|
ATE399796T1
(de)
*
|
1999-04-09 |
2008-07-15 |
Univ Zuerich |
Verfahren zur stabilisierung von chimären immunoglobulinen oder immunoglobulinfragmenten und stabilisiertes anti-egp-2-scfv-fragment
|
|
US20030133939A1
(en)
*
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7754208B2
(en)
*
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
US7601351B1
(en)
|
2002-06-26 |
2009-10-13 |
Human Genome Sciences, Inc. |
Antibodies against protective antigen
|
|
CA2524124C
(en)
|
2003-04-30 |
2014-03-25 |
Uwe Zangemeister-Wittke |
Methods for treating cancer using an immunotoxin
|
|
CA2525251C
(en)
|
2003-05-09 |
2015-10-27 |
Duke University |
Cd20-specific antibodies and methods employing same
|
|
ATE555133T1
(de)
|
2003-11-13 |
2012-05-15 |
Hanmi Holdings Co Ltd |
Igg fc fragment für einen arzneimittelträger und verfahren zu dessen herstellung
|
|
US8110665B2
(en)
|
2003-11-13 |
2012-02-07 |
Hanmi Holdings Co., Ltd. |
Pharmaceutical composition comprising an immunoglobulin FC region as a carrier
|
|
BRPI0514259A
(pt)
*
|
2004-08-11 |
2008-06-03 |
Trubion Pharmaceuticals Inc |
proteìna de fusão de domìnio de ligação
|
|
ES2671893T3
(es)
|
2004-10-06 |
2018-06-11 |
Mayo Foundation For Medical Education And Research |
B7-H1 y PD-1 en el tratamiento del carcinoma de células renales
|
|
US8137907B2
(en)
|
2005-01-03 |
2012-03-20 |
Cold Spring Harbor Laboratory |
Orthotopic and genetically tractable non-human animal model for liver cancer and the uses thereof
|
|
CN101160528A
(zh)
|
2005-02-14 |
2008-04-09 |
惠氏公司 |
Il17-f在诊断和治疗气道炎症中的用途
|
|
CA2596509A1
(en)
*
|
2005-02-14 |
2006-08-24 |
Wyeth |
Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
|
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
|
WO2006119013A2
(en)
*
|
2005-04-29 |
2006-11-09 |
Wyeth |
Nogo receptor functional motifs and peptide mimetics related thereto and methods of using the same
|
|
WO2006122787A1
(en)
|
2005-05-18 |
2006-11-23 |
Ablynx Nv |
Serum albumin binding proteins
|
|
EP1896587A2
(en)
|
2005-05-31 |
2008-03-12 |
Cold Spring Harbor Laboratory |
METHODS FOR PRODUCING MICRORNAs
|
|
US20070020660A1
(en)
*
|
2005-06-06 |
2007-01-25 |
Burczynski Michael E |
Expression profiles of peripheral blood mononuclear cells for inflammatory bowel diseases
|
|
CN101355965A
(zh)
|
2005-06-08 |
2009-01-28 |
达纳-法伯癌症研究院 |
通过抑制程序性细胞死亡1(pd-1)途经治疗持续性感染和癌症的方法及组合物
|
|
US20070014776A1
(en)
*
|
2005-06-09 |
2007-01-18 |
Gimeno Ruth E |
Identification of adiponutrin-related proteins as esterases and methods of use for the same
|
|
DK1899378T3
(da)
|
2005-06-21 |
2010-02-01 |
Xoma Technology Ltd |
IL-1 beta-bindende antistoffer og fragmenter deraf
|
|
JP2009500412A
(ja)
*
|
2005-07-07 |
2009-01-08 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
癌の処置のための、抗ctla−4抗体とcpgモチーフ含有合成オリゴデオキシヌクレオチドとの組み合わせ治療
|
|
WO2007009069A2
(en)
*
|
2005-07-13 |
2007-01-18 |
Amgen Mountain View Inc. |
Heat lysis production of proteins
|
|
US20080279850A1
(en)
*
|
2005-07-25 |
2008-11-13 |
Trubion Pharmaceuticals, Inc. |
B-Cell Reduction Using CD37-Specific and CD20-Specific Binding Molecules
|
|
HRP20140338T1
(hr)
*
|
2005-07-25 |
2014-06-20 |
Emergent Product Development Seattle, Llc |
Smanjenje broja b-stanica upotrebom molekula koje se specifiäśno vežu na cd37 i cd20
|
|
JP2009502936A
(ja)
|
2005-07-25 |
2009-01-29 |
トルビオン ファーマシューティカルズ, インコーポレイテッド |
Cd20特異的結合分子の単一投与量
|
|
ES2534760T3
(es)
*
|
2005-08-19 |
2015-04-28 |
Wyeth Llc |
Anticuerpos antagonistas contra GDF-8 y sus usos en el tratamiento de ELA y otros trastornos asociados con GDF-8
|
|
US9062126B2
(en)
|
2005-09-16 |
2015-06-23 |
Raptor Pharmaceuticals Inc. |
Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
|
|
US10155816B2
(en)
*
|
2005-11-28 |
2018-12-18 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
|
TW200744634A
(en)
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
|
JP2009529915A
(ja)
|
2006-03-20 |
2009-08-27 |
ゾーマ テクノロジー リミテッド |
ガストリン物質に対して特異的なヒト抗体および方法
|
|
MX2008012023A
(es)
*
|
2006-03-21 |
2008-10-01 |
Wyeth Corp |
Metodos para prevenir y tratar enfermedades amiloidogenicas.
|
|
BRPI0710011A2
(pt)
*
|
2006-04-14 |
2011-08-02 |
Trubion Pharmaceuticals Inc |
proteìnas de ligação compreendendo articulação de imunoglobulina e regiões fc dotadas de funções efetoras fc alteradas
|
|
BRPI0709623A2
(pt)
*
|
2006-04-19 |
2011-07-19 |
Wyeth Corp |
polinucleotìdeo inibitório, molécula de dna isolado, célula hospedeira, microorganismo, animal transgênico não humano, planta transgênica, kit, e, método para regular de modo negativo a expressão de um transgene por uma célula hospedeira
|
|
MX2008013394A
(es)
*
|
2006-04-21 |
2008-10-31 |
Wyeth Corp |
Metodos para tamizado de alta emision de lineas celulares.
