EP2734621B1
(de)
|
2011-07-22 |
2019-09-04 |
President and Fellows of Harvard College |
Beurteilung und verbesserung einer nukleasespaltungsspezifität
|
US11021737B2
(en)
|
2011-12-22 |
2021-06-01 |
President And Fellows Of Harvard College |
Compositions and methods for analyte detection
|
GB201122458D0
(en)
|
2011-12-30 |
2012-02-08 |
Univ Wageningen |
Modified cascade ribonucleoproteins and uses thereof
|
US9637739B2
(en)
*
|
2012-03-20 |
2017-05-02 |
Vilnius University |
RNA-directed DNA cleavage by the Cas9-crRNA complex
|
DK2847335T3
(en)
|
2012-04-25 |
2018-08-13 |
Regeneron Pharma |
NUCLEASED MEDIUM TARGETING WITH LARGE TARGET VECTORS
|
EP2841572B1
(de)
|
2012-04-27 |
2019-06-19 |
Duke University |
Genetische korrektur mutierter gene
|
ES2728782T3
(es)
|
2012-05-25 |
2019-10-28 |
Univ California |
Métodos y composiciones para la modificación de ADN objetivo dirigida por ARN y para la modulación de la transcripción dirigida por ARN
|
BR112014031891A2
(pt)
|
2012-06-19 |
2017-08-01 |
Univ Minnesota |
direcionamento genético nas plantas utilizando vírus de dna
|
DK3196301T3
(en)
|
2012-07-11 |
2019-01-14 |
Sangamo Therapeutics Inc |
METHODS AND COMPOSITIONS FOR TREATING MONOGENIC DISEASES
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
EP3494997B1
(de)
*
|
2012-07-25 |
2019-09-18 |
The Broad Institute, Inc. |
Induzierbare dns-bindende proteine und genomperturbationstools sowie anwendungen davon
|
CN114891871A
(zh)
|
2012-08-14 |
2022-08-12 |
10X基因组学有限公司 |
微胶囊组合物及方法
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10584381B2
(en)
|
2012-08-14 |
2020-03-10 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
CN116064532A
(zh)
|
2012-10-23 |
2023-05-05 |
基因工具股份有限公司 |
用于切割靶dna的组合物及其用途
|
DK3502240T3
(da)
|
2012-11-27 |
2021-08-09 |
Childrens Medical Ct Corp |
Målretning af distale bcl11a-reguleringselementer til føtal hæmoglobinreinduktion
|
KR102243092B1
(ko)
|
2012-12-06 |
2021-04-22 |
시그마-알드리치 컴퍼니., 엘엘씨 |
Crispr-기초된 유전체 변형과 조절
|
EP4286404A3
(de)
|
2012-12-12 |
2024-02-14 |
The Broad Institute Inc. |
Systeme, verfahren und zusammensetzungen mit crispr-cas-komponenten zur sequenzmanipulation
|
AU2013359212B2
(en)
|
2012-12-12 |
2017-01-19 |
Massachusetts Institute Of Technology |
Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
|
EP2931892B1
(de)
|
2012-12-12 |
2018-09-12 |
The Broad Institute, Inc. |
Verfahren, modelle, systeme und vorrichtungen zur identifikation von zielsequenzen für cas-enzyme oder crispr-cas-systeme für zielsequenzen und förderresultate davon
|
ES2576128T3
(es)
|
2012-12-12 |
2016-07-05 |
The Broad Institute, Inc. |
Modificación por tecnología genética y optimización de sistemas, métodos y composiciones para la manipulación de secuencias con dominios funcionales
|
IL307735A
(en)
*
|
2012-12-12 |
2023-12-01 |
Broad Inst Inc |
Systems engineering, methods and optimal guiding components for sequence manipulation
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
EP3064585B1
(de)
|
2012-12-12 |
2020-02-05 |
The Broad Institute, Inc. |
Technische bearbeitung und optimierung von verbesserten systemen, verfahren und enzymzusammensetzungen zur sequenzenmanipulation
|
DK3327127T3
(da)
|
2012-12-12 |
2021-06-28 |
Broad Inst Inc |
Fremføring, modificering og optimering af systemer, fremgangsmåder og sammensætninger til sekvensmanipulation og terapeutiske anvendelser
|
EP2931919B1
(de)
|
2012-12-14 |
2019-02-20 |
10X Genomics, Inc. |
Verfahren und systeme zur verarbeitung von polynukleotiden
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
IL308158A
(en)
*
|
2012-12-17 |
2023-12-01 |
Harvard College |
RNA-guided human genome engineering
|
AU2014207618A1
(en)
|
2013-01-16 |
2015-08-06 |
Emory University |
Cas9-nucleic acid complexes and uses related thereto
|
EP2954065B1
(de)
|
2013-02-08 |
2021-07-28 |
10X Genomics, Inc. |
Partitionierung und verarbeitung von analyten und andere arten
|
EP3578666A1
(de)
|
2013-03-12 |
2019-12-11 |
President and Fellows of Harvard College |
Verfahren zur erzeugung einer dreidimensionalen nukleinsäure mit matrix
|
CN105980575A
(zh)
*
|
2013-03-14 |
2016-09-28 |
卡里布生物科学公司 |
以核酸为靶的核酸的组合物和方法
|
US9234213B2
(en)
|
2013-03-15 |
2016-01-12 |
System Biosciences, Llc |
Compositions and methods directed to CRISPR/Cas genomic engineering systems
|
US10760064B2
(en)
|
2013-03-15 |
2020-09-01 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
JP6980380B2
(ja)
*
|
2013-03-15 |
2021-12-15 |
ザ ジェネラル ホスピタル コーポレイション |
短縮ガイドRNA(tru−gRNA)を用いたRNA誘導型ゲノム編集の特異性の増大
|
AU2014227831B2
(en)
*
|
2013-03-15 |
2020-01-30 |
Regents Of The University Of Minnesota |
Engineering plant genomes using CRISPR/Cas systems
|
WO2014165825A2
(en)
|
2013-04-04 |
2014-10-09 |
President And Fellows Of Harvard College |
Therapeutic uses of genome editing with crispr/cas systems
|
PL3456831T3
(pl)
|
2013-04-16 |
2021-12-06 |
Regeneron Pharmaceuticals, Inc. |
Ukierunkowana modyfikacja genomu szczura
|
US9267135B2
(en)
|
2013-06-04 |
2016-02-23 |
President And Fellows Of Harvard College |
RNA-guided transcriptional regulation
|
MX2015016798A
(es)
|
2013-06-04 |
2016-10-26 |
Harvard College |
Regulacion transcripcional guiada por acido ribonucleico.
|
DK3011031T3
(da)
|
2013-06-17 |
2020-12-21 |
Broad Inst Inc |
Fremføring og anvendelse af crispr-cas-systemerne, vektorer og sammensætninger til levermålretning og -terapi
|
WO2014204729A1
(en)
|
2013-06-17 |
2014-12-24 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using viral components
|
EP4245853A3
(de)
|
2013-06-17 |
2023-10-18 |
The Broad Institute, Inc. |
Optimierte crispr-cas-doppel-nickase-systeme, verfahren und zusammensetzungen zur sequenzmanipulation
|
EP3011033B1
(de)
|
2013-06-17 |
2020-02-19 |
The Broad Institute, Inc. |
Funktionale genomik unter verwendung von crispr-cas-systemen, zusammensetzungen, verfahren, schirme und anwendungen davon
|
CA2915834A1
(en)
|
2013-06-17 |
2014-12-24 |
Massachusetts Institute Of Technology |
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
|
WO2014202250A1
(en)
|
2013-06-19 |
2014-12-24 |
Kolibree |
Toothbrush system with sensors for a dental hygiene monitoring system
|
US10011850B2
(en)
|
2013-06-21 |
2018-07-03 |
The General Hospital Corporation |
Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing
|
JP2016528890A
(ja)
*
|
2013-07-09 |
2016-09-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
CRISPR/Cas系を用いるゲノム編集の治療用の使用
|
DK3019619T3
(da)
*
|
2013-07-11 |
2021-10-11 |
Modernatx Inc |
Sammensætninger, der omfatter syntetiske polynukleotider, som koder for crispr-beslægtede proteiner, og syntetiske sgrna'er, og anvendelsesfremgangsmåder
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
ES2729635T3
(es)
|
2013-08-22 |
2019-11-05 |
Pioneer Hi Bred Int |
Modificación genómica usando sistemas de polinucleótido guía/endonucleasa Cas y métodos de uso
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
US9737604B2
(en)
|
2013-09-06 |
2017-08-22 |
President And Fellows Of Harvard College |
Use of cationic lipids to deliver CAS9
|
DE202014010413U1
(de)
|
2013-09-18 |
2015-12-08 |
Kymab Limited |
Zellen und Organismen
|
WO2015054507A1
(en)
|
2013-10-10 |
2015-04-16 |
Pronutria, Inc. |
Nutritive polypeptide production systems, and methods of manufacture and use thereof
|
WO2015065964A1
(en)
|
2013-10-28 |
2015-05-07 |
The Broad Institute Inc. |
Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof
|
PT3066201T
(pt)
|
2013-11-07 |
2018-06-04 |
Massachusetts Inst Technology |
Métodos e composições relacionadas com crispr com arng reguladores
|
RU2685914C1
(ru)
|
2013-12-11 |
2019-04-23 |
Регенерон Фармасьютикалс, Инк. |
Способы и композиции для направленной модификации генома
|
WO2015089364A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Crystal structure of a crispr-cas system, and uses thereof
|
EP3080260B1
(de)
|
2013-12-12 |
2019-03-06 |
The Broad Institute, Inc. |
Crispr-cas-systeme und verfahren zur veränderung der expression von genprodukten, strukturelle informationen und induzierbare modulare cas-enzyme
|
WO2015089486A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
WO2015089351A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
KR20160089530A
(ko)
|
2013-12-12 |
2016-07-27 |
더 브로드 인스티튜트, 인코퍼레이티드 |
Hbv 및 바이러스 질병 및 질환을 위한 crisprcas 시스템 및 조성물의 전달,용도 및 치료적 적용
|
AU2014361781B2
(en)
|
2013-12-12 |
2021-04-01 |
Massachusetts Institute Of Technology |
Delivery, use and therapeutic applications of the CRISPR -Cas systems and compositions for genome editing
|
US20150165054A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting caspase-9 point mutations
|
WO2015089419A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
|
WO2015089473A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
CN111705365A
(zh)
