GR1000172B - Βελτιωσεις εις η εν σχεσει προς τις σωματοστατινες. - Google Patents
Βελτιωσεις εις η εν σχεσει προς τις σωματοστατινες.Info
- Publication number
- GR1000172B GR1000172B GR880100458A GR880100458A GR1000172B GR 1000172 B GR1000172 B GR 1000172B GR 880100458 A GR880100458 A GR 880100458A GR 880100458 A GR880100458 A GR 880100458A GR 1000172 B GR1000172 B GR 1000172B
- Authority
- GR
- Greece
- Prior art keywords
- bodies
- complete
- pharmaceutical composition
- somatostatin analog
- injected
- Prior art date
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878716326A GB8716326D0 (en) | 1987-07-10 | 1987-07-10 | Organic compounds |
| GB878716324A GB8716324D0 (en) | 1987-07-10 | 1987-07-10 | Organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GR880100458A GR880100458A (en) | 1989-04-12 |
| GR1000172B true GR1000172B (el) | 1991-11-15 |
Family
ID=26292476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR880100458A GR1000172B (el) | 1987-07-10 | 1988-07-08 | Βελτιωσεις εις η εν σχεσει προς τις σωματοστατινες. |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US5753618A (https=) |
| JP (1) | JP2578477B2 (https=) |
| AU (1) | AU618270B2 (https=) |
| BE (1) | BE1001079A4 (https=) |
| CA (1) | CA1328402C (https=) |
| CH (1) | CH677449A5 (https=) |
| CS (1) | CS411591A3 (https=) |
| CY (2) | CY1631A (https=) |
| DE (2) | DE3822557C2 (https=) |
| DK (2) | DK174125B1 (https=) |
| ES (1) | ES2010561A6 (https=) |
| FI (1) | FI93308C (https=) |
| FR (1) | FR2617714B1 (https=) |
| GB (1) | GB2208200B (https=) |
| GR (1) | GR1000172B (https=) |
| HK (1) | HK16492A (https=) |
| HU (1) | HU203480B (https=) |
| IE (1) | IE61908B1 (https=) |
| IL (1) | IL87044A0 (https=) |
| LU (1) | LU87268A1 (https=) |
| MY (2) | MY109309A (https=) |
| NL (1) | NL194823C (https=) |
| NO (1) | NO179359C (https=) |
| NZ (1) | NZ225340A (https=) |
| PT (1) | PT87957B (https=) |
| SE (2) | SE503191C2 (https=) |
| SG (1) | SG3692G (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8813339D0 (en) * | 1988-06-06 | 1988-07-13 | Sandoz Ltd | Improvements in/relating to organic compounds |
| US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
| PH30995A (en) * | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
| RU2128055C1 (ru) * | 1992-12-07 | 1999-03-27 | Такеда Кемикал Индастриз Лтд. | Фармацевтическая композиция замедленного высвобождения и способ ее получения |
| US5626945A (en) * | 1993-09-28 | 1997-05-06 | International Paper Company | Repulpable, water repellant paperboard |
| US6355613B1 (en) * | 1996-07-31 | 2002-03-12 | Peptor Limited | Conformationally constrained backbone cyclized somatostatin analogs |
| WO1998008528A1 (en) * | 1996-08-30 | 1998-03-05 | Biomeasure Incorporated | Method of inhibiting fibrosis with a somatostatin agonist |
| ES2167189B1 (es) * | 1999-12-17 | 2003-04-01 | Lipotec Sa | Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos |
| US6316414B1 (en) | 2000-07-31 | 2001-11-13 | Dabur Research Foundation | Somatostatin analogs for the treatment of cancer |
| BR0210915A (pt) * | 2001-06-08 | 2004-06-08 | Sod Conseils Rech Applic | Análogos quiméricos de somatostatina-dopamina |
