JP2006230415A5 - - Google Patents

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Publication number
JP2006230415A5
JP2006230415A5 JP2006147486A JP2006147486A JP2006230415A5 JP 2006230415 A5 JP2006230415 A5 JP 2006230415A5 JP 2006147486 A JP2006147486 A JP 2006147486A JP 2006147486 A JP2006147486 A JP 2006147486A JP 2006230415 A5 JP2006230415 A5 JP 2006230415A5
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JP
Japan
Prior art keywords
cells
mdck
influenza virus
mdck cells
cell
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JP2006147486A
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JP2006230415A (ja
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Priority claimed from DE19612966A external-priority patent/DE19612966B4/de
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Publication of JP2006230415A publication Critical patent/JP2006230415A/ja
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Claims (5)

  1. インフルエンザウイルスによって感染され得るＭＤＣＫ細胞であって、該細胞がMDCK細胞（ATCCCCL34 MDCK(NBL-2)）由来であり、かつ、該ＭＤＣＫ細胞は無血清培地の懸濁物に
    おける増殖に適合する、ＭＤＣＫ細胞。
  2. 前記細胞が細胞株MDCK33016（DSM ACC2219）である、請求項１に記載のＭＤＣＫ細胞。
  3. 細胞培養におけるインフルエンザウイルスの複製のための方法であって、
    （i）懸濁物中の無血清培地において、ＭＤＣＫ細胞を増殖させる工程であって、該MDCK細胞は、インフルエンザウイルスによって感染され得、MDCK細胞（ATCCCCL34MDCK(NBL-2)）由来であり、かつ、該ＭＤＣＫ細胞は無血清培地の懸濁物における増殖に適合するものであるか、または
    細胞株MDCK33016（DSM ACC2219）である、工程；
    （ii）該細胞をインフルエンザウイルスに感染させる工程；
    （iii）感染直前、または感染と同時に細胞懸濁物にプロテアーゼを添加し、赤血球凝集素[HA 0 ]の前駆体タンパク質を切断する工程；および
    （iv）さらなる培養期の後、該細胞中で複製した該インフルエンザウイルスを単離する工程；
    を含む、方法によって入手されうるインフルエンザウイルス。
  4. 請求項３に記載のインフルエンザウイルスまたは該ウイルスの成分を含む、診断薬。
  5. 実施例に記載されるMDCK細胞株。
JP2006147486A 1996-04-01 2006-05-26 インフルエンザウイルスの複製のための動物細胞および方法 Withdrawn JP2006230415A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612966A DE19612966B4 (de) 1996-04-01 1996-04-01 MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren

Related Parent Applications (1)

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JP2005108075A Division JP2005211080A (ja) 1996-04-01 2005-04-04 インフルエンザウイルスの複製のための動物細胞および方法

Related Child Applications (1)

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JP2008287206A Division JP2009034115A (ja) 1996-04-01 2008-11-07 インフルエンザウイルスの複製のための動物細胞および方法

Publications (2)

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JP2006230415A JP2006230415A (ja) 2006-09-07
JP2006230415A5 true JP2006230415A5 (ja) 2008-03-13

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ID=7790126

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JP53508997A Expired - Fee Related JP4243349B2 (ja) 1996-04-01 1997-04-01 インフルエンザウイルスの複製のための動物細胞および方法
JP2004233905A Withdrawn JP2004331673A (ja) 1996-04-01 2004-08-10 インフルエンザウイルスの複製のための動物細胞および方法
JP2005108075A Withdrawn JP2005211080A (ja) 1996-04-01 2005-04-04 インフルエンザウイルスの複製のための動物細胞および方法
JP2006147486A Withdrawn JP2006230415A (ja) 1996-04-01 2006-05-26 インフルエンザウイルスの複製のための動物細胞および方法
JP2008287206A Withdrawn JP2009034115A (ja) 1996-04-01 2008-11-07 インフルエンザウイルスの複製のための動物細胞および方法
JP2011192118A Withdrawn JP2012005502A (ja) 1996-04-01 2011-09-02 インフルエンザウイルスの複製のための動物細胞および方法
JP2011224914A Withdrawn JP2012016358A (ja) 1996-04-01 2011-10-12 インフルエンザウイルスの複製のための動物細胞および方法

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JP53508997A Expired - Fee Related JP4243349B2 (ja) 1996-04-01 1997-04-01 インフルエンザウイルスの複製のための動物細胞および方法
JP2004233905A Withdrawn JP2004331673A (ja) 1996-04-01 2004-08-10 インフルエンザウイルスの複製のための動物細胞および方法
JP2005108075A Withdrawn JP2005211080A (ja) 1996-04-01 2005-04-04 インフルエンザウイルスの複製のための動物細胞および方法

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JP2008287206A Withdrawn JP2009034115A (ja) 1996-04-01 2008-11-07 インフルエンザウイルスの複製のための動物細胞および方法
JP2011192118A Withdrawn JP2012005502A (ja) 1996-04-01 2011-09-02 インフルエンザウイルスの複製のための動物細胞および方法
JP2011224914A Withdrawn JP2012016358A (ja) 1996-04-01 2011-10-12 インフルエンザウイルスの複製のための動物細胞および方法

Country Status (10)

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US (4) US6455298B1 (ja)
EP (2) EP0904351B1 (ja)
JP (7) JP4243349B2 (ja)
AT (1) ATE482267T1 (ja)
DE (2) DE19612966B4 (ja)
DK (1) DK0904351T3 (ja)
ES (1) ES2352638T3 (ja)
HK (1) HK1019233A1 (ja)
PT (1) PT904351E (ja)
WO (1) WO1997037000A1 (ja)

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