DE68912020D1 - N-2,3-Butadienyl-tri-aminoalkanderivate. - Google Patents

N-2,3-Butadienyl-tri-aminoalkanderivate.

Info

Publication number
DE68912020D1
DE68912020D1 DE89114354T DE68912020T DE68912020D1 DE 68912020 D1 DE68912020 D1 DE 68912020D1 DE 89114354 T DE89114354 T DE 89114354T DE 68912020 T DE68912020 T DE 68912020T DE 68912020 D1 DE68912020 D1 DE 68912020D1
Authority
DE
Germany
Prior art keywords
butadienyl
tri
aminoalkane
derivatives
polyamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89114354T
Other languages
English (en)
Other versions
DE68912020T2 (de
Inventor
Philippe Bey
David M Stemerick
Michael L Edwards
Alan J Bitonti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE68912020D1 publication Critical patent/DE68912020D1/de
Application granted granted Critical
Publication of DE68912020T2 publication Critical patent/DE68912020T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21—Monoamines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE89114354T 1988-08-04 1989-08-03 N-2,3-Butadienyl-tri-aminoalkanderivate. Expired - Fee Related DE68912020T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/228,620 US4935449A (en) 1988-08-04 1988-08-04 N-2,3-butadienyl tri- and tetraaminoalkane derivatives

Publications (2)

Publication Number Publication Date
DE68912020D1 true DE68912020D1 (de) 1994-02-17
DE68912020T2 DE68912020T2 (de) 1994-04-28

Family

ID=22857945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89114354T Expired - Fee Related DE68912020T2 (de) 1988-08-04 1989-08-03 N-2,3-Butadienyl-tri-aminoalkanderivate.

Country Status (19)

Country Link
US (1) US4935449A (de)
EP (1) EP0353752B1 (de)
JP (1) JP2722255B2 (de)
KR (1) KR0144155B1 (de)
CN (1) CN1039800A (de)
AT (1) ATE99669T1 (de)
AU (1) AU617502B2 (de)
CA (1) CA1321603C (de)
DE (1) DE68912020T2 (de)
DK (1) DK381189A (de)
ES (1) ES2061826T3 (de)
FI (1) FI893681A (de)
HU (1) HU207833B (de)
IL (1) IL91184A0 (de)
NO (1) NO172043C (de)
NZ (1) NZ230155A (de)
PH (1) PH27214A (de)
PT (1) PT91365A (de)
ZA (1) ZA895840B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111794D0 (en) * 1991-05-31 1991-07-24 Robins David J Antifungal compounds
AU690618B2 (en) * 1993-12-27 1998-04-30 Novartis Ag Unsaturate amino compounds for use as anticancer and antiprotozoic agent
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
ES2269138T3 (es) * 1999-04-30 2007-04-01 Cellgate, Inc. Poliaminas y su uso en terapia.
US6482943B1 (en) * 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
CA2368801A1 (en) * 1999-04-30 2000-11-09 Slil Biomedical Corporation Conjugates as therapies for cancer and prostate diseases
EP1337504A4 (de) * 2000-11-08 2005-10-05 Cellgate Inc Neue polyaminanalogon-aminosäure-konjugate zur verwendung als krebsmittel
WO2003013245A1 (en) * 2001-08-07 2003-02-20 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
US7273888B2 (en) * 2001-11-16 2007-09-25 Als Therapy Development Foundation, Inc. Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
WO2003050072A1 (en) * 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
MXPA04007584A (es) * 2002-02-07 2004-12-06 Wisconsin Alumni Res Found Compuestos de poliamina y composiciones para su uso en conjunto con una terapia contra el cancer.
EP3971178A1 (de) 2012-03-07 2022-03-23 The McLean Hospital Corporation Aminochinolinderivate und verwendungen davon
CN102924390B (zh) * 2012-09-07 2014-12-31 苏州康润医药有限公司 1,5-二氮杂环辛烷-1-甲酸叔丁酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551550A (en) * 1983-12-06 1985-11-05 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butanediamine derivatives
EP0144951B1 (de) * 1983-12-06 1987-03-18 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butadiamin-Derivate
ZA88600B (en) * 1987-02-03 1988-07-28 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase

Also Published As

Publication number Publication date
HU207833B (en) 1993-06-28
CA1321603C (en) 1993-08-24
NO893135D0 (no) 1989-08-03
EP0353752B1 (de) 1994-01-05
PT91365A (pt) 1990-03-08
FI893681A0 (fi) 1989-08-03
IL91184A0 (en) 1990-03-19
AU3927189A (en) 1990-02-08
NO893135L (no) 1990-02-05
DK381189A (da) 1990-02-05
DE68912020T2 (de) 1994-04-28
JP2722255B2 (ja) 1998-03-04
EP0353752A1 (de) 1990-02-07
DK381189D0 (da) 1989-08-03
ZA895840B (en) 1990-04-25
JPH0283357A (ja) 1990-03-23
NZ230155A (en) 1991-08-27
KR900003105A (ko) 1990-03-23
KR0144155B1 (ko) 1998-07-15
FI893681A (fi) 1990-02-05
CN1039800A (zh) 1990-02-21
ATE99669T1 (de) 1994-01-15
NO172043C (no) 1993-06-02
HUT58037A (en) 1992-01-28
NO172043B (no) 1993-02-22
AU617502B2 (en) 1991-11-28
ES2061826T3 (es) 1994-12-16
US4935449A (en) 1990-06-19
PH27214A (en) 1993-05-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee