JP2001511049A - 生体内で分解可能な金属のインプラント - Google Patents
生体内で分解可能な金属のインプラントInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/1204—Type of occlusion temporary occlusion
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- A—HUMAN NECESSITIES
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- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
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- A—HUMAN NECESSITIES
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- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12104—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in an air passage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
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- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
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- A—HUMAN NECESSITIES
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- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
- A61B17/86—Pins or screws or threaded wires; nuts therefor
- A61B17/866—Material or manufacture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00017—Iron- or Fe-based alloys, e.g. stainless steel
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- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.金属材料からなる、医療用のインプラントにおいて、 材料が生体内で腐食によって分解可能であることを特徴とする医療用のインプ ラント。 2.材料が純鉄または合金であって、その合金の主成分が次のもの、すなわち : アルカリ金属、アルカリ土類金属、鉄、亜鉛、アルミニウムを含むグループか ら選択されていることを特徴とする請求項1に記載の医療用のインプラント。 3.材料が、主成分としてマグネシウム、鉄または亜鉛を含むことを特徴とす る請求項1または2に記載の医療用のインプラント。 4.材料が、鉄と0.5−7%の炭素を含むことを特徴とする請求項1から3 までののいずれか1項に記載の医療用のインプラント。 5.材料が、ほぼ同じ濃度の鉄と亜鉛を含むことを特徴とする請求項1から4 までのいずれか1項に記載の医療用のインプラント。 6.材料が、副成分として、次のもの、すなわち: Mn、Co、Ni、Cr、Cu、Cd、Pb、Sn、Th、Zr、Ag、Au 、Pd、Pt、Re、Si、Ca、Li、Al、Zn、Fe、C、S を含むグループの1つまたは複数の要素を有することを特徴とする請求項1から 5までのいずれか1項に記載の医療用のインプラント。 7.材料が、50−98%のマグネシウム、0−40%のリチウム、0−5% の鉄と5%より少ない他の金属または希土類元素を含むことを特徴とする請求項 1から6までのいずれか1項に記載の医 療用のインプラント。 8.材料が、79−97%のマグネシウム、2−5%のアルミニウム、0−1 2%のリチウムおよび1−4%の希土類元素、特にセリウム、ランタン、ネオジ ムおよび/またはプラセオジムを含むことを特徴とする請求項1から7までのい ずれか1項に記載の医療用のインプラント。 9.材料が、85−91%のマグネシウム、6−12%のリチウム、2%のア ルミニウムおよび1%の希土類元素を含むことを特徴とする請求項1から8まで のいずれか1項に記載の医療用のインプラント。 10.材料が、86−97%のマグネシウム、0−8%のリチウム、2−4% のアルミニウムおよび1−2%の希土類元素を含むことを特徴とする請求項1か ら9までのいずれか1項に記載の医療用のインプラント。 11.材料が、8.5−9.5%のアルミニウム、0.15−0.4%のマン ガン、0.45−0.9%の亜鉛および100%にするための残り%のマグネシ ウムを含むことを特徴とする請求項1から10までのいずれか1項に記載の医療 用のインプラント。 12.材料が、4.5−5.3%のアルミニウム、0.28−0.5%のマン ガンおよび100%にするための残り%のマグネシウムを含むことを特徴とする 請求項1から11までのいずれか1項に記載の医療用のインプラント。 13.材料が、55−65%のマグネシウム、30−40%のリチウムおよび 0−5%の他の金属および/または希土類元素を含むことを特徴とする請求項1 から12までのいずれか1項に記載の医療用のインプラント。 14.材料が、88−99.8%の鉄、0.1−7%のクロムお よび0−3.5%のニッケル並びに5%より少ない他の金属を含むことを特徴と する請求項1から13までのいずれか1項に記載の医療用のインプラント。 15.材料が、90−96%の鉄、3−6%のクロムおよび0−3%のニッケ ル並びに0−5%の他の金属を含むことを特徴とする請求項1から14までのい ずれか1項に記載の医療用のインプラント。 16.インプラントが、脉管支持部材であることを特徴とする請求項1から1 5のいずれか1項に記載の医療用のインプラント。 17.インプラントが、ほぼ管形状の基体を有することを特徴とする請求項1 から16までのいずれか1項に記載の医療用のインプラント。 18.インプラントが、螺旋(コイル)、シールド、ステント、ワイヤ編物、 クリップまたは栓であることを特徴とする請求項1から17までのいずれか1項 に記載の医療用のインプラント。 19.インプラントが、中空器官および/または管系(たとえば尿管、胆管、 尿道、子宮、気管支)内の内腔支持機能を有することを特徴とする請求項1から 18までのいずれか1項に記載の医療用のインプラント。 20.インプラントが、中空空間接続、脉管または管系のための閉鎖システム としての閉鎖部材(Okkluder)であることを特徴とする請求項1から1 9までのいずれか1項に記載の医療用のインプラント。 