| TWI287986B (en) * | 2001-12-13 | 2007-10-11 | Novartis Ag | Use of Epothilones for the treatment of the carcinoid syndrome |
| US20030207811A1 (en) * | 2002-05-03 | 2003-11-06 | Schrier Bruce K. | Method of treating retinopathy of prematurity using somatostatin analogs |
| AR044852A1 (es) * | 2003-06-24 | 2005-10-05 | Novartis Ag | Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina |
| GB0428151D0 (en) * | 2004-12-22 | 2005-01-26 | Novartis Ag | Organic compounds |
| ES2383303T3 (es) | 2005-11-10 | 2012-06-20 | Chemi S.P.A. | Formulaciones de inhibidores de la liberación prolongada de la hormona del crecimiento análogos de la somatostatina |
| ES2444890T3 (es) * | 2006-03-31 | 2014-02-27 | Erasmus University Medical Center Rotterdam | Nueva composición para el control del crecimiento tumoral |
| WO2008039482A2 (en) * | 2006-09-26 | 2008-04-03 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
| US9517240B2 (en) | 2006-09-26 | 2016-12-13 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
| US20090325863A1 (en) * | 2008-06-13 | 2009-12-31 | Kleinberg David L | Somatostatin analogs and IGF-I inhibition for breast cancer prevention |
| GB201016436D0 (en) | 2010-09-30 | 2010-11-17 | Q Chip Ltd | Method of making solid beads |
| GB201016433D0 (en) | 2010-09-30 | 2010-11-17 | Q Chip Ltd | Apparatus and method for making solid beads |
| US8629103B2 (en) * | 2010-12-02 | 2014-01-14 | New York University | Treatment of non-proliferative cystic disease of the breast |
| BR112013030874B8 (pt) | 2011-06-02 | 2021-09-14 | Univ California | Uso de uma theta-defensina ou análogo da mesma para tratar uma condição inflamatória crônica |
| TWI523863B (zh) | 2012-11-01 | 2016-03-01 | 艾普森藥品公司 | 體抑素－多巴胺嵌合體類似物 |
| EP2914276A4 (en) | 2012-11-01 | 2016-07-13 | Ipsen Pharma Sas | SOMATOSTATIN ANALOGA AND DIMERE OUT |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH621770A5 (en) * | 1976-02-23 | 1981-02-27 | Sandoz Ag | Process for the preparation of novel peptide compounds |
| DE2860734D1 (en) * | 1977-06-08 | 1981-09-03 | Merck & Co Inc | Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them |
| LU78191A1 (de) * | 1977-09-28 | 1979-05-25 | Ciba Geigy Ag | Verfahren zur herstellung von neuen cyclopeptiden |
| US4328214A (en) * | 1979-07-04 | 1982-05-04 | Ciba-Geigy Corporation | Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture |
| US4900730A (en) * | 1981-01-14 | 1990-02-13 | Toyo Jozo Co., Ltd. | Preparation which promotes the absorption of peptides |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| JPS57188526A (en) * | 1981-05-14 | 1982-11-19 | Takeda Chem Ind Ltd | Peptide-containing pharmaceutical preparation |
| US4374060A (en) * | 1981-07-15 | 1983-02-15 | Merck & Co., Inc. | Process for the preparation of cyclic hexapeptide |
| EP0083305B1 (de) * | 1981-12-24 | 1985-07-10 | Ciba-Geigy Ag | Cyclische Octapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung |
| US4522813A (en) * | 1983-10-27 | 1985-06-11 | Merck & Co., Inc. | Cyclic hexapeptide somatostatin analogs |
| HU195810B (en) * | 1984-12-24 | 1988-07-28 | Sandoz Ag | Process for preparing new 8alpha-acyl-amino-ergoline derivatives and pharmaceutical compositions containing such compounds |