|
2014-02-11 |
2020-09-25 |
科罗拉多州立大学董事会(法人团体) |
Crispr支持的多路基因组工程化
|
SG11201606819QA
(en)
|
2014-02-18 |
2016-09-29 |
Univ Duke |
Compositions for the inactivation of virus replication and methods of making and using the same
|
AU2015222944A1
(en)
|
2014-02-27 |
2016-09-08 |
Massachusetts Institute Of Technology |
T cell balance gene expression, compositions of matters and methods of use thereof
|
CA2940217C
(en)
|
2014-02-27 |
2023-06-13 |
Monsanto Technology Llc |
Compositions and methods for site directed genomic modification
|
US11028388B2
(en)
|
2014-03-05 |
2021-06-08 |
Editas Medicine, Inc. |
CRISPR/Cas-related methods and compositions for treating Usher syndrome and retinitis pigmentosa
|
CN111500570A
(zh)
|
2014-03-05 |
2020-08-07 |
国立大学法人神户大学 |
特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体
|
US11339437B2
(en)
|
2014-03-10 |
2022-05-24 |
Editas Medicine, Inc. |
Compositions and methods for treating CEP290-associated disease
|
ES2745769T3
(es)
|
2014-03-10 |
2020-03-03 |
Editas Medicine Inc |
Procedimientos y composiciones relacionados con CRISPR/CAS para tratar la amaurosis congénita de Leber 10 (LCA10)
|
US11141493B2
(en)
|
2014-03-10 |
2021-10-12 |
Editas Medicine, Inc. |
Compositions and methods for treating CEP290-associated disease
|
US11242525B2
(en)
|
2014-03-26 |
2022-02-08 |
Editas Medicine, Inc. |
CRISPR/CAS-related methods and compositions for treating sickle cell disease
|
JP6815986B2
(ja)
|
2014-03-26 |
2021-01-20 |
ユニバーシティ オブ メリーランド, カレッジ パーク |
大型家畜の接合体における標的化ゲノム編集
|
WO2015153789A1
(en)
*
|
2014-04-01 |
2015-10-08 |
Editas Medicine, Inc. |
Crispr/cas-related methods and compositions for treating herpes simplex virus type 1 (hsv-1)
|
KR102596508B1
(ko)
|
2014-04-10 |
2023-10-30 |
10엑스 제노믹스, 인크. |
시약을 캡슐화 및 구획화하기 위한 유체 디바이스, 시스템, 및 방법, 및 이의 응용
|
ES2744186T3
(es)
|
2014-04-25 |
2020-02-24 |
Childrens Medical Center |
Composiciones y métodos para tratar las hemoglobinopatías
|
CN106574256A
(zh)
|
2014-05-30 |
2017-04-19 |
斯坦福大学托管董事会 |
用于潜伏病毒感染的递送治疗的组合物和方法
|
WO2015192020A1
(en)
|
2014-06-13 |
2015-12-17 |
Children's Medical Center Corporation |
Products and methods to isolate mitochondria
|
IL286474B2
(en)
|
2014-06-23 |
2023-11-01 |
Massachusetts Gen Hospital |
Genome-wide random identification of DSBS assessed by sequencing (guide-sequence)
|
WO2015200555A2
(en)
*
|
2014-06-25 |
2015-12-30 |
Caribou Biosciences, Inc. |
Rna modification to engineer cas9 activity
|
KR20230070325A
(ko)
|
2014-06-26 |
2023-05-22 |
10엑스 제노믹스, 인크. |
개별 세포 또는 세포 개체군으로부터 핵산을 분석하는 방법
|
MX2017000422A
(es)
|
2014-07-11 |
2017-05-01 |
Du Pont |
Composiciones y metodos para producir plantas resistentes al herbicida glifosato.
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
CN104195177B
(zh)
*
|
2014-08-05 |
2017-06-09 |
南京大学 |
一种显著提高鱼类基因组编辑效率的方法
|
EP3686279B1
(de)
|
2014-08-17 |
2023-01-04 |
The Broad Institute, Inc. |
Genombearbeitung mit cas9-nickasen
|
EP3183367B1
(de)
|
2014-08-19 |
2019-06-26 |
Pacific Biosciences Of California, Inc. |
Zusammensetzungen und verfahren zur anreicherung von nukleinsäuren
|
NZ728437A
(en)
|
2014-08-27 |
2018-02-23 |
Caribou Biosciences Inc |
Methods for increasing cas9-mediated engineering efficiency
|
WO2016036754A1
(en)
|
2014-09-02 |
2016-03-10 |
The Regents Of The University Of California |
Methods and compositions for rna-directed target dna modification
|
EP3191595B1
(de)
|
2014-09-12 |
2019-12-25 |
E. I. du Pont de Nemours and Company |
Erzeugung von stellen zur stellenspezifischen integration für komplexe trait-loci in mais und sojabohnen sowie verfahren zur verwendung
|
WO2016049251A1
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling mutations in leukocytes
|
WO2016049163A2
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Use and production of chd8+/- transgenic animals with behavioral phenotypes characteristic of autism spectrum disorder
|
WO2016049024A2
(en)
|
2014-09-24 |
2016-03-31 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling competition of multiple cancer mutations in vivo
|
WO2016049258A2
(en)
|
2014-09-25 |
2016-03-31 |
The Broad Institute Inc. |
Functional screening with optimized functional crispr-cas systems
|
US10040048B1
(en)
|
2014-09-25 |
2018-08-07 |
Synthego Corporation |
Automated modular system and method for production of biopolymers
|
US20170247762A1
(en)
|
2014-10-27 |
2017-08-31 |
The Board Institute Inc. |
Compositions, methods and use of synthetic lethal screening
|
US9975122B2
(en)
|
2014-11-05 |
2018-05-22 |
10X Genomics, Inc. |
Instrument systems for integrated sample processing
|
WO2016073990A2
(en)
|
2014-11-07 |
2016-05-12 |
Editas Medicine, Inc. |
Methods for improving crispr/cas-mediated genome-editing
|
WO2016077123A1
(en)
*
|
2014-11-10 |
2016-05-19 |
Moderna Therapeutics, Inc. |
Multiparametric nucleic acid optimization
|
EP3626832A3
(de)
|
2014-11-25 |
2020-05-13 |
The Brigham and Women's Hospital, Inc. |
Verfahren zur identifizierung und behandlung einer person mit einer prädisposition für eine kardiometabolische krankheit oder eine davon betroffene person
|
KR101833433B1
(ko)
*
|
2014-11-25 |
2018-02-28 |
한국생명공학연구원 |
돼지 t 세포 및 b 세포 면역결핍 세포주 생산 및 그의 제조 방법
|
EP3224362A4
(de)
|
2014-11-26 |
2018-06-06 |
The Regents of The University of California |
Therapeutische zusammensetzungen mit transkriptionsfaktoren sowie verfahren zur herstellung und verwendung davon
|
GB201421096D0
(en)
|
2014-11-27 |
2015-01-14 |
Imp Innovations Ltd |
Genome editing methods
|
WO2016089866A1
(en)
*
|
2014-12-01 |
2016-06-09 |
President And Fellows Of Harvard College |
Rna-guided systems for in vivo gene editing
|
AU2015355546B2
(en)
|
2014-12-03 |
2021-10-14 |
Agilent Technologies, Inc. |
Guide RNA with chemical modifications
|
CA2969847A1
(en)
|
2014-12-10 |
2016-06-16 |
Regents Of The University Of Minnesota |
Genetically modified cells, tissues, and organs for treating disease
|
WO2016094874A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Escorted and functionalized guides for crispr-cas systems
|
WO2016094880A1
(en)
|
2014-12-12 |
2016-06-16 |
The Broad Institute Inc. |
Delivery, use and therapeutic applications of crispr systems and compositions for genome editing as to hematopoietic stem cells (hscs)
|
EP3230452A1
(de)
|
2014-12-12 |
2017-10-18 |
The Broad Institute Inc. |
Totführungen für crispr-transkriptionsfaktoren
|
EP3230451B1
(de)
|
2014-12-12 |
2021-04-07 |
The Broad Institute, Inc. |
Geschützte guide-rnas (pgrnas)
|
EP3234133B1
(de)
*
|
2014-12-18 |
2020-11-11 |
Integrated DNA Technologies, Inc. |
Zusammensetzungen auf crispr-basis und verfahren zur verwendung
|
WO2016100974A1
(en)
|
2014-12-19 |
2016-06-23 |
The Broad Institute Inc. |
Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing
|
WO2016106236A1
(en)
|
2014-12-23 |
2016-06-30 |
The Broad Institute Inc. |
Rna-targeting system
|
EP3702456A1
(de)
|
2014-12-24 |
2020-09-02 |
The Broad Institute, Inc. |
Crispr mit destabilisierungsdomänen oder mit destabilisierungsdomänenassoziierung
|
WO2016108926A1
(en)
|
2014-12-30 |
2016-07-07 |
The Broad Institute Inc. |
Crispr mediated in vivo modeling and genetic screening of tumor growth and metastasis
|
WO2016114972A1
(en)
|
2015-01-12 |
2016-07-21 |
The Regents Of The University Of California |
Heterodimeric cas9 and methods of use thereof
|
WO2016114970A1
(en)
|
2015-01-12 |
2016-07-21 |
10X Genomics, Inc. |
Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
|
KR20170126875A
(ko)
|
2015-01-28 |
2017-11-20 |
파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 |
Crispr 하이브리드 dna/rna 폴리뉴클레오티드 및 사용 방법
|
WO2016123243A1
(en)
|
2015-01-28 |
2016-08-04 |
The Regents Of The University Of California |
Methods and compositions for labeling a single-stranded target nucleic acid
|
US10738305B2
(en)
|
2015-02-23 |
2020-08-11 |
Vertex Pharmaceuticals Incorporated |
Materials and methods for treatment of hemoglobinopathies
|
US10697000B2
(en)
|
2015-02-24 |
2020-06-30 |
10X Genomics, Inc. |
Partition processing methods and systems
|
EP3262193A2
(de)
|
2015-02-26 |
2018-01-03 |
The Broad Institute Inc. |
T-zellen-balance-genexpression, materialzusammensetzungen und verfahren zur verwendung davon
|
EP3265560B1
(de)
|
2015-03-02 |
2021-12-08 |
Sinai Health System |
Homologe rekombinationsfaktoren
|
WO2016141224A1
(en)
|
2015-03-03 |
2016-09-09 |
The General Hospital Corporation |
Engineered crispr-cas9 nucleases with altered pam specificity
|
EP3274454B1
(de)
*
|
2015-03-25 |
2021-08-25 |
Editas Medicine, Inc. |
Crispr-/cas-verwandte verfahren, zusammensetzungen und komponenten
|
US10450576B2
(en)
|
2015-03-27 |
2019-10-22 |
E I Du Pont De Nemours And Company |
Soybean U6 small nuclear RNA gene promoters and their use in constitutive expression of small RNA genes in plants
