US5866363A
(en)
*
|
1985-08-28 |
1999-02-02 |
Pieczenik; George |
Method and means for sorting and identifying biological information
|
US5824469A
(en)
*
|
1986-07-17 |
1998-10-20 |
University Of Washington |
Method for producing novel DNA sequences with biological activity
|
US20060008806A1
(en)
*
|
1986-07-17 |
2006-01-12 |
University Of Washington |
Method for producing novel DNA sequence with biological activity
|
US5266684A
(en)
|
1988-05-02 |
1993-11-30 |
The Reagents Of The University Of California |
Peptide mixtures
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
CA2009996A1
(en)
*
|
1989-02-17 |
1990-08-17 |
Kathleen S. Cook |
Process for making genes encoding random polymers of amino acids
|
US7413537B2
(en)
|
1989-09-01 |
2008-08-19 |
Dyax Corp. |
Directed evolution of disulfide-bonded micro-proteins
|
JP3127158B2
(ja)
*
|
1989-10-05 |
2001-01-22 |
オプテイン,インコーポレイティド |
新規の遺伝子及びポリペチドの無細胞合成並びに単離
|
US5747334A
(en)
*
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
US5498538A
(en)
*
|
1990-02-15 |
1996-03-12 |
The University Of North Carolina At Chapel Hill |
Totally synthetic affinity reagents
|
DE69132902D1
(de)
*
|
1990-02-15 |
2002-02-21 |
Univ North Carolina Chapel Hill |
Methoden zur identifizierung heterofunktionaler fusionsproteine
|
US5639595A
(en)
*
|
1990-05-01 |
1997-06-17 |
Isis Phamaceuticals, Inc. |
Identification of novel drugs and reagents
|
US5427908A
(en)
*
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
US6759392B1
(en)
|
1990-06-11 |
2004-07-06 |
Gilead Sciences, Inc. |
High affinity RNA ligands of basic fibroblast growth factor
|
US6083696A
(en)
*
|
1990-06-11 |
2000-07-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands exponential enrichment: blended selex
|
US6569620B1
(en)
|
1990-06-11 |
2003-05-27 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US5270163A
(en)
*
|
1990-06-11 |
1993-12-14 |
University Research Corporation |
Methods for identifying nucleic acid ligands
|
US5712375A
(en)
*
|
1990-06-11 |
1998-01-27 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5686592A
(en)
*
|
1990-06-11 |
1997-11-11 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US5496938A
(en)
|
1990-06-11 |
1996-03-05 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to HIV-RT and HIV-1 rev
|
US20040132067A1
(en)
*
|
1990-06-11 |
2004-07-08 |
Somalogic, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5580737A
(en)
*
|
1990-06-11 |
1996-12-03 |
Nexstar Pharmaceuticals, Inc. |
High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
|
US5837834A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US5763173A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5629155A
(en)
*
|
1990-06-11 |
1997-05-13 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to immunoglobulin E (IgE)
|
US5756287A
(en)
*
|
1990-06-11 |
1998-05-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV integrase inhibitors
|
US5763177A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US6127119A
(en)
*
|
1990-06-11 |
2000-10-03 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5837456A
(en)
*
|
1990-06-11 |
1998-11-17 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US5853984A
(en)
*
|
1990-06-11 |
1998-12-29 |
Nexstar Pharmaceuticals, Inc. |
Use of nucleic acid ligands in flow cytometry
|
US6346611B1
(en)
|
1990-06-11 |
2002-02-12 |
Gilead Sciences, Inc. |
High affinity TGfβ nucleic acid ligands and inhibitors
|
US5795721A
(en)
*
|
1990-06-11 |
1998-08-18 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of ICP4
|
US5693502A
(en)
*
|
1990-06-11 |
1997-12-02 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5763566A
(en)
*
|
1990-06-11 |
1998-06-09 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
US20060084797A1
(en)
*
|
1990-06-11 |
2006-04-20 |
Gilead Sciences, Inc. |
High affinity TGFbeta nucleic acid ligands and inhibitors
|
US6465188B1
(en)
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Nucleic acid ligand complexes
|
US5527894A
(en)
*
|
1990-06-11 |
1996-06-18 |
Nexstar Pharmacueticals, Inc. |
Ligands of HIV-1 tat protein
|
US5861254A
(en)
*
|
1997-01-31 |
1999-01-19 |
Nexstar Pharmaceuticals, Inc. |
Flow cell SELEX
|
US5654151A
(en)
*
|
1990-06-11 |
1997-08-05 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV Nucleocapsid nucleic acid ligands
|
US5648214A
(en)
*
|
1990-06-11 |
1997-07-15 |
University Research Corporation |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US6124449A
(en)
*
|
1990-06-11 |
2000-09-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US5811533A
(en)
*
|
1990-06-11 |
1998-09-22 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US5688935A
(en)
*
|
1990-06-11 |
1997-11-18 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US6232071B1
(en)
*
|
1990-06-11 |
2001-05-15 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
US5707796A
(en)
*
|
1990-06-11 |
1998-01-13 |
Nexstar Pharmaceuticals, Inc. |
Method for selecting nucleic acids on the basis of structure
|
US5731144A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands
|
US5789157A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US5750342A
(en)
*
|
1990-06-11 |
1998-05-12 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands of tissue target
|
US5459015A
(en)
*
|
1990-06-11 |
1995-10-17 |
Nexstar Pharmaceuticals, Inc. |
High-affinity RNA ligands of basic fibroblast growth factor
|
US6465189B1
(en)
*
|
1990-06-11 |
2002-10-15 |
Gilead Sciences, Inc. |
Systematic evolution of ligands by exponential enrichment: blended selex
|
US5789163A
(en)
*
|
1990-06-11 |
1998-08-04 |
Nexstar Pharmaceuticals, Inc. |
Enzyme linked oligonucleotide assays (ELONAS)
|
US6011020A
(en)
*
|
1990-06-11 |
2000-01-04 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand complexes
|
US5683867A
(en)
*
|
1990-06-11 |
1997-11-04 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: blended SELEX
|
US5972599A
(en)
*
|
1990-06-11 |
1999-10-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
US5962219A
(en)
|
1990-06-11 |
1999-10-05 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-selex
|
US6140490A
(en)
*
|
1996-02-01 |
2000-10-31 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US6261774B1
(en)
|
1990-06-11 |
2001-07-17 |
Gilead Sciences, Inc. |
Truncation selex method
|
US5766853A
(en)
*
|
1990-06-11 |
1998-06-16 |
Nexstar Pharmaceuticals, Inc. |
Method for identification of high affinity nucleic acid ligands to selectins
|
US5660985A
(en)
|
1990-06-11 |
1997-08-26 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands containing modified nucleotides
|
US5668264A
(en)
*
|
1990-06-11 |
1997-09-16 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US6344321B1
(en)
*
|
1990-06-11 |
2002-02-05 |
Gilead Sciences, Inc. |
Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
|
US5543293A
(en)
*
|
1990-06-11 |
1996-08-06 |
Nexstar Pharmaceuticals, Inc. |
DNA ligands of thrombin
|
US5726017A
(en)
*
|
1990-06-11 |
1998-03-10 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV-1 gag nucleic acid ligands
|
US5780228A
(en)
*
|
1990-06-11 |
1998-07-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US6395888B1
(en)
|
1996-02-01 |
2002-05-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands of complement system proteins
|
US5846713A
(en)
*
|
1990-06-11 |
1998-12-08 |
Nexstar Pharmaceuticals, Inc. |
High affinity HKGF nucleic acid ligands and inhibitors
|
US5869641A
(en)
*
|
1990-06-11 |
1999-02-09 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of CD4
|
US6610841B1
(en)
|
1997-12-18 |
2003-08-26 |
Gilead Sciences, Inc. |
Nucleotide-based prodrugs
|
US5472841A
(en)
*
|
1990-06-11 |
1995-12-05 |
Nexstar Pharmaceuticals, Inc. |
Methods for identifying nucleic acid ligands of human neutrophil elastase
|
US5705337A
(en)
*
|
1990-06-11 |
1998-01-06 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US5503978A
(en)
*
|
1990-06-11 |
1996-04-02 |
University Research Corporation |
Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
|
ATE318832T1
(de)
*
|
1990-06-11 |
2006-03-15 |
Gilead Sciences Inc |
Verfahren zur vervendung von nukleinsäureliganden
|
US5874557A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligand inhibitors to DNA polymerases
|
US6716580B2
(en)
|
1990-06-11 |
2004-04-06 |
Somalogic, Inc. |
Method for the automated generation of nucleic acid ligands
|
US5849890A
(en)
*
|
1990-06-11 |
1998-12-15 |
Nexstar Pharmaceuticals, Inc. |
High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones
|
US6001988A
(en)
*
|
1990-06-11 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands to lectins
|
US5637682A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to the tachykinin substance P
|
US5637459A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
US5674685A
(en)
*
|
1990-06-11 |
1997-10-07 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US5723289A
(en)
*
|
1990-06-11 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
Parallel selex
|
US6177557B1
(en)
|
1990-06-11 |
2001-01-23 |
Nexstar Pharmaceuticals, Inc. |
High affinity ligands of basic fibroblast growth factor and thrombin
|
US5731424A
(en)
*
|
1990-06-11 |
1998-03-24 |
Nexstar Pharmaceuticals, Inc. |
High affinity TGFβ nucleic acid ligands and inhibitors
|
US5587468A
(en)
*
|
1990-06-11 |
1996-12-24 |
University Research Corporation |
High affinity nucleic acid ligands to HIV integrase
|
US6030776A
(en)
*
|
1990-06-11 |
2000-02-29 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX
|
US5864026A
(en)
*
|
1990-06-11 |
1999-01-26 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US6280932B1
(en)
|
1990-06-11 |
2001-08-28 |
Gilead Sciences, Inc. |
High affinity nucleic acid ligands to lectins
|
US6001577A
(en)
*
|
1998-06-08 |
1999-12-14 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
|
US5641629A
(en)
*
|
1990-06-11 |
1997-06-24 |
Nexstar Pharmacueticals Inc |
Spectroscopically detectable nucleic acid ligands
|
US5635615A
(en)
*
|
1990-06-11 |
1997-06-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity HIV nucleocapsid nucleic acid ligands
|
US6696252B2
(en)
|
1990-06-11 |
2004-02-24 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US5874218A
(en)
*
|
1990-06-11 |
1999-02-23 |
Nexstar Pharmaceuticals, Inc. |
Method for detecting a target compound in a substance using a nucleic acid ligand
|
US5567588A
(en)
*
|
1990-06-11 |
1996-10-22 |
University Research Corporation |
Systematic evolution of ligands by exponential enrichment: Solution SELEX
|
US6331394B1
(en)
|
1991-06-10 |
2001-12-18 |
Gilead Sciences, Inc. |
Nucleic acid ligands to integrins
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
US7063943B1
(en)
|
1990-07-10 |
2006-06-20 |
Cambridge Antibody Technology |
Methods for producing members of specific binding pairs
|
US6916605B1
(en)
*
|
1990-07-10 |
2005-07-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
US5843701A
(en)
*
|
1990-08-02 |
1998-12-01 |
Nexstar Pharmaceticals, Inc. |
Systematic polypeptide evolution by reverse translation
|
DK1279731T3
(da)
|
1991-03-01 |
2007-09-24 |
Dyax Corp |
Fremgangsmåde til udvikling af bindende miniproteiner
|
US6762290B1
(en)
|
1999-07-29 |
2004-07-13 |
Gilead Sciences, Inc. |
High affinity vascular endothelial growth factor (VEGF) receptor nucleic acid ligands and inhibitors
|
AU732820B2
(en)
|
1995-06-02 |
2001-05-03 |
Nexstar Pharmaceuticals, Inc. |
High-affinity oligonucleotide ligands to growth factors
|
US6028186A
(en)
*
|
1991-06-10 |
2000-02-22 |
Nexstar Pharmaceuticals, Inc. |
High affinity nucleic acid ligands of cytokines
|
AU2313392A
(en)
*
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
US5733731A
(en)
*
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
US5270170A
(en)
*
|
1991-10-16 |
1993-12-14 |
Affymax Technologies N.V. |
Peptide library and screening method
|
ES2227512T3
(es)
*
|
1991-12-02 |
2005-04-01 |
Medical Research Council |
Produccion de anticuerpos contra auto-antigenos a partir de repertorios de segmentos de anticuerpos fijados en un fago.
