DE3682882D1 - Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung. - Google Patents

Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung.

Info

Publication number
DE3682882D1
DE3682882D1 DE8686117996T DE3682882T DE3682882D1 DE 3682882 D1 DE3682882 D1 DE 3682882D1 DE 8686117996 T DE8686117996 T DE 8686117996T DE 3682882 T DE3682882 T DE 3682882T DE 3682882 D1 DE3682882 D1 DE 3682882D1
Authority
DE
Germany
Prior art keywords
protein
region
production
human immunoglobulin
immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686117996T
Other languages
English (en)
Inventor
Satoshi Nakamura
Tsukio Masegi
Kazuo Kitai
Yataro Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of DE3682882D1 publication Critical patent/DE3682882D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
DE8686117996T 1985-12-26 1986-12-23 Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung. Expired - Lifetime DE3682882D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60292298A JPS62153300A (ja) 1985-12-26 1985-12-26 ヒト免疫グロブリンGFc領域蛋白質およびその製造方法

Publications (1)

Publication Number Publication Date
DE3682882D1 true DE3682882D1 (de) 1992-01-23

Family

ID=17779944

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686117996T Expired - Lifetime DE3682882D1 (de) 1985-12-26 1986-12-23 Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung.

Country Status (3)

Country Link
EP (1) EP0227110B1 (de)
JP (1) JPS62153300A (de)
DE (1) DE3682882D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2639231A1 (fr) * 1988-11-23 1990-05-25 Merieux Inst Utilisation de fragments fc d'immunoglobulines g humaines, de peptides analogues du fragment fc, ou d'immunoglobulines g humaines dans l'obtention d'un medicament preparatoire a l'administration chez l'homme, dans un but therapeutique ou de diagnostic, d'anticorps monoclonaux
EP1132471A3 (de) 1989-09-12 2001-11-28 F. Hoffmann-La Roche Ag TNF-bindende Proteine
AU675166B2 (en) * 1993-10-22 1997-01-23 Nihon Medi-Physics Co., Ltd. Peptide having inflammation affinity and radioactive diagnostic containing the same
KR20050047030A (ko) 2003-11-13 2005-05-19 한미약품 주식회사 약물의 캐리어로서 유용한 IgG Fc 단편 및 그의제조방법
BRPI0506771A (pt) * 2004-01-12 2007-05-22 Applied Molecular Evolution anticorpo, e, composição farmacêutica
AU2006280587B2 (en) 2005-08-16 2011-02-24 Hanmi Science Co., Ltd. A method for the mass production of immunoglobulin Fc region deleted initial methionine residues
JP2009507003A (ja) 2005-09-01 2009-02-19 アレス トレーディング ソシエテ アノニム 視神経炎の治療
WO2007135172A2 (en) 2006-05-24 2007-11-29 Laboratoires Serono S.A. Cladribine regimen for treating multiple sclerosis
EP2825557B1 (de) 2012-03-16 2017-06-28 The U.S.A. as represented by the Secretary, Department of Health and Human Services Manipuliertes lösliches monomeres fc
PT3087095T (pt) * 2013-12-24 2019-10-09 Argenx Bvba Antagonistas de fcrn e métodos de utilização
JP2022535908A (ja) 2019-06-07 2022-08-10 アルジェニクス ビーブイ 皮下投与に好適なFcRnインヒビターの医薬製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
FR2556219B1 (fr) * 1983-12-07 1987-06-26 Merieux Inst Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines
JPS61134325A (ja) * 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法

Also Published As

Publication number Publication date
EP0227110A2 (de) 1987-07-01
EP0227110B1 (de) 1991-12-11
JPS62153300A (ja) 1987-07-08
EP0227110A3 (en) 1988-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee