HK1251237A1 - 提高含fc區多肽純化效率的方法 - Google Patents

提高含fc區多肽純化效率的方法

Info

Publication number
HK1251237A1
HK1251237A1 HK18110553.8A HK18110553A HK1251237A1 HK 1251237 A1 HK1251237 A1 HK 1251237A1 HK 18110553 A HK18110553 A HK 18110553A HK 1251237 A1 HK1251237 A1 HK 1251237A1
Authority
HK
Hong Kong
Prior art keywords
purification
region
containing polypeptide
promoting efficiency
promoting
Prior art date
Application number
HK18110553.8A
Other languages
English (en)
Inventor
田中信幸
百瀨瑠美子
Original Assignee
中外制藥株式會社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 中外制藥株式會社 filed Critical 中外制藥株式會社
Publication of HK1251237A1 publication Critical patent/HK1251237A1/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/526CH3 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/528CH4 domain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK18110553.8A 2015-12-28 2018-08-16 提高含fc區多肽純化效率的方法 HK1251237A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015255726 2015-12-28
PCT/JP2016/088820 WO2017115773A1 (ja) 2015-12-28 2016-12-27 Fc領域含有ポリペプチドの精製を効率化するための方法

Publications (1)

Publication Number Publication Date
HK1251237A1 true HK1251237A1 (zh) 2019-01-25

Family

ID=59224731

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18110553.8A HK1251237A1 (zh) 2015-12-28 2018-08-16 提高含fc區多肽純化效率的方法

Country Status (13)

Country Link
US (1) US11649262B2 (zh)
EP (1) EP3398965A4 (zh)
JP (2) JP7219005B2 (zh)
KR (1) KR20180091918A (zh)
CN (1) CN108368166B (zh)
AU (1) AU2016381992B2 (zh)
BR (1) BR112018009312A8 (zh)
CA (1) CA3004288A1 (zh)
HK (1) HK1251237A1 (zh)
IL (1) IL259247B2 (zh)
MX (1) MX2018007781A (zh)
SG (1) SG11201803989WA (zh)
WO (1) WO2017115773A1 (zh)

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TWI682995B (zh) 2009-03-19 2020-01-21 日商中外製藥股份有限公司 抗體恆定區域改變體
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