ZA895840B - N-2,3-butadienyl tri-and tetraaminoalkane derivatives - Google Patents

N-2,3-butadienyl tri-and tetraaminoalkane derivatives

Info

Publication number
ZA895840B
ZA895840B ZA895840A ZA895840A ZA895840B ZA 895840 B ZA895840 B ZA 895840B ZA 895840 A ZA895840 A ZA 895840A ZA 895840 A ZA895840 A ZA 895840A ZA 895840 B ZA895840 B ZA 895840B
Authority
ZA
South Africa
Prior art keywords
butadienyl
tri
tetraaminoalkane
derivatives
polyamines
Prior art date
Application number
ZA895840A
Other languages
English (en)
Inventor
Philippe Bey
Bey Philippe
David Martin Stemerick
Martin Stemerick David
Michael Louis Edwards
Louis Edwards Michael
Alan Joseph Bitonti
Joseph Bitonti Alan
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA895840B publication Critical patent/ZA895840B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21—Monoamines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/04—Nitrogen directly attached to aliphatic or cycloaliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
ZA895840A 1988-08-04 1989-07-31 N-2,3-butadienyl tri-and tetraaminoalkane derivatives ZA895840B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/228,620 US4935449A (en) 1988-08-04 1988-08-04 N-2,3-butadienyl tri- and tetraaminoalkane derivatives

Publications (1)

Publication Number Publication Date
ZA895840B true ZA895840B (en) 1990-04-25

Family

ID=22857945

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895840A ZA895840B (en) 1988-08-04 1989-07-31 N-2,3-butadienyl tri-and tetraaminoalkane derivatives

Country Status (19)

Country Link
US (1) US4935449A (de)
EP (1) EP0353752B1 (de)
JP (1) JP2722255B2 (de)
KR (1) KR0144155B1 (de)
CN (1) CN1039800A (de)
AT (1) ATE99669T1 (de)
AU (1) AU617502B2 (de)
CA (1) CA1321603C (de)
DE (1) DE68912020T2 (de)
DK (1) DK381189A (de)
ES (1) ES2061826T3 (de)
FI (1) FI893681A7 (de)
HU (1) HU207833B (de)
IL (1) IL91184A0 (de)
NO (1) NO172043C (de)
NZ (1) NZ230155A (de)
PH (1) PH27214A (de)
PT (1) PT91365A (de)
ZA (1) ZA895840B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111794D0 (en) * 1991-05-31 1991-07-24 Robins David J Antifungal compounds
WO1995018091A1 (en) * 1993-12-27 1995-07-06 Ciba-Geigy Ag Unsaturate amino compounds for use as anticancer and antiprotozoic agent
US5677350A (en) * 1995-06-07 1997-10-14 Wisconsin Alumni Research Foundation Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes
ES2269138T3 (es) 1999-04-30 2007-04-01 Cellgate, Inc. Poliaminas y su uso en terapia.
MXPA01011008A (es) * 1999-04-30 2003-06-30 Slil Biomedical Corp Conjugados analogos de poliamina y conjugados de quinona novedosos como terapia para canceres y enfermedades de la prostata.
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
AU2002235126A1 (en) * 2000-11-08 2002-05-21 Slil Biomedical Corporation Novel polyamine analog-amino acid conjugates useful as anticancer agents
WO2003013245A1 (en) * 2001-08-07 2003-02-20 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
AU2002343609B2 (en) * 2001-11-16 2008-12-11 Als Therapy Development Foundation, Inc. Treatment of neurodegenerative disorders through the modulation of the polyamine pathway
CA2469354A1 (en) * 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
JP2005517004A (ja) * 2002-02-07 2005-06-09 ウィスコンシン アルムニ リサーチ ファンデーション 癌治療に関連した使用に対するポリアミン化合物及び組成
WO2013134047A2 (en) 2012-03-07 2013-09-12 The Mclean Hospital Corporation Aminoquinoline derivatives and uses thereof
CN102924390B (zh) * 2012-09-07 2014-12-31 苏州康润医药有限公司 1,5-二氮杂环辛烷-1-甲酸叔丁酯的合成方法
US12428658B2 (en) 2019-11-25 2025-09-30 The General Hospital Corporation Methods and compositions for enzymatic polymerization of N3′→P5′ phosphoramidate DNA