|
US5656467A
(en)
*
|
1992-01-09 |
1997-08-12 |
The Trustees Of The University Of Pennsylvania |
Methods and materials for producing gene libraries
|
CA2132306C
(en)
*
|
1992-03-16 |
2012-07-10 |
Jacob N. Wohlstadter |
Selection methods
|
US5869644A
(en)
*
|
1992-04-15 |
1999-02-09 |
The Johns Hopkins University |
Synthesis of diverse and useful collections of oligonucleotidies
|
US5719273A
(en)
*
|
1993-06-14 |
1998-02-17 |
Nexstar Pharmaceuticals, Inc. |
Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
|
US5998142A
(en)
*
|
1993-09-08 |
1999-12-07 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chemi-SELEX
|
US6458539B1
(en)
|
1993-09-17 |
2002-10-01 |
Somalogic, Inc. |
Photoselection of nucleic acid ligands
|
CA2173990A1
(en)
*
|
1993-10-12 |
1995-04-20 |
Narasinga Rao |
A library of glyco-peptides useful for identification of cell adhesion inhibitors
|
US20060078561A1
(en)
*
|
1994-01-31 |
2006-04-13 |
The Trustees Of Boston University |
Polyclonal antibody libraries
|
PT744958E
(pt)
|
1994-01-31 |
2003-11-28 |
Univ Boston |
Bancos de anticorpos policlonais
|
US6395547B1
(en)
|
1994-02-17 |
2002-05-28 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6335160B1
(en)
*
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US5605793A
(en)
*
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US6406855B1
(en)
|
1994-02-17 |
2002-06-18 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6309883B1
(en)
*
|
1994-02-17 |
2001-10-30 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US20060257890A1
(en)
|
1996-05-20 |
2006-11-16 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
US6117679A
(en)
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US7153948B2
(en)
|
1994-04-25 |
2006-12-26 |
Gilead Sciences, Inc. |
High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF)
|
US6682886B1
(en)
|
1994-04-28 |
2004-01-27 |
Gilead Sciences, Inc. |
Bivalent binding molecules of 7 transmembrane G protein-coupled receptors
|
US6010861A
(en)
*
|
1994-08-03 |
2000-01-04 |
Dgi Biotechnologies, Llc |
Target specific screens and their use for discovering small organic molecular pharmacophores
|
US6048698A
(en)
*
|
1994-09-20 |
2000-04-11 |
Nexstar Pharmaceuticals, Inc. |
Parallel SELEX™
|
CA2200684A1
(en)
*
|
1994-09-21 |
1996-03-28 |
Cytogen Corporation |
Antigen binding peptides (abtides) from peptide libraries
|
US5885577A
(en)
*
|
1994-09-21 |
1999-03-23 |
Cytogen Corporation |
Antigen binding peptides (abtides) from peptide libraries
|
AU732961B2
(en)
*
|
1995-05-03 |
2001-05-03 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue selex
|
US6013443A
(en)
*
|
1995-05-03 |
2000-01-11 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: tissue SELEX
|
US5859228A
(en)
*
|
1995-05-04 |
1999-01-12 |
Nexstar Pharmaceuticals, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
US8071737B2
(en)
|
1995-05-04 |
2011-12-06 |
Glead Sciences, Inc. |
Nucleic acid ligand complexes
|
US5723594A
(en)
*
|
1995-06-07 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
High affinity PDGF nucleic acid ligands
|
US20010053523A1
(en)
*
|
1995-06-02 |
2001-12-20 |
M&E Biotech A/S. |
Method for identification of biologically active peptides and nucleic acids
|
EP2080813B1
(de)
*
|
1995-06-07 |
2011-01-05 |
Gilead Sciences, Inc. |
Nukleinsäureliganden, die an DNA-Polymerasen binden und diese inhibieren
|
US5797870A
(en)
*
|
1995-06-07 |
1998-08-25 |
Indiana University Foundation |
Pericardial delivery of therapeutic and diagnostic agents
|
US6475806B1
(en)
|
1995-06-07 |
2002-11-05 |
Praecis Pharmaceuticals, Inc. |
Anchor libraries and identification of peptide binding sequences
|
US6699843B2
(en)
|
1995-06-07 |
2004-03-02 |
Gilead Sciences, Inc. |
Method for treatment of tumors using nucleic acid ligands to PDGF
|
US6229002B1
(en)
|
1995-06-07 |
2001-05-08 |
Nexstar Pharmaceuticlas, Inc. |
Platelet derived growth factor (PDGF) nucleic acid ligand complexes
|
US20090118481A1
(en)
*
|
1995-06-07 |
2009-05-07 |
Gilead Sciences, Inc. |
High Affinity Nucleic Acid Ligands To Lectins
|
US6183967B1
(en)
|
1995-06-07 |
2001-02-06 |
Nexstar Pharmaceuticals |
Nucleic acid ligand inhibitors to DNA polymerases
|
US5830696A
(en)
|
1996-12-05 |
1998-11-03 |
Diversa Corporation |
Directed evolution of thermophilic enzymes
|
US6939689B2
(en)
|
1995-12-07 |
2005-09-06 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US6352842B1
(en)
|
1995-12-07 |
2002-03-05 |
Diversa Corporation |
Exonucease-mediated gene assembly in directed evolution
|
US5965408A
(en)
|
1996-07-09 |
1999-10-12 |
Diversa Corporation |
Method of DNA reassembly by interrupting synthesis
|
US6358709B1
(en)
|
1995-12-07 |
2002-03-19 |
Diversa Corporation |
End selection in directed evolution
|
US6537776B1
(en)
*
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US6713279B1
(en)
|
1995-12-07 |
2004-03-30 |
Diversa Corporation |
Non-stochastic generation of genetic vaccines and enzymes
|
US20030219752A1
(en)
*
|
1995-12-07 |
2003-11-27 |
Diversa Corporation |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof
|
US20020028443A1
(en)
*
|
1999-09-27 |
2002-03-07 |
Jay M. Short |
Method of dna shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process
|
US20020164580A1
(en)
*
|
1995-12-07 |
2002-11-07 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
US6740506B2
(en)
|
1995-12-07 |
2004-05-25 |
Diversa Corporation |
End selection in directed evolution
|
US6361974B1
(en)
|
1995-12-07 |
2002-03-26 |
Diversa Corporation |
Exonuclease-mediated nucleic acid reassembly in directed evolution
|
US7018793B1
(en)
|
1995-12-07 |
2006-03-28 |
Diversa Corporation |
Combinatorial screening of mixed populations of organisms
|
JP2000504220A
(ja)
|
1996-01-23 |
2000-04-11 |
ライガル ファーマシューティカルズ インコーポレイテッド |
トランス支配性細胞内作用因子ペプチドおよびrna分子のスクリーニング方法
|
US6365344B1
(en)
*
|
1996-01-23 |
2002-04-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for screening for transdominant effector peptides and RNA molecules
|
US6096548A
(en)
|
1996-03-25 |
2000-08-01 |
Maxygen, Inc. |
Method for directing evolution of a virus
|
US6506602B1
(en)
|
1996-03-25 |
2003-01-14 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6300065B1
(en)
|
1996-05-31 |
2001-10-09 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6696251B1
(en)
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6838238B1
(en)
|
1996-10-17 |
2005-01-04 |
Invitrogen Corporation |
Morphatides: novel shape and structure libraries
|
US6426335B1
(en)
*
|
1997-10-17 |
2002-07-30 |
Gilead Sciences, Inc. |
Vascular endothelial growth factor (VEGF) nucleic acid ligand complexes
|
US6355426B2
(en)
|
1996-10-31 |
2002-03-12 |
Smithkline Beecham Corporation |
Methods for the characterization and selection of RNA target motifs that bind compounds of pharmaceutical use
|
US20070009930A1
(en)
*
|
1996-12-18 |
2007-01-11 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
AU743305C
(en)
|
1997-01-17 |
2006-03-30 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
US7148054B2
(en)
|
1997-01-17 |
2006-12-12 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
US6326204B1
(en)
|
1997-01-17 |
2001-12-04 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
WO1998031700A1
(en)
|
1997-01-21 |
1998-07-23 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
US8207093B2
(en)
*
|
1997-01-21 |
2012-06-26 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US5871924A
(en)
*
|
1997-01-27 |
1999-02-16 |
Nexstar Pharmaceuticals, Inc. |
Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
US6180341B1
(en)
|
1997-05-01 |
2001-01-30 |
Board Of Regents, The Universiry Of Texas System |
In vitro scanning saturation mutagenesis of proteins
|
US7087420B1
(en)
|
1997-07-17 |
2006-08-08 |
Cambia |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6391547B1
(en)
*
|
1997-09-09 |
2002-05-21 |
Center For The Application Of Molecular Biology To International Agriculture |
Microbial β-glucuronidase genes, gene products and uses thereof
|
US6241701B1
(en)
|
1997-08-01 |
2001-06-05 |
Genetronics, Inc. |
Apparatus for electroporation mediated delivery of drugs and genes
|
US6670127B2
(en)
|
1997-09-16 |
2003-12-30 |
Egea Biosciences, Inc. |
Method for assembly of a polynucleotide encoding a target polypeptide
|
US6596539B1
(en)
|
1997-10-31 |
2003-07-22 |
Maxygen, Inc. |
Modification of virus tropism and host range by viral genome shuffling
|
IL136574A0
(en)
*
|
1997-12-08 |
2001-06-14 |
California Inst Of Techn |
A method for forming a polynucleotide of desired properties
|
US20030219803A1
(en)
*
|
1997-12-15 |
2003-11-27 |
Somalogic, Incorporated |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US20070166741A1
(en)
|
1998-12-14 |
2007-07-19 |
Somalogic, Incorporated |
Multiplexed analyses of test samples
|
US6261783B1
(en)
|
1997-12-15 |
2001-07-17 |
Gilead Sciences, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US5989823A
(en)
*
|
1998-09-18 |
1999-11-23 |
Nexstar Pharmaceuticals, Inc. |
Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
|
US6759243B2
(en)
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
US6541011B2
(en)
|
1998-02-11 |
2003-04-01 |
Maxygen, Inc. |
Antigen library immunization
|
US7390619B1
(en)
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
FR2782325B1
(fr)
|
1998-08-12 |
2002-05-24 |
Proteus |
Procede d'identification de sequences polynucleotidiques et/ou des proteines correspondantes a partir d'un echantillon d'acides nucleiques
|
US7157083B2
(en)
*
|
1998-04-17 |
2007-01-02 |
Surrogate Pharmaceutical Pathways, Llc |
Compositions and methods for treating retroviral infections
|
US6500617B1
(en)
|
1998-05-01 |
2002-12-31 |
Maxygen, Inc. |
Optimization of pest resistance genes using DNA shuffling
|
US7153655B2
(en)
*
|
1998-06-16 |
2006-12-26 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
|
US6365408B1
(en)
|
1998-06-19 |
2002-04-02 |
Maxygen, Inc. |
Methods of evolving a polynucleotides by mutagenesis and recombination
|
AU5122499A
(en)
|
1998-07-27 |
2000-02-21 |
Genentech Inc. |
Improved transformation efficiency in phage display through modification of a coat protein
|
EP1105360B1
(de)
|
1998-08-17 |
2009-07-29 |
Bristol-Myers Squibb Company |
Identifizierung von verbindung-protein wechselwirkungen mit bibliotheken von gekoppelten protein-nukleinsäure-molekülen
|
US6773911B1
(en)
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
US6570003B1
(en)
*
|
2001-01-09 |
2003-05-27 |
Lexion Genetics Incorporated |
Human 7TM proteins and polynucleotides encoding the same
|
WO2000040715A2
(en)
*
|
1999-01-05 |
2000-07-13 |
Trustees Of Boston University |
Improved nucleic acid cloning
|
EP1151409A1
(de)
*
|
1999-01-18 |
2001-11-07 |
Maxygen, Inc. |
Verfahren zum bevölkern von datenstrukturen für evolutionäre-simulationen
|
US20030054390A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
US20030054360A1
(en)
*
|
1999-01-19 |
2003-03-20 |
Larry Gold |
Method and apparatus for the automated generation of nucleic acid ligands
|
US20070065838A1
(en)
*
|
1999-01-19 |
2007-03-22 |
Maxygen, Inc. |
Oligonucleotide mediated nucleic acid recombination
|
US20090130718A1
(en)
*
|
1999-02-04 |
2009-05-21 |
Diversa Corporation |
Gene site saturation mutagenesis
|
US6329145B1
(en)
|
1999-02-09 |
2001-12-11 |
Gilead Science, Inc. |
Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligand
|
AU3719500A
(en)
|
1999-03-05 |
2000-09-21 |
Maxygen, Inc. |
Recombination of insertion modified nucleic acids
|
US6703240B1
(en)
|
1999-04-13 |
2004-03-09 |
Maxygar, Inc. |
Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
|
US7332308B1
(en)
|
1999-05-21 |
2008-02-19 |
The Penn State Research Foundation |
Incrementally truncated nucleic acids and methods of making same
|
US6280943B1
(en)
|
1999-06-17 |
2001-08-28 |
Gilead Sciences, Inc. |
2′-fluoropyrimidine anti-calf intestinal phosphatase nucleic acid ligands
|
IL147336A0
(en)
|
1999-07-07 |
2002-08-14 |
Zymogenetics Inc |
Human cytokine receptor
|
US6387620B1
(en)
*
|
1999-07-28 |
2002-05-14 |
Gilead Sciences, Inc. |
Transcription-free selex
|
US6171795B1
(en)
|
1999-07-29 |
2001-01-09 |
Nexstar Pharmaceuticals, Inc. |
Nucleic acid ligands to CD40ligand
|
US7005260B1
(en)
|
2000-01-28 |
2006-02-28 |
Gilead Sciences, Inc. |
Tenascin-C nucleic acid ligands
|
US6506887B1
(en)
|
1999-07-29 |
2003-01-14 |
Somalogic, Incorporated |
Conditional-selex
|
ATE428719T1
(de)
*
|
1999-07-29 |
2009-05-15 |
Gilead Sciences Inc |
Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors
|
US6797510B1
(en)
*
|
2001-05-24 |
2004-09-28 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6593125B2
(en)
|
2000-11-20 |
2003-07-15 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6900045B2
(en)
*
|
2000-08-31 |
2005-05-31 |
Lexicon Genetics Incorporated |
Human kinase proteins and polynucleotides encoding the same
|
US20080050809A1
(en)
*
|
1999-09-28 |
2008-02-28 |
Alejandro Abuin |
Novel human kinases and polynucleotides encoding the same
|
US6734010B2
(en)
*
|
2001-05-09 |
2004-05-11 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6586230B1
(en)
|
2000-10-27 |
2003-07-01 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6841377B1
(en)
*
|
2001-06-13 |
2005-01-11 |
Lexicon Genetics Incorporated |
Human kinase and polynucleotides encoding the same
|
US6579710B2
(en)
*
|
2000-12-12 |
2003-06-17 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6541252B1
(en)
|
2000-05-19 |
2003-04-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
EP1240319A1
(de)
*
|
1999-12-15 |
2002-09-18 |
Genentech, Inc. |
"shotgun scanning", eine methode zur kartierung von funktionellen protein epitopen
|
US7022479B2
(en)
*
|
2000-01-24 |
2006-04-04 |
Compound Therapeutics, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
CA2396810A1
(en)
|
2000-01-24 |
2001-07-26 |
Phylos, Inc. |
Sensitive, multiplexed diagnostic assays for protein analysis
|
US20020077464A1
(en)
*
|
2000-01-26 |
2002-06-20 |
Turner C. Alexander |
Novel human neurexin-like proteins and polynucleotides encoding the same
|
US20050239061A1
(en)
*
|
2000-03-01 |
2005-10-27 |
Marshall William S |
Identification and use of effectors and allosteric molecules for the alteration of gene expression
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
AU2001289284A1
(en)
*
|
2000-04-04 |
2001-10-15 |
Enanta Pharmaceuticals, Inc. |
Methods for identifying peptide aptamers capable of altering a cell phenotype
|
DK2199393T3
(da)
*
|
2000-04-17 |
2012-11-26 |
Dyax Corp |
Hidtil ukendte fremgangsmåder til opbygning af biblioteker over genetiske pakker, der kollektivt viser medlemmerne af en forskelligartet familie af peptider, polypeptider eller proteiner
|
US8288322B2
(en)
|
2000-04-17 |
2012-10-16 |
Dyax Corp. |
Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
|
WO2001079562A1
(en)
*
|
2000-04-18 |
2001-10-25 |
Gilead Sciences, Inc. |
Aptamer based two-site binding assay
|
US6479262B1
(en)
|
2000-05-16 |
2002-11-12 |
Hercules, Incorporated |
Solid phase enzymatic assembly of polynucleotides
|
WO2001090179A2
(en)
*
|
2000-05-23 |
2001-11-29 |
Lexicon Genetics Incorporated |
Novel human thrombospondin-like proteins and polynucleotides encoding the same
|
AU2001275337A1
(en)
*
|
2000-06-07 |
2001-12-17 |
Lexicon Genetics Incorporated |
Novel human transporter proteins and polynucleotides encoding the same
|
WO2001094417A2
(en)
*
|
2000-06-09 |
2001-12-13 |
Lexicon Genetics Incorporated |
Novel human seven transmembrane proteins and polynucleotides encoding the same
|
US6465632B1
(en)
|
2000-06-09 |
2002-10-15 |
Lexicon Genetics Incorporated |
Human phosphatases and polynucleotides encoding the same
|
MXPA02012747A
(es)
|
2000-06-28 |
2003-09-25 |
Amgen Inc |
Moleculas del receptor de linfopoietina estromica timica y sus usos.
|
US6994963B1
(en)
|
2000-07-10 |
2006-02-07 |
Ambion, Inc. |
Methods for recombinatorial nucleic acid synthesis
|
JP2004504330A
(ja)
*
|
2000-07-13 |
2004-02-12 |
インヴィトロジェン コーポレーション |
溶解マトリクスを用いてタンパク質およびペプチドの迅速な抽出および単離のための方法および組成物
|
WO2002008408A2
(en)
*
|
2000-07-21 |
2002-01-31 |
Trustees Of Boston University |
Modular vector systems
|
US7087415B2
(en)
*
|
2000-07-31 |
2006-08-08 |
Athena Biotechnologies, Inc. |
Methods and compositions for directed gene assembly
|
WO2002011748A1
(en)
*
|
2000-08-07 |
2002-02-14 |
Sloan-Kettering Institute For Cancer Research |
Method and composition for immunization using mixed pools of mutated nucleic acids or peptides
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
AU2001286792A1
(en)
*
|
2000-08-22 |
2002-03-04 |
Lexicon Genetics Incorporated |
Novel human 7TM proteins and polynucleotides encoding the same
|
US6376190B1
(en)
|
2000-09-22 |
2002-04-23 |
Somalogic, Inc. |
Modified SELEX processes without purified protein
|
EP2322648A1
(de)
*
|
2000-09-26 |
2011-05-18 |
Duke University |
RNA-Aptamere und Verfahren zu ihrer Identifizierung
|
WO2002031745A1
(en)
*
|
2000-10-10 |
2002-04-18 |
Genencor International, Inc. |
Information rich libraries
|
WO2002033116A2
(en)
|
2000-10-16 |
2002-04-25 |
Gilead Sciences, Inc. |
Nucleic acid ligands to the prostate specific membrane antigen
|
JP2004533221A
(ja)
*
|
2000-10-27 |
2004-11-04 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒト7tmタンパクおよびそれをコードするポリヌクレオチド
|
EP1330524A2
(de)
*
|
2000-10-30 |
2003-07-30 |
Lexicon Genetics Incorporated |
Humane 7tm-proteine und dafür kodierende polynukleotiden
|
AU2002220275A1
(en)
*
|
2000-12-08 |
2002-06-18 |
The Board Of Trustees Of The University Of Illinois |
Mutated class ii major histocompatibility proteins
|
JP2004517622A
(ja)
*
|
2000-12-11 |
2004-06-17 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
|
US6958213B2
(en)
|
2000-12-12 |
2005-10-25 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function
|
AU2002249854B2
(en)
|
2000-12-18 |
2007-09-20 |
Dyax Corp. |
Focused libraries of genetic packages
|
US6852844B1
(en)
|
2000-12-20 |
2005-02-08 |
Lexicon Genetics Incorporated |
Human protocadherin proteins and polynucleotides encoding the same
|
US20020086292A1
(en)
|
2000-12-22 |
2002-07-04 |
Shigeaki Harayama |
Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
|
JP4986370B2
(ja)
|
2000-12-22 |
2012-07-25 |
マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ |
Rgmおよびそのモジュレーターの用途
|
WO2002059325A2
(en)
*
|
2000-12-27 |
2002-08-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
JP4061043B2
(ja)
|
2000-12-28 |
2008-03-12 |
株式会社ポストゲノム研究所 |
invitro転写/翻訳系によるペプチド等の製造方法
|
WO2002059287A2
(en)
*
|
2001-01-23 |
2002-08-01 |
Lexicon Genetics Incorporated |
Novel human kinases and polynucleotides encoding the same
|
JP4689940B2
(ja)
*
|
2001-02-02 |
2011-06-01 |
ノビシ バイオテック,リミティド ライアビリティ カンパニー |
ヘテロ二本鎖の相補性を増大させる方法
|
US7582423B2
(en)
*
|
2001-02-02 |
2009-09-01 |
Novici Biotech Llc |
Population of polynucleotide sequence variants
|
US20040142433A1
(en)
*
|
2001-02-02 |
2004-07-22 |
Padgett Hal S. |
Polynucleotide sequence variants
|
US7838219B2
(en)
*
|
2001-02-02 |
2010-11-23 |
Novici Biotech Llc |
Method of increasing complementarity in a heteroduplex
|
WO2002065125A1
(en)
*
|
2001-02-13 |
2002-08-22 |
Invitrogen Corporation |
Methods and compositions for isolation of biological macromolecules
|
EP1373496A4
(de)
*
|
2001-02-22 |
2004-10-27 |
Praecis Pharm Inc |
Verfahren zur identifizierung von einen biologischen vorgang modulierenden peptiden
|
JP2004532624A
(ja)
|
2001-03-02 |
2004-10-28 |
ザイモジェネティクス,インコーポレイティド |
マウスサイトカイン受容体
|
AU2002257076A1
(en)
|
2001-03-19 |
2002-10-03 |
President And Fellows Of Harvard College |
Nucleic acid shuffling
|
US7807408B2
(en)
*
|
2001-03-19 |
2010-10-05 |
President & Fellows Of Harvard College |
Directed evolution of proteins
|
WO2002074932A2
(en)
|
2001-03-20 |
2002-09-26 |
Lexicon Genetics Incorporated |
Novel human kinase and polynucleotides encoding the same
|
JP2004524043A
(ja)
|
2001-04-06 |
2004-08-12 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼ及び該キナーゼをコードするポリヌクレオチド
|
JP2004528841A
(ja)
*
|
2001-04-06 |
2004-09-24 |
レキシコン・ジェネティクス・インコーポレーテッド |
新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
|
US6644173B2
(en)
*
|
2001-04-11 |
2003-11-11 |
Keuring, Incorporated |
Beverage filter cartridge holder
|
WO2002090496A2
(en)
*
|
2001-05-03 |
2002-11-14 |
Rensselaer Polytechnic Institute |
Novel methods of directed evolution
|
WO2002097095A1
(en)
*
|
2001-05-25 |
2002-12-05 |
Lexicon Genetics Incorporated |
Novel human transporter proteins and polynucleotides encoding the same
|
PT2070939E
(pt)
|
2001-05-25 |
2014-06-09 |
Univ Duke |
Moduladores de agentes farmacológicos
|
CA2448347C
(en)
|
2001-05-29 |
2010-09-21 |
Lexicon Genetics Incorporated |
Novel human hydroxylases and polynucleotides encoding the same
|
US20030113714A1
(en)
*
|
2001-09-28 |
2003-06-19 |
Belcher Angela M. |
Biological control of nanoparticles
|
US20050164515A9
(en)
*
|
2001-06-05 |
2005-07-28 |
Belcher Angela M. |
Biological control of nanoparticle nucleation, shape and crystal phase
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
US20030148380A1
(en)
*
|
2001-06-05 |
2003-08-07 |
Belcher Angela M. |
Molecular recognition of materials
|
CA2633171C
(en)
|
2001-06-20 |
2012-11-20 |
Genentech, Inc. |
Antibodies against tumor-associated antigenic target (tat) polypeptides
|
DE10131441A1
(de)
*
|
2001-06-29 |
2003-01-30 |
Henkel Kgaa |
Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen
|
US20040204669A1
(en)
*
|
2001-07-05 |
2004-10-14 |
Hofmann Gunter A. |
Apparatus for electroporation mediated delivery for drugs and genes
|
EP1493028A4
(de)
*
|
2001-07-06 |
2006-06-14 |
Genentech Inc |
Im phagen-display präsentierte liganden der pdz-domäne
|
US6943001B2
(en)
*
|
2001-08-03 |
2005-09-13 |
Diversa Corporation |
Epoxide hydrolases, nucleic acids encoding them and methods for making and using them
|
JP2005508619A
(ja)
*
|
2001-08-03 |
2005-04-07 |
ディヴァーサ コーポレイション |
エポキシドヒドロラーゼ、それらをコードした核酸及びそれらの作製法と利用法
|
DE10138753B4
(de)
*
|
2001-08-07 |
2017-07-20 |
Henkel Ag & Co. Kgaa |
Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
|
US7647184B2
(en)
*
|
2001-08-27 |
2010-01-12 |
Hanall Pharmaceuticals, Co. Ltd |
High throughput directed evolution by rational mutagenesis
|
CA2460120A1
(en)
|
2001-09-18 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
AU2002330162B2
(en)
|
2001-10-01 |
2008-08-07 |
Takeda Pharmaceutical Company Limited |
Multi-chain eukaryotic display vectors and uses thereof
|
US20030073104A1
(en)
*
|
2001-10-02 |
2003-04-17 |
Belcher Angela M. |
Nanoscaling ordering of hybrid materials using genetically engineered mesoscale virus
|
EP1840211A1
(de)
|
2001-10-31 |
2007-10-03 |
Danisco A/S |
Pyranoson Dehydratase aus phanerochaete Chrysosporium
|
ES2624547T3
(es)
|
2001-11-14 |
2017-07-14 |
Janssen Biotech, Inc. |
Anticuerpos anti il 6, composiciones, métodos y usos
|
ES2327398T3
(es)
*
|
2001-11-20 |
2009-10-29 |
Duke University |
Biomateriales interfaciales.