| US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
| US4650787A (en) * | 1985-04-25 | 1987-03-17 | Schally Andrew Victor | Biologically active octapeptides |
| ZW14486A1 (en) * | 1985-07-29 | 1986-10-22 | Smithkline Beckman Corp | Pharmaceutical dosage unit |
| JPH085913B2 (ja) * | 1985-09-12 | 1996-01-24 | ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド | 治療用ソマトスタチン同族体 |
| GR862206B (en) * | 1985-09-12 | 1986-12-31 | Univ Tulane | Therapeutic somatostatin analogs |
| HU198626B (en) * | 1986-05-27 | 1989-11-28 | Sandoz Ag | Process for producing pharmaceutical compositions comprising somatostatin analogues as active ingredient |
| NL194729C (nl) * | 1986-10-13 | 2003-01-07 | Novartis Ag | Werkwijze voor de bereiding van peptidealcoholen via vaste fase. |
| AU639371B2 (en) * | 1987-07-10 | 1993-07-22 | Novartis Ag | Method of treating breast cancer |
| US5187150A (en) * | 1987-10-14 | 1993-02-16 | Debiopharm S.A. | Polyester-based composition for the controlled release of polypeptide medicinal substances |
| AU2284588A (en) * | 1988-09-26 | 1990-03-29 | Sandoz Ltd. | Improvements in or relating to organic compounds |
| MY106120A (en) * | 1988-12-05 | 1995-03-31 | Novartis Ag | Peptide derivatives. |
| US5384309A (en) * | 1989-07-17 | 1995-01-24 | Genentech, Inc. | Cyclized peptides and their use as platelet aggregation inhibitors |
| JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
-
1988
- 1988-07-04 DE DE3822557A patent/DE3822557C2/de not_active Expired - Lifetime
- 1988-07-04 DE DE3845000A patent/DE3845000C2/de not_active Expired - Lifetime
- 1988-07-05 CH CH2556/88A patent/CH677449A5/de not_active IP Right Cessation
- 1988-07-06 GB GB8816024A patent/GB2208200B/en not_active Expired - Lifetime
- 1988-07-07 MY MYPI93000569A patent/MY109309A/en unknown
- 1988-07-07 MY MYPI88000750A patent/MY103746A/en unknown
- 1988-07-08 AU AU18893/88A patent/AU618270B2/en not_active Expired
- 1988-07-08 PT PT87957A patent/PT87957B/pt not_active IP Right Cessation
- 1988-07-08 CA CA000571592A patent/CA1328402C/en not_active Expired - Lifetime
- 1988-07-08 FI FI883261A patent/FI93308C/fi active IP Right Grant
- 1988-07-08 GR GR880100458A patent/GR1000172B/el not_active IP Right Cessation
- 1988-07-08 HU HU883604A patent/HU203480B/hu unknown
- 1988-07-08 SE SE8802569A patent/SE503191C2/sv not_active IP Right Cessation
- 1988-07-08 NO NO883054A patent/NO179359C/no not_active IP Right Cessation
- 1988-07-08 FR FR888809439A patent/FR2617714B1/fr not_active Expired - Lifetime
- 1988-07-08 IL IL87044A patent/IL87044A0/xx not_active IP Right Cessation
- 1988-07-08 IE IE209188A patent/IE61908B1/en not_active IP Right Cessation
- 1988-07-08 DK DK198803854A patent/DK174125B1/da not_active IP Right Cessation
- 1988-07-08 ES ES8802161A patent/ES2010561A6/es not_active Expired
- 1988-07-08 NZ NZ225340A patent/NZ225340A/en unknown
- 1988-07-08 LU LU87268A patent/LU87268A1/fr unknown
- 1988-07-08 NL NL8801734A patent/NL194823C/nl not_active IP Right Cessation
- 1988-07-09 JP JP63171703A patent/JP2578477B2/ja not_active Expired - Lifetime
