HK1210221A1 - Method for sequence manipulation, optimized guiding composition and system engineering - Google Patents

Method for sequence manipulation, optimized guiding composition and system engineering Download PDF

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Publication number
HK1210221A1
HK1210221A1 HK15111023.1A HK15111023A HK1210221A1 HK 1210221 A1 HK1210221 A1 HK 1210221A1 HK 15111023 A HK15111023 A HK 15111023A HK 1210221 A1 HK1210221 A1 HK 1210221A1
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HK
Hong Kong
Prior art keywords
sequence
crispr
target
tracr
polynucleotide
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HK15111023.1A
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English (en)
Chinese (zh)
Inventor
Feng Zhang
Le Cong
Patrick Hsu
Fei RAN
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The Broad Institute, Inc.
Massachusetts Institute Of Technology
President And Fellows Of Harvard College
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49920627&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1210221(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Broad Institute, Inc., Massachusetts Institute Of Technology, President And Fellows Of Harvard College filed Critical The Broad Institute, Inc.
Publication of HK1210221A1 publication Critical patent/HK1210221A1/en

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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HK15111023.1A 2012-12-12 2015-11-09 Method for sequence manipulation, optimized guiding composition and system engineering HK1210221A1 (en)

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
US201261736527P 2012-12-12 2012-12-12
US201261736527P 2012-12-12
US201361748427P 2013-01-02 2013-01-02
US201361748427P 2013-01-02
US201361758468P 2013-01-30 2013-01-30
US201361758468P 2013-01-30
US201361769046P 2013-02-25 2013-02-25
US201361769046P 2013-02-25
US201361802174P 2013-03-15 2013-03-15
US201361791409P 2013-03-15 2013-03-15
US201361802174P 2013-03-15
US201361791409P 2013-03-15
US201361806375P 2013-03-28 2013-03-28
US201361806375P 2013-03-28
US201361814263P 2013-04-20 2013-04-20
US201361814263P 2013-04-20
US201361819803P 2013-05-06 2013-05-06
US201361819803P 2013-05-06
US201361828130P 2013-05-28 2013-05-28
US201361828130P 2013-05-28
US201361836127P 2013-06-17 2013-06-17
US201361835931P 2013-06-17 2013-06-17
US201361835931P 2013-06-17
US201361836127P 2013-06-17

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US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
BR112013024337A2 (pt) 2011-03-23 2017-09-26 Du Pont locus de traço transgênico complexo em uma planta, planta ou semente, método para produzir em uma planta um locus de traço transgênico complexo e construto de expressão
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