|
AU2002366523A1
(en)
*
|
2001-12-05 |
2003-06-23 |
E-Tenna Corporation |
Capacitively-loaded bent-wire monopole on an artificial magnetic conductor
|
US7179907B2
(en)
|
2001-12-18 |
2007-02-20 |
Bruce Eaton |
Antibiotic compounds
|
WO2003057921A1
(en)
*
|
2001-12-26 |
2003-07-17 |
Sloan Kettering Institute For Cancer Research |
Dna immunization with libraries of minigenes encoding degenerate variants of major histocompatibility class i restricted epitopes
|
KR20080106369A
(ko)
|
2002-01-02 |
2008-12-04 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
WO2003064612A2
(en)
*
|
2002-01-28 |
2003-08-07 |
Sloan-Kettering Institute For Cancer Research |
Identification of mutant antigens with enhanced immunogenicity
|
US7078211B2
(en)
*
|
2002-02-01 |
2006-07-18 |
Large Scale Biology Corporation |
Nucleic acid molecules encoding endonucleases and methods of use thereof
|
US20030157495A1
(en)
*
|
2002-02-01 |
2003-08-21 |
Padgett Hal S. |
Nucleic acid molecules encoding CEL I endonuclease and methods of use thereof
|
AU2003217379A1
(en)
|
2002-02-15 |
2003-09-09 |
Somalogic, Inc. |
Methods and reagents for detecting target binding by nucleic acid ligands
|
US7662924B2
(en)
*
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
WO2003072738A2
(en)
*
|
2002-02-22 |
2003-09-04 |
Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
US20030224404A1
(en)
*
|
2002-02-25 |
2003-12-04 |
Manuel Vega |
High throughput directed evolution of nucleic acids by rational mutagenesis
|
US20030166010A1
(en)
*
|
2002-02-25 |
2003-09-04 |
Affholter Joseph A. |
Custom ligand design for biomolecular filtration and purification for bioseperation
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
KR20040101502A
(ko)
|
2002-04-16 |
2004-12-02 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
US7226771B2
(en)
|
2002-04-19 |
2007-06-05 |
Diversa Corporation |
Phospholipases, nucleic acids encoding them and methods for making and using them
|
CN102174546A
(zh)
|
2002-04-19 |
2011-09-07 |
维莱尼姆公司 |
磷脂酶,编码磷脂酶的核酸以及制备和应用磷脂酶的方法
|
US7262012B2
(en)
*
|
2002-05-17 |
2007-08-28 |
Alligator Bioscience Ab |
Method for in vitro molecular evolution of protein function using varied exonuclease digestion in two polynucleotide populations
|
NZ556507A
(en)
*
|
2002-06-03 |
2010-03-26 |
Genentech Inc |
Synthetic antibody phage libraries
|
EP1558741B1
(de)
*
|
2002-06-14 |
2008-02-20 |
Dyax Corporation |
Rekombination von nukleinsäurebibliotheksmitgliedern
|
JP2005533794A
(ja)
*
|
2002-06-18 |
2005-11-10 |
アーケミックス コーポレイション |
アプタマー−毒素分子およびこれを使用する方法
|
AU2003261264B2
(en)
|
2002-07-25 |
2008-12-11 |
Archemix Corp. |
Regulated aptamer therapeutics
|
EP1576151A4
(de)
|
2002-08-06 |
2006-05-17 |
Verdia Inc |
Ap1-aminoxidase-varianten
|
US20040067532A1
(en)
*
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
US20050202438A1
(en)
*
|
2002-09-09 |
2005-09-15 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
WO2004022593A2
(en)
*
|
2002-09-09 |
2004-03-18 |
Nautilus Biotech |
Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
|
US20060020396A1
(en)
*
|
2002-09-09 |
2006-01-26 |
Rene Gantier |
Rational directed protein evolution using two-dimensional rational mutagenesis scanning
|
US9303262B2
(en)
|
2002-09-17 |
2016-04-05 |
Archemix Llc |
Methods for identifying aptamer regulators
|
US20050064508A1
(en)
*
|
2003-09-22 |
2005-03-24 |
Semzyme |
Peptide mediated synthesis of metallic and magnetic materials
|
EP3502133A1
(de)
|
2002-09-27 |
2019-06-26 |
Xencor, Inc. |
Optimierte fc-varianten und verfahren zu deren erzeugung
|
JP3447009B1
(ja)
*
|
2002-10-29 |
2003-09-16 |
實 平垣 |
構築物用構成体およびその製造方法
|
US20050124565A1
(en)
*
|
2002-11-21 |
2005-06-09 |
Diener John L. |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
JP2006516151A
(ja)
*
|
2002-11-21 |
2006-06-22 |
アーケミックス コーポレイション |
改良された薬力学的特性を有する多価アプタマー治療剤ならびにそれらの作製方法および使用法
|
US8853376B2
(en)
|
2002-11-21 |
2014-10-07 |
Archemix Llc |
Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
|
US10100316B2
(en)
|
2002-11-21 |
2018-10-16 |
Archemix Llc |
Aptamers comprising CPG motifs
|
US20040197804A1
(en)
*
|
2002-12-03 |
2004-10-07 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
US20050037394A1
(en)
*
|
2002-12-03 |
2005-02-17 |
Keefe Anthony D. |
Method for in vitro selection of 2'-substituted nucleic acids
|
CA2509568A1
(en)
*
|
2002-12-26 |
2004-07-15 |
Applied Research Systems Ars Holding N.V. |
Spliced variants of lgr6
|
EP1585767A2
(de)
*
|
2003-01-16 |
2005-10-19 |
Genentech, Inc. |
Phagenbibliothek von synthetischen antikörpern
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
EP3023498B1
(de)
|
2003-03-06 |
2018-11-28 |
BASF Enzymes LLC |
Amylasen, nukleinsäuren zur codierung davon und verfahren zur herstellung und verwendung davon
|
EP2853593B1
(de)
|
2003-03-07 |
2017-10-04 |
DSM IP Assets B.V. |
Hydrolasen, Nucleinsäuren zur Codierung davon sowie Verfahren zur Herstellung und Verwendung davon
|
EP2341136B1
(de)
|
2003-04-04 |
2016-06-08 |
BASF Enzymes LLC |
Pektatlyasen, Nukleinsäuren, die für diese kodieren und Verfahren zu deren Herstellung und Verwendung
|
US20050250106A1
(en)
*
|
2003-04-24 |
2005-11-10 |
David Epstein |
Gene knock-down by intracellular expression of aptamers
|
US7964714B2
(en)
*
|
2003-05-12 |
2011-06-21 |
Potomac Pharmaceuticals Inc. |
Gene expression suppression agents
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
AU2004254640B2
(en)
|
2003-07-02 |
2010-08-26 |
Bp Corporation North America Inc. |
Glucanases, nucleic acids encoding them and methods for making and using them
|
SI2784084T2
(sl)
|
2003-07-08 |
2024-02-29 |
Novartis Pharma Ag |
Antagonistična protitelesa proti IL-17 A/F heterolognim polipeptidom
|
KR20060069825A
(ko)
*
|
2003-08-01 |
2006-06-22 |
제넨테크, 인크. |
제한된 다양성을 갖는 항체 cdr 폴리펩티드 서열
|
EP1660631B1
(de)
*
|
2003-08-01 |
2013-04-24 |
Life Technologies Corporation |
Zusammensetzungen und verfahren zur aufreinigung kurzer rna-moleküle
|
US7741089B2
(en)
|
2003-08-11 |
2010-06-22 |
Verenium Corporation |
Laccases, nucleic acids encoding them and methods for making and using them
|
JP2005065575A
(ja)
*
|
2003-08-22 |
2005-03-17 |
Japan Science & Technology Agency |
フレームシャッフリングによるタンパク質分子多様性集団の作製
|
CA2537055A1
(en)
*
|
2003-08-22 |
2005-04-21 |
Medimmune, Inc. |
Humanization of antibodies
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
SI2161283T1
(sl)
|
2003-11-17 |
2014-10-30 |
Genentech, Inc. |
Sestavki, ki obsegajo protitelesa proti CD79b, konjugirana na sredstvo, ki inhibira rast, ali na citotoksično sredstvo, in postopki za zdravljenje tumorja hematopoetskega izvora
|
US20050112585A1
(en)
*
|
2003-11-21 |
2005-05-26 |
Dominic Zichi |
Method for adjusting the quantification range of individual analytes in a multiplexed assay
|
EP2221315A1
(de)
|
2003-12-04 |
2010-08-25 |
Xencor, Inc. |
Verfahren zur Erzeugung von Proteinvarianten mit erhöhtem Wirtsstranginhalt und Zusammensetzungen davon
|
WO2005062868A2
(en)
*
|
2003-12-19 |
2005-07-14 |
Osteotech, Inc. |
Tissue-derived mesh for orthopedic regeneration
|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
PT3385384T
(pt)
|
2004-02-12 |
2020-06-30 |
Archemix Llc |
Terapêuticas com aptâmeros úteis no tratamento de desordens relacionadas com o complemento
|
US20060193821A1
(en)
*
|
2004-03-05 |
2006-08-31 |
Diener John L |
Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
|
BRPI0508363A
(pt)
*
|
2004-03-05 |
2007-07-24 |
Archemix Corp |
aptámeros para a famìlia de citocinas de il-12 humana e seus usos como terapia de doença auto-imune
|
US7569223B2
(en)
*
|
2004-03-22 |
2009-08-04 |
The Rockefeller University |
Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
|
WO2005092925A2
(en)
|
2004-03-24 |
2005-10-06 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
US7785903B2
(en)
*
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
US20080214489A1
(en)
*
|
2004-04-19 |
2008-09-04 |
Anthony Dominic Keefe |
Aptamer-mediated intracellular delivery of oligonucleotides
|
WO2005106042A2
(en)
|
2004-04-22 |
2005-11-10 |
Regado Biosciences, Inc. |
Improved modulators of coagulation factors
|
US7579450B2
(en)
|
2004-04-26 |
2009-08-25 |
Archemix Corp. |
Nucleic acid ligands specific to immunoglobulin E and their use as atopic disease therapeutics
|
WO2005106012A2
(en)
|
2004-04-28 |
2005-11-10 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 1 (dpp1)
|
WO2005118647A2
(en)
*
|
2004-05-18 |
2005-12-15 |
Genentech, Inc. |
M13 virus major coat protein variants for c-terminal and bi-terminal display of a heterologous protein
|
CA2570872A1
(en)
|
2004-06-16 |
2006-01-26 |
Diversa Corporation |
Compositions and methods for enzymatic decolorization of chlorophyll
|
KR20070101227A
(ko)
|
2004-09-07 |
2007-10-16 |
아케믹스 코포레이션 |
폰 빌레브란트 인자에 대한 앱타머 및 이의 혈전증치료제로서의 용도
|
CA2578046A1
(en)
*
|
2004-09-07 |
2006-03-16 |
Archemix Corp. |
Aptamer medicinal chemistry
|
US7566701B2
(en)
*
|
2004-09-07 |
2009-07-28 |
Archemix Corp. |
Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
|
GB0422052D0
(en)
|
2004-10-04 |
2004-11-03 |
Dansico As |
Enzymes
|
GB0423139D0
(en)
|
2004-10-18 |
2004-11-17 |
Danisco |
Enzymes
|
US9200079B2
(en)
|
2004-11-12 |
2015-12-01 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
ES2323651T3
(es)
*
|
2005-01-05 |
2009-07-22 |
F-Star Biotechnologische Forschungs- Und Entwicklungsges.M.B.H. |
Dominios sinteticos de inmunoglobulina con propiedades de union elaborados por ingenieria en regiones de la molecula diferentes de las regiones que determinan la complementariedad.