|
|
WO2007139972A2
(en)
*
|
2006-05-25 |
2007-12-06 |
Wyeth |
Expression of the cysteine protease legumain in vascular and inflammatory diseases
|
|
JP5189082B2
(ja)
*
|
2006-05-25 |
2013-04-24 |
バイエル・ファルマ・アクチェンゲゼルシャフト |
二量体分子複合体
|
|
WO2007146968A2
(en)
*
|
2006-06-12 |
2007-12-21 |
Trubion Pharmaceuticals, Inc. |
Single-chain multivalent binding proteins with effector function
|
|
AU2016231617B2
(en)
*
|
2006-06-12 |
2018-08-23 |
Aptevo Research And Development Llc |
Single-chain multivalent binding proteins with effector function
|
|
US20080027001A1
(en)
*
|
2006-07-07 |
2008-01-31 |
Andrew Wood |
Nogo receptor functional motifs, peptide mimetics, and mutated functional motifs related thereto, and methods of using the same
|
|
US20080038258A1
(en)
*
|
2006-07-21 |
2008-02-14 |
Amgen Inc. |
Polypeptides with Reduced Susceptibility to Oxidation and Methods of Making
|
|
GB0614780D0
(en)
|
2006-07-25 |
2006-09-06 |
Ucb Sa |
Biological products
|
|
EP2057193B1
(en)
|
2006-08-04 |
2013-12-18 |
Novartis AG |
Ephb3-specific antibody and uses thereof
|
|
AR062435A1
(es)
|
2006-08-18 |
2008-11-05 |
Xoma Technology Ltd |
Anticuerpo especifico prlr (receptor de prolactina) y sus usos
|
|
BRPI0715714A2
(pt)
*
|
2006-08-25 |
2014-03-11 |
Wyeth Corp |
Métodos para diminuir a frequência de emergência de uma infecção viral de hepatite c resistente ao tratamento, para atrasar a emergência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir o nível de resistência de uma infecção viral de hepatite c resistente ao tratamento, para diminuir a emergência de uma infecção viral de hepatite c resistente a hcv-796, para identificar um indivíduo com uma probabilidade diminuída de responder a uma terapia viral anti-hepatite c, para monitorar, diagnosticar ou prognosticar a infecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar o curso de tratamento de uma infecção viral de hepatite c em um paciente, para prognosticar o desenvolvimento de um ainfecção viral de hepatite c resistente ao tratamento em um paciente, para monitorar a infecção viral de hepatite c em um paciente e para diagnosticar o desenvolvimento de uma infecção viral de hepatite ao tratamento em um paciente
|
|
WO2008031020A2
(en)
*
|
2006-09-08 |
2008-03-13 |
Wyeth |
Arginine wash in protein purification using affinity chromatography
|
|
KR101456728B1
(ko)
|
2006-09-08 |
2014-10-31 |
메디뮨 엘엘씨 |
인간화 항-cd19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도
|
|
WO2008036899A2
(en)
*
|
2006-09-22 |
2008-03-27 |
Amgen Inc. |
Methods for removing viral contaminants during protein purification
|
|
EP2076287A2
(en)
*
|
2006-10-12 |
2009-07-08 |
Wyeth |
Methods and compositions with reduced opalescence
|
|
US7846434B2
(en)
|
2006-10-24 |
2010-12-07 |
Trubion Pharmaceuticals, Inc. |
Materials and methods for improved immunoglycoproteins
|
|
CA2663536A1
(en)
*
|
2006-10-24 |
2008-05-02 |
Trubion Pharmaceuticals, Inc. |
Materials and methods for improved immunoglycoproteins
|
|
KR101519672B1
(ko)
|
2006-12-07 |
2015-05-29 |
노파르티스 아게 |
Ephb3에 대한 길항제 항체
|
|
EP2102244A2
(en)
|
2006-12-19 |
2009-09-23 |
Ablynx N.V. |
Amino acid sequences directed against a metalloproteinase from the adam family and polypeptides comprising the same for the treatment of adam-related diseases and disorders
|
|
WO2008074839A2
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
|
|
CA2673592C
(en)
|
2006-12-20 |
2014-03-25 |
Xoma Technology Ltd. |
Methods for the treatment of il-1.beta. related diseases
|
|
CN103536915A
(zh)
*
|
2006-12-27 |
2014-01-29 |
埃默里大学 |
用于治疗传染病和肿瘤的组合物和方法
|
|
TW201307390A
(zh)
*
|
2007-02-02 |
2013-02-16 |
Amgen Inc |
海帕西啶(hepcidin)、海帕西啶拮抗劑及使用方法
|
|
WO2008104803A2
(en)
|
2007-02-26 |
2008-09-04 |
Oxford Genome Sciences (Uk) Limited |
Proteins
|
|
CL2008000883A1
(es)
*
|
2007-03-28 |
2008-10-03 |
Wyeth6 3 |
Metodo de deteccion de compuestos capaces de antagonizar la senalizacion de il-17f/il-17a; compuesto identificado por dicho metodo; uso de una cantidad de un antagonista de senalizacion de il-17f/il-17a, composicion farmaceutica que comprende dicho a
|
|
TW200902708A
(en)
*
|
2007-04-23 |
2009-01-16 |
Wyeth Corp |
Methods of protein production using anti-senescence compounds
|
|
JP5837747B2
(ja)
*
|
2007-05-17 |
2015-12-24 |
ベーリンガー インゲルハイム エルツェーファウ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
組換えタンパク質を工業規模で製造する方法
|
|
US20090304590A1
(en)
*
|
2007-05-29 |
2009-12-10 |
Wyeth |
Therapeutic compositions and methods
|
|
US20090258005A1
(en)
*
|
2007-05-29 |
2009-10-15 |
Trubion Pharmaceuticals Inc. |
Therapeutic compositions and methods
|
|
CN105131127B
(zh)
*
|
2007-05-30 |
2018-09-07 |
浦项工科大学校产学协力团 |
免疫球蛋白融合蛋白
|
|
CA2689895A1
(en)
*
|
2007-05-31 |
2008-12-04 |
Genmab A/S |
Non-glycosylated recombinant monovalent antibodies
|
|
WO2009023562A2
(en)
*
|
2007-08-09 |
2009-02-19 |
Wyeth |
Use of perfusion to enhance production of fed-batch cell culture in bioreactors
|
|
PE20140196A1
(es)
|
2007-08-09 |
2014-03-19 |
Boehringer Ingelheim Int |
Anticuerpos anti-cd37
|
|
CA2697032C
(en)
|
2007-08-22 |
2021-09-14 |
The Regents Of The University Of California |
Activatable binding polypeptides and methods of identification and use thereof
|
|
WO2009032845A2
(en)
|
2007-09-04 |
2009-03-12 |
Compugen, Ltd. |
Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
|
|
EP2205280B1
(en)
*
|
2007-09-27 |
2019-09-04 |
Amgen Inc. |
Pharmaceutical formulations
|
|
AU2014250683B2
(en)
*
|
2007-11-01 |
2015-11-26 |
Astellas Pharma Inc. |
Immunosuppressive polypeptides and nucleic acids
|
|
AU2008319053B2
(en)
|
2007-11-01 |
2012-04-26 |
Astellas Pharma Inc. |
Immunosuppressive polypeptides and nucleic acids
