PT87957A - Processo para a preparacao de uma composicao farmaceutica contendo um analogo da somatostatina - Google Patents

Processo para a preparacao de uma composicao farmaceutica contendo um analogo da somatostatina

Info

Publication number
PT87957A
PT87957A PT87957A PT8795788A PT87957A PT 87957 A PT87957 A PT 87957A PT 87957 A PT87957 A PT 87957A PT 8795788 A PT8795788 A PT 8795788A PT 87957 A PT87957 A PT 87957A
Authority
PT
Portugal
Prior art keywords
somatatostan
analogue
preparation
pharmaceutical composition
composition containing
Prior art date
Application number
PT87957A
Other languages
English (en)
Other versions
PT87957B (pt
Inventor
Thomas Cavanak
Alan Harris
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878716324A external-priority patent/GB8716324D0/en
Priority claimed from GB878716326A external-priority patent/GB8716326D0/en
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT87957A publication Critical patent/PT87957A/pt
Publication of PT87957B publication Critical patent/PT87957B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT87957A 1987-07-10 1988-07-08 Processo para a preparacao de uma composicao farmaceutica contendo um analogo da somatostatina PT87957B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878716324A GB8716324D0 (en) 1987-07-10 1987-07-10 Organic compounds
GB878716326A GB8716326D0 (en) 1987-07-10 1987-07-10 Organic compounds

Publications (2)

Publication Number Publication Date
PT87957A true PT87957A (pt) 1989-06-30
PT87957B PT87957B (pt) 1995-03-01

Family

ID=26292476

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87957A PT87957B (pt) 1987-07-10 1988-07-08 Processo para a preparacao de uma composicao farmaceutica contendo um analogo da somatostatina

Country Status (27)