|
PA8660701A1
(es)
|
2005-02-04 |
2006-09-22 |
Pfizer Prod Inc |
Agonistas de pyy y sus usos
|
EP2192132A3
(de)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-il-20-, Anti-il-22- und Anti-il-22ra-Antikörper und Bindungspartner sowie Verwendungsverfahren bei Entzündungen
|
EP1869174B1
(de)
|
2005-03-10 |
2015-02-18 |
BASF Enzymes LLC |
Lyase-enzyme, nukleinsäuren zu deren kodierung und verfahren zu deren herstellung und verwendung
|
CA2597325A1
(en)
|
2005-03-10 |
2006-09-21 |
Genentech, Inc. |
Methods and compositions for modulating vascular integrity
|
CA2861310A1
(en)
|
2005-03-15 |
2006-09-28 |
Bp Corporation North America Inc. |
Cellulases, nucleic acids encoding them and methods for making and using them
|
PA8672101A1
(es)
|
2005-04-29 |
2006-12-07 |
Centocor Inc |
Anticuerpos anti-il-6, composiciones, métodos y usos
|
EP3683230A1
(de)
|
2005-05-12 |
2020-07-22 |
ZymoGenetics, Inc. |
Zusammensetzungen und verfahren zur modulation von immunsystemreaktionen
|
US20060271262A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Mclain Harry P Iii |
Wireless agricultural network
|
US8389469B2
(en)
*
|
2005-06-06 |
2013-03-05 |
The Rockefeller University |
Bacteriophage lysins for Bacillus anthracis
|
DK2452694T3
(en)
|
2005-06-30 |
2019-03-04 |
Janssen Biotech Inc |
Anti-IL-23 antibodies, compositions, methods and applications
|
CN101379085B
(zh)
*
|
2005-06-30 |
2013-03-27 |
Abbvie公司 |
Il-12/p40结合蛋白
|
US7582291B2
(en)
*
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
EP1928506A4
(de)
|
2005-08-19 |
2009-10-21 |
Abbott Lab |
Doppel-variabel-domänen-immunglobulin und seine verwendungen
|
US7612181B2
(en)
*
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP2500357A3
(de)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Immunglobuline mit zweifacher variabler Domäne und ihre Verwendung
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
EP2360248A1
(de)
|
2005-08-24 |
2011-08-24 |
The Rockefeller University |
PLY-GBS-mutante Lysine
|
WO2007035527A2
(en)
|
2005-09-15 |
2007-03-29 |
Duke University |
Non-fouling polymeric surface modification and signal amplification method for biomolecular detection
|
ES2542501T3
(es)
*
|
2005-09-30 |
2015-08-06 |
Abbvie Deutschland Gmbh & Co Kg |
Dominios de unión de proteínas de la familia de proteínas de moléculas de orientación repulsiva (RGM) y fragmentos funcionales de las mismas, así como su uso
|
US8679490B2
(en)
|
2005-11-07 |
2014-03-25 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus VH/VL hypervariable sequences
|
GB2432366B
(en)
*
|
2005-11-19 |
2007-11-21 |
Alligator Bioscience Ab |
A method for in vitro molecular evolution of protein function
|
ES2453941T5
(es)
|
2005-11-30 |
2017-05-31 |
Abbvie Inc. |
Anticuerpos monoclonales contra la proteína beta amiloide y usos de los mismos
|
US8691224B2
(en)
*
|
2005-11-30 |
2014-04-08 |
Abbvie Inc. |
Anti-Aβ globulomer 5F7 antibodies
|
EP1973951A2
(de)
*
|
2005-12-02 |
2008-10-01 |
Genentech, Inc. |
Bindende polypeptide mit eingeschränkten diversitätssequenzen
|
MY163032A
(en)
|
2005-12-29 |
2017-07-31 |
Centocor Inc |
Human anti-il-23 antibodies, compositions, methods and uses
|
US20090324574A1
(en)
|
2006-02-02 |
2009-12-31 |
Verenium Corporation |
Esterases and Related Nucleic Acids and Methods
|
WO2007092313A2
(en)
*
|
2006-02-03 |
2007-08-16 |
Indiana University Research And Technology Corporation |
Construction of open reading frame libraries and protein structures
|
MY160770A
(en)
|
2006-02-10 |
2017-03-15 |
Verenium Corp |
Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
|
BRPI0707784B1
(pt)
|
2006-02-14 |
2018-05-22 |
Verenium Corporation |
Ácido nucléico isolado, sintético ou recombinante, cassete de expressão, vetor ou veículo de clonagem, célula hospedeira isolada transformada, e método para produção de um polipeptídeo recombinante
|
US8043837B2
(en)
|
2006-03-07 |
2011-10-25 |
Cargill, Incorporated |
Aldolases, nucleic acids encoding them and methods for making and using them
|
EP2388316A3
(de)
|
2006-03-07 |
2012-03-14 |
Verenium Corporation |
Adolasen, Nukleinsäuren, die diese codieren, und Verfahren zu deren Herstellung und Verwendung
|
RU2477137C2
(ru)
*
|
2006-03-08 |
2013-03-10 |
АРКЕМИКС Эл Эл Си |
Связывающие комплемент аптамеры и средства против с5, пригодные для лечения глазных нарушений
|
WO2007126455A2
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
EP2016101A2
(de)
*
|
2006-05-09 |
2009-01-21 |
Genentech, Inc. |
Bindung von polypeptiden mit optimierten gerüsten
|
AT503889B1
(de)
*
|
2006-07-05 |
2011-12-15 |
Star Biotechnologische Forschungs Und Entwicklungsges M B H F |
Multivalente immunglobuline
|
AT503902B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von immunglobulinen
|
AT503861B1
(de)
|
2006-07-05 |
2008-06-15 |
F Star Biotech Forsch & Entw |
Verfahren zur manipulation von t-zell-rezeptoren
|
WO2008012629A2
(en)
|
2006-07-24 |
2008-01-31 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
US20110117067A1
(en)
|
2006-08-04 |
2011-05-19 |
Verenium Corporation |
Glucanases, Nucleic Acids Encoding Them and Methods for Making and Using Them
|
US8586006B2
(en)
|
2006-08-09 |
2013-11-19 |
Institute For Systems Biology |
Organ-specific proteins and methods of their use
|
CN101512008B
(zh)
|
2006-09-08 |
2015-04-01 |
艾伯维巴哈马有限公司 |
白介素-13结合蛋白
|
EP2083017A4
(de)
|
2006-09-14 |
2011-01-12 |
Med & Biological Lab Co Ltd |
Antikörper mit verbesserter adcc-wirkung und verfahren zu dessen herstellung
|
DK2617823T3
(da)
|
2006-09-21 |
2015-10-05 |
Basf Enzymes Llc |
Phytaser, nukleinsyrer, der koder for disse, og fremgangsmåde til fremstilling og anvendelse heraf
|
ES2451266T3
(es)
|
2006-09-21 |
2014-03-26 |
Dsm Ip Assets B.V. |
Fosfolipasas, ácidos nucleicos que las codifican, y métodos para obtenerlas y usarlas
|
US9382327B2
(en)
*
|
2006-10-10 |
2016-07-05 |
Vaccinex, Inc. |
Anti-CD20 antibodies and methods of use
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
EP2479266B1
(de)
|
2006-12-21 |
2016-03-09 |
BASF Enzymes LLC |
Amylasen und Glucoamylasen, dafür kodierende Nukleinsäuren sowie Verfahren zu ihrer Herstellung und Verwendung
|
US7964356B2
(en)
|
2007-01-16 |
2011-06-21 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7855054B2
(en)
|
2007-01-16 |
2010-12-21 |
Somalogic, Inc. |
Multiplexed analyses of test samples
|
US8975026B2
(en)
|
2007-01-16 |
2015-03-10 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US7947447B2
(en)
|
2007-01-16 |
2011-05-24 |
Somalogic, Inc. |
Method for generating aptamers with improved off-rates
|
US20110136099A1
(en)
|
2007-01-16 |
2011-06-09 |
Somalogic, Inc. |
Multiplexed Analyses of Test Samples
|
CA2675366A1
(en)
*
|
2007-01-18 |
2008-07-24 |
University Of Southern California |
Gene polymorphisms predictive for dual tki therapy
|
CA2674721C
(en)
|
2007-01-30 |
2018-04-03 |
Verenium Corporation |
Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
|
US8143046B2
(en)
|
2007-02-07 |
2012-03-27 |
Danisco Us Inc., Genencor Division |
Variant Buttiauxella sp. phytases having altered properties
|
AU2008218925A1
(en)
*
|
2007-02-20 |
2008-08-28 |
Anaptysbio, Inc. |
Somatic hypermutation systems
|
US7875431B2
(en)
|
2007-02-22 |
2011-01-25 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
EP2124952A2
(de)
*
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Verfahren zur behandlung von amyloidosen
|
US20090232801A1
(en)
*
|
2007-05-30 |
2009-09-17 |
Abbot Laboratories |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
|
PE20090329A1
(es)
*
|
2007-05-30 |
2009-03-27 |
Abbott Lab |
Anticuerpos humanizados contra el globulomero ab(20-42) y sus usos
|
US20090203766A1
(en)
*
|
2007-06-01 |
2009-08-13 |
Archemix Corp. |
vWF aptamer formulations and methods for use
|
ES2975748T3
(es)
|
2007-06-26 |
2024-07-12 |
F Star Therapeutics Ltd |
Presentación de agentes de unión
|
EP4056711A1
(de)
|
2007-07-17 |
2022-09-14 |
SomaLogic Operating Co., Inc. |
Verfahren zur herstellung von aptameren mit verringerten ausfallraten
|
EP2033971A1
(de)
*
|
2007-09-06 |
2009-03-11 |
Abbott GmbH & Co. KG |
Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
US8691730B2
(en)
|
2007-09-14 |
2014-04-08 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
CA2697583C
(en)
|
2007-09-28 |
2016-04-12 |
Portola Pharmaceuticals, Inc. |
Antidotes for factor xa inhibitors and methods of using the same
|
NZ584967A
(en)
|
2007-10-03 |
2012-08-31 |
Verenium Corp |
Xylanases, nucleic acids encoding them and methods for making and using them
|
US8957031B2
(en)
*
|
2007-10-23 |
2015-02-17 |
Regents Of The University Of Colorado, A Body Corporate |
Competitive inhibitors of invariant chain expression and/or ectopic clip binding
|
WO2009055656A2
(en)
|
2007-10-26 |
2009-04-30 |
Centocor, Inc. |
Vectors, host cells, and methods of production and uses
|
US8906700B2
(en)
|
2007-11-06 |
2014-12-09 |
Ambergen, Inc. |
Methods and compositions for phototransfer
|
US9102711B2
(en)
*
|
2007-12-31 |
2015-08-11 |
Xoma Technology Ltd. |
Methods and materials for targeted mutagenesis
|
WO2009088753A1
(en)
|
2008-01-03 |
2009-07-16 |
Verenium Corporation |
Isomerases, nucleic acids encoding them and methods for making and using them
|
EP2238242B9
(de)
|
2008-01-03 |
2015-06-10 |
BASF Enzymes LLC |
Transferasen und oxidoreduktasen, dafür kodierende nukleinsäuren sowie verfahren zu ihrer herstellung und verwendung
|
US7682809B2
(en)
|
2008-01-11 |
2010-03-23 |
Agilent Technologies, Inc. |
Direct ATP release sequencing
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
US9873957B2
(en)
|
2008-03-13 |
2018-01-23 |
Dyax Corp. |
Libraries of genetic packages comprising novel HC CDR3 designs
|
DK2281078T3
(en)
*
|
2008-04-24 |
2015-02-02 |
Dyax Corp |
LIBRARIES OF RE-PACKAGES INCLUDING UNKNOWN HC-CDR1, -CDR2 AND -CDR3 AND UNKNOWN LC-CDR1, -CDR2 AND-CDR3 DESIGNS
|
SG190572A1
(en)
|
2008-04-29 |
2013-06-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
WO2009133462A2
(en)
|
2008-04-30 |
2009-11-05 |
Danisco A/S |
Proteins
|
EP2113255A1
(de)
|
2008-05-02 |
2009-11-04 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Zytotoxisches Immunglobulin
|
CN104558178A
(zh)
|
2008-05-09 |
2015-04-29 |
Abbvie公司 |
针对渐进性糖化终极产物受体(rage)的抗体及其用途
|
UY31861A
(es)
*
|
2008-06-03 |
2010-01-05 |
Abbott Lab |
Inmunoglobulina con dominio variable dual y usos de la misma
|
SG191639A1
(en)
*
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
CA2728308A1
(en)
|
2008-06-20 |
2009-12-23 |
Wyeth Llc |
Compositions and methods of use of orf1358 from beta-hemolytic streptococcal strains
|
US8575314B2
(en)
*
|
2008-06-20 |
2013-11-05 |
National University Corporation Okayama University |
Antibody against oxidized LDL/β2GPI complex and use of the same
|
TW201014602A
(en)
|
2008-07-08 |
2010-04-16 |
Abbott Lab |
Prostaglandin E2 binding proteins and uses thereof
|
BRPI0915448A2
(pt)
*
|
2008-07-08 |
2015-11-10 |
Abbott Lab |
imunoglobulinas de domínio variável duplo para prostaglandina e2 e usos das mesmas
|
US8703416B2
(en)
|
2008-07-17 |
2014-04-22 |
Somalogic, Inc. |
Method for purification and identification of sperm cells
|
AU2009274568A1
(en)
*
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Proteins for use in diagnosing and treating infection and disease
|
US20100166782A1
(en)
*
|
2008-07-25 |
2010-07-01 |
Martha Karen Newell |
Clip inhibitors and methods of modulating immune function
|
US9182406B2
(en)
*
|
2008-08-04 |
2015-11-10 |
Biodesy, Inc. |
Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
|
CA2733642A1
(en)
|
2008-08-14 |
2010-02-18 |
Cephalon Australia Pty Ltd |
Anti-il-12/il-23 antibodies
|
US8153391B2
(en)
|
2008-08-29 |
2012-04-10 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8357503B2
(en)
|
2008-08-29 |
2013-01-22 |
Bunge Oils, Inc. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
US8198062B2
(en)
|
2008-08-29 |
2012-06-12 |
Dsm Ip Assets B.V. |
Hydrolases, nucleic acids encoding them and methods for making and using them
|
EP2360172B1
(de)
|
2008-10-20 |
2017-10-18 |
Gwangju Institute of Science and Technology |
Bipodaler peptidbinder
|
SG171812A1
(en)
*
|
2008-12-04 |
2011-07-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
US8492133B2
(en)
|
2009-01-20 |
2013-07-23 |
Ramot At Tel Aviv University, Ltd. |
MIR-21 promoter driven targeted cancer therapy
|
JP2012516153A
(ja)
*
|
2009-01-29 |
2012-07-19 |
アボット・ラボラトリーズ |
Il−1結合タンパク質
|
US20110165063A1
(en)
*
|
2009-01-29 |
2011-07-07 |
Abbott Laboratories |
Il-1 binding proteins
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
KR101579771B1
(ko)
|
2009-03-05 |
2015-12-28 |
애브비 인코포레이티드 |
Il-17 결합 단백질
|
EP2414517B1
(de)
|
2009-03-30 |
2016-09-21 |
Portola Pharmaceuticals, Inc. |
Gegenmittel für faktor-xa-hemmer und verwendungsverfahren dafür
|
GB0908770D0
(en)
|
2009-04-24 |
2009-07-01 |
Danisco |
Method
|
US9695403B2
(en)
|
2009-05-21 |
2017-07-04 |
Syngenta Participations Ag |
Phytases, nucleic acids encoding them and methods for making and using them
|
JP6163304B2
(ja)
|
2009-07-15 |
2017-07-12 |
ポートラ ファーマシューティカルズ, インコーポレイテッド |
第Xa因子インヒビターの解毒剤の単位用量処方物およびその使用方法
|
UY32808A
(es)
*
|
2009-07-29 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas como dominio variable dual y usos de las mismas
|
MX2012002605A
(es)
|
2009-08-29 |
2012-04-02 |
Abbott Lab |
Proteinas terapeutico de union a dll4.