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
EP2219602A1
(en)
|
2007-11-15 |
2010-08-25 |
Amgen, Inc |
Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration
|
|
US8637029B2
(en)
|
2007-12-20 |
2014-01-28 |
Xoma Technology Ltd. |
Methods for the treatment of gout
|
|
EP2231183A2
(en)
|
2007-12-21 |
2010-09-29 |
Genentech, Inc. |
Therapy of rituximab-refractory rheumatoid arthritis patients
|
|
WO2009085200A2
(en)
|
2007-12-21 |
2009-07-09 |
Amgen Inc. |
Anti-amyloid antibodies and uses thereof
|
|
ES2500066T3
(es)
|
2008-01-25 |
2014-09-30 |
Amgen, Inc |
Anticuerpos frente a ferroportina y métodos de uso
|
|
JP5889533B2
(ja)
|
2008-01-31 |
2016-03-22 |
ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
改変された抗体定常ドメイン分子
|
|
AU2014200215B2
(en)
*
|
2008-01-31 |
2016-09-29 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Engineered antibody constant domain molecules
|
|
EP2257634A1
(en)
*
|
2008-03-12 |
2010-12-08 |
Wyeth LLC |
Method for identifying cells suitable for large-scale production of recombinant proteins
|
|
AU2009235467A1
(en)
|
2008-04-07 |
2009-10-15 |
Ablynx Nv |
Single variable domains against the Notch pathways
|
|
EP2365003A1
(en)
|
2008-04-11 |
2011-09-14 |
Emergent Product Development Seattle, LLC |
CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
US20090269339A1
(en)
*
|
2008-04-29 |
2009-10-29 |
Genentech, Inc. |
Responses to immunizations in rheumatoid arthritis patients treated with a cd20 antibody
|
|
CA2722600C
(en)
|
2008-05-01 |
2014-01-21 |
Amgen Inc. |
Anti-hepcidin antibodies and methods of use
|
|
WO2010014629A1
(en)
*
|
2008-07-28 |
2010-02-04 |
Trubion Pharmaceuticals, Inc. |
Multi-specific binding proteins targeting b cell disorders
|
|
DK2329020T3
(da)
|
2008-08-28 |
2013-06-10 |
Novartis Ag |
Celleoverfladepræsentation af polypeptidisoformer ved hjælp af stopcodon-overspringelse
|
|
TW201014605A
(en)
|
2008-09-16 |
2010-04-16 |
Genentech Inc |
Methods for treating progressive multiple sclerosis
|
|
JP2012504939A
(ja)
|
2008-09-23 |
2012-03-01 |
ワイス・エルエルシー |
架橋結合タンパク質による活性化シグナルの産生を予測するための方法
|
|
EP2356231A2
(en)
*
|
2008-09-26 |
2011-08-17 |
Wyeth LLC |
Compatible display vector systems
|
|
JP2012503982A
(ja)
|
2008-09-26 |
2012-02-16 |
ワイス・エルエルシー |
適合性ディスプレイベクター系
|
|
NZ592420A
(en)
|
2008-10-02 |
2012-12-21 |
Emergent Product Dev Seattle |
Cd86 antagonist multi-target binding proteins
|
|
CN105218673A
(zh)
*
|
2008-10-10 |
2016-01-06 |
新兴产品开发西雅图有限公司 |
Tcr复合物免疫治疗剂
|
|
JP2012507565A
(ja)
|
2008-10-30 |
2012-03-29 |
グオ・ペイシュエン |
Dnaのシークエンシング及び他の用途のための、膜に組み込まれたウイルスdnaパッケージングモータタンパク質コネクタバイオセンサ
|
|
RU2526156C2
(ru)
*
|
2008-11-13 |
2014-08-20 |
ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ, ЭлЭлСи |
Cd37-иммунотерапевтическая комбинированная терапия и ее применения
|
|
KR20110097772A
(ko)
*
|
2008-11-17 |
2011-08-31 |
제넨테크, 인크. |
생리적 조건하에 거대분자의 응집을 감소시키는 방법 및 제제
|
|
CA2744449C
(en)
*
|
2008-11-28 |
2019-01-29 |
Emory University |
Methods for the treatment of infections and tumors
|
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
|
US20100189651A1
(en)
|
2009-01-12 |
2010-07-29 |
Cytomx Therapeutics, Llc |
Modified antibody compositions, methods of making and using thereof
|
|
JP5861223B2
(ja)
*
|
2009-02-23 |
2016-02-16 |
サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. |
プロタンパク質およびその使用方法
|
|
CN102395597A
(zh)
|
2009-03-11 |
2012-03-28 |
惠氏有限责任公司 |
纯化小模块免疫药物蛋白的方法
|
|
JP2010213694A
(ja)
|
2009-03-12 |
2010-09-30 |
Wyeth Llc |
PKN3/RhoC高分子複合体およびその使用方法
|
|
EP2408814B1
(en)
|
2009-03-20 |
2018-11-21 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
US9586180B2
(en)
|
2009-03-24 |
2017-03-07 |
Wyeth Llc |
Membrane evaporation for generating highly concentrated protein therapeutics
|
|
NZ595461A
(en)
|
2009-04-10 |
2013-01-25 |
Ablynx Nv |
Improved amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of il-6r related diseases and disorders
|
|
WO2010132697A2
(en)
*
|
2009-05-13 |
2010-11-18 |
Genzyme Corporation |
Methods and compositions for treatment
|
|
ES2643034T3
(es)
|
2009-06-05 |
2017-11-21 |
Ablynx N.V. |
Construcciones de Nanobody contra el virus respiratorio sincicial humano (VRSH) trivalentes para la prevención y/o el tratamiento de infecciones de las vías respiratorias
|
|
CA2766861A1
(en)
|
2009-07-09 |
2011-01-13 |
F. Hoffmann-La Roche Ag |
In vivo tumor vasculature imaging
|
|
US20120283415A1
(en)
*
|
2009-09-10 |
2012-11-08 |
Ucb Pharma S.A. |
Multivalent Antibodies
|
|
CN102597775A
(zh)
|
2009-09-25 |
2012-07-18 |
佐马技术有限公司 |
筛选方法
|
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
|
KR101934923B1
(ko)
|
2009-11-02 |
2019-04-10 |
유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 |
치료학적 뉴클레아제 조성물 및 방법
|
|
AU2010321832B2
(en)
|
2009-11-20 |
2014-08-14 |
Amgen Inc. |
Anti-Orai1 antigen binding proteins and uses thereof
|
|
DE102009047243A1
(de)
|
2009-11-27 |
2011-06-01 |
Orgentec Diagnostika Gmbh |
Monospezifische Polypeptidreagenzien
|
|
WO2011064382A1
(en)
|
2009-11-30 |
2011-06-03 |
Ablynx N.V. |
Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections
|
|
EP2513145B1
(en)
|
2009-12-14 |
2018-01-24 |
Ablynx N.V. |
Single variable domain antibodies against ox40l, constructs and therapeutic use
|
|
US8765432B2
(en)
|
2009-12-18 |
2014-07-01 |
Oligasis, Llc |
Targeted drug phosphorylcholine polymer conjugates
|
|
US20130052195A1
(en)
|
2009-12-23 |
2013-02-28 |
Emergent Product Development Seattle,LLC |
Compositions Comprising TNF-alpha and IL-6 Antagonists and Methods of Use Thereof
|
|
CN102958942A
(zh)
|
2009-12-29 |
2013-03-06 |
新兴产品开发西雅图有限公司 |
异二聚体结合蛋白及其应用
|
|
WO2011083141A2
