HUP0203568A2 - Vírusellenes készítmények - Google Patents

Vírusellenes készítmények

Info

Publication number
HUP0203568A2
HUP0203568A2 HU0203568A HUP0203568A HUP0203568A2 HU P0203568 A2 HUP0203568 A2 HU P0203568A2 HU 0203568 A HU0203568 A HU 0203568A HU P0203568 A HUP0203568 A HU P0203568A HU P0203568 A2 HUP0203568 A2 HU P0203568A2
Authority
HU
Hungary
Prior art keywords
antiviral compounds
mixture
melt
antiviral compositions
milling
Prior art date
Application number
HU0203568A
Other languages
English (en)
Inventor
Lieven Baert
Geert Verreck
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HUP0203568A2 publication Critical patent/HUP0203568A2/hu
Publication of HUP0203568A3 publication Critical patent/HUP0203568A3/hu
Publication of HU228449B1 publication Critical patent/HU228449B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány vírusellenes vegyületeket tartalmazó gyógyászatikészítményekre vonatkozik, amelyek vírusfertőzéstől szenvedő emlősnek,közelebbről embernek adagolhatók. Ezek a készítmények olyanrészecskéket tartalmaznak, amelyek egy vagy több meghatározottvírusellenes vegyület és egy vagy több megfelelő, vízoldható polimerkeverékének ömledék-extrudálásával, és azt követően az ömledék-extrudált keverék őrlésével vannak előállítva. Ó
HU0203568A 1999-09-24 2000-08-31 Antiviral compositions HU228449B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203128 1999-09-24
PCT/EP2000/008522 WO2001022938A1 (en) 1999-09-24 2000-08-31 Antiviral compositions

Publications (3)

Publication Number Publication Date
HUP0203568A2 true HUP0203568A2 (hu) 2003-02-28
HUP0203568A3 HUP0203568A3 (en) 2006-07-28
HU228449B1 HU228449B1 (en) 2013-03-28

Family

ID=8240674

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203568A HU228449B1 (en) 1999-09-24 2000-08-31 Antiviral compositions

Country Status (35)

Country Link
US (4) US7241458B1 (hu)
EP (1) EP1225874B1 (hu)
JP (1) JP4919566B2 (hu)
KR (2) KR100820605B1 (hu)
CN (1) CN1234347C (hu)
AP (1) AP1639A (hu)
AT (1) ATE316781T1 (hu)
AU (2) AU775360B2 (hu)
BG (1) BG65754B1 (hu)
BR (1) BRPI0014271B1 (hu)
CA (1) CA2384188C (hu)
CY (1) CY1105268T1 (hu)
CZ (1) CZ300712B6 (hu)
DE (1) DE60025837T2 (hu)
DK (1) DK1225874T3 (hu)
EA (1) EA005423B1 (hu)
EE (1) EE04991B1 (hu)
ES (1) ES2258018T3 (hu)
HK (1) HK1048768B (hu)
HR (1) HRP20020247B1 (hu)
HU (1) HU228449B1 (hu)
IL (1) IL148801A0 (hu)
IS (1) IS2567B (hu)
MX (1) MXPA02003182A (hu)
NO (1) NO333358B1 (hu)
NZ (1) NZ517025A (hu)
OA (1) OA12029A (hu)
PL (1) PL207590B1 (hu)
PT (1) PT1225874E (hu)
SI (1) SI1225874T1 (hu)
SK (1) SK285240B6 (hu)
TR (1) TR200200763T2 (hu)
UA (1) UA74797C2 (hu)
WO (1) WO2001022938A1 (hu)
ZA (1) ZA200202289B (hu)

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