|
KR102648489B1
(ko)
|
2015-04-06 |
2024-03-15 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
Crispr/cas-매개 유전자 조절을 위한 화학적으로 변형된 가이드 rna
|
GB201506509D0
(en)
|
2015-04-16 |
2015-06-03 |
Univ Wageningen |
Nuclease-mediated genome editing
|
SG11201708653RA
(en)
|
2015-04-24 |
2017-11-29 |
Editas Medicine Inc |
Evaluation of cas9 molecule/guide rna molecule complexes
|
WO2016182893A1
(en)
|
2015-05-08 |
2016-11-17 |
Teh Broad Institute Inc. |
Functional genomics using crispr-cas systems for saturating mutagenesis of non-coding elements, compositions, methods, libraries and applications thereof
|
JP7288302B2
(ja)
|
2015-05-08 |
2023-06-07 |
ザ チルドレンズ メディカル センター コーポレーション |
胎児型ヘモグロビン再誘導のための、bcl11aエンハンサー機能性領域を標的とする方法
|
EP3294896A1
(de)
|
2015-05-11 |
2018-03-21 |
Editas Medicine, Inc. |
Optimierte crispr/cas9-systeme und verfahren für die geneditierung in stammzellen
|
US10117911B2
(en)
|
2015-05-29 |
2018-11-06 |
Agenovir Corporation |
Compositions and methods to treat herpes simplex virus infections
|
WO2016196655A1
(en)
|
2015-06-03 |
2016-12-08 |
The Regents Of The University Of California |
Cas9 variants and methods of use thereof
|
EP3303585A4
(de)
|
2015-06-03 |
2018-10-31 |
Board of Regents of the University of Nebraska |
Dna-editierung mit verwendung von einzelstrang-dna
|
WO2016193945A2
(en)
|
2015-06-05 |
2016-12-08 |
Novartis Ag |
Methods and compositions for diagnosing, treating, and monitoring treatment of shank3 deficiency associated disorders
|
CN116334142A
(zh)
|
2015-06-09 |
2023-06-27 |
爱迪塔斯医药公司 |
用于改善移植的crispr/cas相关方法和组合物
|
US20160362667A1
(en)
*
|
2015-06-10 |
2016-12-15 |
Caribou Biosciences, Inc. |
CRISPR-Cas Compositions and Methods
|
WO2016205728A1
(en)
|
2015-06-17 |
2016-12-22 |
Massachusetts Institute Of Technology |
Crispr mediated recording of cellular events
|
AU2016278982A1
(en)
|
2015-06-17 |
2018-01-18 |
The Uab Research Foundation |
CRISPR/Cas9 complex for genomic editing
|
WO2016205680A1
(en)
|
2015-06-17 |
2016-12-22 |
The Uab Research Foundation |
Crispr/cas9 complex for introducing a functional polypeptide into cells of blood cell lineage
|
TWI813532B
(zh)
|
2015-06-18 |
2023-09-01 |
美商博得學院股份有限公司 |
降低脱靶效應的crispr酶突變
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
WO2016205745A2
(en)
*
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Cell sorting
|
EP4159856A1
(de)
|
2015-06-18 |
2023-04-05 |
The Broad Institute, Inc. |
Neuartige crispr-enzyme und systeme
|
US10648020B2
(en)
|
2015-06-18 |
2020-05-12 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
EP3436575A1
(de)
|
2015-06-18 |
2019-02-06 |
The Broad Institute Inc. |
Neuartige crispr-enzyme und -systeme
|
WO2017004279A2
(en)
*
|
2015-06-29 |
2017-01-05 |
Massachusetts Institute Of Technology |
Compositions comprising nucleic acids and methods of using the same
|
WO2017004261A1
(en)
|
2015-06-29 |
2017-01-05 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and modified single crispr rna and uses thereof
|
CN108472314A
(zh)
|
2015-07-31 |
2018-08-31 |
明尼苏达大学董事会 |
修饰的细胞和治疗方法
|
US9580727B1
(en)
|
2015-08-07 |
2017-02-28 |
Caribou Biosciences, Inc. |
Compositions and methods of engineered CRISPR-Cas9 systems using split-nexus Cas9-associated polynucleotides
|
WO2017031370A1
(en)
|
2015-08-18 |
2017-02-23 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
CA2996001A1
(en)
*
|
2015-08-25 |
2017-03-02 |
Duke University |
Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases
|
EP4036236A1
(de)
|
2015-08-28 |
2022-08-03 |
The General Hospital Corporation |
Manipulierte crispr-cas9-nukleasen
|
US9926546B2
(en)
|
2015-08-28 |
2018-03-27 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
US9512446B1
(en)
|
2015-08-28 |
2016-12-06 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
US10526590B2
(en)
*
|
2015-08-31 |
2020-01-07 |
Agilent Technologies, Inc. |
Compounds and methods for CRISPR/Cas-based genome editing by homologous recombination
|
ES2938623T3
(es)
|
2015-09-09 |
2023-04-13 |
Univ Kobe Nat Univ Corp |
Método para convertir una secuencia del genoma de una bacteria gram-positiva mediante una conversión específica de una base de ácido nucleico de una secuencia de ADN seleccionada como diana y el complejo molecular utilizado en el mismo
|
AU2016319110B2
(en)
|
2015-09-11 |
2022-01-27 |
The General Hospital Corporation |
Full interrogation of nuclease DSBs and sequencing (FIND-seq)
|
EP3350203A4
(de)
*
|
2015-09-17 |
2019-06-26 |
The Regents of The University of California |
Polypeptide der variante cas9 mit internen insertionen
|
CA3002647A1
(en)
*
|
2015-09-21 |
2017-03-30 |
Arcturus Therapeutics, Inc. |
Allele selective gene editing and uses thereof
|
AU2016326711B2
(en)
|
2015-09-24 |
2022-11-03 |
Editas Medicine, Inc. |
Use of exonucleases to improve CRISPR/Cas-mediated genome editing
|
AU2016331185A1
(en)
|
2015-09-30 |
2018-04-26 |
The General Hospital Corporation |
Comprehensive in vitro reporting of cleavage events by sequencing (CIRCLE-seq)
|
WO2017069958A2
(en)
|
2015-10-09 |
2017-04-27 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
WO2017066497A2
(en)
|
2015-10-13 |
2017-04-20 |
Duke University |
Genome engineering with type i crispr systems in eukaryotic cells
|
EP3365441A1
(de)
|
2015-10-22 |
2018-08-29 |
The Broad Institute Inc. |
Crispr-enzyme des typs vi-b und systeme
|
US9677090B2
(en)
|
2015-10-23 |
2017-06-13 |
Caribou Biosciences, Inc. |
Engineered nucleic-acid targeting nucleic acids
|
JP7067793B2
(ja)
|
2015-10-23 |
2022-05-16 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
核酸塩基編集因子およびその使用
|
WO2017074788A1
(en)
|
2015-10-27 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for targeting cancer-specific sequence variations
|
WO2017075478A2
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
|
WO2017075294A1
(en)
|
2015-10-28 |
2017-05-04 |
The Board Institute Inc. |
Assays for massively combinatorial perturbation profiling and cellular circuit reconstruction
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
WO2017075265A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute, Inc. |
Multiplex analysis of single cell constituents
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
EP3371329A4
(de)
|
2015-11-03 |
2019-06-19 |
President and Fellows of Harvard College |
Verfahren und vorrichtung zur volumetrischen bildgebung einer dreidimensionalen nukleinsäurehaltigen matrix
|
WO2017083852A1
(en)
|
2015-11-13 |
2017-05-18 |
MOORE, Tara |
Methods for the treatment of corneal dystrophies
|
JP7418957B2
(ja)
|
2015-11-16 |
2024-01-22 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
タイチン系ミオパチー及び他のタイチノパチーの治療のための材料及び方法
|
CA3005878A1
(en)
|
2015-11-19 |
2017-05-26 |
The Brigham And Women's Hospital, Inc. |
Lymphocyte antigen cd5-like (cd5l)-interleukin 12b (p40) heterodimers in immunity
|
US11371094B2
(en)
|
2015-11-19 |
2022-06-28 |
10X Genomics, Inc. |
Systems and methods for nucleic acid processing using degenerate nucleotides
|
CN108350499B
(zh)
*
|
2015-11-19 |
2022-05-13 |
10X基因组学有限公司 |
可转化标记组合物、方法及结合其的过程
|
EP3382019B1
(de)
|
2015-11-27 |
2022-05-04 |
National University Corporation Kobe University |
Verfahren zur umwandlung einer monokotpflanzengenomsequenz, in der eine nukleinsäurebasis in gezielter dna-sequenz spezifisch umgewandelt wird, und darin verwendeter molekularkomplex
|
WO2017095944A1
(en)
|
2015-11-30 |
2017-06-08 |
Flagship Pioneering, Inc. |
Methods and compositions relating to chondrisomes from blood products
|
EP3882357B1
(de)
|
2015-12-04 |
2022-08-10 |
10X Genomics, Inc. |
Verfahren und zusammensetzungen zur nukleinsäureanalyse
|
US9771600B2
(en)
|
2015-12-04 |
2017-09-26 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
US9988624B2
(en)
|
2015-12-07 |
2018-06-05 |
Zymergen Inc. |
Microbial strain improvement by a HTP genomic engineering platform
|
US11208649B2
(en)
|
2015-12-07 |
2021-12-28 |
Zymergen Inc. |
HTP genomic engineering platform
|
CA3007635A1
(en)
|
2015-12-07 |
2017-06-15 |
Zymergen Inc. |
Promoters from corynebacterium glutamicum
|
WO2017106767A1
(en)
*
|
2015-12-18 |
2017-06-22 |
The Scripps Research Institute |
Production of unnatural nucleotides using a crispr/cas9 system
|
WO2017106569A1
(en)
|
2015-12-18 |
2017-06-22 |
The Regents Of The University Of California |
Modified site-directed modifying polypeptides and methods of use thereof
|
BR112018013074A2
(pt)
|
2015-12-30 |
2018-12-11 |
Novartis Ag |
terapias de célula efetora imune com eficácia real-çada
|
EA201891619A1
(ru)
|
2016-01-11 |
2019-02-28 |
Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити |
Химерные белки и способы регулирования экспрессии генов
|
CN108463229B
(zh)
|
2016-01-11 |
2023-10-17 |
斯坦福大学托管董事会 |
嵌合蛋白和免疫治疗方法
|
US11845933B2
(en)
*
|
2016-02-03 |
