JP2003506425A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2003506425A5 JP2003506425A5 JP2001515282A JP2001515282A JP2003506425A5 JP 2003506425 A5 JP2003506425 A5 JP 2003506425A5 JP 2001515282 A JP2001515282 A JP 2001515282A JP 2001515282 A JP2001515282 A JP 2001515282A JP 2003506425 A5 JP2003506425 A5 JP 2003506425A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- defined above
- naphthyl
- methoxy
- range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI001753A IT1313596B1 (it) | 1999-08-04 | 1999-08-04 | Processo per la preparazione di nitrossialchil esteri del naproxene |
| IT99A001753 | 1999-08-04 | ||
| PCT/EP2000/007222 WO2001010814A1 (en) | 1999-08-04 | 2000-07-27 | Process for the preparation of naproxene nitroxyalkylesters |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010266860A Division JP2011042690A (ja) | 1999-08-04 | 2010-11-30 | ナプロキセンのニトロキシアルキルエステル |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003506425A JP2003506425A (ja) | 2003-02-18 |
| JP2003506425A5 true JP2003506425A5 (https=) | 2007-09-13 |
| JP4667691B2 JP4667691B2 (ja) | 2011-04-13 |
Family
ID=11383500
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001515282A Expired - Lifetime JP4667691B2 (ja) | 1999-08-04 | 2000-07-27 | ナプロキセンのニトロキシアルキルエステルの製造法 |
| JP2010266860A Pending JP2011042690A (ja) | 1999-08-04 | 2010-11-30 | ナプロキセンのニトロキシアルキルエステル |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010266860A Pending JP2011042690A (ja) | 1999-08-04 | 2010-11-30 | ナプロキセンのニトロキシアルキルエステル |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US6700011B1 (https=) |
| EP (2) | EP1200386B1 (https=) |
| JP (2) | JP4667691B2 (https=) |
| KR (1) | KR100687820B1 (https=) |
| CN (1) | CN1198786C (https=) |
| AT (2) | ATE251109T1 (https=) |
| AU (1) | AU778694B2 (https=) |
| BR (1) | BRPI0012915B1 (https=) |
| CA (1) | CA2380116C (https=) |
| DE (2) | DE60005682T2 (https=) |
| DK (2) | DK1200386T3 (https=) |
| ES (2) | ES2243859T3 (https=) |
| HU (1) | HU227109B1 (https=) |
| IL (1) | IL147639A0 (https=) |
| IT (1) | IT1313596B1 (https=) |
| MX (1) | MXPA02001256A (https=) |
| NO (1) | NO327669B1 (https=) |
| PL (1) | PL200165B1 (https=) |
| PT (2) | PT1384707E (https=) |
| RU (1) | RU2248348C2 (https=) |
| TR (1) | TR200200290T2 (https=) |
| WO (1) | WO2001010814A1 (https=) |
| ZA (2) | ZA200200478B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6297260B1 (en) | 1998-10-30 | 2001-10-02 | Nitromed, Inc. | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| AP2002002582A0 (en) | 1999-12-23 | 2002-09-30 | Nitromed Inc | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
| DE60122939T2 (de) | 2000-12-21 | 2007-01-11 | Nitromed, Inc., Bedford | Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren |
| AU2002365372A1 (en) * | 2001-11-27 | 2003-06-10 | Astrazeneca Ab | New process |
| CA2487414A1 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| US7244753B2 (en) | 2002-07-29 | 2007-07-17 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| ITMI20021861A1 (it) | 2002-08-29 | 2004-02-29 | Nicox Sa | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
| ITMI20022409A1 (it) * | 2002-11-14 | 2004-05-15 | Dinamite Dipharma S P A | Procedimento per la purificazione di 1, 4-butandiolo mononitrato. |
