SG10201508401TA - Processes for purification of proteins - Google Patents
Processes for purification of proteinsInfo
- Publication number
- SG10201508401TA SG10201508401TA SG10201508401TA SG10201508401TA SG10201508401TA SG 10201508401T A SG10201508401T A SG 10201508401TA SG 10201508401T A SG10201508401T A SG 10201508401TA SG 10201508401T A SG10201508401T A SG 10201508401TA SG 10201508401T A SG10201508401T A SG 10201508401TA
- Authority
- SG
- Singapore
- Prior art keywords
- proteins
- purification
- processes
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/12—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
- B01D15/125—Pre-filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/30—Partition chromatography
- B01D15/305—Hydrophilic interaction chromatography [HILIC]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3847—Multimodal interactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/12—Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39176210P | 2010-10-11 | 2010-10-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201508401TA true SG10201508401TA (en) | 2015-11-27 |
Family
ID=45938674
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201508401TA SG10201508401TA (en) | 2010-10-11 | 2011-10-11 | Processes for purification of proteins |
| SG2013026935A SG189872A1 (en) | 2010-10-11 | 2011-10-11 | Processes for purification of proteins |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013026935A SG189872A1 (en) | 2010-10-11 | 2011-10-11 | Processes for purification of proteins |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20120264920A1 (en) |
| EP (1) | EP2627425A4 (en) |
| JP (1) | JP6023715B2 (en) |
| KR (1) | KR20130142128A (en) |
| CN (1) | CN103379949B (en) |
| AU (2) | AU2011316730B2 (en) |
| BR (1) | BR112013008738B1 (en) |
| CA (1) | CA2813747A1 (en) |
| IL (1) | IL225650A0 (en) |
| MX (1) | MX344268B (en) |
| NZ (1) | NZ608943A (en) |
| RU (1) | RU2610667C2 (en) |
| SG (2) | SG10201508401TA (en) |
| TW (1) | TW201221641A (en) |
| WO (1) | WO2012051147A1 (en) |
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| ES2749457T3 (en) | 2012-01-27 | 2020-03-20 | Prothena Biosciences Ltd | Humanized antibodies that recognize alpha-synuclein |
| US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
| WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
| US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
| TW201348246A (en) * | 2012-05-21 | 2013-12-01 | Abbvie Inc | Novel purification of human, humanized, or chimeric antibodies using protein a affinity chromatography |
| US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
| JP6182210B2 (en) * | 2012-06-29 | 2017-08-16 | イー・エム・デイー・ミリポア・コーポレイシヨン | Method for virus inactivation during protein purification process |
| EP2682168A1 (en) * | 2012-07-02 | 2014-01-08 | Millipore Corporation | Purification of biological molecules |
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| US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
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| MY181081A (en) * | 2013-12-27 | 2020-12-17 | Chugai Pharmaceutical Co Ltd | Method for purifying antibody having low isoelectric point |
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| CN105017418B (en) * | 2014-03-27 | 2021-02-23 | 上海药明康德新药开发有限公司 | Monoclonal antibody purification process |
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| US10792618B2 (en) | 2018-06-19 | 2020-10-06 | Sartorius Stedim Biotech Gmbh | Particle separation and/or purification of a fluid |
| CN112996805A (en) | 2018-08-30 | 2021-06-18 | Hcw生物科技公司 | Multi-chain chimeric polypeptides and uses thereof |
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-
2011
- 2011-10-11 SG SG10201508401TA patent/SG10201508401TA/en unknown
- 2011-10-11 CA CA2813747A patent/CA2813747A1/en not_active Abandoned
- 2011-10-11 EP EP11833232.9A patent/EP2627425A4/en not_active Withdrawn
- 2011-10-11 RU RU2013120948A patent/RU2610667C2/en active
- 2011-10-11 US US13/270,443 patent/US20120264920A1/en not_active Abandoned
- 2011-10-11 WO PCT/US2011/055691 patent/WO2012051147A1/en active Application Filing
- 2011-10-11 CN CN201180059849.0A patent/CN103379949B/en active Active
- 2011-10-11 AU AU2011316730A patent/AU2011316730B2/en active Active
- 2011-10-11 SG SG2013026935A patent/SG189872A1/en unknown
- 2011-10-11 JP JP2013533926A patent/JP6023715B2/en active Active
- 2011-10-11 TW TW100136849A patent/TW201221641A/en unknown
- 2011-10-11 BR BR112013008738-2A patent/BR112013008738B1/en active IP Right Grant
- 2011-10-11 MX MX2013004091A patent/MX344268B/en active IP Right Grant
- 2011-10-11 KR KR1020137012135A patent/KR20130142128A/en not_active Application Discontinuation
- 2011-10-11 NZ NZ60894311A patent/NZ608943A/en unknown
-
2013
- 2013-04-09 IL IL225650A patent/IL225650A0/en unknown
-
2016
- 2016-03-09 AU AU2016201535A patent/AU2016201535A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120264920A1 (en) | 2012-10-18 |
| CN103379949A (en) | 2013-10-30 |
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| AU2011316730A1 (en) | 2013-05-02 |
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| RU2013120948A (en) | 2014-11-20 |
| JP2013539787A (en) | 2013-10-28 |
| JP6023715B2 (en) | 2016-11-09 |
| WO2012051147A1 (en) | 2012-04-19 |
| KR20130142128A (en) | 2013-12-27 |
| EP2627425A4 (en) | 2014-11-05 |
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