2023-12-19 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide RNA and its applications
|
US10876129B2
(en)
|
2016-02-12 |
2020-12-29 |
Ceres, Inc. |
Methods and materials for high throughput testing of mutagenized allele combinations
|
WO2017143071A1
(en)
|
2016-02-18 |
2017-08-24 |
The Regents Of The University Of California |
Methods and compositions for gene editing in stem cells
|
US20190144942A1
(en)
|
2016-02-22 |
2019-05-16 |
Massachusetts Institute Of Technology |
Methods for identifying and modulating immune phenotypes
|
WO2017147555A1
(en)
*
|
2016-02-26 |
2017-08-31 |
Lanzatech New Zealand Limited |
Crispr/cas systems for c-1 fixing bacteria
|
EP3429567B1
(de)
|
2016-03-16 |
2024-01-10 |
The J. David Gladstone Institutes |
Verfahren und zusammensetzungen zur behandlung von fettleibigkeit und/oder diabetes und zur identifizierung von behandlungskandidaten
|
EP3219799A1
(de)
|
2016-03-17 |
2017-09-20 |
IMBA-Institut für Molekulare Biotechnologie GmbH |
Bedingte crispr-sgrna-expression
|
WO2017161325A1
(en)
|
2016-03-17 |
2017-09-21 |
Massachusetts Institute Of Technology |
Methods for identifying and modulating co-occurant cellular phenotypes
|
CA3018729A1
(en)
|
2016-03-23 |
2017-09-28 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
WO2017165859A1
(en)
*
|
2016-03-24 |
2017-09-28 |
Research Institute At Nationwide Children's Hospital |
Modified viral capsid proteins
|
EP3433363A1
(de)
|
2016-03-25 |
2019-01-30 |
Editas Medicine, Inc. |
Genombearbeitungssysteme mit reparaturmodulierenden enzymmolekülen und verfahren zu deren verwendung
|
WO2017165862A1
(en)
|
2016-03-25 |
2017-09-28 |
Editas Medicine, Inc. |
Systems and methods for treating alpha 1-antitrypsin (a1at) deficiency
|
US11236313B2
(en)
|
2016-04-13 |
2022-02-01 |
Editas Medicine, Inc. |
Cas9 fusion molecules, gene editing systems, and methods of use thereof
|
SG11201808920RA
(en)
*
|
2016-04-14 |
2018-11-29 |
Boco Silicon Valley Inc |
Genome editing of human neural stem cells using nucleases
|
EP3445853A1
(de)
|
2016-04-19 |
2019-02-27 |
The Broad Institute, Inc. |
Cpf1-komplexe mit reduzierter indelaktivität
|
SG11201810179RA
(en)
*
|
2016-04-19 |
2018-12-28 |
Broad Inst Inc |
Novel crispr enzymes and systems
|
CA3022290A1
(en)
|
2016-04-25 |
2017-11-02 |
President And Fellows Of Harvard College |
Hybridization chain reaction methods for in situ molecular detection
|
WO2017197338A1
(en)
|
2016-05-13 |
2017-11-16 |
10X Genomics, Inc. |
Microfluidic systems and methods of use
|
US10767175B2
(en)
*
|
2016-06-08 |
2020-09-08 |
Agilent Technologies, Inc. |
High specificity genome editing using chemically modified guide RNAs
|
AU2017283713B2
(en)
|
2016-06-17 |
2021-04-08 |
Massachusetts Institute Of Technology |
Type VI CRISPR orthologs and systems
|
US10017760B2
(en)
|
2016-06-24 |
2018-07-10 |
Inscripta, Inc. |
Methods for generating barcoded combinatorial libraries
|
EP3474849A4
(de)
|
2016-06-27 |
2020-07-29 |
The Broad Institute, Inc. |
Zusammensetzungen und verfahren zur erkennung und behandlung von tumoren
|
WO2018005589A1
(en)
|
2016-06-28 |
2018-01-04 |
Cellectis |
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
|
US10544390B2
(en)
|
2016-06-30 |
2020-01-28 |
Zymergen Inc. |
Methods for generating a bacterial hemoglobin library and uses thereof
|
JP2019519241A
(ja)
|
2016-06-30 |
2019-07-11 |
ザイマージェン インコーポレイテッド |
グルコース透過酵素ライブラリーを生成するための方法およびその使用
|
CA3030783A1
(en)
|
2016-07-13 |
2018-01-18 |
Vertex Pharmaceuticals Incorporated |
Methods, compositions and kits for increasing genome editing efficiency
|
CA3032822A1
(en)
|
2016-08-02 |
2018-02-08 |
Editas Medicine, Inc. |
Compositions and methods for treating cep290 associated disease
|
JP7231935B2
(ja)
|
2016-08-03 |
2023-03-08 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
アデノシン核酸塩基編集因子およびそれらの使用
|
US11078481B1
(en)
|
2016-08-03 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for screening for cancer targets
|
AU2017308889B2
(en)
|
2016-08-09 |
2023-11-09 |
President And Fellows Of Harvard College |
Programmable Cas9-recombinase fusion proteins and uses thereof
|
US20210166783A1
(en)
|
2016-08-17 |
2021-06-03 |
The Broad Institute, Inc. |
Methods for identifying class 2 crispr-cas systems
|
EP3500671A4
(de)
|
2016-08-17 |
2020-07-29 |
The Broad Institute, Inc. |
Neuartige crispr-enzyme und -systeme
|
WO2018035364A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute Inc. |
Product and methods useful for modulating and evaluating immune responses
|
US11810649B2
(en)
|
2016-08-17 |
2023-11-07 |
The Broad Institute, Inc. |
Methods for identifying novel gene editing elements
|
KR102594051B1
(ko)
|
2016-08-20 |
2023-10-26 |
아벨리노 랩 유에스에이, 인크. |
단일 가이드 RNA, CRISPR/Cas9 시스템, 및 이의 사용방법
|
WO2020225754A1
(en)
|
2019-05-06 |
2020-11-12 |
Mcmullen Tara |
Crispr gene editing for autosomal dominant diseases
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
US11078483B1
(en)
|
2016-09-02 |
2021-08-03 |
KSQ Therapeutics, Inc. |
Methods for measuring and improving CRISPR reagent function
|
WO2018049025A2
(en)
|
2016-09-07 |
2018-03-15 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses
|
US11306305B2
(en)
|
2016-09-23 |
2022-04-19 |
Board Of Trustees Of Southern Illinois University |
Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions
|
US20190225974A1
(en)
|
2016-09-23 |
2019-07-25 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome optimization in plants
|
WO2018064371A1
(en)
|
2016-09-30 |
2018-04-05 |
The Regents Of The University Of California |
Rna-guided nucleic acid modifying enzymes and methods of use thereof
|
US10669539B2
(en)
|
2016-10-06 |
2020-06-02 |
Pioneer Biolabs, Llc |
Methods and compositions for generating CRISPR guide RNA libraries
|
US11242542B2
(en)
|
2016-10-07 |
2022-02-08 |
Integrated Dna Technologies, Inc. |
S. pyogenes Cas9 mutant genes and polypeptides encoded by same
|
EP3523427A4
(de)
|
2016-10-07 |
2020-09-02 |
Integrated DNA Technologies, Inc. |
S.-pyogenes-cas9-mutantengene und dadurch codierte polypeptide
|
US20200016202A1
(en)
|
2016-10-07 |
2020-01-16 |
The Brigham And Women's Hospital, Inc. |
Modulation of novel immune checkpoint targets
|
KR20240007715A
(ko)
|
2016-10-14 |
2024-01-16 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵염기 에디터의 aav 전달
|
GB201617559D0
(en)
|
2016-10-17 |
2016-11-30 |
University Court Of The University Of Edinburgh The |
Swine comprising modified cd163 and associated methods
|
CN110520530A
(zh)
|
2016-10-18 |
2019-11-29 |
明尼苏达大学董事会 |
肿瘤浸润性淋巴细胞和治疗方法
|
WO2018083606A1
(en)
|
2016-11-01 |
2018-05-11 |
Novartis Ag |
Methods and compositions for enhancing gene editing
|
AU2017355507B2
(en)
|
2016-11-04 |
2023-09-21 |
Flagship Pioneering Innovations V. Inc. |
Novel plant cells, plants, and seeds
|
EP4321617A3
(de)
|
2016-11-22 |
2024-04-24 |
Integrated DNA Technologies Inc. |
Crispr/cpf1-systeme und -verfahren
|
US9816093B1
(en)
|
2016-12-06 |
2017-11-14 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
US11293022B2
(en)
|
2016-12-12 |
2022-04-05 |
Integrated Dna Technologies, Inc. |
Genome editing enhancement
|
AU2017378427A1
(en)
|
2016-12-14 |
2019-06-20 |
Ligandal, Inc. |
Methods and compositions for nucleic acid and protein payload delivery
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
WO2018140899A1
(en)
|
2017-01-28 |
2018-08-02 |
Inari Agriculture, Inc. |
Novel plant cells, plants, and seeds
|
EP4310183A3
(de)
|
2017-01-30 |
2024-02-21 |
10X Genomics, Inc. |
Verfahren und systeme zur tröpfchenbasierten einzelzellenbarcodierung
|
TW201839136A
(zh)
|
2017-02-06 |
2018-11-01 |
瑞士商諾華公司 |
治療血色素異常症之組合物及方法
|
US10995333B2
(en)
|
2017-02-06 |
2021-05-04 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation
|
CN110312797A
(zh)
|
2017-02-10 |
2019-10-08 |
齐默尔根公司 |
组装和编辑用于多个宿主的多个dna构建体的模块化通用质粒设计策略
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
EP3592777A1
(de)
|
2017-03-10 |
2020-01-15 |
President and Fellows of Harvard College |
Cytosin-zu-guanin-baseneditor
|
EP3596217A1
(de)
|
2017-03-14 |
2020-01-22 |
Editas Medicine, Inc. |
Systeme und verfahren zur behandlung von hämoglobinopathien
|
CN110959039A
(zh)
|
2017-03-15 |
2020-04-03 |
博德研究所 |
新型cas13b直向同源物crispr酶和系统
|
US20200115753A1
(en)
|
2017-03-17 |
2020-04-16 |
Massachusetts Institute Of Technology |
Methods for identifying and modulating co-occurant cellular phenotypes
|
KR20190130613A
(ko)
|
2017-03-23 |
2019-11-22 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
EP3606518A4
(de)
|
2017-04-01 |
2021-04-07 |
The Broad Institute, Inc. |
Verfahren und zusammensetzungen zur detektion und zur modulation einer immuntherapieresistenzgensignatur in krebs
|
US20210115407A1
(en)
|
2017-04-12 |
2021-04-22 |
The Broad Institute, Inc. |
Respiratory and sweat gland ionocytes
