EP0475255A3
(en)
*
|
1990-09-12 |
1993-04-14 |
F. Hoffmann-La Roche Ag |
Process for the preparation of optically pure (s)-alpha-((tert-butylsulfonyl)methyl)hydro cinnamic acid
|
MXPA05003026A
(es)
|
1996-10-18 |
2005-06-15 |
Vertex Pharma |
Inhibidores de proteasas de serina, particularmente proteasas ns3 del virus de hepatitis c.
|
AU757783B2
(en)
|
1997-08-11 |
2003-03-06 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis C inhibitor peptides
|
HUP0100100A3
(en)
|
1997-08-11 |
2001-12-28 |
Boehringer Ingelheim Ca Ltd |
Hepatitis c inhibitor peptide analogues, pharmaceutical compositions comprising thereof and their use
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
IL153670A0
(en)
|
2000-07-21 |
2003-07-06 |
Schering Corp |
Novel peptides as ns3-serine protease inhibitors of hepatitis c virus
|
BR0115447A
(pt)
|
2000-11-20 |
2005-10-18 |
Bristol Myers Squibb Co |
Inibidores de tripeptìdeo de hepatite c
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
PL211889B1
(pl)
|
2002-05-20 |
2012-07-31 |
Bristol Myers Squibb Co |
Pochodna heterocyklosulfonamidowa, kompozycja ją zawierająca oraz ich zastosowanie
|
EP1506172B1
(en)
|
2002-05-20 |
2011-03-30 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
JP4271148B2
(ja)
|
2002-05-20 |
2009-06-03 |
ブリストル−マイヤーズ スクイブ カンパニー |
置換シクロアルキルp1’c型肝炎ウイルスインヒビター
|
US20060199773A1
(en)
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
US7601709B2
(en)
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
KR100940619B1
(ko)
|
2003-02-07 |
2010-02-05 |
이난타 파마슈티칼스, 인코포레이티드 |
마크로사이클릭 씨형 간염 세린 단백효소 억제제
|
DE602004029866D1
(de)
|
2003-03-05 |
2010-12-16 |
Boehringer Ingelheim Pharma |
Peptidanaloga mit inhibitorischer wirkung auf hepatitis c
|
CA2516016C
(en)
|
2003-03-05 |
2012-05-29 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibiting compounds
|
JP2006522017A
(ja)
|
2003-04-02 |
2006-09-28 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎ウイルスプロテアーゼインヒビターのための医薬組成物
|
ATE422895T1
(de)
|
2003-04-16 |
2009-03-15 |
Bristol Myers Squibb Co |
Makrocyclische isochinolinpeptidinhibitoren des hepatitis-c-virus
|
DK1615613T3
(da)
|
2003-04-18 |
2010-03-22 |
Enanta Pharm Inc |
Quinoxalinyl-makrocykliske hepatitis C serin protease-inhibitorer
|
UY28323A1
(es)
|
2003-05-21 |
2004-12-31 |
Boehringer Ingelheim Int |
Compuestos inhibidores de la hepatitis c
|
WO2004113365A2
(en)
|
2003-06-05 |
2004-12-29 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c serine protease tri-peptide inhibitors
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
AU2004274051A1
(en)
|
2003-09-22 |
2005-03-31 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
MXPA06004006A
(es)
|
2003-10-10 |
2006-06-28 |
Vertex Pharma |
Inhibidores de serina proteasas, especialmente de ns3-ns4a proteasa del virus de la hepatitis c.
|
NZ546347A
(en)
|
2003-10-14 |
2009-11-27 |
Intermune Inc |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2005051980A1
(en)
|
2003-11-20 |
2005-06-09 |
Schering Corporation |
Depeptidized inhibitors of hepatitis c virus ns3 protease
|
EP1730167B1
(en)
|
2004-01-21 |
2011-01-12 |
Boehringer Ingelheim International GmbH |
Macrocyclic peptides active against the hepatitis c virus
|
ES2336009T3
(es)
|
2004-01-30 |
2010-04-07 |
Medivir Ab |
Inhibidores de la ns-3 serina proteasa del vhc.
|
AP2006003763A0
(en)
|
2004-03-30 |
2006-10-31 |
Intermune Inc |
Macrocyclic compounds as inhibitors of viral replication
|
WO2006016930A2
(en)
|
2004-05-14 |
2006-02-16 |
Intermune, Inc. |
Methods for treating hcv infection
|
JP5156374B2
(ja)
|
2004-05-25 |
2013-03-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
非環式hcvプロテアーゼインヒビターの調製方法
|
EP1763531A4
(en)
|
2004-06-28 |
2009-07-01 |
Boehringer Ingelheim Int |
ANALOGUE OF HEPATITIS-C INHIBITING PEPTIDES
|
CA2571984C
(en)
|
2004-07-16 |
2012-04-10 |
Gilead Sciences, Inc. |
Antiviral compounds
|
ES2366478T3
(es)
|
2004-07-20 |
2011-10-20 |
Boehringer Ingelheim International Gmbh |
Análogos peptídicos inhibidores de la hepatitis c.