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Method for generation of immunoglobulin sequences by using lipoprotein particles
|
|
US9120855B2
(en)
|
2010-02-10 |
2015-09-01 |
Novartis Ag |
Biologic compounds directed against death receptor 5
|
|
TW201129384A
(en)
|
2010-02-10 |
2011-09-01 |
Immunogen Inc |
CD20 antibodies and uses thereof
|
|
US9260529B2
(en)
*
|
2010-02-24 |
2016-02-16 |
The University Of Washington Through Its Center For Commercialization |
Molecules that bind CD180, compositions and methods of use
|
|
SG183542A1
(en)
*
|
2010-03-12 |
2012-10-30 |
Immunogen Inc |
Cd37-binding molecules and immunoconjugates thereof
|
|
CA2793778A1
(en)
|
2010-04-05 |
2011-11-13 |
Wyeth Llc |
Biomarkers for p13k-driven cancer
|
|
SMT202000095T1
(it)
|
2010-05-14 |
2020-03-13 |
Amgen Inc |
Formulazioni di anticorpi anti-sclerostina ad alta concentrazione
|
|
CN102906118B
(zh)
|
2010-05-20 |
2017-07-28 |
埃博灵克斯股份有限公司 |
与her3相关的生物材料
|
|
CA2808116C
(en)
|
2010-07-30 |
2016-06-07 |
Pfizer Inc. |
Tandem purification of proteins
|
|
JP2013541501A
(ja)
|
2010-08-03 |
2013-11-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
慢性リンパ性白血病(cll)のバイオマーカー
|
|
SG187787A1
(en)
|
2010-08-10 |
2013-03-28 |
Amgen Inc |
Dual function in vitro target binding assay for the detection of neutralizing antibodies against target antibodies
|
|
SMT201700185T1
(it)
|
2010-08-23 |
2017-05-08 |
Univ Texas |
Anticorpi anti-ox40 e metodi di uso degli stessi
|
|
WO2012040518A2
(en)
|
2010-09-22 |
2012-03-29 |
Amgen Inc. |
Carrier immunoglobulins and uses thereof
|
|
EA202092589A3
(ru)
|
2010-11-08 |
2021-06-30 |
Аблинкс Н.В. |
Cxcr2-связывающие полипептиды
|
|
WO2012064733A2
(en)
*
|
2010-11-09 |
2012-05-18 |
Medimmune, Llc |
Antibody scaffold for homogenous conjugation
|
|
AR084020A1
(es)
|
2010-11-30 |
2013-04-17 |
Genentech Inc |
Anticuerpos para el receptor de la barrera hematoencefalica de baja afinidad y sus usos
|
|
KR101614997B1
(ko)
|
2011-01-10 |
2016-04-22 |
씨티 아틀란틱 엘티디. |
종양 관련 항원 결합 항체를 포함하는 조합 요법
|
|
CA2827170A1
(en)
|
2011-02-11 |
2012-08-16 |
David M. Hilbert |
Monovalent and multivalent multispecific complexes and uses thereof
|
|
EP2686418A4
(en)
|
2011-03-17 |
2015-04-22 |
Minerva Biotechnologies Corp |
METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS
|
|
EP2694105A4
(en)
|
2011-04-01 |
2015-04-29 |
Immunogen Inc |
CD37 BINDING MOLECULES AND IMMUNOCONJUGATES THEREOF
|
|
RS55609B1
(sr)
*
|
2011-04-13 |
2017-06-30 |
Bristol Myers Squibb Co |
Fc fuzioni proteini koji sadrže nove linkere ili aranžmane
|
|
UA118950C2
(uk)
|
2011-04-22 |
2019-04-10 |
Аптево Рісьорч Енд Девелопмент Ллс |
Поліпептид, який зв'язує специфічний мембранний антиген простати та комплекс т-клітинного рецептора
|
|
PH12013502441B1
(en)
|
2011-04-29 |
2019-02-08 |
Univ Washington |
Therapeutic nuclease compositions and methods
|
|
UA117218C2
(uk)
|
2011-05-05 |
2018-07-10 |
Мерк Патент Гмбх |
Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
|
|
EP2707021B1
(en)
*
|
2011-05-09 |
2024-02-21 |
Minerva Biotechnologies Corporation |
Genetically engineered growth factor variants
|
|
US20140186363A1
(en)
|
2011-06-03 |
2014-07-03 |
University Of Zurich |
Magea3 binding antibodies
|
|
WO2012163771A1
(en)
|
2011-06-03 |
2012-12-06 |
Ct Atlantic Ltd. |
Magea3 binding antibodies
|
|
SG195253A1
(en)
|
2011-06-03 |
2013-12-30 |
Xoma Technology Ltd |
Antibodies specific for tgf-beta
|
|
TWI496886B
(zh)
*
|
2011-06-24 |
2015-08-21 |
Taipei Veteran General Hospital |
提升感染性與惡性疾病之治療之免疫反應
|
|
MY180616A
(en)
|
2011-06-30 |
2020-12-03 |
Genzyme Corp |
Inhibitors of t-cell activation
|
|
WO2013001517A1
(en)
|
2011-06-30 |
2013-01-03 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
|
EP2734232B1
(en)
|
2011-07-19 |
2017-11-01 |
Philogen S.p.A. |
Sequential anti-ctla4 and targeted il-2 therapy
|
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
|
US20150017157A1
(en)
|
2011-12-19 |
2015-01-15 |
Xoma (Us) Llc |
Methods for treating acne
|
|
KR20140126357A
(ko)
|
2012-02-01 |
2014-10-30 |
컴퓨젠 엘티디. |
C1orf32 항체 및 이의 암 치료를 위한 용도
|
|
WO2013156054A1
(en)
|
2012-04-16 |
2013-10-24 |
Universität Stuttgart |
The igm and ige heavy chain domain 2 as covalently linked homodimerization modules for the generation of fusion proteins with dual specificity
|
|
SG10201608307WA
(en)
|
2012-04-20 |
2016-11-29 |
Emergent Product Dev Seattle |
Cd3 binding polypeptides
|
|
US9328174B2
(en)
|
2012-05-09 |
2016-05-03 |
Novartis Ag |
Chemokine receptor binding polypeptides
|
|
WO2013171287A1
(en)
|
2012-05-16 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
Combination of cd37 antibodies with ice (ifosfamide, carboplatin, etoposide)
|
|
EP2861617A1
(en)
|
2012-06-15 |
2015-04-22 |
Pfizer Inc. |
Improved antagonist antibodies against gdf-8 and uses therefor
|
|
JP5600758B2
(ja)
*
|
2013-01-23 |
2014-10-01 |
バイエル・ファルマ・アクチェンゲゼルシャフト |
二量体分子複合体
|
|
SG11201600734YA
(en)
*
|
2013-07-31 |
2016-02-26 |
Amgen Inc |
Stabilization of fc-containing polypeptides
|
|
JP6463361B2
(ja)
|
2013-09-08 |
2019-01-30 |
コディアック サイエンシーズ インコーポレイテッドKodiak Sciences Inc. |
第viii因子両性イオンポリマーコンジュゲート
|
|
WO2015048901A1
(en)
|
2013-10-02 |
2015-04-09 |
Viventia Bio Inc. |
Anti-epcam antibodies and methods of use
|
|
SI3055331T1
(sl)
|
2013-10-11 |
2021-04-30 |
Oxford Bio Therapeutics Limited |
Konjugirana protitelesa proti LY75 za zdravljenje raka
|
|
PL3063275T3
(pl)
|
2013-10-31 |
2020-03-31 |
Resolve Therapeutics, Llc |
Terapeutyczne fuzje nukleaza-albumina i sposoby
|
|
WO2015070210A1
(en)
|
2013-11-11 |
2015-05-14 |
Wake Forest University Health Sciences |
Epha3 and multi-valent targeting of tumors
|
|
EP3077823B1
(en)
|
2013-12-05 |
2019-09-04 |
The Broad Institute, Inc. |