|
CA3059757A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Novel type vi crispr orthologs and systems
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
WO2018191750A2
(en)
|
2017-04-14 |
2018-10-18 |
The Broad Institute Inc. |
Novel delivery of large payloads
|
EP3612629A1
(de)
|
2017-04-18 |
2020-02-26 |
The Broad Institute, Inc. |
Zusammensetzungen zur erkennung von sekretion und verwendungsverfahren
|
EP3612232A1
(de)
|
2017-04-21 |
2020-02-26 |
The Broad Institute, Inc. |
Gezielte abgabe an beta-zellen
|
AU2018254619B2
(en)
|
2017-04-21 |
2022-07-21 |
The General Hospital Corporation |
Variants of Cpf1 (CAS12a) with altered PAM specificity
|
US11499151B2
(en)
|
2017-04-28 |
2022-11-15 |
Editas Medicine, Inc. |
Methods and systems for analyzing guide RNA molecules
|
US11591601B2
(en)
|
2017-05-05 |
2023-02-28 |
The Broad Institute, Inc. |
Methods for identification and modification of lncRNA associated with target genotypes and phenotypes
|
US20210147798A1
(en)
*
|
2017-05-08 |
2021-05-20 |
Toolgen Incorporated |
Artificially Manipulated Immune Cell
|
WO2019103857A1
(en)
|
2017-11-22 |
2019-05-31 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
WO2018209158A2
(en)
|
2017-05-10 |
2018-11-15 |
Editas Medicine, Inc. |
Crispr/rna-guided nuclease systems and methods
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
EP3625343A1
(de)
|
2017-05-18 |
2020-03-25 |
The Broad Institute, Inc. |
Systeme, verfahren und zusammensetzungen zur gezielten nukleinsäureeditierung
|
US11788087B2
(en)
|
2017-05-25 |
2023-10-17 |
The Children's Medical Center Corporation |
BCL11A guide delivery
|
AU2018272067A1
(en)
|
2017-05-25 |
2019-11-28 |
The General Hospital Corporation |
Base editors with improved precision and specificity
|
US10844372B2
(en)
|
2017-05-26 |
2020-11-24 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
CN109526228B
(zh)
|
2017-05-26 |
2022-11-25 |
10X基因组学有限公司 |
转座酶可接近性染色质的单细胞分析
|
EP3409104A1
(de)
|
2017-05-31 |
2018-12-05 |
Vilmorin et Cie |
Tomatenpflanze, die gegen tomatengelbblattkräuselvirus, pulverförmigen mehltau und nematoden beständig ist
|
WO2020249996A1
(en)
|
2019-06-14 |
2020-12-17 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus
|
EP3409106A1
(de)
|
2017-06-01 |
2018-12-05 |
Vilmorin et Cie |
Toleranz in pflanzen von solanum lycopersicum gegenüber dem tobamovirus tomato brown rugose fruit virus (tbrfv)
|
CA3102054A1
(en)
|
2017-06-05 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Genomic safe harbors for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies
|
CN110719956A
(zh)
|
2017-06-06 |
2020-01-21 |
齐默尔根公司 |
用于改良真菌菌株的高通量基因组工程改造平台
|
JP2020524490A
(ja)
|
2017-06-06 |
2020-08-20 |
ザイマージェン インコーポレイテッド |
Escherichia Coliを改良するためのHTPゲノム操作プラットフォーム
|
JP2020524497A
(ja)
|
2017-06-09 |
2020-08-20 |
エディタス・メディシン,インコーポレイテッド |
操作されたcas9ヌクレアーゼ
|
CN111108208A
(zh)
|
2017-06-13 |
2020-05-05 |
旗舰先锋创新V股份有限公司 |
包含愈合子的组合物及其用途
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
CN111328290A
(zh)
|
2017-06-26 |
2020-06-23 |
博德研究所 |
用于靶向核酸编辑的基于crispr/cas-腺嘌呤脱氨酶的组合物、系统和方法
|
US20200140896A1
(en)
|
2017-06-30 |
2020-05-07 |
Novartis Ag |
Methods for the treatment of disease with gene editing systems
|
EP3645021A4
(de)
|
2017-06-30 |
2021-04-21 |
Intima Bioscience, Inc. |
Adeno-assoziierte virale vektoren zur gentherapie
|
EP3640333A4
(de)
*
|
2017-07-14 |
2020-12-30 |
Cure Genetics Co., Ltd |
System und verfahren zur geneditierung
|
EP3652312A1
(de)
|
2017-07-14 |
2020-05-20 |
Editas Medicine, Inc. |
Systeme und verfahren zur gezielten integration und genomeditierung und deren detektion unter verwendung von integrierten bindungsstellen
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
AU2018320865B2
(en)
|
2017-08-23 |
2023-09-14 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
|
WO2019139645A2
(en)
|
2017-08-30 |
2019-07-18 |
President And Fellows Of Harvard College |
High efficiency base editors comprising gam
|
WO2019060759A1
(en)
|
2017-09-21 |
2019-03-28 |
Dana-Farber Cancer Institute, Inc. |
ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF PLANT EXTRACTS JUSTICIA
|
US11618896B2
(en)
|
2017-09-21 |
2023-04-04 |
The Broad Institute, Inc. |
Systems, methods, and compositions for targeted nucleic acid editing
|
US11572574B2
(en)
|
2017-09-28 |
2023-02-07 |
Toolgen Incorporated |
Artificial genome manipulation for gene expression regulation
|
EP3690047A4
(de)
*
|
2017-09-28 |
2021-11-03 |
Toolgen Incorporated |
Künstliche genommanipulation zur genexpressionsregulierung
|
EP3692152A4
(de)
|
2017-10-04 |
2021-12-01 |
The Broad Institute, Inc. |
Verfahren und zusammensetzungen zur veränderung der funktion und struktur von chromatinschleifen und/oder -domänen
|
EP3694993A4
(de)
|
2017-10-11 |
2021-10-13 |
The General Hospital Corporation |
Verfahren zur detektion einer ortsspezifischen und unerwünschten genomischen desaminierung, die durch baseneditierungstechnologien induziert wird
|
WO2019079347A1
(en)
|
2017-10-16 |
2019-04-25 |
The Broad Institute, Inc. |
USES OF BASIC EDITORS ADENOSINE
|
WO2019079362A1
(en)
|
2017-10-16 |
2019-04-25 |
Massachusetts Institute Of Technology |
HOST-PATHOGENIC INTERACTION OF MYCOBACTERIUM TUBERCULOSIS
|
CN111479916A
(zh)
|
2017-10-20 |
2020-07-31 |
弗莱德哈钦森癌症研究中心 |
用以产生被遗传修饰来表达所选抗体的b细胞的系统和方法
|
WO2019089803A1
(en)
|
2017-10-31 |
2019-05-09 |
The Broad Institute, Inc. |
Methods and compositions for studying cell evolution
|
EP3704245A1
(de)
|
2017-11-01 |
2020-09-09 |
Novartis AG |
Synthetische rnas und verfahren zur verwendung
|
WO2019084664A1
(en)
*
|
2017-11-02 |
2019-05-09 |
The Governors Of The University Of Alberta |
Chemically-modified guide rnas to improve crispr-cas protein specificity
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
EP3625361A1
(de)
|
2017-11-15 |
2020-03-25 |
10X Genomics, Inc. |
Funktionalisierte gelperlen
|
US20210180059A1
(en)
*
|
2017-11-16 |
2021-06-17 |
Astrazeneca Ab |
Compositions and methods for improving the efficacy of cas9-based knock-in strategies
|
KR20200100060A
(ko)
|
2017-11-17 |
2020-08-25 |
이오반스 바이오테라퓨틱스, 인크. |
미세 바늘 흡인물 및 소형 생검물로부터의 til 확장
|
US10829815B2
(en)
|
2017-11-17 |
2020-11-10 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
US11332736B2
(en)
|
2017-12-07 |
2022-05-17 |
The Broad Institute, Inc. |
Methods and compositions for multiplexing single cell and single nuclei sequencing
|
WO2019126037A1
(en)
|
2017-12-19 |
2019-06-27 |
City Of Hope |
Modified tracrrnas grnas, and uses thereof
|
RU2652899C1
(ru)
*
|
2017-12-28 |
2018-05-03 |
Федеральное бюджетное учреждение науки "Центральный научно-исследовательский институт эпидемиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ЦНИИ Эпидемиологии Роспотребнадзора) |
РНК-проводники для подавления репликации вируса гепатита B и для элиминации вируса гепатита B из клетки-хозяина
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
US20200362366A1
(en)
|
2018-01-12 |
2020-11-19 |
Basf Se |
Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a
|
CN111770921B
(zh)
|
2018-01-17 |
2024-03-22 |
沃泰克斯药物股份有限公司 |
用于提高基因组编辑效率的喹喔啉酮化合物,组合物,方法和试剂盒
|
BR112020014140A2
(pt)
|
2018-01-17 |
2020-12-01 |
Vertex Pharmaceuticals Incorporated |
inibidores de dna-pk
|
KR20200110685A
(ko)
|
2018-01-17 |
2020-09-24 |
버텍스 파마슈티칼스 인코포레이티드 |
Dna-pk 억제제
|
WO2019147743A1
(en)
|
2018-01-26 |
2019-08-01 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide rna and its applications
|
US11926835B1
(en)
|
2018-01-29 |
2024-03-12 |
Inari Agriculture Technology, Inc. |
Methods for efficient tomato genome editing
|
WO2019150196A1
(en)
|
2018-02-05 |
2019-08-08 |
Crispr Therapeutics Ag |
Materials and methods for treatment of hemoglobinopathies
|
WO2019150203A1
(en)
|
2018-02-05 |
2019-08-08 |
Crispr Therapeutics Ag |
Materials and methods for treatment of hemoglobinopathies
|
WO2019157326A1
(en)
|
2018-02-08 |
2019-08-15 |
Zymergen Inc. |
Genome editing using crispr in corynebacterium
|
CN112005115A
(zh)
|
2018-02-12 |
2020-11-27 |
10X基因组学有限公司 |
表征来自单个细胞或细胞群体的多种分析物的方法
|
PL235163B1
(pl)
*
|
2018-04-05 |
2020-06-01 |
Inst Hodowli I Aklimatyzacji Roslin Panstwowy Inst Badawczy |
Sekwencja nukleotydowa syntetycznego genu Cas9, kaseta kierująca sgRNA do edytowania genomu roślinnego i wydajny system do ukierunkowanej mutagenezy wybranego regionu genomu roślinnego
|
CN112262218A
(zh)
|
2018-04-06 |
2021-01-22 |
10X基因组学有限公司 |
用于单细胞处理中的质量控制的系统和方法
|
CA3096274A1
(en)
|
2018-04-06 |
2019-10-10 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
CN112313241A
(zh)
|
2018-04-17 |
2021-02-02 |
总医院公司 |
核酸结合、修饰、和切割试剂的底物偏好和位点的灵敏体外试验
|
JP2021521788A
(ja)
|
2018-04-19 |
2021-08-30 |
ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア |
ゲノム編集のための組成物および方法
|
WO2019204585A1
(en)
|
2018-04-19 |
2019-10-24 |
