IL159080A0 - Dry powder inhalation system for transpulmonary administration - Google Patents
Dry powder inhalation system for transpulmonary administrationInfo
- Publication number
- IL159080A0 IL159080A0 IL15908002A IL15908002A IL159080A0 IL 159080 A0 IL159080 A0 IL 159080A0 IL 15908002 A IL15908002 A IL 15908002A IL 15908002 A IL15908002 A IL 15908002A IL 159080 A0 IL159080 A0 IL 159080A0
- Authority
- IL
- Israel
- Prior art keywords
- dry powder
- powder inhalation
- inhalation system
- transpulmonary administration
- transpulmonary
- Prior art date
Links
- 239000000843 powder Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
- A61M15/0036—Piercing means hollow piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/004—Details of the piercing or cutting means with fixed piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/07—General characteristics of the apparatus having air pumping means
- A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/07—General characteristics of the apparatus having air pumping means
- A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
- A61M2205/075—Bulb type
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001182504 | 2001-06-15 | ||
| JP2001400871 | 2001-12-28 | ||
| JP2002111131 | 2002-04-12 | ||
| PCT/JP2002/005955 WO2002102445A1 (en) | 2001-06-15 | 2002-06-14 | Dry powder inhalation system for transpulmonary administration |
| JP2002363158 | 2002-12-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL159080A0 true IL159080A0 (en) | 2004-05-12 |
Family
ID=32931499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15908002A IL159080A0 (en) | 2001-06-15 | 2002-06-14 | Dry powder inhalation system for transpulmonary administration |
Country Status (32)
| Country | Link |
|---|---|
| US (4) | US7448379B2 (cs) |
| EP (4) | EP1402913B1 (cs) |
| JP (1) | JP3635353B2 (cs) |
| KR (3) | KR100906754B1 (cs) |
| CN (2) | CN100427077C (cs) |
| AP (1) | AP1861A (cs) |
| AT (1) | ATE336989T1 (cs) |
| AU (3) | AU2002311213B2 (cs) |
| BG (1) | BG108517A (cs) |
| BR (2) | BR0210425B1 (cs) |
| CA (2) | CA2449954C (cs) |
| CY (1) | CY1105755T1 (cs) |
| CZ (1) | CZ200470A3 (cs) |
| DE (1) | DE60214184T2 (cs) |
| DK (1) | DK1402913T3 (cs) |
| EA (1) | EA005025B1 (cs) |
| EE (1) | EE04956B1 (cs) |
| EG (2) | EG24184A (cs) |
| ES (1) | ES2271266T3 (cs) |
| HR (2) | HRP20040033B8 (cs) |
| HU (1) | HU227300B1 (cs) |
| IL (1) | IL159080A0 (cs) |
| MA (1) | MA27131A1 (cs) |
| MX (1) | MXPA05006322A (cs) |
| NO (2) | NO334652B1 (cs) |
| NZ (2) | NZ530044A (cs) |
| PL (2) | PL205104B1 (cs) |
| PT (1) | PT1402913E (cs) |
| SI (1) | SI1402913T1 (cs) |
| TW (1) | TW570819B (cs) |
| UA (1) | UA81280C2 (cs) |
| WO (2) | WO2002102445A1 (cs) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| EG24184A (en) * | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| GB2380410B (en) * | 2001-10-05 | 2003-11-19 | Alchemy Healthcare Ltd | Apparatus for the nasal or oral delivery of a medicament |
| ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
| USD514698S1 (en) * | 2002-10-07 | 2006-02-07 | Cadila Healthcare Limited | Inhalation device for the delivery and storage of powdered medicaments |
| WO2004054605A1 (en) * | 2002-12-13 | 2004-07-01 | Otsuka Pharmaceutical Co., Ltd. | Freeze-dried interferon-ϝ composition for transpulmonary administration and inhalation system therefor |
| JP4562528B2 (ja) * | 2002-12-13 | 2010-10-13 | 大塚製薬株式会社 | 経肺投与用の吸入式デバイス |
| US20040187866A1 (en) * | 2003-03-31 | 2004-09-30 | Nathaniel Hughes | Liquid medicament delivery system |
| GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
| JP5183068B2 (ja) * | 2003-12-22 | 2013-04-17 | フィンレイ,ウォーレン,エイチ | 大気噴出凍結乾燥法による粉末形成 |