Compositions and methods for identifying and treating cachexia or pre-cachexia
|
|
SG10201900002QA
(en)
|
2014-01-24 |
2019-02-27 |
Dana Farber Cancer Institue Inc |
Antibody molecules to pd-1 and uses thereof
|
|
CN111909278B
(zh)
|
2014-01-27 |
2024-04-09 |
分子模板公司 |
Mhc i类表位递送多肽
|
|
EP3099717B1
(en)
|
2014-01-31 |
2019-03-27 |
Novartis AG |
Antibody molecules to tim-3 and uses thereof
|
|
US11142584B2
(en)
*
|
2014-03-11 |
2021-10-12 |
Molecular Templates, Inc. |
CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using same
|
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
CN113699159A
(zh)
|
2014-03-28 |
2021-11-26 |
明尼苏达大学评议会 |
涉及经工程改造的cd16的多肽、细胞和方法
|
|
IL292311A
(en)
|
2014-04-03 |
2022-06-01 |
Igm Biosciences Inc |
J-chain qualified
|
|
PL3248986T3
(pl)
|
2014-05-16 |
2022-05-16 |
Ablynx Nv |
Domeny zmienne immunoglobuliny
|
|
KR20250099289A
(ko)
|
2014-05-16 |
2025-07-01 |
아블린쓰 엔.브이. |
개선된 면역글로불린 가변 도메인
|
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
|
GB201411320D0
(en)
|
2014-06-25 |
2014-08-06 |
Ucb Biopharma Sprl |
Antibody construct
|
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
SG10201913765YA
(en)
|
2014-07-21 |
2020-03-30 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
TWI750110B
(zh)
|
2014-07-21 |
2021-12-21 |
瑞士商諾華公司 |
使用人類化抗-bcma嵌合抗原受體治療癌症
|
|
ES2781175T3
(es)
|
2014-07-31 |
2020-08-31 |
Novartis Ag |
Subconjunto optimizado de células T que contienen un receptor de antígeno quimérico
|
|
EP2985294A1
(en)
*
|
2014-08-14 |
2016-02-17 |
Deutsches Krebsforschungszentrum |
Recombinant antibody molecule and its use for target cell restricted T cell activation
|
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
|
ES2791248T3
(es)
|
2014-08-19 |
2020-11-03 |
Novartis Ag |
Receptor antigénico quimérico (CAR) anti-CD123 para su uso en el tratamiento del cáncer
|
|
WO2016044224A1
(en)
|
2014-09-15 |
2016-03-24 |
Amgen Inc. |
Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
|
|
KR20250067191A
(ko)
|
2014-09-17 |
2025-05-14 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
TWI716362B
(zh)
|
2014-10-14 |
2021-01-21 |
瑞士商諾華公司 |
針對pd-l1之抗體分子及其用途
|
|
KR20210013299A
(ko)
|
2014-10-17 |
2021-02-03 |
코디악 사이언시스 인코포레이티드 |
부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
|
|
EP3221351B1
(en)
*
|
2014-11-19 |
2024-11-13 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for cancer treating conditions relating to over expressions of epha2
|
|
EP3026060A1
(en)
*
|
2014-11-26 |
2016-06-01 |
Miltenyi Biotec GmbH |
Humanized antibody or fragment thereof specific for CD45R0
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
CN113862292B
(zh)
|
2015-01-29 |
2024-12-27 |
明尼苏达大学董事会 |
嵌合抗原受体、组合物以及方法
|
|
MX2017010072A
(es)
*
|
2015-02-05 |
2017-11-09 |
Molecular Templates Inc |
Moleculas multivalentes que se enlazan a cd20, las cuales comprenden regiones efectoras de la subunidad a de la toxina shiga, y composiciones enriquecidas de las mismas.
|
|
US10711067B2
(en)
|
2015-03-03 |
2020-07-14 |
Xoma (Us) Llc |
Treatment of post-prandial hyperinsulinemia and hypoglycemia after bariatric surgery
|
|
KR102357312B1
(ko)
|
2015-03-04 |
2022-02-03 |
아이쥐엠 바이오사이언스 인코포레이티드 |
Cd20 결합 분자 및 그의 용도
|
|
EP3268040A4
(en)
|
2015-03-12 |
2018-09-12 |
Viventia Bio Inc. |
Methods of treatment for epcam positive bladder cancer
|
|
US10583198B2
(en)
|
2015-03-12 |
2020-03-10 |
Viventia Bio Inc. |
Dosing strategies for targeting EPCAM positive bladder cancer
|
|
EP3770171A1
(en)
|
2015-04-03 |
2021-01-27 |
XOMA Technology Ltd. |
Treatment of cancer using inhibitors of tgf-beta and pd-1
|
|
RS61907B1
(sr)
|
2015-04-06 |
2021-06-30 |
Subdomain Llc |
Polipeptidi koji sadrže de novo vezujući domen i njihova primena
|
|
MX2017012939A
(es)
|
2015-04-08 |
2018-05-22 |
Novartis Ag |
Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
|
|
GB201506402D0
(en)
*
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CA2984794A1
(en)
|
2015-05-07 |
2016-11-10 |
Agenus Inc. |
Anti-ox40 antibodies and methods of use thereof
|
|
EP3154439A1
(en)
|
2015-05-19 |
2017-04-19 |
Yaya Diagnostics GmbH |
Means and methods for the enrichment of nucleic acids
|
|
AU2016271124C1
(en)
|
2015-05-30 |
2020-05-14 |
Molecular Templates, Inc. |
De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
|
HK1253694A1
(zh)
|
2015-06-01 |
2019-06-28 |
Medigene Immunotherapies Gmbh |
T细胞受体文库
|
|
WO2016193301A1
(en)
|
2015-06-01 |
2016-12-08 |
Medigene Immunotherapies Gmbh |
T-cell receptor specific antibodies
|
|
WO2016193300A1
(en)
|
2015-06-01 |
2016-12-08 |
Medigene Immunotherapies Gmbh |
Method for generating antibodies against t cell receptor
|
|
SG10202108116SA
(en)
|
2015-06-08 |
2021-08-30 |
Debiopharm International S A |
Anti-cd37 immunoconjugate and anti-cd20 antibody combinations
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
AU2016304588A1
(en)
|
2015-08-06 |
2018-02-15 |
Xoma (Us) Llc |
Antibody fragments against the insulin receptor and uses thereof to treat hypoglycemia
|
|
WO2017021023A1
(en)
|
2015-08-06 |
2017-02-09 |
Yaya Diagnostics Gmbh |
Means and methods for the detection of targets
|
|
US11104740B2
(en)
|
2015-08-28 |
2021-08-31 |
Debiopharm International, S.A. |
Antibodies and assays for detection of CD37
|
|
EP3352760B1
(en)
|
2015-09-21 |
2026-03-11 |
Aptevo Research and Development LLC |
Cd3 binding polypeptides
|
|
EP3824903A1
(en)
|
2015-09-30 |
2021-05-26 |
IGM Biosciences Inc. |
Binding molecules with modified j-chain
|
|
EP3356401B1
(en)
|
2015-09-30 |
2020-06-24 |
IGM Biosciences, Inc. |
Binding molecules with modified j-chain
|
|
IL299072A
(en)
|
2015-12-02 |
2023-02-01 |
Memorial Sloan Kettering Cancer Center |
