)
CA (1) CA2549851C (de)
DE (1) DE602005025855D1 (de)
ES (1) ES2358333T3 (de)
PE (1) PE20050764A1 (de)
TW (1) TW200528094A (de)
UY (1) UY28722A1 (de)
WO (1) WO2005070955A1 (de)

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US7749961B2 (en) 2010-07-06
JP2007534662A (ja) 2007-11-29
CA2549851A1 (en) 2005-08-04
AR047444A1 (es) 2006-01-18
JP4682155B2 (ja) 2011-05-11
ES2358333T3 (es) 2011-05-09
WO2005070955A1 (en) 2005-08-04
PE20050764A1 (es) 2005-11-24
DE602005025855D1 (de) 2011-02-24
TW200528094A (en) 2005-09-01
EP1730167B1 (de) 2011-01-12
EP1730167A1 (de) 2006-12-13
US20090264346A1 (en) 2009-10-22
US20050192212A1 (en) 2005-09-01
CA2549851C (en) 2012-09-11
EP1730167A4 (de) 2008-04-09

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