NO20062267L - Hepatitt C virus inhibitorer - Google Patents

Hepatitt C virus inhibitorer

Info

Publication number
NO20062267L
NO20062267L NO20062267A NO20062267A NO20062267L NO 20062267 L NO20062267 L NO 20062267L NO 20062267 A NO20062267 A NO 20062267A NO 20062267 A NO20062267 A NO 20062267A NO 20062267 L NO20062267 L NO 20062267L
Authority
NO
Norway
Prior art keywords
hepatitis
virus inhibitors
compounds
virus
inhibitors
Prior art date
Application number
NO20062267A
Other languages
English (en)
Inventor
Piyasena Hewawasam
Nicholas A Meanwell
Fiona Mcphee
Jeffrey A Campbell
Paul Michael Scola
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20062267L publication Critical patent/NO20062267L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Forbindelser er beskrevet som har den generelle formel (I) hvor R1, R2, R3, R4, R', B, Y og X er beskrevet i beskrivelsen. Preparater omfattende forbindelsene og metoder for anvendelse av forbindelsene til å hemme HCV er også beskrevet.
NO20062267A 2003-11-12 2006-05-19 Hepatitt C virus inhibitorer NO20062267L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51912403P 2003-11-12 2003-11-12
PCT/US2004/038165 WO2005046712A1 (en) 2003-11-12 2004-11-12 Hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
NO20062267L true NO20062267L (no) 2006-08-04

Family

ID=34590359

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062267A NO20062267L (no) 2003-11-12 2006-05-19 Hepatitt C virus inhibitorer

Country Status (8)

Country Link
US (1) US7132504B2 (no)
EP (1) EP1687018B1 (no)
JP (1) JP4675331B2 (no)
AT (1) ATE542826T1 (no)
ES (1) ES2380934T3 (no)
IS (1) IS8448A (no)
NO (1) NO20062267L (no)
WO (1) WO2005046712A1 (no)

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ATE542826T1 (de) 2012-02-15
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EP1687018B1 (en) 2012-01-25

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