Antibodies and methods for using them
|
|
EP3389715A4
(en)
|
2015-12-14 |
2019-06-12 |
David K. Thomas |
COMPOSITIONS AND METHODS FOR TREATING CARDIAL DYSFUNCTION
|
|
WO2017106656A1
(en)
|
2015-12-17 |
2017-06-22 |
Novartis Ag |
Antibody molecules to pd-1 and uses thereof
|
|
HK1254635A1
(zh)
|
2015-12-17 |
2019-07-26 |
Novartis Ag |
C-met抑制剂与pd-1抗体分子的组合及其用途
|
|
EP3393504B1
(en)
|
2015-12-22 |
2025-09-24 |
Novartis AG |
Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy
|
|
HUE053674T2
(hu)
|
2015-12-23 |
2021-07-28 |
Medigene Immunotherapies Gmbh |
Antigén-specifikus TCR receptorok új generációja
|
|
KR102799807B1
(ko)
|
2015-12-30 |
2025-04-24 |
코디악 사이언시스 인코포레이티드 |
항체 및 이의 접합체
|
|
WO2017125897A1
(en)
|
2016-01-21 |
2017-07-27 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
|
AU2017225733A1
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
|
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
CN109414489B
(zh)
|
2016-04-08 |
2022-08-16 |
埃缇健康公司D/B/A泽尔拜尔 |
网蛋白-1结合抗体及其用途
|
|
MY209117A
(en)
|
2016-04-15 |
2025-06-23 |
Novartis Ag |
Compositions and methods for selective protein expression
|
|
KR102682118B1
(ko)
|
2016-04-29 |
2024-07-08 |
주식회사유한양행 |
Ccl3 변이체를 포함하는 융합 단백질 및 이의 용도
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
JP7308034B2
(ja)
|
2016-07-01 |
2023-07-13 |
リゾルブ セラピューティクス, エルエルシー |
最適化二重ヌクレアーゼ融合物および方法
|
|
US20190336504A1
(en)
|
2016-07-15 |
2019-11-07 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
BR112019001570A2
(pt)
|
2016-07-28 |
2019-07-09 |
Novartis Ag |
terapias de combinação de receptores de antígeno quiméricos e inibidores de pd-1
|
|
US20190161542A1
(en)
|
2016-08-01 |
2019-05-30 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
WO2018026748A1
(en)
|
2016-08-01 |
2018-02-08 |
Xoma (Us) Llc |
Parathyroid hormone receptor 1 (pth1r) antibodies and uses thereof
|
|
US11259739B2
(en)
*
|
2016-08-12 |
2022-03-01 |
Phd Preventative Health Care And Diagnostics, Inc. |
Immunotherapy treatment kit and method of using the same
|
|
AU2017335771A1
(en)
|
2016-09-28 |
2019-02-28 |
Musc Foundation For Research Development |
Antibodies that bind interleukin-2 and uses thereof
|
|
EP3523331A1
(en)
|
2016-10-07 |
2019-08-14 |
Novartis AG |
Chimeric antigen receptors for the treatment of cancer
|
|
BR112019008010A2
(pt)
|
2016-10-20 |
2019-07-09 |
I-Mab |
anticorpo monoclonal isolado ou fragmento imunologicamente ativo do mesmo, anticorpo monoclonal biespecífico isolado, composição farmacêutica, método para tratamento de uma doença em um sujeito humano em necessidade do mesmo, proteína de fusão, epítopo imunodominante codificado pelo gene cd47, e, molécula biológica
|
|
US11278629B2
(en)
|
2016-11-02 |
2022-03-22 |
Debiopharm International, S.A. |
Methods for improving anti-CD37 immunoconjugate therapy
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
EP3538555A1
(en)
|
2016-11-14 |
2019-09-18 |
Amgen Inc. |
Bispecific or biparatopic antigen binding proteins and uses thereof
|
|
CA3043515A1
(en)
|
2016-11-16 |
2018-05-24 |
Ablynx Nv |
T cell recruiting polypeptides capable of binding cd123 and tcr alpha/beta
|
|
WO2018106895A1
(en)
|
2016-12-07 |
2018-06-14 |
Molecular Templates, Inc. |
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
|
|
RU2753493C2
(ru)
|
2016-12-15 |
2021-08-17 |
Эббви Байотерапьютикс Инк. |
Анти-ох40 антитела и их применение
|
|
CN116970059A
(zh)
|
2016-12-22 |
2023-10-31 |
库尔生物制药有限公司 |
T细胞调节性多聚体多肽及其使用方法
|
|
EP3575319A4
(en)
*
|
2016-12-30 |
2021-03-10 |
Shanghai Sinobio Biotech Co., Ltd. |
BIFUNCTIONAL MOLECULE AND USE OF IT
|
|
EP3573648B1
(en)
|
2017-01-25 |
2023-11-22 |
Molecular Templates, Inc. |
Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopes
|
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
EP3589647A1
(en)
|
2017-02-28 |
2020-01-08 |
Novartis AG |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
|
EP3601354A1
(en)
*
|
2017-03-31 |
2020-02-05 |
Genmab Holding B.V. |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
CN118307674A
(zh)
|
2017-06-22 |
2024-07-09 |
诺华股份有限公司 |
针对cd73的抗体分子及其用途
|
|
AU2018292618A1
(en)
|
2017-06-27 |
2019-12-19 |
Novartis Ag |
Dosage regimens for anti-TIM-3 antibodies and uses thereof
|
|
SG11201913137VA
(en)
|
2017-07-11 |
2020-01-30 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
|
CN111163798A
(zh)
|
2017-07-20 |
2020-05-15 |
诺华股份有限公司 |
用于抗lag-3抗体的给药方案及其用途
|
|
BR112020003670A2
(pt)
|
2017-08-22 |
2020-09-01 |
Sanabio, Llc |
receptores de interferon solúveis e usos dos mesmos
|
|
WO2019075216A1
(en)
*
|
2017-10-11 |
2019-04-18 |
Iti Health, Inc. D/B/A Zielbio |
ANTIBODIES BINDING TO PELTIN-1 AND USES THEREOF
|
|
EP3700542A4
(en)
|
2017-10-26 |
2020-12-09 |
Regents of the University of Minnesota |
RECOMBINANT IMMUNE CELLS, METHODS OF MANUFACTURING AND METHODS OF USE
|
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
AU2018369639C1
(en)
|
2017-11-14 |
2025-04-03 |
Arcellx, Inc. |
D-domain containing polypeptides and uses thereof
|
|
TW201922291A
(zh)
|
2017-11-16 |
2019-06-16 |
瑞士商諾華公司 |
組合療法
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
CN109957017A
(zh)
*
|
2017-12-25 |
2019-07-02 |
深圳宾德生物技术有限公司 |
一种靶向ox40的单链抗体、嵌合抗原受体t细胞及其制备方法和应用
|
|
CN109957022A
(zh)
*
|
2017-12-25 |
2019-07-02 |
深圳宾德生物技术有限公司 |
一种靶向ox40的单链抗体、嵌合抗原受体t细胞及其制备方法和应用
|
|
AU2019205743B2
(en)
*
|
2018-01-08 |
2023-11-16 |
Gi Innovation, Inc. |
Extracellular domain of alpha subunit of IgE Fc receptor, pharmaceutical composition comprising same and method for producing same
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
MX2020009152A
(es)
|
2018-03-02 |
2020-11-09 |
Kodiak Sciences Inc |
Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos.
