JP2013079244A5 - - Google Patents
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- JP2013079244A5 JP2013079244A5 JP2012255474A JP2012255474A JP2013079244A5 JP 2013079244 A5 JP2013079244 A5 JP 2013079244A5 JP 2012255474 A JP2012255474 A JP 2012255474A JP 2012255474 A JP2012255474 A JP 2012255474A JP 2013079244 A5 JP2013079244 A5 JP 2013079244A5
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- Prior art keywords
- disease
- pharmaceutical composition
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 27
- 201000010099 disease Diseases 0.000 claims 20
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 20
- 125000003275 alpha amino acid group Chemical group 0.000 claims 18
- 230000000694 effects Effects 0.000 claims 12
- 108090000624 Cathepsin L Proteins 0.000 claims 11
- 102000004172 Cathepsin L Human genes 0.000 claims 11
- 230000001627 detrimental effect Effects 0.000 claims 9
- 102100026534 Procathepsin L Human genes 0.000 claims 6
- 238000003367 kinetic assay Methods 0.000 claims 6
- 108010028075 procathepsin L Proteins 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 235000004279 alanine Nutrition 0.000 claims 4
- 125000003295 alanine group Chemical group N[C@@H](C)C(=O)* 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 4
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 3
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 3
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 2
- 229960002964 adalimumab Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 241000699802 Cricetulus griseus Species 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 208000019693 Lung disease Diseases 0.000 claims 1
- 206010029164 Nephrotic syndrome Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 208000006045 Spondylarthropathies Diseases 0.000 claims 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 206010047115 Vasculitis Diseases 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 201000004982 autoimmune uveitis Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 208000019069 chronic childhood arthritis Diseases 0.000 claims 1
- GLNDAGDHSLMOKX-UHFFFAOYSA-N coumarin 120 Chemical compound C1=C(N)C=CC2=C1OC(=O)C=C2C GLNDAGDHSLMOKX-UHFFFAOYSA-N 0.000 claims 1
- 229960000633 dextran sulfate Drugs 0.000 claims 1
- 208000016097 disease of metabolism Diseases 0.000 claims 1
- 208000019622 heart disease Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 201000002215 juvenile rheumatoid arthritis Diseases 0.000 claims 1
- 208000019423 liver disease Diseases 0.000 claims 1
- 230000003211 malignant effect Effects 0.000 claims 1
- 208000030159 metabolic disease Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 208000026721 nail disease Diseases 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 210000001672 ovary Anatomy 0.000 claims 1
- 239000005022 packaging material Substances 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 201000005671 spondyloarthropathy Diseases 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78972506P | 2006-04-05 | 2006-04-05 | |
| US60/789,725 | 2006-04-05 | ||
| US79041406P | 2006-04-06 | 2006-04-06 | |
| US60/790,414 | 2006-04-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009504272A Division JP2009532474A (ja) | 2006-04-05 | 2007-04-04 | 抗体精製 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015143625A Division JP5947427B2 (ja) | 2006-04-05 | 2015-07-21 | 抗体精製 |
| JP2015181443A Division JP5994004B2 (ja) | 2006-04-05 | 2015-09-15 | 抗体精製 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013079244A JP2013079244A (ja) | 2013-05-02 |
| JP2013079244A5 true JP2013079244A5 (enExample) | 2014-05-29 |
| JP5813618B2 JP5813618B2 (ja) | 2015-11-17 |
Family
ID=38581592
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009504272A Withdrawn JP2009532474A (ja) | 2006-04-05 | 2007-04-04 | 抗体精製 |
| JP2012255474A Active JP5813618B2 (ja) | 2006-04-05 | 2012-11-21 | 抗体精製 |
| JP2013252725A Active JP5997128B2 (ja) | 2006-04-05 | 2013-12-06 | 抗体精製 |
| JP2015143625A Active JP5947427B2 (ja) | 2006-04-05 | 2015-07-21 | 抗体精製 |
| JP2015181443A Active JP5994004B2 (ja) | 2006-04-05 | 2015-09-15 | 抗体精製 |
| JP2016163422A Active JP6367277B2 (ja) | 2006-04-05 | 2016-08-24 | 抗体精製 |
| JP2018126553A Pending JP2018172416A (ja) | 2006-04-05 | 2018-07-03 | 抗体精製 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009504272A Withdrawn JP2009532474A (ja) | 2006-04-05 | 2007-04-04 | 抗体精製 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013252725A Active JP5997128B2 (ja) | 2006-04-05 | 2013-12-06 | 抗体精製 |
| JP2015143625A Active JP5947427B2 (ja) | 2006-04-05 | 2015-07-21 | 抗体精製 |
| JP2015181443A Active JP5994004B2 (ja) | 2006-04-05 | 2015-09-15 | 抗体精製 |
| JP2016163422A Active JP6367277B2 (ja) | 2006-04-05 | 2016-08-24 | 抗体精製 |
| JP2018126553A Pending JP2018172416A (ja) | 2006-04-05 | 2018-07-03 | 抗体精製 |
Country Status (16)
| Country | Link |
|---|---|
| US (17) | US7863426B2 (enExample) |
| EP (4) | EP2738178A1 (enExample) |
| JP (7) | JP2009532474A (enExample) |
| KR (4) | KR20090005315A (enExample) |
| CN (4) | CN101454025B (enExample) |
| AU (1) | AU2007235484B2 (enExample) |
| BR (1) | BRPI0709726A2 (enExample) |
| CA (2) | CA2911000A1 (enExample) |
| IL (1) | IL194236A (enExample) |
| MX (1) | MX2008012896A (enExample) |
| NZ (4) | NZ611859A (enExample) |
| RU (2) | RU2466740C2 (enExample) |
| SG (2) | SG10201406358SA (enExample) |
| TW (2) | TW201333030A (enExample) |
| WO (1) | WO2007117490A2 (enExample) |
| ZA (1) | ZA200808372B (enExample) |
Families Citing this family (170)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6090382A (en) * | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
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| US20090280065A1 (en) * | 2006-04-10 | 2009-11-12 | Willian Mary K | Uses and Compositions for Treatment of Psoriasis |
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| MY150740A (en) * | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
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| GB0414054D0 (en) | 2004-06-23 | 2004-07-28 | Owen Mumford Ltd | Improvements relating to automatic injection devices |
| US20060083741A1 (en) * | 2004-10-08 | 2006-04-20 | Hoffman Rebecca S | Treatment of respiratory syncytial virus (RSV) infection |
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| US9605064B2 (en) * | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
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| US20100021451A1 (en) * | 2006-06-08 | 2010-01-28 | Wong Robert L | Uses and compositions for treatment of ankylosing spondylitis |
| US20080311043A1 (en) * | 2006-06-08 | 2008-12-18 | Hoffman Rebecca S | Uses and compositions for treatment of psoriatic arthritis |
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| TWI661833B (zh) | 2007-11-30 | 2019-06-11 | 百慕達商艾伯維生物技術有限責任公司 | 蛋白質調配物及製造其之方法 |
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| PT2708559T (pt) | 2008-04-11 | 2018-05-16 | Chugai Pharmaceutical Co Ltd | Molécula de ligação ao antigénio capaz de se ligar repetidamente a duas ou mais moléculas de antigénio |
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