HK6392A - Podophyllotoxin derivatives - Google Patents

Podophyllotoxin derivatives Download PDF

Info

Publication number
HK6392A
HK6392A HK63/92A HK6392A HK6392A HK 6392 A HK6392 A HK 6392A HK 63/92 A HK63/92 A HK 63/92A HK 6392 A HK6392 A HK 6392A HK 6392 A HK6392 A HK 6392A
Authority
HK
Hong Kong
Prior art keywords
substd
alkyl
opt
aralkyl
cycloalkyl
Prior art date
Application number
HK63/92A
Other languages
English (en)
Inventor
G Saulnier Mark
D Senter Peter
F Kadow John
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of HK6392A publication Critical patent/HK6392A/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Cable Accessories (AREA)
HK63/92A 1987-08-04 1992-01-16 Podophyllotoxin derivatives HK6392A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8149387A 1987-08-04 1987-08-04
US07/199,731 US4904768A (en) 1987-08-04 1988-05-27 Epipodophyllotoxin glucoside 4'-phosphate derivatives

Publications (1)

Publication Number Publication Date
HK6392A true HK6392A (en) 1992-01-17

Family

ID=26765636

Family Applications (1)

Application Number Title Priority Date Filing Date
HK63/92A HK6392A (en) 1987-08-04 1992-01-16 Podophyllotoxin derivatives

Country Status (34)

Country Link
US (3) US4904768A (cs)
JP (1) JPH0699465B2 (cs)
KR (1) KR900006230B1 (cs)
CN (1) CN1027169C (cs)
AT (1) AT398974B (cs)
BE (1) BE1002982A4 (cs)
CA (1) CA1310637C (cs)
CH (1) CH676716A5 (cs)
CY (1) CY1625A (cs)
CZ (1) CZ286893B6 (cs)
DD (2) DD299067A5 (cs)
DE (1) DE3826562A1 (cs)
DK (2) DK169344B1 (cs)
ES (1) ES2010775A6 (cs)
FI (1) FI87790C (cs)
FR (1) FR2622193B1 (cs)
GB (1) GB2207674B (cs)
GR (1) GR1000490B (cs)
HK (1) HK6392A (cs)
HU (3) HU208147B (cs)
IE (1) IE61040B1 (cs)
IL (1) IL87290A (cs)
IT (1) IT1226825B (cs)
LU (2) LU87290A1 (cs)
MX (1) MX173843B (cs)
MY (1) MY104321A (cs)
NL (2) NL192683C (cs)
NO (4) NO170284C (cs)
NZ (1) NZ225615A (cs)
PT (1) PT88186B (cs)
SE (1) SE502214C2 (cs)
SG (1) SG101291G (cs)
SK (1) SK541288A3 (cs)
YU (3) YU143688A (cs)

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US7241595B2 (en) 1989-10-20 2007-07-10 Sanofi-Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US6475486B1 (en) 1990-10-18 2002-11-05 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US5552154A (en) 1989-11-06 1996-09-03 The Stehlin Foundation For Cancer Research Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides
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US5648474A (en) * 1991-10-08 1997-07-15 Bristol-Myers Squibb Crystalline etoposide 4'-phosphate diethanolate
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US6080751A (en) * 1992-01-14 2000-06-27 The Stehlin Foundation For Cancer Research Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof
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US20050009759A1 (en) * 2001-10-26 2005-01-13 Claude Monneret Derivatives of etoposide and analogs, and pharmaceutical compositions containing them
EP2283869A3 (en) 2002-07-15 2012-06-27 Board of Regents, The University of Texas System Selected antibodies and duramycin peptides binding to anionic phospholipids and aminophospholipids and their use in the treatment of viral infections and cancer
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CN100334090C (zh) * 2005-02-02 2007-08-29 南京医科大学 吡啶类鬼臼毒素化合物及其制备方法和在制备杀虫剂中的应用
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FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
EP0111058B1 (en) * 1982-11-26 1987-11-04 Nippon Kayaku Kabushiki Kaisha Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
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Also Published As