Massachusetts Institute Of Technology |
Single-stranded break detection in double-stranded dna
|
DK3560330T3
(da)
|
2018-04-24 |
2022-07-11 |
Kws Saat Se & Co Kgaa |
Planter med forbedret fordøjelighed og markørhaplotyper
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
CN112334510A
(zh)
|
2018-04-27 |
2021-02-05 |
基因编辑有限公司 |
阳离子聚合物和用于生物分子递送的用途
|
US20210147831A1
(en)
|
2018-04-27 |
2021-05-20 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
CA3098303A1
(en)
|
2018-04-27 |
2019-10-31 |
Iovance Biotherapeutics, Inc. |
Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
EP3788144A4
(de)
*
|
2018-05-01 |
2022-05-11 |
The Children's Medical Center Corporation |
Abgabe und editing von erweitertem bcl11a-rnp/crispr unter verwendung einer 3xnls-cas9
|
US20210386829A1
(en)
|
2018-05-04 |
2021-12-16 |
The Broad Institute, Inc. |
Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
|
WO2019222545A1
(en)
|
2018-05-16 |
2019-11-21 |
Synthego Corporation |
Methods and systems for guide rna design and use
|
CN108707628B
(zh)
*
|
2018-05-28 |
2021-11-23 |
上海海洋大学 |
斑马鱼notch2基因突变体的制备方法
|
WO2019232542A2
(en)
|
2018-06-01 |
2019-12-05 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
US11866719B1
(en)
|
2018-06-04 |
2024-01-09 |
Inari Agriculture Technology, Inc. |
Heterologous integration of regulatory elements to alter gene expression in wheat cells and wheat plants
|
US20210222125A1
(en)
|
2018-06-07 |
2021-07-22 |
The Brigham And Women`S Hospital, Inc. |
Methods for generating hematopoietic stem cells
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
EP3814527B1
(de)
|
2018-06-26 |
2023-02-22 |
Massachusetts Institute of Technology |
Verfahren, systeme und diagnostika auf der basis von crispr-effektorsystemen
|
JP2021528975A
(ja)
|
2018-06-26 |
2021-10-28 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
Crispr/cas及びトランスポザーゼを利用した増幅用の組成物、システム、及び方法
|
US11629179B2
(en)
|
2018-06-29 |
2023-04-18 |
Stichting Het Nederlands Kanker Instituut—Antoni van Leeuwenhoek Ziekenhuis |
TWEAK-receptor agonists for use in combination with immunotherapy of a cancer
|
JP2021530212A
(ja)
|
2018-07-13 |
2021-11-11 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California |
レトロトランスポゾンベースの送達媒体及びその使用方法
|
US20200032335A1
(en)
|
2018-07-27 |
2020-01-30 |
10X Genomics, Inc. |
Systems and methods for metabolome analysis
|
CA3111432A1
(en)
|
2018-07-31 |
2020-02-06 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
WO2020028729A1
(en)
|
2018-08-01 |
2020-02-06 |
Mammoth Biosciences, Inc. |
Programmable nuclease compositions and methods of use thereof
|
CN113286884A
(zh)
|
2018-08-07 |
2021-08-20 |
博德研究所 |
新型cas12b酶和系统
|
EP3607819A1
(de)
|
2018-08-10 |
2020-02-12 |
Vilmorin et Cie |
Resistenz gegen xanthomonas campestris pv. campestris (xcc) in blumenkohl
|
CA3107002A1
(en)
|
2018-08-15 |
2020-04-30 |
Zymergen Inc. |
Applications of crispri in high throughput metabolic engineering
|
WO2020041380A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
WO2020041387A1
(en)
|
2018-08-20 |
2020-02-27 |
The Brigham And Women's Hospital, Inc. |
Degradation domain modifications for spatio-temporal control of rna-guided nucleases
|
AU2019326408A1
(en)
|
2018-08-23 |
2021-03-11 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
EP3841203A4
(de)
*
|
2018-08-23 |
2022-11-02 |
The Broad Institute Inc. |
Cas9-varianten mit nicht-kanonischen pam-spezifitäten und deren verwendungen
|
US11459551B1
(en)
|
2018-08-31 |
2022-10-04 |
Inari Agriculture Technology, Inc. |
Compositions, systems, and methods for genome editing
|
US20210317479A1
(en)
|
2018-09-06 |
2021-10-14 |
The Broad Institute, Inc. |
Nucleic acid assemblies for use in targeted delivery
|
EP4268831A3
(de)
|
2018-09-12 |
2024-05-22 |
Fred Hutchinson Cancer Center |
Verminderung der cd33-expression zum selektiven schutz von therapeutischen zellen
|
US20220088224A1
(en)
|
2018-09-18 |
2022-03-24 |
Vnv Newco Inc. |
Arc-based capsids and uses thereof
|
WO2020069029A1
(en)
|
2018-09-26 |
2020-04-02 |
Emendobio Inc. |
Novel crispr nucleases
|
US20220411783A1
(en)
|
2018-10-12 |
2022-12-29 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
US20210379057A1
(en)
|
2018-10-16 |
2021-12-09 |
Massachusetts Institute Of Technology |
Nutlin-3a for use in treating a mycobacterium tuberculosis infection
|
EP3870600A1
(de)
|
2018-10-24 |
2021-09-01 |
Obsidian Therapeutics, Inc. |
Er-abstimmbare proteinregulierung
|
EP3870628B1
(de)
|
2018-10-24 |
2024-04-03 |
Genedit Inc. |
Kationisches polymer mit alkylseitenketten und verwendung zur verabreichung von biomolekülen
|
US11407995B1
(en)
|
2018-10-26 |
2022-08-09 |
Inari Agriculture Technology, Inc. |
RNA-guided nucleases and DNA binding proteins
|
US11066663B2
(en)
|
2018-10-31 |
2021-07-20 |
Zymergen Inc. |
Multiplexed deterministic assembly of DNA libraries
|
WO2020089448A1
(en)
*
|
2018-11-01 |
2020-05-07 |
Keygene N.V. |
Dual guide rna for crispr/cas genome editing in plants cells
|
US11434477B1
(en)
|
2018-11-02 |
2022-09-06 |
Inari Agriculture Technology, Inc. |
RNA-guided nucleases and DNA binding proteins
|
SG11202104663PA
(en)
|
2018-11-05 |
2021-06-29 |
Iovance Biotherapeutics Inc |
Treatment of nsclc patients refractory for anti-pd-1 antibody
|
BR112021008573A2
(pt)
|
2018-11-05 |
2021-10-26 |
Iovance Biotherapeutics, Inc. |
Métodos para expandir linfócitos infiltrantes de tumor em uma população terapêutica de linfócitos infiltrantes de tumor, para tratar um sujeito com câncer e de expansão de células t, população terapêutica de linfócitos infiltrantes de tumor, composição de linfócitos infiltrantes de tumor, saco de infusão estéril, preparação criopreservada, e, uso da composição de linfócitos infiltrantes de tumor.
|
CN113272420A
(zh)
|
2018-11-05 |
2021-08-17 |
艾欧凡斯生物治疗公司 |
经改进的肿瘤反应性t细胞的选择
|
MX2021004775A
(es)
|
2018-11-05 |
2021-06-08 |
Iovance Biotherapeutics Inc |
Expansion de linfocitos infiltrantes de tumores (tils) usando inhibidores de la via de proteina cinasa b (akt).
|
EP3876745A2
(de)
|
2018-11-08 |
2021-09-15 |
Triton Algae Innovations, Inc. |
Zusammensetzungen und verfahren zur integration von häm aus algen in essbare produkte
|
US11459607B1
(en)
|
2018-12-10 |
2022-10-04 |
10X Genomics, Inc. |
Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
|
US11166996B2
(en)
|
2018-12-12 |
2021-11-09 |
Flagship Pioneering Innovations V, Inc. |
Anellovirus compositions and methods of use
|
AU2019398351A1
(en)
|
2018-12-14 |
2021-06-03 |
Pioneer Hi-Bred International, Inc. |
Novel CRISPR-Cas systems for genome editing
|
AU2019406778A1
(en)
|
2018-12-17 |
2021-07-22 |
Massachusetts Institute Of Technology |
Crispr-associated transposase systems and methods of use thereof
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
JP2022514023A
(ja)
|
2018-12-19 |
2022-02-09 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
操作されたサイトカイン受容体対を使用して腫瘍浸潤リンパ球を拡大培養する方法及びその使用
|
WO2020142754A2
(en)
|
2019-01-04 |
2020-07-09 |
Mammoth Biosciences, Inc. |
Programmable nuclease improvements and compositions and methods for nucleic acid amplification and detection
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
US11845983B1
(en)
|
2019-01-09 |
2023-12-19 |
10X Genomics, Inc. |
Methods and systems for multiplexing of droplet based assays
|
US20220119871A1
(en)
|
2019-01-28 |
2022-04-21 |
The Broad Institute, Inc. |
In-situ spatial transcriptomics
|
WO2020163396A1
(en)
|
2019-02-04 |
2020-08-13 |
The General Hospital Corporation |
Adenine dna base editor variants with reduced off-target rna editing
|
WO2020163379A1
(en)
|
2019-02-05 |
2020-08-13 |
Emendobio Inc. |
Crispr compositions and methods for promoting gene editing of ribosomal protein s19 (rps19) gene
|
US20220145330A1
(en)
|
2019-02-10 |
2022-05-12 |
The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Glads |
Modified mitochondrion and methods of use thereof
|
US11851683B1
(en)
|
2019-02-12 |
2023-12-26 |
10X Genomics, Inc. |
Methods and systems for selective analysis of cellular samples
|
JP2022522473A
(ja)
|
2019-03-01 |
2022-04-19 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
液性腫瘍からの腫瘍浸潤リンパ球の拡大培養及びその治療的使用
|
CA3130789A1
(en)
|
2019-03-07 |
2020-09-10 |
The Regents Of The University Of California |
Crispr-cas effector polypeptides and methods of use thereof
|
US11053515B2
(en)
|
2019-03-08 |
2021-07-06 |
Zymergen Inc. |
Pooled genome editing in microbes
|
CA3129871A1
(en)
|
2019-03-08 |
2020-09-17 |
Zymergen Inc. |
Iterative genome editing in microbes
|
AU2020235865A1
(en)
|
2019-03-08 |
2021-09-23 |
Obsidian Therapeutics, Inc. |
Human carbonic anhydrase 2 compositions and methods for tunable regulation
|
EP3942040A1
(de)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Verfahren und zusammensetzungen zur editierung von nukleotidsequenzen
