MX2013007698A - Inhibidores de serina proteasa de hepatitis c macrociclicos de fenantridina. - Google Patents

Inhibidores de serina proteasa de hepatitis c macrociclicos de fenantridina.

Info

Publication number
MX2013007698A
MX2013007698A MX2013007698A MX2013007698A MX2013007698A MX 2013007698 A MX2013007698 A MX 2013007698A MX 2013007698 A MX2013007698 A MX 2013007698A MX 2013007698 A MX2013007698 A MX 2013007698A MX 2013007698 A MX2013007698 A MX 2013007698A
Authority
MX
Mexico
Prior art keywords
phenanthridine
protease inhibitors
serine protease
present
hepatitis
Prior art date
Application number
MX2013007698A
Other languages
English (en)
Inventor
Keith F Mcdaniel
David J Grampovnik
Jason P Shanley
Yat Sun Or
Hui-Ju Chen
Brian Green
Timothy Middleton
Todd Hopkins
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46383854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013007698(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2013007698A publication Critical patent/MX2013007698A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

La presente invención se refiere a compuestos macrocíclicos novedosos y a métodos para tratar infección de hepatitis C en un sujeto que necesita de la terapia con dichos compuestos macrocíclicos. La presente invención se refiere además a composiciones farmacéuticas que comprenden los compuestos de la presente invención, o sales, ésteres o profármacos farmacéuticamente aceptables de los mismos, en combinación con un transportador o excipiente.
MX2013007698A 2010-12-30 2011-12-29 Inhibidores de serina proteasa de hepatitis c macrociclicos de fenantridina. MX2013007698A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061428488P 2010-12-30 2010-12-30
US201161449331P 2011-03-04 2011-03-04
PCT/US2011/067701 WO2012092411A2 (en) 2010-12-30 2011-12-29 Phenanthridine macrocyclic hepatitis c serine protease inhibitors

Publications (1)

Publication Number Publication Date
MX2013007698A true MX2013007698A (es) 2013-08-15

Family

ID=46383854

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013007698A MX2013007698A (es) 2010-12-30 2011-12-29 Inhibidores de serina proteasa de hepatitis c macrociclicos de fenantridina.

Country Status (18)

Country Link
US (1) US8951964B2 (es)
EP (1) EP2658858A4 (es)
JP (1) JP2014506255A (es)
KR (1) KR20140003521A (es)
CN (1) CN103380132B (es)
AU (1) AU2011352145A1 (es)
BR (1) BR112013016480A2 (es)
CA (1) CA2821340A1 (es)
CO (1) CO6771427A2 (es)
CR (1) CR20130341A (es)
EA (1) EA201390988A1 (es)
EC (1) ECSP13012791A (es)
GT (1) GT201300172A (es)
MX (1) MX2013007698A (es)
PE (1) PE20140039A1 (es)
SG (1) SG191759A1 (es)
WO (1) WO2012092411A2 (es)
ZA (1) ZA201304579B (es)

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