| NZ569396A (en) * | 2006-02-03 | 2011-06-30 | Nicox Sa | Use of nitrooxyderivative of drug for the treatment of muscular dystrophies |
| CN100427475C (zh) * | 2006-11-30 | 2008-10-22 | 华南理工大学 | 萘普生-2-芳基吗啉乙酯及其制备方法与应用 |
| JP2010531324A (ja) * | 2007-06-28 | 2010-09-24 | ニコックス エス エイ | １，４−ブタンジオールモノナイトレートの製造方法 |
| WO2009149053A2 (en) * | 2008-06-02 | 2009-12-10 | Dr. Reddy's Laboratories Ltd. | Naproxcinod process and solid dispersion |
| ITRM20080325A1 (it) * | 2008-06-20 | 2009-12-21 | Nicox Sa | Metodo per purificare 4-(nitroosi)butil(2s)-2-(6-metossi-2-naftil) propanoato |
| TW201139337A (en) | 2010-03-31 | 2011-11-16 | Lonza Ag | Process for the production of esters of nitric acid |
| TWI417276B (zh) | 2011-03-01 | 2013-12-01 | Everlight Chem Ind Corp | ２-（ｓ）-（６-甲氧基-２-萘基）-丙酸之酸酐衍生物、其製法暨及其用途 |
| CA2897571C (en) | 2013-01-21 | 2018-12-18 | Apparao Satyam | Nitric oxide releasing prodrugs of therapeutic agents containing at least one carboxylic acid group |
| CA3167343A1 (en) | 2020-02-10 | 2021-08-19 | Brigitte DUQUESROIX-CHAKROUN | Method for treating vaso occlusive crises associated with sickle cell disease |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57145841A (en) * | 1981-03-05 | 1982-09-09 | Nissan Chem Ind Ltd | L-menthyl naphthylpropionate and its preparation |
| IT1243367B (it) * | 1990-07-26 | 1994-06-10 | Italfarmaco Spa | Derivati acidi benzoici sostituiti ad attivita' cardiovascolare |
| EP0722434B1 (en) * | 1993-10-06 | 1998-07-29 | Nicox S.A. | Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation |
| WO1995030641A1 (en) * | 1994-05-10 | 1995-11-16 | Nicox S.A. | Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities |
| US5703073A (en) * | 1995-04-19 | 1997-12-30 | Nitromed, Inc. | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs |
| CN1144092A (zh) * | 1995-08-25 | 1997-03-05 | 蔡雄 | 可释放一氧化氮的新型非类固醇类抗炎药、它们的制备方法和用途 |
| WO1997013519A1 (en) * | 1995-10-09 | 1997-04-17 | Russinsky Limited | Esters of cyclooxygenase inhibitors and terpene derivatives as pharmaceutical products |
| IT1276071B1 (it) | 1995-10-31 | 1997-10-24 | Nicox Ltd | Compositi ad attivita' anti-infiammatoria |
| FR2757159B1 (fr) | 1996-12-12 | 1999-12-17 | Hoechst Marion Roussel Inc | Nouveaux derives nitres analgesiques, anti-inflammatoires et anti-thrombotiques, leur procede de preparation, leur application comme medicaments |
-
1999
- 1999-08-04 IT IT1999MI001753A patent/IT1313596B1/it active
-
2000
- 2000-07-27 KR KR1020027000946A patent/KR100687820B1/ko not_active Expired - Fee Related
- 2000-07-27 JP JP2001515282A patent/JP4667691B2/ja not_active Expired - Lifetime
- 2000-07-27 RU RU2002102860/04A patent/RU2248348C2/ru active
- 2000-07-27 DK DK00951456T patent/DK1200386T3/da active
- 2000-07-27 US US10/031,412 patent/US6700011B1/en not_active Expired - Lifetime
- 2000-07-27 BR BRPI0012915-1A patent/BRPI0012915B1/pt not_active IP Right Cessation
- 2000-07-27 DE DE60005682T patent/DE60005682T2/de not_active Expired - Lifetime
- 2000-07-27 PL PL353092A patent/PL200165B1/pl unknown
- 2000-07-27 DK DK03102132T patent/DK1384707T3/da active
- 2000-07-27 AU AU64385/00A patent/AU778694B2/en not_active Ceased