Country Link
US (2) US5753618A (pt)
JP (1) JP2578477B2 (pt)
AU (1) AU618270B2 (pt)
BE (1) BE1001079A4 (pt)
CA (1) CA1328402C (pt)
CH (1) CH677449A5 (pt)
CS (1) CS411591A3 (pt)
CY (2) CY1631A (pt)
DE (2) DE3845000C2 (pt)
DK (2) DK174125B1 (pt)
ES (1) ES2010561A6 (pt)
FI (1) FI93308C (pt)
FR (1) FR2617714B1 (pt)
GB (1) GB2208200B (pt)
GR (1) GR1000172B (pt)
HK (1) HK16492A (pt)
HU (1) HU203480B (pt)
IE (1) IE61908B1 (pt)
IL (1) IL87044A0 (pt)
LU (1) LU87268A1 (pt)
MY (2) MY103746A (pt)
NL (1) NL194823C (pt)
NO (1) NO179359C (pt)
NZ (1) NZ225340A (pt)
PT (1) PT87957B (pt)
SE (2) SE503191C2 (pt)
SG (1) SG3692G (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
PH30995A (en) * 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5626945A (en) * 1993-09-28 1997-05-06 International Paper Company Repulpable, water repellant paperboard
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
WO1998008528A1 (en) 1996-08-30 1998-03-05 Biomeasure Incorporated Method of inhibiting fibrosis with a somatostatin agonist
ES2167189B1 (es) * 1999-12-17 2003-04-01 Lipotec Sa Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
US6316414B1 (en) 2000-07-31 2001-11-13 Dabur Research Foundation Somatostatin analogs for the treatment of cancer
WO2002100888A1 (en) * 2001-06-08 2002-12-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Somatostatin-dopamine chimeric analogs
TWI287986B (en) * 2001-12-13 2007-10-11 Novartis Ag Use of Epothilones for the treatment of the carcinoid syndrome
US20030207811A1 (en) * 2002-05-03 2003-11-06 Schrier Bruce K. Method of treating retinopathy of prematurity using somatostatin analogs
ATE549011T1 (de) 2005-11-10 2012-03-15 Chemi Spa Formulierungen mit verzögerter freisetzung, die somatostatin-analoge wachstumshormoninhibitoren enthalten
ES2444890T3 (es) * 2006-03-31 2014-02-27 Erasmus University Medical Center Rotterdam Nueva composición para el control del crecimiento tumoral
US20100160275A1 (en) * 2006-09-26 2010-06-24 Lee Eva Y H P Methods and compositions for cancer prevention and treatment
US9517240B2 (en) 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20090325863A1 (en) * 2008-06-13 2009-12-31 Kleinberg David L Somatostatin analogs and IGF-I inhibition for breast cancer prevention
GB201016433D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Apparatus and method for making solid beads
GB201016436D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Method of making solid beads
US8629103B2 (en) * 2010-12-02 2014-01-14 New York University Treatment of non-proliferative cystic disease of the breast
CN103732239A (zh) * 2011-06-02 2014-04-16 加利福尼亚大学董事会 利用θ-防御素的炎性蛋白酶的阻断
CN104768565B (zh) 2012-11-01 2017-04-26 益普生制药股份有限公司 促生长素抑制素类似物及其二聚体
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH621770A5 (en) * 1976-02-23 1981-02-27 Sandoz Ag Process for the preparation of novel peptide compounds
EP0000053B1 (en) * 1977-06-08 1981-05-27 Merck & Co. Inc. Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4328214A (en) * 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
US4900730A (en) * 1981-01-14 1990-02-13 Toyo Jozo Co., Ltd. Preparation which promotes the absorption of peptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
US4374060A (en) * 1981-07-15 1983-02-15 Merck & Co., Inc. Process for the preparation of cyclic hexapeptide
EP0083305B1 (de) * 1981-12-24 1985-07-10 Ciba-Geigy Ag Cyclische Octapeptide und pharmazeutische Präparate davon, sowie Verfahren zur Herstellung derselben und ihre Anwendung
US4522813A (en) * 1983-10-27 1985-06-11 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
NL8701143A (nl) * 1986-05-27 1987-12-16 Sandoz Ag Farmaceutische preparaten.
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
US5187150A (en) * 1987-10-14 1993-02-16 Debiopharm S.A. Polyester-based composition for the controlled release of polypeptide medicinal substances
AU2284588A (en) * 1988-09-26 1990-03-29 Sandoz Ltd. Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体

Also Published As

Publication number Publication date
FI93308B (fi) 1994-12-15
MY109309A (en) 1997-01-31
SG3692G (en) 1992-03-20
IL87044A0 (en) 1988-12-30
JPS6431728A (en) 1989-02-02
HUT47865A (en) 1989-04-28
DK385488A (da) 1989-01-11
GB2208200A (en) 1989-03-15
JP2764041B2 (ja) 1998-06-11
FI93308C (fi) 1995-03-27
NL194823B (nl) 2002-12-02
SE8802569L (sv) 1989-01-11
MY103746A (en) 1993-09-30
CH677449A5 (pt) 1991-05-31
CA1328402C (en) 1994-04-12
NO179359B (no) 1996-06-17
ES2010561A6 (es) 1989-11-16
PT87957B (pt) 1995-03-01
IE882091L (en) 1989-01-10
HU203480B (en) 1991-08-28
NL8801734A (nl) 1989-02-01
AU618270B2 (en) 1991-12-19
AU1889388A (en) 1989-01-12
NL194823C (nl) 2003-04-03
SE503191C2 (sv) 1996-04-15
CY1632A (en) 1992-07-10
NO883054D0 (no) 1988-07-08
DK174476B1 (da) 2003-04-14
IE61908B1 (en) 1994-11-30
JP2578477B2 (ja) 1997-02-05
JPH0748272A (ja) 1995-02-21
CS411591A3 (en) 1992-06-17
DE3845000C2 (de) 1998-11-19
GR880100458A (en) 1989-04-12
DE3822557C2 (de) 1998-07-02
NZ225340A (en) 1991-05-28
DK174125B1 (da) 2002-07-01
DK200100558A (da) 2001-04-04
LU87268A1 (fr) 1989-03-08
SE9301290D0 (sv) 1993-04-20
FR2617714A1 (fr) 1989-01-13
SE8802569D0 (sv) 1988-07-08
SE9301290A0 (sv) 1993-04-20
NO883054L (no) 1989-01-11
DE3822557A1 (de) 1989-01-19
CY1631A (en) 1992-07-10
GR1000172B (el) 1991-11-15
FR2617714B1 (fr) 1991-09-20
HK16492A (en) 1992-03-06
FI883261A0 (fi) 1988-07-08
US6066616A (en) 2000-05-23
FI883261A (fi) 1989-01-11
DK385488D0 (da) 1988-07-08
US5753618A (en) 1998-05-19
GB8816024D0 (en) 1988-08-10
NO179359C (no) 1996-09-25
BE1001079A4 (fr) 1989-07-04
GB2208200B (en) 1991-11-27