|
|
US12152073B2
(en)
|
2018-03-14 |
2024-11-26 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
AU2019257343A1
(en)
|
2018-04-17 |
2020-09-10 |
Molecular Templates, Inc. |
HER2-targeting molecules comprising de-immunized, Shiga toxin A Subunit scaffolds
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
CA3099308A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US12144818B2
(en)
|
2018-05-30 |
2024-11-19 |
Debiopharm International, S.A. |
Method for treating cancer in a human patient by administering an anti-CD37 immunoconjugate using various dosing regimens
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
|
CN112654394B
(zh)
|
2018-06-19 |
2025-07-11 |
阿塔盖有限责任公司 |
针对补体成分5的抗体分子和其用途
|
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
US11492384B2
(en)
|
2018-09-17 |
2022-11-08 |
Gi Innovation, Inc. |
Fusion protein comprising IL-2 protein and CD80 protein, and use thereof
|
|
US11046769B2
(en)
|
2018-11-13 |
2021-06-29 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
|
GB201820547D0
(en)
|
2018-12-17 |
2019-01-30 |
Oxford Univ Innovation |
Modified antibodies
|
|
MX2021007391A
(es)
|
2018-12-20 |
2021-09-23 |
Novartis Ag |
Regimenes de baja dosis extendida para inhibidores de mdm2.
|
|
KR20210106437A
(ko)
|
2018-12-20 |
2021-08-30 |
노파르티스 아게 |
3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물
|
|
CN113490686B
(zh)
|
2019-01-07 |
2025-02-18 |
拜科托莱夫股份有限公司 |
病原体结合蛋白
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
CN113490528B
(zh)
|
2019-02-15 |
2024-12-03 |
诺华股份有限公司 |
3-(1-氧代-5-(哌啶-4-基)异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
JP7710373B2
(ja)
|
2019-02-21 |
2025-07-18 |
マレンゴ・セラピューティクス,インコーポレーテッド |
T細胞関連のがん細胞に結合する多機能性分子およびその使用
|
|
AU2020224681A1
(en)
|
2019-02-21 |
2021-09-16 |
Marengo Therapeutics, Inc. |
Antibody molecules that bind to NKp30 and uses thereof
|
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
EP3947454A1
(en)
*
|
2019-03-27 |
2022-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Recombinant proteins with cd40 activating properties
|
|
KR20220029546A
(ko)
|
2019-03-29 |
2022-03-08 |
아타르가, 엘엘씨 |
항 fgf23 항체
|
|
MA55529A
(fr)
|
2019-04-03 |
2022-02-09 |
Genzyme Corp |
Polypeptides de liaison anti-alpha bêta tcr à fragmentation réduite
|
|
JP7500619B2
(ja)
|
2019-05-30 |
2024-06-17 |
アムジエン・インコーポレーテツド |
抗体の二量体化を促進するためのヒンジ領域の操作
|
|
EP4582442A3
(en)
|
2019-06-24 |
2025-10-29 |
Universität Stuttgart |
Tnfr2 agonists with improved stability
|
|
AU2020304671A1
(en)
|
2019-06-28 |
2022-01-20 |
Amgen Inc. |
Anti-CGRP receptor/anti-PAC1 receptor bispecific antigen binding proteins
|
|
GB201910900D0
(en)
*
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
|
|
CN114867751B
(zh)
|
2019-08-12 |
2024-11-29 |
阿帕特夫研究和发展有限公司 |
4-1bb和ox40结合蛋白及相关组合物和方法、抗-4-1bb抗体、抗-ox40抗体
|
|
JP2022550316A
(ja)
*
|
2019-09-25 |
2022-12-01 |
ウニヴェルズィテート シュトゥットガルト |
修飾ehd2ドメインを含む結合モジュール
|
|
CA3157509A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
CN114786679A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
具有维奈托克和tim-3抑制剂的组合疗法
|
|
TW202128191A
(zh)
|
2019-10-21 |
2021-08-01 |
瑞士商諾華公司 |
Tim-3抑制劑及其用途
|
|
WO2021091906A1
(en)
|
2019-11-04 |
2021-05-14 |
Amgen Inc. |
Methods for treating leukemia
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
MX2022007759A
(es)
|
2019-12-20 |
2022-07-19 |
Novartis Ag |
Combinacion del anticuerpo anti tim-3 mbg453 y anticuerpo anti tgf-beta nis793, con o sin decitabina o el anticuerpo anti pd-1 spartalizumab, para el tratamiento de mielofibrosis y sindrome mielodisplasico.