| EP1593376A1 (en) * | 2004-05-04 | 2005-11-09 | Warner-Lambert Company LLC | Improved pullulan capsules |
| US20060021613A1 (en) * | 2004-08-02 | 2006-02-02 | Robert Overlander | Accessory for nebulizer inhaler system |
| BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
| CN104436170B (zh) | 2004-08-23 | 2018-02-23 | 曼金德公司 | 用于药物输送的二酮哌嗪盐 |
| JP5188183B2 (ja) * | 2004-11-10 | 2013-04-24 | シプラ・リミテッド | 吸入器 |
| FR2877925B1 (fr) * | 2004-11-16 | 2008-09-19 | Valois Sas | Dispositif de distribution de produit fluide. |
| DE102005016230A1 (de) * | 2005-04-08 | 2006-10-19 | Altana Pharma Ag | Vorrichtung zur Trockenvernebelung |
| WO2007007110A1 (en) * | 2005-07-13 | 2007-01-18 | Cipla Limited | Inhaler device |
| DE102005038619A1 (de) * | 2005-08-16 | 2007-02-22 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments |
| AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
| KR100777249B1 (ko) * | 2006-02-14 | 2007-11-28 | (주)바이오니아 | 건조 올리고뉴클레오티드 조성물 및 이의 제조 방법 |
| JP5599975B2 (ja) | 2006-02-22 | 2014-10-01 | マンカインド コーポレイション | ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法 |
| DE102006010089A1 (de) * | 2006-02-24 | 2007-10-18 | Aha-Kunststofftechnik Gmbh | Trockenpulver-Inhalator |
| WO2007103152A2 (en) * | 2006-03-03 | 2007-09-13 | Stc.Unm | Dry powder inhaler with aeroelastic dispersion mechanism |
| US7832399B2 (en) * | 2006-03-10 | 2010-11-16 | One Dose, Llc | Medication inhaler |
| US8360057B2 (en) * | 2006-03-10 | 2013-01-29 | Dose One, Llc | Medication inhaler for dispensing multiple capsules |
| EP2043717A1 (en) * | 2006-07-14 | 2009-04-08 | Astra Zeneca AB | Inhalation system and delivery device for the administration of a drug in the form of dry powder |
| DE102006047668B3 (de) * | 2006-09-28 | 2008-04-24 | Ing. Erich Pfeiffer Gmbh | Inhalationsvorrichtung |
| AU2008225501B2 (en) * | 2007-03-09 | 2013-08-29 | Otsuka Pharmaceutical Co., Ltd. | Lyophilized preparation comprising influenza vaccine, and method for preparation thereof |
| US9179691B2 (en) | 2007-12-14 | 2015-11-10 | Aerodesigns, Inc. | Delivering aerosolizable food products |
| EP2224984A4 (en) | 2007-12-20 | 2013-10-30 | Astrazeneca Ab | DISPENSER AND METHOD FOR DRIVING POWDER IN AIR FLOW 537 |
| US8499757B2 (en) | 2008-06-13 | 2013-08-06 | Mannkind Corporation | Dry powder inhaler and system for drug delivery |
| USD605752S1 (en) | 2008-06-13 | 2009-12-08 | Mannkind Corporation | Dry powder inhaler |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| USD635241S1 (en) | 2008-06-13 | 2011-03-29 | Mannkind Corporation | Dry powder inhaler |
| ES2904623T3 (es) | 2008-06-20 | 2022-04-05 | Mannkind Corp | Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| TWI528982B (zh) * | 2009-03-04 | 2016-04-11 | 曼凱公司 | 改良的乾粉藥物輸送系統 |
| US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| CN101884593B (zh) * | 2009-05-14 | 2013-09-18 | 许清萍 | 由高剂量冻干制剂调配液态制剂的方法 |
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| US8925726B2 (en) | 2011-04-01 | 2015-01-06 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| ES2708218T3 (es) * | 2011-08-01 | 2019-04-09 | Univ Monash | Método y formulación para inhalación |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| DE102012103000A1 (de) * | 2012-04-05 | 2013-10-10 | Rpc Formatec Gmbh | Spender zur Ausbringung einer insbesondere körnigen oder pulverförmigen Substanz und Verfahren zur Entleerung einer Substanz-Aufnahme |
| MX354163B (es) | 2012-07-12 | 2018-02-15 | Mannkind Corp | Sistemas y métodos de suministro de fármaco en polvo seco. |
| EP2708219A1 (en) * | 2012-09-12 | 2014-03-19 | PARI Pharma GmbH | Opening element for opening an ampoule in an aerosol generation device and aerosol generation device comprising the opening element |
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