- 2000-07-27 DE DE60020753T patent/DE60020753T2/de not_active Expired - Lifetime
- 2000-07-27 EP EP00951456A patent/EP1200386B1/en not_active Expired - Lifetime
- 2000-07-27 PT PT03102132T patent/PT1384707E/pt unknown
- 2000-07-27 PT PT00951456T patent/PT1200386E/pt unknown
- 2000-07-27 CA CA2380116A patent/CA2380116C/en not_active Expired - Lifetime
- 2000-07-27 EP EP03102132A patent/EP1384707B1/en not_active Expired - Lifetime
- 2000-07-27 TR TR2002/00290T patent/TR200200290T2/xx unknown
- 2000-07-27 IL IL14763900A patent/IL147639A0/xx not_active IP Right Cessation
- 2000-07-27 CN CNB008111588A patent/CN1198786C/zh not_active Expired - Fee Related
- 2000-07-27 WO PCT/EP2000/007222 patent/WO2001010814A1/en not_active Ceased
- 2000-07-27 HU HU0202435A patent/HU227109B1/hu not_active IP Right Cessation
- 2000-07-27 ES ES03102132T patent/ES2243859T3/es not_active Expired - Lifetime
- 2000-07-27 AT AT00951456T patent/ATE251109T1/de active
- 2000-07-27 ES ES00951456T patent/ES2208390T3/es not_active Expired - Lifetime
- 2000-07-27 AT AT03102132T patent/ATE297372T1/de active
- 2000-07-27 MX MXPA02001256A patent/MXPA02001256A/es active IP Right Grant
-
2002
- 2002-01-18 ZA ZA200200478A patent/ZA200200478B/en unknown
- 2002-02-01 NO NO20020515A patent/NO327669B1/no not_active IP Right Cessation
-
2003
- 2003-06-10 ZA ZA200304525A patent/ZA200304525B/xx unknown
- 2003-07-24 US US10/625,558 patent/US7238829B2/en not_active Expired - Lifetime
-
2010
- 2010-11-30 JP JP2010266860A patent/JP2011042690A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2003506425A5 (https=) | ||
| RU2002102860A (ru) | Способ получения нитроксиалкиловых эфиров напроксена | |
| JP2005516094A5 (https=) | ||
| JP2005526011A5 (https=) | ||
| JP2004501940A5 (https=) | ||
| SE7909655L (sv) | Sett att framstella treo-3-amino-2-hydroxibutyrylaminoettiksyror samt even nya mellanprodukter derfor och sett att framstella dessa | |
| KR970042473A (ko) | 유기주석 촉매를 사용하는 트랜스에스테르화 방법 | |
| EP0738703A3 (en) | Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers | |
| ZA984635B (en) | Orally active iron (III) chelators. | |
| NO20024241L (no) | FremgangsmÕte for fremstilling av citalopram | |
| JP2002511433A5 (https=) | ||
| EP1335247A3 (en) | Light sensitive composition, light sensitive planographic printing plate precursor, and image formation method | |
| RU2004139042A (ru) | Способ получения эфиров диоксануксусной кислоты | |
| JP2003503409A5 (https=) | ||
| JP2005502603A5 (https=) | ||
| CA2057734A1 (en) | Oxidized-type glutathione alkyl ester | |
| KR850001202A (ko) | 아로일 벤조푸란 및 벤조티오펜 아세트산 및 프로피온산의 제조방법 | |
| ATE45738T1 (de) | 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3 dioxol-4-yl-methyl)-1-piperazinyl>-3chinolincarbons|uren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel. | |
| JPH1112272A5 (https=) | ||
| JP2006509753A5 (https=) | ||
| JP2006500435A5 (https=) | ||
| RU93005087A (ru) | 3-(тиазолидинилбутил-4-пиперазинил)-ih-индазолы | |
| KR930007880A (ko) | 비스(페닐)에탄 유도체 | |
| DE2962919D1 (en) | 2,4,6-triiodo-isophthalamic acid derivatives, their preparation and x-ray contrast agents based on these compounds | |
| KR830001292A (ko) | 3-엑소메틸렌세팜 설폭사이드류의 제법 |