|
|
CN116234829A
(zh)
|
2020-01-03 |
2023-06-06 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
CN115298322A
(zh)
|
2020-01-17 |
2022-11-04 |
贝克顿迪金森公司 |
用于单细胞分泌组学的方法和组合物
|
|
JP2023510393A
(ja)
|
2020-01-17 |
2023-03-13 |
ノバルティス アーゲー |
骨髄異形成症候群または慢性骨髄単球性白血病の処置に使用するためのtim-3阻害剤と低メチル化剤とを含む組合せ
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
TW202208395A
(zh)
|
2020-05-12 |
2022-03-01 |
美商信號生物製藥公司 |
多聚體t細胞調節多肽及其使用方法
|
|
EP4225787A4
(en)
*
|
2020-05-21 |
2024-10-23 |
Zydus Lifesciences Limited |
FC VARIANT AND PRODUCTION THEREOF
|
|
US20230257703A1
(en)
*
|
2020-06-19 |
2023-08-17 |
Iowa State University Research Foundation, Inc. |
Nanoscale polymeric micellar scaffolds for rapid and efficient antibody production
|
|
CN115916199A
(zh)
|
2020-06-23 |
2023-04-04 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案
|
|
PH12023550015A1
(en)
|
2020-07-16 |
2024-03-11 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
US20230321285A1
(en)
|
2020-08-31 |
2023-10-12 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
EP4214233A1
(en)
|
2020-09-16 |
2023-07-26 |
Amgen Inc. |
Methods for administering therapeutic doses of bispecific t-cell engaging molecules for the treatment of cancer
|
|
WO2022060878A1
(en)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Methods for treating prostate cancer
|
|
CN116261662B
(zh)
*
|
2020-10-14 |
2024-05-31 |
天境生物科技(上海)有限公司 |
用于减轻输血前测定中治疗性抗cd47抗体的干扰的方法
|
|
JP2023547499A
(ja)
|
2020-11-06 |
2023-11-10 |
ノバルティス アーゲー |
抗体Fc変異体
|
|
KR20230107617A
(ko)
|
2020-11-13 |
2023-07-17 |
노파르티스 아게 |
키메라 항원 수용체(car)-발현 세포를 사용한 병용 요법
|
|
US20240301086A1
(en)
|
2020-12-01 |
2024-09-12 |
Aptevo Research And Development Llc |
Tumor-associated antigens and cd3-binding proteins, related compositions, and methods
|
|
WO2022162569A1
(en)
|
2021-01-29 |
2022-08-04 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
CA3209052A1
(en)
|
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2022-08-25 |
Rafael Cristian CASELLAS |
Single domain antibodies that neutralize sars-cov-2
|
|
CN113512109B
(zh)
*
|
2021-03-09 |
2022-03-25 |
北京康乐卫士生物技术股份有限公司 |
一种抗人乳头瘤病毒31型的单克隆中和抗体及其应用
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
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抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
JP2024515301A
(ja)
|
2021-04-20 |
2024-04-08 |
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多重特異性及び一価のigg分子の会合における鎖対形成の静電ステアリングにおけるバランスのとれた電荷分布
|
|
JP2024517701A
(ja)
|
2021-04-29 |
2024-04-23 |
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組換え生産タンパク質の低分子量種を低減させる方法
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
MX2023015461A
(es)
*
|
2021-06-17 |
2024-01-18 |
Fapon Biotech Inc |
Inmunoglobulina quimerica.
|
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
EP4405398A4
(en)
|
2021-09-21 |
2025-10-29 |
Qilu Puget Sound Biotherapeutics Corp |
FC HETERODIMERS ALLOWING THE MANUFACTURE OF FUSION PROTEINS AND BI-SPECIFIC ANTIBODIES
|
|
TW202323281A
(zh)
|
2021-10-14 |
2023-06-16 |
美商泰尼歐生物公司 |
間皮素結合蛋白及其用途
|
|
US20250034559A1
(en)
|
2021-11-17 |
2025-01-30 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2023150778A1
(en)
|
2022-02-07 |
2023-08-10 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
|
CN115286701A
(zh)
*
|
2022-03-07 |
2022-11-04 |
江苏靶标生物医药研究所有限公司 |
一种调节哺乳动物的肠道粘膜稳态或炎症性肠病的靶点及其应用
|
|
US20260001962A1
(en)
|
2022-03-21 |
2026-01-01 |
Amgen Inc. |
Combination therapy methods with t-cell engaging molecules for treatment of prostate cancer
|
|
CN114591988B
(zh)
*
|
2022-03-30 |
2023-01-13 |
北京贝来生物科技有限公司 |
一种激活肿瘤免疫的基因修饰干细胞制备方法
|
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
EP4561613A1
(en)
|
2022-07-27 |
2025-06-04 |
Teneobio, Inc. |
Mesothelin binding proteins and uses thereof
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
EP4581570A1
(en)
|
2022-08-30 |
2025-07-09 |
Amgen Inc. |
Live cell profiling assay
|
|
CN120153061A
(zh)
|
2022-09-06 |
2025-06-13 |
美国安进公司 |
精简灌注细胞培养方法
|
|
EP4598958A1
(en)
|
2022-10-05 |
2025-08-13 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
|
EP4605077A1
(en)
|
2022-10-18 |
2025-08-27 |
Confo Therapeutics N.V. |
Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders
|
|
KR20250143321A
(ko)
|
2023-02-02 |
2025-10-01 |
암젠 인크 |
세포 배양 수확 프로세스 동안 치료 단백질 단편화의 완화
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
CN121079323A
(zh)
|
2023-02-21 |
2025-12-05 |
特尼奥生物股份有限公司 |
c-Kit结合蛋白、嵌合抗原受体及其用途
|
|
TW202502797A
(zh)
|
2023-03-13 |
2025-01-16 |
美商安進公司 |
使用超大病毒預濾器的病毒過濾操作
|
|
AU2024235093A1
(en)
|
2023-03-14 |
2025-09-04 |
Amgen Inc. |
Anion exchange chromatography processes using a primary amine ligand
|
|
US20240426793A1
(en)
|
2023-06-20 |
2024-12-26 |
Amgen Inc. |
Methods for chromatography and chromatography medium reuse
|
|
AR134267A1
(es)
|
2023-11-08 |
2025-12-17 |
Sanofi Sa |
Degradador lisosómico basado en cd25 y usos del mismo
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
TW202548027A
(zh)
|
2024-01-23 |
2025-12-16 |
美商安進公司 |
用於調節單株抗體電荷變體之方法
|
|
WO2025160446A1
(en)
*
|
2024-01-25 |
2025-07-31 |
Ai Proteins, Inc. |
Methods and systems for characterizing structural features of a protein
|
|
TW202602923A
(zh)
|
2024-02-29 |
2026-01-16 |
美商安進公司 |
升糖素受體促效劑及與葡萄糖依賴性促胰島素多肽拮抗劑之軛合物
|
|
US20250288957A1
(en)
|
2024-03-14 |
2025-09-18 |
Amgen Inc. |
Intensified ultrafiltration/diafiltration processes
|
|
TW202602940A
(zh)
|
2024-04-09 |
2026-01-16 |
美商安進公司 |
激動性抗il-2rbg重鏈抗體
|
|
EP4635980A1
(en)
|
2024-04-19 |
2025-10-22 |
Medigene Immunotherapies GmbH |
Uni-tags specific antibody
|
|
WO2025251034A1
(en)
|
2024-05-31 |
2025-12-04 |
Amgen Inc. |
Purification method
|
|
WO2026036047A1
(en)
|
2024-08-08 |
2026-02-12 |
Altus Enterprises, Inc. |
Antibody molecules to fixa and fx and uses thereof
|
|
WO2026058155A1
(en)
|
2024-09-11 |
2026-03-19 |
Novartis Ag |
Antibodies targeting il-31
|