- 1988-07-11 BE BE8800803A patent/BE1001079A4/fr not_active IP Right Cessation
-
1991
- 1991-12-27 CS CS914115A patent/CS411591A3/cs unknown
-
1992
- 1992-01-13 SG SG36/92A patent/SG3692G/en unknown
- 1992-02-27 HK HK164/92A patent/HK16492A/xx not_active IP Right Cessation
- 1992-07-10 CY CY1631A patent/CY1631A/en unknown
- 1992-07-10 CY CY1632A patent/CY1632A/en unknown
-
1993
- 1993-04-20 SE SE19939301290A patent/SE9301290D0/xx not_active Application Discontinuation
-
1995
- 1995-06-06 US US08/471,706 patent/US5753618A/en not_active Expired - Lifetime
-
1998
- 1998-02-11 US US09/022,079 patent/US6066616A/en not_active Expired - Fee Related
-
2001
- 2001-04-04 DK DK200100558A patent/DK174476B1/da not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GR1000172B (el) | Βελτιωσεις εις η εν σχεσει προς τις σωματοστατινες. | |
| ATE358176T1 (de) | Menschliche dnase | |
| FI883936A7 (fi) | Sokeritaudin hoito, hoidossa käyttökelpoiset valmisteet ja niiden valmistus | |
| DE68906161D1 (de) | Ballon fuer medizinische einrichtung und dessen herstellung. | |
| ATE63813T1 (de) | Pharmazeutische zusammensetzungen von dihydrocodeine/ibuprofen und verfahren. | |
| DE3883985D1 (de) | Ärztliches instrument und dessen herstellung. | |
| FI882742A7 (fi) | Hoitavia aineita ja niitä sisältäviä koostumuksia. | |
| NO951592D0 (no) | Fremgangsmåte for fremstilling av et transdermalt terapeutisk system | |
| ATE179887T1 (de) | Arzneimittelzubereitung | |
| ATE54826T1 (de) | Thymusextraktfraktionen enthaltende pharmazeutische zusammensetzung. | |
| FI873106A0 (fi) | Menetelmä jatkuvavapautteisen lääkevalmisteen valmistamiseksi | |
| ZA855822B (en) | Pharmaceutical compositions for the treatment of involutional brain syndromes and mental decay | |
| DE68912020D1 (de) | N-2,3-Butadienyl-tri-aminoalkanderivate. | |
| GR880100775A (el) | Παράγοντας ενεργοποιήσεως ουδετεροφίλων. | |
| ATE64300T1 (de) | Wirkstoffe zur anwendung bei der behandlung von tumoren. | |
| IT1232819B (it) | Impiego di sorgenti di nucleobasi per stimolare la funzione immunitaria, relativo procedimento e composizioni farmaceutiche contenenti una tale sorgente di nucleobasi | |
| DE3771584D1 (de) | Zusammensetzungen und anwendung von interleukin-2 und/oder interferon-beta und des tumor-necrosis-faktors fuer eine kombinationstherapie oder zur herstellung von arzneimitteln oder formulierungen. | |
| DE3863200D1 (de) | In der krebstherapie verwendbare zusammensetzung auf der basis von aminosaeure und vitaminen. | |
| ES2052670T3 (es) | Utilizacion de derivados de 2-pirimidinil-1-piperazina. | |
| FI873408A7 (fi) | Anesteettinen koostumus ja menetelmä sen käyttämiseksi. | |
| TR199700842T1 (xx) | �nsan DNase I Varyantlar�. | |
| GR880100401A (el) | 8α-ακυλαμινεργολινη,παρασκευη της και φαρμακευτικες συνθεσεις που την περιεχουν. | |
| ES8704903A1 (es) | Un metodo para preparar 6-cloro-2-metil-1h-2,3,4,5-tetrahidro-3-benzazepen-n-oxido. | |
| ES8801624A1 (es) | Procedimiento para preparar disulfuros heterociclicos | |
| ATE69549T1 (de) | Erzeugnisse, enthaltend gallopamil und prazosin. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Right expired |