|
MX2012002651A
(es)
|
2009-09-01 |
2012-05-22 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
AU2010291902A1
(en)
*
|
2009-09-14 |
2012-04-05 |
Dyax Corp. |
Libraries of genetic packages comprising novel HC CDR3 designs
|
EP3187877A1
(de)
|
2009-09-25 |
2017-07-05 |
XOMA Technology Ltd. |
Screening-verfahren
|
US8926976B2
(en)
|
2009-09-25 |
2015-01-06 |
Xoma Technology Ltd. |
Modulators
|
WO2011047262A2
(en)
|
2009-10-15 |
2011-04-21 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
UA111708C2
(uk)
|
2009-10-16 |
2016-06-10 |
Бандж Ойлз, Інк. |
Спосіб рафінування олії
|
UA109884C2
(uk)
|
2009-10-16 |
2015-10-26 |
|
Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
|
WO2011050194A1
(en)
|
2009-10-22 |
2011-04-28 |
Genentech, Inc. |
Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
TW201121568A
(en)
*
|
2009-10-31 |
2011-07-01 |
Abbott Lab |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
PE20121584A1
(es)
|
2009-11-30 |
2012-11-29 |
Genentech Inc |
Composiciones y metodos para el diagnostico y el tratamiento de tumores
|
ES2562832T3
(es)
*
|
2009-12-08 |
2016-03-08 |
Abbvie Deutschland Gmbh & Co Kg |
Anticuerpos monoclonales contra la proteína RGM para su uso en el tratamiento de la degeneración de la capa de fibra nerviosa de la retina
|
CN105001334A
(zh)
|
2010-02-10 |
2015-10-28 |
伊缪诺金公司 |
Cd20抗体及其用途
|
PL2536748T3
(pl)
|
2010-02-18 |
2015-01-30 |
Genentech Inc |
Antagoniści neureguliny i ich zastosowanie w leczeniu nowotworu
|
EP2538981B1
(de)
|
2010-02-23 |
2017-12-20 |
F. Hoffmann-La Roche AG |
Zusammensetzungen und methoden zur diagnose und behandlung von tumoren
|
DK2538976T3
(en)
|
2010-02-24 |
2017-02-27 |
Immunogen Inc |
IMMUNCONJUGATES AGAINST FOLATRECEPTOR-1 AND APPLICATIONS THEREOF
|
PE20130580A1
(es)
|
2010-03-02 |
2013-06-02 |
Abbvie Inc |
Proteinas terapeuticas de union a dll4
|
WO2011109642A1
(en)
|
2010-03-03 |
2011-09-09 |
Somalogic, Inc. |
Aptamers to 4-1bb and their use in treating diseases and disorders
|
CA2795043C
(en)
|
2010-03-30 |
2019-04-23 |
Janssen Biotech, Inc. |
Humanized il-25 antibodies
|
CA2797188C
(en)
|
2010-04-12 |
2020-03-31 |
Somalogic, Inc. |
5-position modified pyrimidines and their use
|
US8987419B2
(en)
|
2010-04-15 |
2015-03-24 |
AbbVie Deutschland GmbH & Co. KG |
Amyloid-beta binding proteins
|
WO2011139985A1
(en)
|
2010-05-03 |
2011-11-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
EP2571532B1
(de)
|
2010-05-14 |
2017-05-03 |
Abbvie Inc. |
Il-1-bindende proteine
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
GB201011513D0
(en)
|
2010-07-08 |
2010-08-25 |
Danisco |
Method
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
DK3336225T3
(da)
|
2010-07-16 |
2020-03-30 |
Adimab Llc |
Antistofbiblioteker
|
PE20131412A1
(es)
|
2010-08-03 |
2014-01-19 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
CA2808187A1
(en)
|
2010-08-14 |
2012-02-23 |
Abbvie Inc. |
Amyloid-beta binding proteins
|
ES2665954T3
(es)
|
2010-08-19 |
2018-04-30 |
Zoetis Belgium S.A. |
Anticuerpos anti-NGF y su uso
|
TW201211252A
(en)
|
2010-08-26 |
2012-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
AR083354A1
(es)
|
2010-10-06 |
2013-02-21 |
Bp Corp North America Inc |
Polipeptidos variantes cbh i (celobiohidrolasas i) con reducida inhibicion de producto
|
CA2821976A1
(en)
|
2010-12-21 |
2012-09-13 |
Abbvie Inc. |
Il-1 -alpha and -beta bispecific dual variable domain immunoglobulins and their use
|
US20120275996A1
(en)
|
2010-12-21 |
2012-11-01 |
Abbott Laboratories |
IL-1 Binding Proteins
|
CN103620032B
(zh)
|
2010-12-31 |
2016-02-24 |
生物蛋白有限公司 |
抗体的快速人源化
|
AU2012230899A1
(en)
|
2011-03-21 |
2013-10-10 |
Biodesy, Llc |
Classification of kinase inhibitors using nonlinear optical techniques
|
CN107189997A
(zh)
|
2011-04-21 |
2017-09-22 |
洛克菲勒大学 |
用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
|
EP2734236A4
(de)
|
2011-07-13 |
2015-04-15 |
Abbvie Inc |
Verfahren und zusammensetzungen zur behandlung von asthma mit anti-il-13-antikörpern
|
WO2013016449A2
(en)
|
2011-07-26 |
2013-01-31 |
Indicator Systems International, Inc. |
Assays for the detection of microbes
|
JP2014533927A
(ja)
|
2011-09-15 |
2014-12-18 |
ジェネンテック, インコーポレイテッド |
分化を促進する方法
|
CN104114695B
(zh)
|
2011-10-05 |
2018-04-17 |
洛克菲勒大学 |
二聚噬菌体溶素
|
JP6254087B2
(ja)
|
2011-10-15 |
2017-12-27 |
ジェネンテック, インコーポレイテッド |
癌を治療するためのscd1アンタゴニスト
|
RU2014120981A
(ru)
|
2011-10-24 |
2015-12-10 |
Эббви Инк. |
Иммунные связывающие агенты против склеростина
|
CN104093743B
(zh)
|
2011-11-23 |
2018-04-24 |
医学免疫有限责任公司 |
特异于her3的结合分子及其用途
|
JP6336397B2
(ja)
|
2011-12-14 |
2018-06-06 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
鉄関連障害を診断および治療するための組成物および方法
|
WO2013090635A2
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
AR089529A1
(es)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17
|
CA2862424A1
(en)
|
2012-01-18 |
2013-07-25 |
Genentech, Inc. |
Methods of using fgf19 modulators
|
MX359854B
(es)
|
2012-01-20 |
2018-10-12 |
Genzyme Corp |
Anticuerpos anti-cxcr3.
|
BR112014018592B1
(pt)
|
2012-01-27 |
2022-03-15 |
Abbvie Inc. |
Anticorpo monoclonal isolado que se liga à molécula de orientação repulsiva a (rgma)
|
US20130209473A1
(en)
|
2012-02-11 |
2013-08-15 |
Genentech, Inc. |
R-spondin translocations and methods using the same
|
JP6181089B2
(ja)
|
2012-03-08 |
2017-08-16 |
ハロザイム インコーポレイテッド |
条件依存活性抗上皮細胞増殖因子受容体抗体およびその使用方法
|
WO2013136193A2
(en)
|
2012-03-16 |
2013-09-19 |
University Health Network |
Methods and compositions for modulating toso activity
|
US9139863B2
(en)
|
2012-03-16 |
2015-09-22 |
Genentech, Inc. |
Engineered conformationally-stabilized proteins
|
KR20140142293A
(ko)
|
2012-03-16 |
2014-12-11 |
제넨테크, 인크. |
조작된 입체형태적으로-안정화된 단백질
|
MX2014010953A
(es)
|
2012-03-16 |
2014-10-13 |
Hoffmann La Roche |
Metodos para tratamiento de melanoma con inhibidores pak1.
|
US9592289B2
(en)
|
2012-03-26 |
2017-03-14 |
Sanofi |
Stable IgG4 based binding agent formulations
|
EP2841951B1
(de)
|
2012-04-25 |
2019-12-11 |
Biodesy, Inc. |
Verfahren zum nachweis von allosterischen proteinmodulatoren
|
WO2013170191A1
(en)
|
2012-05-11 |
2013-11-14 |
Genentech, Inc. |
Methods of using antagonists of nad biosynthesis from nicotinamide
|
MX369626B
(es)
|
2012-05-24 |
2019-11-13 |
Mountgate Group Ltd |
Composiciones y metodos relacionados con la prevencion y el tratamiento de infecciones por rabia.
|
CN104364264B
(zh)
|
2012-06-06 |
2018-07-24 |
硕腾服务有限责任公司 |
犬源化抗ngf抗体和其方法
|
UY34905A
(es)
|
2012-07-12 |
2014-01-31 |
Abbvie Inc |
Proteínas de unión a il-1
|
CN104755498B
(zh)
|
2012-08-31 |
2019-06-18 |
伊缪诺金公司 |
用于检测叶酸受体1的诊断测定和试剂盒
|
TW202037609A
(zh)
|
2012-11-01 |
2020-10-16 |
美商艾伯維有限公司 |
抗-vegf/dll4雙重可變區域免疫球蛋白及其用途
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
CA2900097A1
(en)
|
2013-02-22 |
2014-08-28 |
F. Hoffmann-La Roche Ag |
Methods of treating cancer and preventing drug resistance
|
EP2964260A2
(de)
|
2013-03-06 |
2016-01-13 |
F. Hoffmann-La Roche AG |
Verfahren zur behandlung und prävention einer antikrebsmittelresistenz
|
GB201308828D0
(en)
|
2013-03-12 |
2013-07-03 |
Verenium Corp |
Phytase
|
JP2016516046A
(ja)
|
2013-03-14 |
2016-06-02 |
ジェネンテック, インコーポレイテッド |
がんの治療方法及びがん薬物耐性を阻止する方法
|
WO2014143343A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbott Laboratories |
Hcv core lipid binding domain monoclonal antibodies
|
GB201308843D0
(en)
|
2013-03-14 |
2013-07-03 |
Verenium Corp |
Phytase formulation
|
BR112015023355A8
(pt)
|
2013-03-14 |
2018-01-30 |
Abbott Lab |
antígenos recombinantes ns3 de hcv e mutantes dos mesmos para detecção de anticorpos aprimorada.
|
WO2014158272A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbott Laboratories |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
WO2014144280A2
(en)
|
2013-03-15 |
2014-09-18 |
Abbvie Inc. |
DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
|
WO2014150914A2
(en)
|
2013-03-15 |
2014-09-25 |
Pioneer Hi-Bred International, Inc. |
Phi-4 polypeptides and methods for their use
|
BR112015023203A8
(pt)
|
2013-03-15 |
2018-01-23 |
Constellation Pharmaceuticals Inc |
métodos para tratamento de câncer, método para aumentar a eficiência de um tratamento de câncer, método para retardar e/ou prevenir o desenvolvimento de câncer, método para tratar um indivíduo com câncer, método para aumentar a sensibilidade para um agente de terapia para câncer, método para estender um período de sensibilidade e método para estender a duração da resposta para uma terapia para câncer.
|
KR20230070054A
(ko)
|
2013-03-15 |
2023-05-19 |
제넨테크, 인크. |
Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
CA2914566A1
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
KR20160033711A
(ko)
|
2013-07-25 |
2016-03-28 |
바스프 엔자임스 엘엘씨 |
피타아제
|
MX359026B
(es)
|
2013-08-16 |
2018-09-12 |
Pioneer Hi Bred Int |
Proteinas insecticidas y metodos de uso.
|
EP3925980A1
(de)
|
2013-08-30 |
2021-12-22 |
ImmunoGen, Inc. |
Antikörper und tests zum nachweis von folatrezeptor 1
|
MX2016003256A
(es)
|
2013-09-12 |
2016-06-07 |
Halozyme Inc |
Anticuerpos modificados del receptor de factor de crecimiento anti-epidermico y metodos de uso de los mismos.
|
MX359027B
(es)
|
2013-09-13 |
2018-09-12 |
Pioneer Hi Bred Int |
Proteinas insecticidas y metodos para su uso.