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
CN101068828A
(zh)
|
2004-08-27 |
2007-11-07 |
先灵公司 |
用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的酰基磺酰胺化合物
|
WO2006033878A1
(en)
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International, Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
WO2007001406A2
(en)
|
2004-10-05 |
2007-01-04 |
Chiron Corporation |
Aryl-containing macrocyclic compounds
|
BRPI0517463A
(pt)
|
2004-10-21 |
2008-10-07 |
Pfizer |
inibidores da protease do vìrus da hepatite c, composições e tratamentos usando os mesmos
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
PL1863833T3
(pl)
|
2005-03-08 |
2014-03-31 |
Boehringer Ingelheim Int |
Sposób otrzymywania związków makrocyklicznych
|
CA2606195C
(en)
|
2005-05-02 |
2015-03-31 |
Merck And Co., Inc. |
Hcv ns3 protease inhibitors
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
KR20080021634A
(ko)
|
2005-06-02 |
2008-03-07 |
쉐링 코포레이션 |
약제학적 조성물 및 이를 사용한 치료 방법
|
EP1898941A2
(en)
|
2005-06-02 |
2008-03-19 |
Schering Corporation |
Controlled-release formulation useful for treating disorders associated with hepatitis c virus
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
US20060276407A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
US20060287248A1
(en)
|
2005-06-02 |
2006-12-21 |
Schering Corporation |
Asymmetric dosing methods
|
WO2006130626A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Method for modulating activity of hcv protease through use of a novel hcv protease inhibitor to reduce duration of treatment period
|
AU2006252519B2
(en)
|
2005-06-02 |
2012-08-30 |
Merck Sharp & Dohme Corp. |
HCV protease inhibitors in combination with food
|
WO2006130552A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis c virus
|
WO2006130666A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Medicaments and methods combining a hcv protease inhibitor and an akr competitor
|
US20070004635A1
(en)
|
2005-06-02 |
2007-01-04 |
Schering Corporation |
Method of treating interferon non-responders using HCV protease inhibitor
|
US20070021351A1
(en)
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
TW200738742A
(en)
|
2005-07-14 |
2007-10-16 |
Gilead Sciences Inc |
Antiviral compounds
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
AR057456A1
(es)
|
2005-07-20 |
2007-12-05 |
Merck & Co Inc |
Inhibidores de la proteasa ns3 del vhc
|
US20080200497A1
(en)
|
2005-07-20 |
2008-08-21 |
Bailey Murray D |
Hepatitis C Inhibitor Peptide Analogs
|
EP2103623A3
(en)
|
2005-07-25 |
2009-12-16 |
Intermune, Inc. |
Novel macrocyclic inhibitors of Hepatitis C virus replication
|
SI1912997T1
(sl)
|
2005-07-29 |
2012-02-29 |
Tibotec Pharm Ltd |
Makrociklični inhibitorji virusa hepatitis C
|
EP1910347A2
(en)
|
2005-07-29 |
2008-04-16 |
Medivir Ab |
Macrocylic inhibitors of hepatitis c virus
|
CN101273042B
(zh)
|
2005-07-29 |
2013-11-06 |
泰博特克药品有限公司 |
丙型肝炎病毒的大环抑制剂
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
BRPI0614638A2
(pt)
|
2005-07-29 |
2011-04-12 |
Tibotec Pharm Ltd |
compostos inibidores macrocìclicos do vìrus da hepatite c, uso dos mesmos, processo para a preparação dos mesmos, combinação e composição farmacêutica
|
EA014293B1
(ru)
|
2005-07-29 |
2010-10-29 |
Тиботек Фармасьютикалз Лтд. |
Макроциклические ингибиторы вируса гепатита с
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
ES2449540T3
(es)
|
2005-07-29 |
2014-03-20 |
Janssen R&D Ireland |
Inhibidores macrocíclicos del virus de la hepatitis C
|
KR101381176B1
(ko)
|
2005-07-29 |
2014-04-11 |
메디비르 아베 |
C형 간염 바이러스의 마크로사이클릭 억제제
|
EP1915382A2
(en)
|
2005-08-01 |
2008-04-30 |
Phenomix Corporation |
Hepatitis c serine protease inhibitors and uses therefor
|
CA2615896C
(en)
|
2005-08-01 |
2012-11-13 |
Merck & Co., Inc. |
Macrocyclic peptides as hcv ns3 protease inhibitors
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
GEP20104956B
(en)
|
2005-10-11 |
2010-04-12 |
Array Biopharma Inc |
Compounds for inhibiting hepatitis c viral replication and use thereof
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US20070161670A1
(en)
|
2006-01-09 |
2007-07-12 |
Bristol-Myers Squibb Company |
Process for the preparation of substituted heterocycles
|
MX2008011354A
(es)
|
2006-03-03 |
2008-09-15 |
Schering Corp |
Combinaciones farmaceuticas de inhibidores de proteasa del virus de hepatitis c y del sitio interno de entrada ribosomal del virus de hepatitis c.
|
GB0609492D0
(en)
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
US20070281884A1
(en)
|
2006-06-06 |
2007-12-06 |
Ying Sun |
Macrocyclic oximyl hepatitis C protease inhibitors
|
US7635683B2
(en)
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
US7582605B2
(en)
|
2006-08-11 |
2009-09-01 |
Enanta Pharmaceuticals, Inc. |
Phosphorus-containing hepatitis C serine protease inhibitors
|
US7605126B2
(en)
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
US20080107623A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|
US20080107625A1
(en)
*
|
2006-11-01 |
2008-05-08 |
Bristol-Myers Squibb Company |
Inhibitors of Hepatitis C Virus
|