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA849412B (en) * 1983-12-06 1985-07-31 Merrell Dow Pharma N-2,3-butadienyl-1,4-butanediamine derivatives
US4551550A (en) * 1983-12-06 1985-11-05 Merrell Dow Pharmaceuticals Inc. N-2,3-Butadienyl-1,4-butanediamine derivatives
CA1338764C (en) * 1987-02-03 1996-12-03 David M. Stemerick Polyamine derivatives
US5120764A (en) * 1988-11-01 1992-06-09 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase

Also Published As

Publication number Publication date
DK381189D0 (da) 1989-08-03
DE68912020D1 (de) 1994-02-17
CA1321603C (en) 1993-08-24
PH27214A (en) 1993-05-04
EP0353752B1 (de) 1994-01-05
DK381189A (da) 1990-02-05
FI893681L (fi) 1990-02-05
NZ230155A (en) 1991-08-27
HUT58037A (en) 1992-01-28
NO893135D0 (no) 1989-08-03
ES2061826T3 (es) 1994-12-16
FI893681A7 (fi) 1990-02-05
AU617502B2 (en) 1991-11-28
NO172043C (no) 1993-06-02
KR0144155B1 (ko) 1998-07-15
FI893681A0 (fi) 1989-08-03
NO172043B (no) 1993-02-22
NO893135L (no) 1990-02-05
JP2722255B2 (ja) 1998-03-04
IL91184A0 (en) 1990-03-19
JPH0283357A (ja) 1990-03-23
PT91365A (pt) 1990-03-08
KR900003105A (ko) 1990-03-23
EP0353752A1 (de) 1990-02-07
DE68912020T2 (de) 1994-04-28
ATE99669T1 (de) 1994-01-15
CN1039800A (zh) 1990-02-21
US4935449A (en) 1990-06-19
HU207833B (en) 1993-06-28
AU3927189A (en) 1990-02-08

Similar Documents

Publication Publication Date Title
AU586860B2 (en) Therapeutical application of phosphonylmethoxyalkyl adenines
AU1466388A (en) Low molecular weight heparins of regular structure, their preparation and their biological uses
DE3883985D1 (de) Ärztliches instrument und dessen herstellung.
ZA895840B (en) N-2,3-butadienyl tri-and tetraaminoalkane derivatives
AU6780687A (en) Benzamido-aromatic derivatives, process for their preparation and their use in human or veterinary medicine and in cosmetics
EP0400958A3 (de) Lebende Impfstoffe
AU579696B2 (en) Disposable, underpants, such as child's training pants and the like
DE3682882D1 (de) Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung.
AU1384995A (en) Human circulating cytokine cc-1
CA2094275A1 (en) Methods and compositions for the treatment of cell proliferation disorders
BG50159A3 (bg) Метод за получаване на производни на пиранобензоксадиазол
AU6920387A (en) Molecular probes, process for preparation thereof, and applications including their use for determining the sex of embryos
EP0246223A4 (de) Produktionssteigerungs- und stimulierungsmittel für mikrobielle pflanzen.
ES2016464A6 (es) Procedimiento para preparar derivados de 2', 5' -oligoadenilato.
AU5668286A (en) Carbohydrate derivatives and compositions thereof for therapeutic or diagnostic use, and methods for their use
FR2651230B1 (fr) Derives de la 5-amino-1,2,3,4 tetrahydro-acridine et applications comme medicaments.
IT8519907A0 (it) Prodotto farmaceutico cosmetico, in particolare per la cura di acne e seborrea.
AU6877587A (en) Expellants of phytopathogenic microbes
AU8082687A (en) 2,6-diamino-3-halobenzylpyridines and processes for their manufacture as well as their use in pharmaceuticals
KR900700484A (ko) 1,4:3,6-디안히드로 헥시톨 잘산염의 아미노프로판올 유도체,그의 제법 및 약제로서의 그의 용도
MY103584A (en) 8(alpha)-acylaminoergoline, its preparation and pharmaceutical compositions containing it
AU7111587A (en) Perhydrothiazepine and perhydroazepine derivatives,their preparation and their therapeutic use
NO890261D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive tetrahydropyridin-derivater.
FR2632861B1 (fr) Derives d'amino-4 carboxy-3 quinoleines et naphtyridines, leur procede de preparation et leur application comme medicaments
GR1002969B (el) Φαρμακευτικο παρασκευασμα βασιζομενο σε αιωρημα εμβρυικων κυτταρων με δραση ανοσοποιητικης υποκαταστασης και μεθοδος θεραπειας του συνδρομου της επικτητης μολυνσης ανοσοποιητικης ανεπαρκειας (hiv) με τη χρηση αυτου του παρασκευασματος.