|
CN114163529A
(zh)
|
2013-12-24 |
2022-03-11 |
杨森制药公司 |
抗vista抗体及片段
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
UA120608C2
(uk)
|
2014-02-07 |
2020-01-10 |
Піонір Хай-Бред Інтернешнл, Інк. |
Очищений поліпептид ptip-83 та спосіб його застосування
|
CA2938979C
(en)
|
2014-02-07 |
2024-02-20 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
EP3113798B1
(de)
|
2014-03-07 |
2019-06-05 |
University Health Network |
Verfahren und zusammensetzungen zur modifikation der immunantwort
|
CA2948275C
(en)
|
2014-04-08 |
2023-10-17 |
Boston Pharmaceuticals Inc. |
Binding molecules specific for il-21 and uses thereof
|
BR112016022910A2
(pt)
|
2014-04-11 |
2017-10-17 |
Medimmune Llc |
anticorpos contra her2 biespecíficos
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
CA3225091A1
(en)
|
2014-05-05 |
2015-11-12 |
Regeneron Pharmaceuticals, Inc. |
Humanized c5 and c3 animals
|
WO2015179835A2
(en)
|
2014-05-23 |
2015-11-26 |
Genentech, Inc. |
Mit biomarkers and methods using the same
|
EP3154589A1
(de)
|
2014-06-13 |
2017-04-19 |
Genentech, Inc. |
Verfahren zur behandlung und prävention der antikrebsmittelresistenz
|
EP3157945A4
(de)
|
2014-06-20 |
2017-11-22 |
F. Hoffmann-La Roche AG |
Chagasinbasierten gerüstzusammensetzungen, verfahren und verwendungen
|
BR112017007932A2
(pt)
|
2014-10-16 |
2018-01-23 |
Du Pont |
proteínas inseticidas e métodos para uso das mesmas
|
DK3209773T3
(da)
|
2014-10-24 |
2020-06-15 |
Dupont Nutrition Biosci Aps |
Prolintolerante tripeptidylpeptidaser og anvendelser deraf
|
BR112017007949A2
(pt)
|
2014-10-24 |
2018-01-23 |
Danisco Us Inc |
método para produção de álcool pelo uso de uma tripeptidil-peptidase
|
RS62003B1
(sr)
|
2014-11-10 |
2021-07-30 |
Medimmune Ltd |
Vezujući molekuli specifični za cd73 i njihove upotrebe
|
EP3789403A1
(de)
|
2014-11-11 |
2021-03-10 |
MedImmune Limited |
Therapeutische kombinationen mit anti-cd73-antikörpern und a2a-rezeptorinhibitoren sowie verwendungen davon
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
WO2016106286A1
(en)
|
2014-12-23 |
2016-06-30 |
Biodesy, Inc. |
Attachment of proteins to interfaces for use in nonlinear optical detection
|
AU2016206682B2
(en)
|
2015-01-14 |
2021-11-11 |
The Brigham And Women's Hospital, Inc. |
Treatment of cancer with anti-LAP monoclonal antibodies
|
EA038923B1
(ru)
|
2015-03-11 |
2021-11-10 |
Пайонир Хай-Бред Интернэшнл, Инк. |
Инсектицидная днк-конструкция и способы её применения
|
EP3286227A2
(de)
|
2015-04-24 |
2018-02-28 |
F. Hoffmann-La Roche AG |
Multispezifische antigenbindende proteine
|
CA2985198A1
(en)
|
2015-05-19 |
2016-11-24 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
WO2016196314A1
(en)
|
2015-05-29 |
2016-12-08 |
Abbvie Inc. |
Anti-cd40 antibodies and uses thereof
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
BR112017027870A2
(pt)
|
2015-06-24 |
2018-08-28 |
Janssen Pharmaceutica Nv |
anticorpos e fragmentos anti-vista
|
WO2016210395A1
(en)
|
2015-06-26 |
2016-12-29 |
Dupont Nutrition Biosciences Aps |
Aminopeptidases for protein hydrlyzates
|
US10077313B2
(en)
|
2015-06-29 |
2018-09-18 |
Immunogen, Inc. |
Anti-CD123 antibodies and conjugates and derivatives thereof
|
WO2017011275A1
(en)
|
2015-07-10 |
2017-01-19 |
Nersissian Aram M |
Factor viii protein compositions and methods of treating hemophilia a
|
EP3328429A4
(de)
|
2015-07-31 |
2019-03-20 |
The Research Institute at Nationwide Children's Hospital |
Peptide und antikörper zur beseitigung von biofilmen
|
UA124495C2
(uk)
|
2015-08-06 |
2021-09-29 |
Піонір Хай-Бред Інтернешнл, Інк. |
Інсектицидний білок рослинного походження та спосіб його застосування
|
WO2017066719A2
(en)
|
2015-10-14 |
2017-04-20 |
Research Institute At Nationwide Children's Hospital |
Hu specific interfering agents
|
SG11201803068YA
(en)
|
2015-11-10 |
2018-05-30 |
Medimmune Llc |
Binding molecules specific for asct2 and uses thereof
|
CN108575091A
(zh)
|
2015-12-18 |
2018-09-25 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
US11135221B2
(en)
|
2015-12-23 |
2021-10-05 |
Moonshot Pharma Llc |
Methods for inducing an immune response
|
CA3014013A1
(en)
|
2016-02-12 |
2017-08-17 |
Janssen Pharmaceutica Nv |
Anti-vista (b7h5) antibodies
|
CA3013383A1
(en)
|
2016-02-25 |
2017-08-31 |
Dupont Nutrition Biosciences Aps |
Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
|
US10307455B2
(en)
|
2016-03-10 |
2019-06-04 |
Acceleron Pharma Inc. |
Activin type 2 receptor antibodies
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
US10765724B2
(en)
|
2016-03-29 |
2020-09-08 |
Janssen Biotech, Inc. |
Method of treating psoriasis with increased interval dosing of anti-IL12/23 antibody
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
US11390669B2
(en)
|
2016-04-27 |
2022-07-19 |
Abbvie, Inc. |
Methods of treatment of diseases in which IL-13 activity is detrimental using anti-IL-13 antibodies
|
US11008585B2
(en)
|
2016-05-04 |
2021-05-18 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
EP3464318B1
(de)
|
2016-06-02 |
2021-04-21 |
AbbVie Inc. |
Glucocorticoid-rezeptoragonist und immunkonjugate davon
|
CN109641962A
(zh)
|
2016-06-08 |
2019-04-16 |
艾伯维公司 |
抗b7-h3抗体和抗体药物偶联物
|
EP3468993A1
(de)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-b7-h3-antikörper und antikörperarzneimittelkonjugate
|
TW202304996A
(zh)
|
2016-06-08 |
2023-02-01 |
美商艾伯維有限公司 |
抗-b7-h3抗體及抗體藥物結合物
|
GB201610198D0
(en)
|
2016-06-10 |
2016-07-27 |
Ucb Biopharma Sprl |
Anti-ige antibodies
|
US20190330641A1
(en)
|
2016-06-17 |
2019-10-31 |
National Hellenic Research Foundation |
Systems for recombinant protein production
|
MX2018015906A
(es)
|
2016-07-01 |
2019-04-04 |
Pioneer Hi Bred Int |
Proteinas insecticidas de plantas y metodos para sus usos.
|
WO2018049275A1
(en)
|
2016-09-09 |
2018-03-15 |
Genentech, Inc. |
Selective peptide inhibitors of frizzled
|
MX2019003703A
(es)
|
2016-09-30 |
2020-08-13 |
Janssen Biotech Inc |
Método seguro y eficaz para tratar la psoriasis con el anticuerpo específico anti-il23.
|
US20180106800A1
(en)
|
2016-10-03 |
2018-04-19 |
Abbott Laboratories |
Methods of assessing uch-l1 status in patient samples
|
WO2018084936A1
(en)
|
2016-11-01 |
2018-05-11 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
AU2017362222A1
(en)
|
2016-11-16 |
2019-05-30 |
Janssen Biotech, Inc. |
Method of treating psoriasis with anti-IL-23 specific antibody
|
WO2018098363A2
(en)
|
2016-11-23 |
2018-05-31 |
Bioverativ Therapeutics Inc. |
Bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
US10899842B2
(en)
|
2016-11-23 |
2021-01-26 |
Immunoah Therapeutics, Inc. |
4-1BB binding proteins and uses thereof
|
US11174295B2
(en)
|
2016-12-14 |
2021-11-16 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
MX2019007491A
(es)
|
2016-12-22 |
2019-09-06 |
Pioneer Hi Bred Int |
Proteinas insecticidas y metodos para su uso.
|
WO2018129078A1
(en)
|
2017-01-04 |
2018-07-12 |
Research Institute At Nationwide Children's Hospital |
Dnabii vaccines and antibodies with enhanced activity
|
WO2018129092A1
(en)
|
2017-01-04 |
2018-07-12 |
Research Institute At Nationwide Children's Hospital |
Antibody fragments for the treatment of biofilm-related disorders
|
WO2018129029A1
(en)
|
2017-01-04 |
2018-07-12 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
EP3565845A4
(de)
|
2017-01-06 |
2020-10-07 |
Biosion, Inc. |
Erbb2-antikörper und deren verwendungen
|
MX2019008989A
(es)
|
2017-01-30 |
2019-10-09 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la artritis psoriasica activa.
|
KR20240038148A
(ko)
|
2017-02-07 |
2024-03-22 |
얀센 바이오테크 인코포레이티드 |
활성 강직성 척추염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
|
CA3052794A1
(en)
|
2017-02-08 |
2018-08-16 |
Pioneer Hi-Bred International, Inc. |
Insecticidal combinations of plant derived insecticidal proteins and methods for their use
|
WO2018152496A1
(en)
|
2017-02-17 |
2018-08-23 |
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services |
Compositions and methods for the diagnosis and treatment of zika virus infection
|
IL268748B1
(en)
|
2017-02-27 |
2024-09-01 |
Regeneron Pharma |
A human model of kidney and liver disorders
|
EP3595445B1
(de)
|
2017-03-15 |
2024-09-04 |
The Research Institute at Nationwide Children's Hospital |
Zusammensetzung und verfahren zur brechung bakterieller biofilme ohne begleitentzündung
|
CA3052513A1
(en)
|
2017-03-23 |
2018-09-27 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
|
WO2018191531A1
(en)
|
2017-04-15 |
2018-10-18 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
KR20190141686A
(ko)
|
2017-04-21 |
2019-12-24 |
제넨테크, 인크. |
질환 치료를 위한 klk5 길항제의 용도
|
US11236151B2
(en)
|
2017-04-25 |
2022-02-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies and methods for the diagnosis and treatment of Epstein Barr virus infection
|
CN110603449A
(zh)
|
2017-04-28 |
2019-12-20 |
雅培实验室 |
用同一人受试者的至少两种样品的早期生物标记物帮助超急性诊断确定创伤性脑损伤的方法
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
CA3063200A1
(en)
|
2017-05-11 |
2018-11-15 |
Pioneer Hi-Bred International, Inc. |
Insecticidal proteins and methods for their use
|
CA3078725A1
(en)
|
2017-05-25 |
2018-11-29 |
Abbott Laboratories |
Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
|
EP3631466A1
(de)
|
2017-05-30 |
2020-04-08 |
Abbott Laboratories |
Verfahren zur hilfe bei der diagnose und evaluierung einer leichten traumatischen hirnläsion bei einer person unter verwendung von herztroponin i und frühbiomarkern
|
JP2020525434A
(ja)
|
2017-06-22 |
2020-08-27 |
ムーンショット ファーマ エルエルシー |
アンレキサノクス及び免疫調節剤を含む組成物で癌を治療する方法
|
WO2019010131A1
(en)
|
2017-07-03 |
2019-01-10 |
Abbott Laboratories |
IMPROVED METHODS FOR MEASURING CARBOXY TERMINATION HYDROLASE LEVELS OF UBIQUITIN L1 IN BLOOD
|
EP3655430A1
(de)
|
2017-07-19 |
2020-05-27 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Antikörper und verfahren zur diagnose und behandlung von hepatitis-b-virusinfektionen
|
CN110945023B
(zh)
|
2017-07-31 |
2023-08-18 |
豪夫迈·罗氏有限公司 |
基于三维结构的人源化方法
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
CA3078460A1
(en)
|
2017-10-04 |
2019-04-11 |
Opko Pharmaceuticals, Llc |
Articles and methods directed to personalized therapy of cancer
|
EP3694552A1
(de)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap-antikörper und verwendungen davon
|
JP2021502125A
(ja)
|
2017-11-09 |
2021-01-28 |
ピンテオン セラピューティクス インコーポレイテッド |
ヒト化コンホメーション特異的リン酸化タウ抗体の作製および使用のための方法および組成物
|
JP7344801B2
(ja)
|
2017-12-09 |
2023-09-14 |
アボット・ラボラトリーズ |
グリア原線維性酸性タンパク質(gfap)及び/又はユビキチンカルボキシ末端ヒドロラーゼl1(uch-l1)を使用する、整形外科損傷を負っており、軽度外傷性脳損傷(tbi)などの頭部への損傷を負ったか又は負った可能性がある対象についての診断及び査定の一助となるための方法
|
EP3721234A1
(de)
|
2017-12-09 |
2020-10-14 |
Abbott Laboratories |
Verfahren zur unterstützung bei der diagnose und bewertung einer traumatischen hirnverletzung beim menschen mit einer kombination aus gfap und uch-l1
|
US20190211098A1
(en)
|
2017-12-22 |
2019-07-11 |
Genentech, Inc. |