21.インプラントが、組織インプラントまたは組織トランスプラントを一時 的に固定するための固定または支持装置であることを特徴とする請求項1から2 0までのいずれか1項に記載の医療用のインプラント。 22.インプラントが、整形外科用のインプラント、たとえばボルト、釘、ワ イヤ、プレートまたは関節の一部であることを特徴とする請求項1から21まで のいずれか1項に記載の医療用のインプラント。 23.材料の材厚が、材料の組成に従って、生体内での分解または腐食プロセ スが5日から6ヶ月、特に2週間から8週間の範囲でほぼ終了するように、選択 されていることを特徴とする請求項1から22までのいずれか1項に記載の医療 用のインプラント。 24.材料の材厚が、材料の組成に従って、生体内での分解または腐食プロセ スが、6ヶ月から10年、特に1年から5年の範囲でほぼ終了するように、選択 されていることを特徴とする請求項1から16までのいずれか1項に記載の医療 用のインプラント。 25.生体内の分解または腐食プロセスは、分解プロセスがほぼ終了する前に 、まず機械的な非安定性をもたらすことを特徴とする請求項1から24までのい ずれか1項に記載の医療用のインプラント。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19731021.4 | 1997-07-18 | ||
DE19731021A DE19731021A1 (de) | 1997-07-18 | 1997-07-18 | In vivo abbaubares metallisches Implantat |
PCT/EP1998/004415 WO1999003515A2 (de) | 1997-07-18 | 1998-07-17 | In vivo abbaubares metallisches implantat |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009208920A Division JP2009297537A (ja) | 1997-07-18 | 2009-09-10 | 生体内で分解可能な金属のインプラント |
JP2010249076A Division JP2011031063A (ja) | 1997-07-18 | 2010-11-05 | 生体内で分解可能な金属のインプラント |
Publications (2)
Publication Number | Publication Date |
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JP2001511049A true JP2001511049A (ja) | 2001-08-07 |
JP5352776B2 JP5352776B2 (ja) | 2013-11-27 |
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JP50644199A Expired - Lifetime JP5352776B2 (ja) | 1997-07-18 | 1998-07-17 | 生体内で分解可能な金属のインプラント |
JP2009208920A Pending JP2009297537A (ja) | 1997-07-18 | 2009-09-10 | 生体内で分解可能な金属のインプラント |
JP2010249076A Pending JP2011031063A (ja) | 1997-07-18 | 2010-11-05 | 生体内で分解可能な金属のインプラント |
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US (3) | US7879367B2 (ja) |
EP (3) | EP0923389B1 (ja) |
JP (3) | JP5352776B2 (ja) |
AT (2) | ATE236667T1 (ja) |
AU (1) | AU9154198A (ja) |
DE (3) | DE19731021A1 (ja) |
DK (1) | DK1270023T3 (ja) |
ES (2) | ES2243635T3 (ja) |
IL (3) | IL129065A0 (ja) |
PT (1) | PT1270023E (ja) |
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EP0923389A3 (de) | 2002-08-28 |
ES2243635T3 (es) | 2005-12-01 |
ATE297767T1 (de) | 2005-07-15 |
DE59812873D1 (de) | 2005-07-21 |
AU9154198A (en) | 1999-02-10 |
IL129065A0 (en) | 2000-02-17 |
PT1270023E (pt) | 2005-10-31 |
DE59807846D1 (de) | 2003-05-15 |
EP1270023A3 (de) | 2003-12-17 |
EP1552856A1 (de) | 2005-07-13 |
EP1270023B2 (de) | 2012-04-11 |
US7879367B2 (en) | 2011-02-01 |
JP2011031063A (ja) | 2011-02-17 |
WO1999003515A2 (de) | 1999-01-28 |
US20020004060A1 (en) | 2002-01-10 |
EP1552856B1 (de) | 2015-10-07 |
IL129065A (en) | 2006-04-10 |
ATE236667T1 (de) | 2003-04-15 |
US20110301694A1 (en) | 2011-12-08 |
WO1999003515A3 (de) | 1999-08-05 |
JP2009297537A (ja) | 2009-12-24 |
DK1270023T3 (da) | 2005-09-05 |
JP5352776B2 (ja) | 2013-11-27 |
EP1270023B1 (de) | 2005-06-15 |
IL172424A (en) | 2008-08-07 |
ES2200368T3 (es) | 2004-03-01 |
US8771751B2 (en) | 2014-07-08 |
US20110251669A1 (en) | 2011-10-13 |
EP0923389A2 (de) | 1999-06-23 |
EP0923389B1 (de) | 2003-04-09 |
DE19731021A1 (de) | 1999-01-21 |
EP1270023A2 (de) | 2003-01-02 |
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