Publication number Publication date
DK11992D0 (da) 1992-01-31
PT88186B (pt) 1995-07-03
AU610619B2 (en) 1991-05-23
SE502214C2 (sv) 1995-09-18
GB2207674B (en) 1991-09-11
SE8802815L (sv) 1989-02-05
NO883299D0 (no) 1988-07-26
YU10390A (en) 1990-06-30
FI883596A0 (fi) 1988-08-01
IL87290A (en) 1993-01-31
CN1027169C (zh) 1994-12-28
KR900006230B1 (ko) 1990-08-27
CY1625A (en) 1992-07-10
IE61040B1 (en) 1994-09-07
GB2207674A (en) 1989-02-08
NL192683C (nl) 1997-12-02
DE3826562A1 (de) 1989-02-16
DE3826562C2 (cs) 1993-04-08
GR880100512A (en) 1989-05-25
NL970042I2 (cs) 2005-06-01
US4904768A (en) 1990-02-27
CA1310637C (en) 1992-11-24
GR1000490B (el) 1992-07-30
DK11992A (da) 1992-01-31
SK279325B6 (sk) 1998-10-07
USRE35524E (en) 1997-06-03
NO172440B (no) 1993-04-13
FI87790B (fi) 1992-11-13
FR2622193B1 (fr) 1993-12-17
NL8801934A (nl) 1989-03-01
DK434088A (da) 1989-02-05
DK434088D0 (da) 1988-08-03
JPH0699465B2 (ja) 1994-12-07
NO920665D0 (no) 1992-02-20
IL87290A0 (en) 1989-01-31
YU143688A (en) 1990-04-30
LU90138I2 (fr) 1997-11-26
FI87790C (fi) 1993-02-25
NZ225615A (en) 1991-06-25
LU87290A1 (fr) 1990-02-07
CZ286893B6 (cs) 2000-07-12
NO920277L (no) 1989-02-24
CN1061225A (zh) 1992-05-20
NL970042I1 (nl) 1998-03-02
DD299067A5 (de) 1992-03-26
SG101291G (en) 1992-01-17
HU905862D0 (en) 1991-03-28
SE8802815D0 (sv) 1988-08-03
NO170284B (no) 1992-06-22
HU211960A9 (en) 1996-01-29
DD274423A5 (de) 1989-12-20
IT1226825B (it) 1991-02-19
HU202547B (en) 1991-03-28
CZ541288A3 (cs) 1999-12-15
HUT47303A (en) 1989-02-28
FR2622193A1 (fr) 1989-04-28
NO1998002I1 (no) 1998-01-14
SK541288A3 (en) 1998-10-07
PT88186A (pt) 1989-06-30
MY104321A (en) 1994-03-31
NO172440C (no) 1993-07-21
MX9202851A (es) 1992-06-30
IT8821535A0 (it) 1988-07-28
NO170284C (no) 1992-09-30
FI883596A7 (fi) 1989-02-05
NO920665L (no) 1989-02-24
AT398974B (de) 1995-02-27
GB8818462D0 (en) 1988-09-07
JPH01100188A (ja) 1989-04-18
HU208147B (en) 1993-08-30
ES2010775A6 (es) 1989-12-01
CH676716A5 (cs) 1991-02-28
DK169344B1 (da) 1994-10-10
AU2030688A (en) 1989-06-08
NO883299L (no) 1989-02-24
KR890003790A (ko) 1989-04-18
US5041424A (en) 1991-08-20
BE1002982A4 (fr) 1991-10-15
ATA195588A (de) 1994-07-15
MX173843B (es) 1994-03-30
NO920277D0 (no) 1992-01-22
IE882378L (en) 1989-02-04
NL192683B (cs) 1997-08-01
YU10490A (en) 1990-06-30

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Effective date: 20080802