|
WO2020206036A1
(en)
|
2019-04-01 |
2020-10-08 |
The Broad Institute, Inc. |
Novel nucleic acid modifier
|
US20220186263A1
(en)
|
2019-04-05 |
2022-06-16 |
Osaka University |
Method for producing knock-in cell
|
CA3137382A1
(en)
|
2019-04-23 |
2020-10-29 |
Genedit Inc. |
Cationic polymer with alkyl side chains
|
EP3969607A1
(de)
|
2019-05-13 |
2022-03-23 |
KWS SAAT SE & Co. KGaA |
Trockenheitstoleranz bei mais
|
US20220249559A1
(en)
|
2019-05-13 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
WO2020236967A1
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Random crispr-cas deletion mutant
|
WO2020236972A2
(en)
|
2019-05-20 |
2020-11-26 |
The Broad Institute, Inc. |
Non-class i multi-component nucleic acid targeting systems
|
AR118995A1
(es)
|
2019-05-25 |
2021-11-17 |
Kws Saat Se & Co Kgaa |
Mejorador de la inducción de haploides
|
AU2020282798A1
(en)
|
2019-05-28 |
2021-12-16 |
Genedit Inc. |
Polymer comprising multiple functionalized sidechains for biomolecule delivery
|
US20220243178A1
(en)
|
2019-05-31 |
2022-08-04 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
WO2020254850A1
(en)
|
2019-06-21 |
2020-12-24 |
Vilmorin & Cie |
Improvement of quality and permanence of green color of peppers at maturity and over-maturity
|
US11041172B2
(en)
|
2019-06-25 |
2021-06-22 |
Inari Agriculture, Inc. |
Homology dependent repair genome editing
|
BR112021026832A2
(pt)
|
2019-07-02 |
2022-05-10 |
Hutchinson Fred Cancer Res |
Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada
|
WO2021019272A1
(en)
|
2019-07-31 |
2021-02-04 |
Vilmorin & Cie |
Tolerance to tolcndv in cucumber
|
EP3772542A1
(de)
|
2019-08-07 |
2021-02-10 |
KWS SAAT SE & Co. KGaA |
Modifzierung der genetischen variation bei nutzpflanzen durch modulation des pachytän-checkpointproteins 2
|
WO2021028359A1
(en)
|
2019-08-09 |
2021-02-18 |
Sangamo Therapeutics France |
Controlled expression of chimeric antigen receptors in t cells
|
US20220298501A1
(en)
|
2019-08-30 |
2022-09-22 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
US11116797B2
(en)
|
2019-09-05 |
2021-09-14 |
Crispr Therapeutics Ag |
Universal donor cells
|
US11104918B2
(en)
*
|
2019-09-05 |
2021-08-31 |
Crispr Therapeutics Ag |
Universal donor cells
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
EP4031660A1
(de)
|
2019-09-20 |
2022-07-27 |
The Broad Institute, Inc. |
Neuartige typ-vi-crispr-enzyme und systeme
|
EP4041894A1
(de)
|
2019-09-23 |
2022-08-17 |
Omega Therapeutics, Inc. |
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULIERUNG DER HEPATOZYTENNUKLEARFAKTOR-4-ALPHA (HNF4a)-GENEXPRESSION
|
WO2021061707A1
(en)
|
2019-09-23 |
2021-04-01 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein b (apob) gene expression
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
WO2021074367A1
(en)
|
2019-10-17 |
2021-04-22 |
KWS SAAT SE & Co. KGaA |
Enhanced disease resistance of crops by downregulation of repressor genes
|
WO2021081378A1
(en)
|
2019-10-25 |
2021-04-29 |
Iovance Biotherapeutics, Inc. |
Gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
GB201916020D0
(en)
|
2019-11-04 |
2019-12-18 |
Univ Of Essex Enterprise Limited |
Crispr-mediated identification of biotinylated proteins and chromatin regions
|
EP4057802A1
(de)
|
2019-11-14 |
2022-09-21 |
Vilmorin & Cie |
Widerstand gegen acidovorax valerianellae in maissalat
|
US20230220341A1
(en)
|
2019-12-11 |
2023-07-13 |
lovance Biotherapeutics, Inc. |
Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
|
CN116234906A
(zh)
|
2020-01-13 |
2023-06-06 |
萨那生物技术股份有限公司 |
血型抗原的修饰
|
CA3165346A1
(en)
|
2020-01-23 |
2021-07-29 |
George Q. Daley |
Stroma-free t cell differentiation from human pluripotent stem cells
|
EP3872190A1
(de)
|
2020-02-26 |
2021-09-01 |
Antibodies-Online GmbH |
Verfahren zur verwendung von cut&run oder cut&tag zur validierung von crispr-cas-targeting
|
CN115768898A
(zh)
|
2020-02-28 |
2023-03-07 |
科沃施种子欧洲股份两合公司 |
用于顽拗型植物的快速基因组修饰的方法
|
BR112022015463A2
(pt)
|
2020-02-28 |
2022-12-13 |
Kws Saat Se & Co Kgaa |
Edição de meristema de inflorescência imatura
|
EP4118207A1
(de)
|
2020-03-11 |
2023-01-18 |
Omega Therapeutics, Inc. |
Zusammensetzungen und verfahren zur modulation der expression des forkhead box p3 (foxp3) gens
|
WO2021202938A1
(en)
|
2020-04-03 |
2021-10-07 |
Creyon Bio, Inc. |
Oligonucleotide-based machine learning
|
WO2021216622A1
(en)
|
2020-04-21 |
2021-10-28 |
Aspen Neuroscience, Inc. |
Gene editing of gba1 in stem cells and method of use of cells differentiated therefrom
|
US20230165909A1
(en)
|
2020-04-21 |
2023-06-01 |
Aspen Neuroscience, Inc. |
Gene editing of lrrk2 in stem cells and method of use of cells differentiated therefrom
|
EP4138805A1
(de)
|
2020-04-23 |
2023-03-01 |
Genedit Inc. |
Polymer mit kationischen und hydrophoben seitenketten
|
US20230172987A1
(en)
|
2020-05-04 |
2023-06-08 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
US20230193212A1
(en)
|
2020-05-06 |
2023-06-22 |
Orchard Therapeutics (Europe) Limited |
Treatment for neurodegenerative diseases
|
WO2021226558A1
(en)
|
2020-05-08 |
2021-11-11 |
The Broad Institute, Inc. |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
JP2023527446A
(ja)
|
2020-05-29 |
2023-06-28 |
カー・ヴェー・エス ザート エス・エー ウント コー. カー・ゲー・アー・アー |
植物単数体の誘導
|
WO2021245435A1
(en)
|
2020-06-03 |
2021-12-09 |
Vilmorin & Cie |
Melon plants resistant to scab disease, aphids and powdery mildew
|
EP4161552A1
(de)
|
2020-06-05 |
2023-04-12 |
The Broad Institute, Inc. |
Zusammensetzungen und verfahren zur behandlung von neoplasien
|
WO2021245282A1
(en)
|
2020-06-05 |
2021-12-09 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobrfv
|
WO2022002989A1
(en)
|
2020-06-29 |
2022-01-06 |
KWS SAAT SE & Co. KGaA |
Boosting homology directed repair in plants
|
WO2022034474A1
(en)
|
2020-08-10 |
2022-02-17 |
Novartis Ag |
Treatments for retinal degenerative diseases
|
US20230363337A1
(en)
|
2020-10-02 |
2023-11-16 |
Vilmorin & Cie |
Melon with extended shelf life
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
US20230372397A1
(en)
|
2020-10-06 |
2023-11-23 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
US20240026369A1
(en)
|
2020-10-27 |
2024-01-25 |
KWS SAAT SE & Co. KGaA |
Use of enhanced pol theta activity for eukaryotic genome engineering
|
EP4242237A1
(de)
|
2020-11-06 |
2023-09-13 |
Editforce, Inc. |
Foki-nukleasedomänenvariante
|
EP4243608A1
(de)
|
2020-11-11 |
2023-09-20 |
Leibniz-Institut für Pflanzenbiochemie (IPB) |
Fusionsprotein zur bearbeitung endogener dna einer eukaryotischen zelle
|
EP4001429A1
(de)
|
2020-11-16 |
2022-05-25 |
Antibodies-Online GmbH |
Analyse von crispr-cas-bindungs- und spaltungsstellen, gefolgt von hochdurchsatzsequenzierung (abc-seq)
|
IL303102A
(en)
|
2020-12-03 |
2023-07-01 |
Vilmorin & Cie |
Tomato plants resistant to TOMMV, TOMV, TMV, TOBRFV and suitable resistant genes
|
JP2023554395A
(ja)
|
2020-12-17 |
2023-12-27 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Ctla-4及びpd-1阻害剤と併用した腫瘍浸潤リンパ球療法による治療
|
WO2022133149A1
(en)
|
2020-12-17 |
2022-06-23 |
Iovance Biotherapeutics, Inc. |
Treatment of cancers with tumor infiltrating lymphocytes
|
EP4267159A2
(de)
*
|
2020-12-22 |
2023-11-01 |
Ensoma, Inc. |
Helfervektoren für den adenoviralen serotyp-35
|
BR112023012460A2
(pt)
|
2020-12-23 |
2023-11-07 |
Flagship Pioneering Innovations V Inc |
Conjunto in vitro de capsídeos de anellovirus que envolvem rna
|
AU2021414617A1
(en)
|
2020-12-31 |
2023-08-10 |
Crispr Therapeutics Ag |
Universal donor cells
|
JP2024506557A
(ja)
|
2021-01-29 |
2024-02-14 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
修飾された腫瘍浸潤リンパ球を作製する方法及び養子細胞療法におけるそれらの使用
|
CA3212439A1
(en)
|
2021-03-19 |
2022-09-22 |
Michelle SIMPSON-ABELSON |
Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd69 selection and gene knockout in tils
|
IL307298A
(en)
|
2021-03-31 |
2023-11-01 |
Entrada Therapeutics Inc |
Cell-penetrating circular peptides
|
WO2022208489A1
(en)
|
2021-04-02 |
2022-10-06 |
Vilmorin & Cie |
Semi-determinate or determinate growth habit trait in cucurbita
|
WO2022225981A2
(en)
|
2021-04-19 |
2022-10-27 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
WO2022235929A1
(en)
|
2021-05-05 |
2022-11-10 |
Radius Pharmaceuticals, Inc. |
Animal model having homologous recombination of mouse pth1 receptor
|
AU2022271873A1
(en)
|
2021-05-10 |
2024-01-04 |
Entrada Therapeutics, Inc. |
Compositions and methods for intracellular therapeutics
|
EP4337261A2
(de)
|
2021-05-10 |
2024-03-20 |
Entrada Therapeutics, Inc. |
Zusammensetzungen und verfahren zur modulation des spleissens von mrna
|
WO2022240721A1
(en)
|
2021-05-10 |
2022-11-17 |
Entrada Therapeutics, Inc. |
Compositions and methods for modulating interferon regulatory factor-5 (irf-5) activity