Similar Documents

Publication Publication Date Title
PT87957A (pt) Processo para a preparacao de uma composicao farmaceutica contendo um analogo da somatostatina
PT83459B (pt) Processo para a preparacao de composicoes farmaceuticas contendo o ester de 1-acetoxietilo da cefuroxima
PT91731A (pt) Processo para a preparacao de composicoes farmaceuticas contendo ciclosporinas
PT90120A (pt) Processo para a preparacao de uma composicao farmaceutica contendo deprenil para administracao sistemica transdermica
PT89276A (pt) Processo para a preparacao de uma formulacao farmaceutica de libertacao prolongada
PT83756B (pt) Processo para a preparacao de composicoes farmaceuticas com libertacao controlada
BR8805820A (pt) Processo para a preparacao de uma composicao polimerica
PT84785B (pt) Processo para a preparacao de composicoes farmceuticas que contem omeprazole para administracao por via oral
PT89094A (pt) Processo para a preparacao de 1-aril-3-quinolina-e 1-aril-3-isoquinolina-carboxamidas e de composicoes farmaceuticas que as contem
PT88612A (pt) Processo para a preparacao de composicoes farmaceuticas contendo um agente anti-calculo dental
PT84786B (pt) Processo para a preparacao de composicoes farmaceuticas que contem compostos acidos labeis parea administracao por via oral
BR8802051A (pt) Processo para a preparacao de uma composicao detergente granular
BR8802050A (pt) Processo para a preparacao de uma composicao detergente granular
PT87190A (pt) Processo para a preparacao de composicoes farmaceuticas para a reducao dos efeitos indesejaveis das beta-lactaminas
PT87880A (pt) Processo para a preparacao de composicoes farmaceuticas anti-virais que contem ciclo-dextrinas
PT91454A (pt) Processo para a preparacao de uma composicao de para supositorios contraceptivos de longa duracao
PT87958A (pt) Processo para a preparacao de composicoes farmaceuticas, contendo antagonistas 5ht-3
PT88200A (pt) Processo para a preparacao de uma composicao para o tratamento da pele
PT86819A (pt) Process for the preparation of novel insulin derivatives and of pharmaceutical compositions containing the same
PT88225A (pt) Processo para a preparacao de formulacoes farmaceuticas contendo di-hidropiridinas
PT96352A (pt) Processo para a preparacao de uma composicao aperfeicoada para tratamento capilar
PT90888A (pt) Processo para a preparacao de composicoes farmaceuticas contendo prostaglandinas
PT84187B (pt) Processo para a preparacao de novos derivados da isoquinolina e de composicoes farmaceuticas que os contem
PT90435A (pt) Processo aperfeicoado para a preparacao de uma cetimina
BR8800430A (pt) Processo para a preparacao de uma composicao termoplastica

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940818

PC3A Transfer or assignment

Free format text: 971017 NOVARTIS AG CH

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20090818