Use of pilra binding agents for treatment of a disease
|
WO2019133717A1
(en)
|
2017-12-29 |
2019-07-04 |
Abbott Laboratories |
Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
KR20200135331A
(ko)
|
2018-02-14 |
2020-12-02 |
비엘라 바이오, 인크. |
고양이 맥도너 육종(fms)-유사 티로신 키나제 3 수용체 리간드(flt3l)에 대한 항체 및 자가면역 및 염증 질환을 치료하기 위한 이의 용도
|
IL310216A
(en)
|
2018-03-05 |
2024-03-01 |
Janssen Biotech Inc |
Methods for treating Crohn's disease with a specific anti-IL23 antibody
|
CA3093772C
(en)
|
2018-03-12 |
2024-04-16 |
Zoetis Services Llc |
Anti-ngf antibodies and methods thereof
|
BR112020018675A2
(pt)
|
2018-03-14 |
2021-01-05 |
Pioneer Hi-Bred International, Inc. |
Proteínas inseticidas de plantas e métodos para a sua utilização
|
CN111867377B
(zh)
|
2018-03-14 |
2023-05-23 |
先锋国际良种公司 |
来自植物的杀昆虫蛋白及其使用方法
|
EP3788377A1
(de)
|
2018-05-04 |
2021-03-10 |
Abbott Laboratories |
Hbv-diagnostische, prognostische und therapeutische verfahren und produkte
|
US11708571B2
(en)
|
2018-05-17 |
2023-07-25 |
Bp Corporation North America Inc. |
Production of 2-keto-3-deoxy-d-gluconic acid in filamentous fungi
|
AU2019282671B2
(en)
|
2018-06-08 |
2021-05-06 |
Crystal Bioscience Inc. |
Transgenic animal for producing diversified antibodies that have the same light chain i
|
US20210277118A1
(en)
|
2018-06-21 |
2021-09-09 |
Daiichi Sankyo Company, Limited |
Compositions including cd3 antigen binding fragments and uses thereof
|
WO2020014306A1
(en)
|
2018-07-10 |
2020-01-16 |
Immunogen, Inc. |
Met antibodies and immunoconjugates and uses thereof
|
JP2021530697A
(ja)
|
2018-07-18 |
2021-11-11 |
ヤンセン バイオテツク,インコーポレーテツド |
抗il23特異的抗体で治療した後の持続応答予測因子
|
WO2020041360A1
(en)
|
2018-08-21 |
2020-02-27 |
Quidel Corporation |
Dbpa antibodies and uses thereof
|
CN113412332A
(zh)
|
2018-09-07 |
2021-09-17 |
巴斯夫植物科学有限公司 |
用于在植物中产生高水平pufa的改进方法
|
CN112996915A
(zh)
|
2018-09-07 |
2021-06-18 |
巴斯夫植物科学有限公司 |
用于在植物中产生高水平pufa的改进方法
|
US20230183728A1
(en)
|
2018-09-07 |
2023-06-15 |
Basf Plant Science Company Gmbh |
Improved method for the production of high levels of pufa in plants
|
WO2020065532A1
(en)
|
2018-09-24 |
2020-04-02 |
Janssen Biotech, Inc. |
Safe and effective method of treating ulcerative colitis with anti-il12/il23 antibody
|
WO2020073004A1
(en)
|
2018-10-05 |
2020-04-09 |
Research Institute At Nationwide Children's Hospital |
Compositions and methods for enzymatic disruption of bacterial biofilms
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
US20220332800A1
(en)
|
2018-11-20 |
2022-10-20 |
Takeda Vaccines, Inc. |
Novel anti-zika virus antibodies and uses thereof
|
KR20210093973A
(ko)
|
2018-11-20 |
2021-07-28 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 안전하고 효과적인 방법
|
WO2020128864A1
(en)
|
2018-12-18 |
2020-06-25 |
Janssen Biotech, Inc. |
Safe and effective method of treating lupus with anti-il12/il23 antibody
|
WO2020132557A1
(en)
|
2018-12-21 |
2020-06-25 |
Compass Therapeutics Llc |
Transgenic mouse expressing common human light chain
|
EP3911676A1
(de)
|
2019-01-15 |
2021-11-24 |
Janssen Biotech, Inc. |
Anti-tnf-antikörperzusammensetzungen und verfahren zur behandlung von juveniler idiopathischer arthritis
|
AU2020210962A1
(en)
|
2019-01-23 |
2021-07-22 |
Janssen Biotech, Inc. |
anti-TNF antibody compositions for use in methods for the treatment of Psoriatic Arthritis
|
KR20210141990A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-il12/il23 항체 조성물을 생성하기 위한 제조 방법
|
WO2020183270A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Methods for producing anti-tnf antibody compositions
|
US20220153829A1
(en)
|
2019-03-14 |
2022-05-19 |
Janssen Biotech, Inc. |
Methods for Producing Anti-TNF Antibody Compositions
|
CA3133381A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
EP3941934A4
(de)
|
2019-03-18 |
2022-12-07 |
Janssen Biotech, Inc. |
Verfahren zur behandlung von psoriasis bei kindern mit anti-il12/il23-antikörper
|
WO2020227554A1
(en)
|
2019-05-09 |
2020-11-12 |
Genentech, Inc. |
Methods of making antibodies
|
BR112021023295A2
(pt)
|
2019-05-23 |
2022-02-08 |
Janssen Biotech Inc |
Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
|
WO2020245676A1
(en)
|
2019-06-03 |
2020-12-10 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
MX2021014882A
(es)
|
2019-06-03 |
2022-03-25 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y métodos para el tratamiento de la espondilitis anquilosante activa.
|
AU2020311897A1
(en)
|
2019-07-08 |
2022-02-03 |
Research Institute At Nationwide Children's Hospital |
Antibody compositions for disrupting biofilms
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
AU2020408213A1
(en)
|
2019-12-19 |
2022-06-23 |
Quidel Corporation |
Monoclonal antibody fusions
|
US20230041211A1
(en)
|
2019-12-20 |
2023-02-09 |
Basf Se |
Decreasing toxicity of terpenes and increasing the production potential in micro-organisms
|
US20230061973A1
(en)
|
2020-02-05 |
2023-03-02 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
EP4132971A1
(de)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinitätsgereifte anti-lap-antikörper und verwendungen davon
|
CA3175523A1
(en)
|
2020-04-13 |
2021-10-21 |
Antti Virtanen |
Methods, complexes and kits for detecting or determining an amount of a .beta.-coronavirus antibody in a sample
|
US20210340524A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
WO2021221782A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
US20230235310A1
(en)
|
2020-06-04 |
2023-07-27 |
Isobionics B.V. |
Synthetic santalene synthases
|
CN115867564A
(zh)
|
2020-07-14 |
2023-03-28 |
先锋国际良种公司 |
杀昆虫蛋白及其使用方法
|
WO2022029494A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Rapid Diagnostics International Unlimited Company |
Assays for detecting sars-cov-2
|
US20220043000A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Methods and kits for detecting sars-cov-2 protein in a sample
|
US11795225B2
(en)
|
2020-09-11 |
2023-10-24 |
Medimmune Limited |
Therapeutic binding molecules
|
KR20230066095A
(ko)
|
2020-09-12 |
2023-05-12 |
메디뮨 리미티드 |
항-b7h4 항체-약물 접합체 요법에 대한 점수산정 방법
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
CA3198161A1
(en)
|
2020-12-01 |
2022-06-09 |
Beth MCQUISTON |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
EP4015626A1
(de)
|
2020-12-18 |
2022-06-22 |
Isobionics B.V. |
Enzyme und verfahren zur fermentativen herstellung von monoterpenestern
|
EP4271998A1
(de)
|
2020-12-30 |
2023-11-08 |
Abbott Laboratories |
Verfahren zur bestimmung des sars-cov-2-antigens und anti-sars-cov-2-antikörpers in einer probe
|
MX2023008285A
(es)
|
2021-01-13 |
2023-09-12 |
Memorial Sloan Kettering Cancer Center |
Conjugado de anticuerpo anti-dll3-farmaco.
|
US20240115720A1
(en)
|
2021-01-13 |
2024-04-11 |
Memorial Sloan Kettering Cancer Center |
Antibody-pyrrolobenzodiazepine derivative conjugate
|
UY39610A
(es)
|
2021-01-20 |
2022-08-31 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
BR112023018353A2
(pt)
|
2021-03-12 |
2024-02-06 |
Janssen Biotech Inc |
Método seguro e eficaz para tratamento da artrite psoriática com anticorpo específico anti-il23
|
IL305836A
(en)
|
2021-03-12 |
2023-11-01 |
Janssen Biotech Inc |
A method for treating psoriatic arthritis patients with insufficient response to TNF therapy with a specific anti-IL23 antibody
|
BR112023017490A2
(pt)
|
2021-03-17 |
2023-11-07 |
Receptos Llc |
Métodos de tratamento de dermatite atópica com anticorpos anti il-13
|
KR20230158526A
(ko)
|
2021-03-18 |
2023-11-20 |
메디뮨 리미티드 |
Ccr9에 결합하는 치료용 결합 분자
|
EP4337689A1
(de)
|
2021-05-12 |
2024-03-20 |
Applied Biomedical Science Institute |
Bindungspolypeptide gegen sars cov-2 und verwendungen davon
|
WO2022245920A1
(en)
|
2021-05-18 |
2022-11-24 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
IL308607A
(en)
|
2021-05-20 |
2024-01-01 |
Janssen Biotech Inc |
A method for treating inflammatory bowel disease with combined treatment of antibodies to IL-23 and TNF alpha
|
JP2024521476A
(ja)
|
2021-06-14 |
2024-05-31 |
アボット・ラボラトリーズ |
音響エネルギー、電磁エネルギー、過圧波及び/又は爆風により引き起こされる脳損傷の診断法又は診断の一助となる方法
|
EP4367136A1
(de)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Herstellungsverfahren zur herstellung von anti-tnf-antikörperzusammensetzungen
|
IL309987A
(en)
|
2021-07-09 |
2024-03-01 |
Janssen Biotech Inc |
Production methods for the production of anti-IL12/IL23 antibody compositions
|
KR20240032991A
(ko)
|
2021-07-09 |
2024-03-12 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 생성을 위한 제조 방법
|
WO2023012111A2
(en)
|
2021-08-02 |
2023-02-09 |
Basf Se |
Novel production of aroma compounds with ionylideneethane synthases
|
US11807685B2
(en)
|
2021-08-05 |
2023-11-07 |
The Uab Research Foundation |
Anti-CD47 antibody and uses thereof
|
WO2023028186A1
(en)
|
2021-08-27 |
2023-03-02 |
Abbott Laboratories |
Methods for detecting immunoglobulin g, subclass 4 (igg4) in a biological sample
|
EP4396587A1
(de)
|
2021-08-31 |
2024-07-10 |
Abbott Laboratories |
Verfahren und systeme zur diagnose von hirnverletzungen
|
WO2023056268A1
(en)
|
2021-09-30 |
2023-04-06 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
CA3236779A1
(en)
|
2021-10-29 |
2023-05-04 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
IL312778A
(en)
|
2021-11-15 |
2024-07-01 |
Janssen Biotech Inc |
Methods for treating Crohn's disease with a specific anti-IL23 antibody
|
IL313021A
(en)
|
2021-11-23 |
2024-07-01 |
Janssen Biotech Inc |
A method for treating ulcerative colitis with a specific anti-IL23 antibody
|
AU2022413677A1
(en)
|
2021-12-17 |
2024-06-27 |
Abbott Laboratories |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
WO2023129942A1
(en)
|
2021-12-28 |
2023-07-06 |
Abbott Laboratories |
Use of biomarkers to determine sub-acute traumatic brain injury (tbi) in a subject having received a head computerized tomography (ct) scan that is negative for a tbi or no head ct scan
|
AU2023216317A1
(en)
|
2022-02-04 |
2024-09-05 |
Abbott Laboratories |
Lateral flow methods, assays, and devices for detecting the presence or measuring the amount of ubiquitin carboxy-terminal hydrolase l1 and/or glial fibrillary acidic protein in a sample
|
TW202348252A
(zh)
|
2022-02-16 |
2023-12-16 |
英商梅迪繆思有限公司 |
用治療性結合分子治療癌症的組合療法
|
US20230312703A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of Treating Psoriasis with IL-23 Specific Antibody
|
WO2023223265A1
(en)
|
2022-05-18 |
2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
|
WO2024006876A1
(en)
|
2022-06-29 |
2024-01-04 |
Abbott Laboratories |
Magnetic point-of-care systems and assays for determining gfap in biological samples
|
WO2024059708A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
WO2024059692A1
(en)
|
2022-09-15 |
2024-03-21 |
Abbott Laboratories |
Hbv diagnostic, prognostic, and therapeutic methods and products
|
US20240199734A1
(en)
|
2022-11-22 |
2024-06-20 |
Janssen Biotech, Inc. |
Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
|