|
JP2024519029A
(ja)
|
2021-05-17 |
2024-05-08 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Pd-1遺伝子編集された腫瘍浸潤リンパ球及び免疫療法におけるその使用
|
GB202107057D0
(en)
|
2021-05-18 |
2021-06-30 |
Univ York |
Glycosylation method
|
WO2022243437A1
(en)
|
2021-05-19 |
2022-11-24 |
KWS SAAT SE & Co. KGaA |
Sample preparation with oppositely oriented guide polynucleotides
|
WO2022256448A2
(en)
|
2021-06-01 |
2022-12-08 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing, or modifying genes
|
KR20240031238A
(ko)
|
2021-06-01 |
2024-03-07 |
아버 바이오테크놀로지스, 인크. |
Crispr 뉴클레이스를 포함하는 유전자 편집 시스템 및 이의 용도
|
CA3222341A1
(en)
|
2021-06-11 |
2022-12-15 |
Kunwoo Lee |
Biodegradable polymer comprising side chains with polyamine and polyalkylene oxide groups
|
WO2022266538A2
(en)
|
2021-06-18 |
2022-12-22 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing or modifying human genes
|
EP4359006A1
(de)
|
2021-06-23 |
2024-05-01 |
Entrada Therapeutics, Inc. |
Antisense-verbindungen und verfahren zum targeting von cug-wiederholungen
|
EP4367242A2
(de)
|
2021-07-07 |
2024-05-15 |
Omega Therapeutics, Inc. |
Zusammensetzungen und verfahren zur modulation der genexpression des sekretierten frizzled-rezeptorproteins 1 (sfrp1)
|
WO2023004074A2
(en)
|
2021-07-22 |
2023-01-26 |
Iovance Biotherapeutics, Inc. |
Method for cryopreservation of solid tumor fragments
|
EP4377446A1
(de)
|
2021-07-28 |
2024-06-05 |
Iovance Biotherapeutics, Inc. |
Behandlung von krebspatienten mit tumorinfiltrierenden lymphozytentherapien in kombination mit kras-hemmern
|
EP4376596A1
(de)
|
2021-07-30 |
2024-06-05 |
KWS SAAT SE & Co. KGaA |
Pflanzen mit verbesserter verdaulichkeit und markerhaplotypen
|
WO2023012325A1
(en)
|
2021-08-06 |
2023-02-09 |
Vilmorin & Cie |
Resistance to leveillula taurica in pepper
|
WO2023039586A1
(en)
|
2021-09-10 |
2023-03-16 |
Agilent Technologies, Inc. |
Guide rnas with chemical modification for prime editing
|
EP4166670A1
(de)
|
2021-10-18 |
2023-04-19 |
KWS SAAT SE & Co. KGaA |
Auf pflanzenetiketten basierte unkrautbekämpfung
|
CA3235824A1
(en)
|
2021-10-27 |
2023-05-04 |
Frederick G. Vogt |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
WO2023077148A1
(en)
|
2021-11-01 |
2023-05-04 |
Tome Biosciences, Inc. |
Single construct platform for simultaneous delivery of gene editing machinery and nucleic acid cargo
|
WO2023081756A1
(en)
|
2021-11-03 |
2023-05-11 |
The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone |
Precise genome editing using retrons
|
AU2022388729A1
(en)
|
2021-11-10 |
2024-05-16 |
Iovance Biotherapeutics, Inc. |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
WO2023093862A1
(en)
|
2021-11-26 |
2023-06-01 |
Epigenic Therapeutics Inc. |
Method of modulating pcsk9 and uses thereof
|
GB202118058D0
(en)
|
2021-12-14 |
2022-01-26 |
Univ Warwick |
Methods to increase yields in crops
|
US20230279442A1
(en)
|
2021-12-15 |
2023-09-07 |
Versitech Limited |
Engineered cas9-nucleases and method of use thereof
|
TW202342757A
(zh)
|
2021-12-17 |
2023-11-01 |
美商薩那生物科技公司 |
經修飾副黏液病毒科附著醣蛋白
|
WO2023115039A2
(en)
|
2021-12-17 |
2023-06-22 |
Sana Biotechnology, Inc. |
Modified paramyxoviridae fusion glycoproteins
|
WO2023118349A1
(en)
|
2021-12-21 |
2023-06-29 |
Alia Therapeutics Srl |
Type ii cas proteins and applications thereof
|
WO2023122764A1
(en)
|
2021-12-22 |
2023-06-29 |
Tome Biosciences, Inc. |
Co-delivery of a gene editor construct and a donor template
|
WO2023122800A1
(en)
|
2021-12-23 |
2023-06-29 |
University Of Massachusetts |
Therapeutic treatment for fragile x-associated disorder
|
WO2023133595A2
(en)
|
2022-01-10 |
2023-07-13 |
Sana Biotechnology, Inc. |
Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
|
WO2023141602A2
(en)
|
2022-01-21 |
2023-07-27 |
Renagade Therapeutics Management Inc. |
Engineered retrons and methods of use
|
WO2023147488A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Cytokine associated tumor infiltrating lymphocytes compositions and methods
|
WO2023150518A1
(en)
|
2022-02-01 |
2023-08-10 |
Sana Biotechnology, Inc. |
Cd3-targeted lentiviral vectors and uses thereof
|
WO2023150647A1
(en)
|
2022-02-02 |
2023-08-10 |
Sana Biotechnology, Inc. |
Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
|
WO2023167882A1
(en)
|
2022-03-01 |
2023-09-07 |
Artisan Development Labs, Inc. |
Composition and methods for transgene insertion
|
WO2023194359A1
(en)
|
2022-04-04 |
2023-10-12 |
Alia Therapeutics Srl |
Compositions and methods for treatment of usher syndrome type 2a
|
EP4256950A1
(de)
|
2022-04-06 |
2023-10-11 |
Vilmorin et Cie |
Toleranz gegenüber cgmmv in gurken
|
WO2023196877A1
(en)
|
2022-04-06 |
2023-10-12 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
WO2023201369A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
WO2023205744A1
(en)
|
2022-04-20 |
2023-10-26 |
Tome Biosciences, Inc. |
Programmable gene insertion compositions
|
WO2023215831A1
(en)
|
2022-05-04 |
2023-11-09 |
Tome Biosciences, Inc. |
Guide rna compositions for programmable gene insertion
|
WO2023219933A1
(en)
|
2022-05-09 |
2023-11-16 |
Entrada Therapeutics, Inc. |
Compositions and methods for delivery of nucleic acid therapeutics
|
WO2023220608A1
(en)
|
2022-05-10 |
2023-11-16 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with an il-15r agonist
|
WO2023225410A2
(en)
|
2022-05-20 |
2023-11-23 |
Artisan Development Labs, Inc. |
Systems and methods for assessing risk of genome editing events
|
WO2023225670A2
(en)
|
2022-05-20 |
2023-11-23 |
Tome Biosciences, Inc. |
Ex vivo programmable gene insertion
|
WO2023230549A2
(en)
|
2022-05-25 |
2023-11-30 |
Flagship Pioneering Innovations Vii, Llc |
Compositions and methods for modulation of tumor suppressors and oncogenes
|
WO2023230570A2
(en)
|
2022-05-25 |
2023-11-30 |
Flagship Pioneering Innovations Vii, Llc |
Compositions and methods for modulating genetic drivers
|
WO2023230578A2
(en)
|
2022-05-25 |
2023-11-30 |
Flagship Pioneering Innovations Vii, Llc |
Compositions and methods for modulating circulating factors
|
WO2023230573A2
(en)
|
2022-05-25 |
2023-11-30 |
Flagship Pioneering Innovations Vii, Llc |
Compositions and methods for modulation of immune responses
|
WO2023230566A2
(en)
|
2022-05-25 |
2023-11-30 |
Flagship Pioneering Innovations Vii, Llc |
Compositions and methods for modulating cytokines
|
GB2621813A
(en)
|
2022-06-30 |
2024-02-28 |
Univ Newcastle |
Preventing disease recurrence in Mitochondrial replacement therapy
|
WO2024005864A1
(en)
|
2022-06-30 |
2024-01-04 |
Inari Agriculture Technology, Inc. |
Compositions, systems, and methods for genome editing
|
EP4299733A1
(de)
|
2022-06-30 |
2024-01-03 |
Inari Agriculture Technology, Inc. |
Zusammensetzungen, systeme und verfahren zum genomeditieren
|
WO2024005863A1
(en)
|
2022-06-30 |
2024-01-04 |
Inari Agriculture Technology, Inc. |
Compositions, systems, and methods for genome editing
|
EP4299739A1
(de)
|
2022-06-30 |
2024-01-03 |
Inari Agriculture Technology, Inc. |
Zusammensetzungen und verfahren zur genomeditierung
|
JP7152094B1
(ja)
*
|
2022-06-30 |
2022-10-12 |
リージョナルフィッシュ株式会社 |
tracrRNAユニット、及びゲノム編集方法
|
WO2024020346A2
(en)
|
2022-07-18 |
2024-01-25 |
Renagade Therapeutics Management Inc. |
Gene editing components, systems, and methods of use
|
WO2024020587A2
(en)
|
2022-07-22 |
2024-01-25 |
Tome Biosciences, Inc. |
Pleiopluripotent stem cell programmable gene insertion
|
WO2024044655A1
(en)
|
2022-08-24 |
2024-02-29 |
Sana Biotechnology, Inc. |
Delivery of heterologous proteins
|
WO2024044723A1
(en)
|
2022-08-25 |
2024-02-29 |
Renagade Therapeutics Management Inc. |
Engineered retrons and methods of use
|
WO2024042199A1
(en)
|
2022-08-26 |
2024-02-29 |
KWS SAAT SE & Co. KGaA |
Use of paired genes in hybrid breeding
|
WO2024053964A1
(ko)
*
|
2022-09-06 |
2024-03-14 |
주식회사 툴젠 |
캄필로박터 제주니 유래 cas9의 가이드 rna 구조변화를 통한 유전자교정 향상 시스템
|
WO2024056880A2
(en)
|
2022-09-16 |
2024-03-21 |
Alia Therapeutics Srl |
Enqp type ii cas proteins and applications thereof
|
WO2024064838A1
(en)
|
2022-09-21 |
2024-03-28 |
Sana Biotechnology, Inc. |
Lipid particles comprising variant paramyxovirus attachment glycoproteins and uses thereof
|
WO2024081820A1
(en)
|
2022-10-13 |
2024-04-18 |
Sana Biotechnology, Inc. |
Viral particles targeting hematopoietic stem cells
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
WO2024098027A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd103 selection
|
WO2024102434A1
(en)
|
2022-11-10 |
2024-05-16 |
Senda Biosciences, Inc. |
Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs
|
WO2024105162A1
(en)
|
2022-11-16 |
2024-05-23 |
Alia Therapeutics Srl |
Type ii cas proteins and applications thereof
|
CN115982034B
(zh)
*
|
2022-12-30 |
2023-11-28 |
云舟生物科技(广州)股份有限公司 |
载体构建系统虚拟终端的测试方法、存储介质及电子设备
|