FI883261L - Menetelmä somatostatiinia sisältävän farmaseuttisen ainekoostumuksen valmistamiseksi - Google Patents

Menetelmä somatostatiinia sisältävän farmaseuttisen ainekoostumuksen valmistamiseksi Download PDF

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Publication number
FI883261L
FI883261L FI883261A FI883261A FI883261L FI 883261 L FI883261 L FI 883261L FI 883261 A FI883261 A FI 883261A FI 883261 A FI883261 A FI 883261A FI 883261 L FI883261 L FI 883261L
Authority
FI
Finland
Prior art keywords
preparing
pharmaceutical composition
composition containing
containing somatostatin
somatostatin
Prior art date
Application number
FI883261A
Other languages
English (en)
Swedish (sv)
Other versions
FI93308C (fi
FI93308B (fi
FI883261A0 (fi
Inventor
Thomas Cavanak
Alan Harris
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878716326A external-priority patent/GB8716326D0/en
Priority claimed from GB878716324A external-priority patent/GB8716324D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI883261A0 publication Critical patent/FI883261A0/fi
Publication of FI883261L publication Critical patent/FI883261L/fi
Application granted granted Critical
Publication of FI93308B publication Critical patent/FI93308B/fi
Publication of FI93308C publication Critical patent/FI93308C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
FI883261A 1987-07-10 1988-07-08 Menetelmä somatostatiinia sisältävän farmaseuttisen ainekoostumuksen valmistamiseksi FI93308C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB878716326A GB8716326D0 (en) 1987-07-10 1987-07-10 Organic compounds
GB878716324A GB8716324D0 (en) 1987-07-10 1987-07-10 Organic compounds
GB8716326 1987-07-10
GB8716324 1987-07-10

Publications (4)

Publication Number Publication Date
FI883261A0 FI883261A0 (fi) 1988-07-08
FI883261L true FI883261L (fi) 1989-01-11
FI93308B FI93308B (fi) 1994-12-15
FI93308C FI93308C (fi) 1995-03-27

Family

ID=26292476

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883261A FI93308C (fi) 1987-07-10 1988-07-08 Menetelmä somatostatiinia sisältävän farmaseuttisen ainekoostumuksen valmistamiseksi

Country Status (27)

Country Link
US (2) US5753618A (fi)
JP (1) JP2578477B2 (fi)
AU (1) AU618270B2 (fi)
BE (1) BE1001079A4 (fi)
CA (1) CA1328402C (fi)
CH (1) CH677449A5 (fi)
CS (1) CS411591A3 (fi)
CY (2) CY1632A (fi)
DE (2) DE3822557C2 (fi)
DK (2) DK174125B1 (fi)
ES (1) ES2010561A6 (fi)
FI (1) FI93308C (fi)
FR (1) FR2617714B1 (fi)
GB (1) GB2208200B (fi)
GR (1) GR1000172B (fi)
HK (1) HK16492A (fi)
HU (1) HU203480B (fi)
IE (1) IE61908B1 (fi)
IL (1) IL87044A0 (fi)
LU (1) LU87268A1 (fi)
MY (2) MY103746A (fi)
NL (1) NL194823C (fi)
NO (1) NO179359C (fi)
NZ (1) NZ225340A (fi)
PT (1) PT87957B (fi)
SE (2) SE503191C2 (fi)
SG (1) SG3692G (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
PH30995A (en) * 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
RU2128055C1 (ru) * 1992-12-07 1999-03-27 Такеда Кемикал Индастриз Лтд. Фармацевтическая композиция замедленного высвобождения и способ ее получения
US5626945A (en) * 1993-09-28 1997-05-06 International Paper Company Repulpable, water repellant paperboard
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
WO1998008528A1 (en) 1996-08-30 1998-03-05 Biomeasure Incorporated Method of inhibiting fibrosis with a somatostatin agonist
ES2167189B1 (es) * 1999-12-17 2003-04-01 Lipotec Sa Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
US6316414B1 (en) 2000-07-31 2001-11-13 Dabur Research Foundation Somatostatin analogs for the treatment of cancer
CN101481405A (zh) * 2001-06-08 2009-07-15 研究及应用科学协会股份有限公司 生长激素释放抑制因子-多巴胺嵌合类似物
TWI287986B (en) * 2001-12-13 2007-10-11 Novartis Ag Use of Epothilones for the treatment of the carcinoid syndrome
US20030207811A1 (en) * 2002-05-03 2003-11-06 Schrier Bruce K. Method of treating retinopathy of prematurity using somatostatin analogs
PE20050285A1 (es) * 2003-06-24 2005-06-09 Novartis Ag Composicion farmaceutica que comprende analogos ciclicos de somatostatina
GB0428151D0 (en) * 2004-12-22 2005-01-26 Novartis Ag Organic compounds
ATE549011T1 (de) 2005-11-10 2012-03-15 Chemi Spa Formulierungen mit verzögerter freisetzung, die somatostatin-analoge wachstumshormoninhibitoren enthalten
CA2647986C (en) * 2006-03-31 2014-07-08 Erasmus University Medical Center Rotterdam Compositions for tumor growth control
US9517240B2 (en) 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
WO2008039482A2 (en) * 2006-09-26 2008-04-03 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20090325863A1 (en) * 2008-06-13 2009-12-31 Kleinberg David L Somatostatin analogs and IGF-I inhibition for breast cancer prevention
GB201016433D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Apparatus and method for making solid beads
GB201016436D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Method of making solid beads
WO2012074559A2 (en) * 2010-12-02 2012-06-07 New York University Treatment of non-proliferative cystic disease
CN109248310B (zh) * 2011-06-02 2022-07-01 加利福尼亚大学董事会 利用θ-防御素的炎性蛋白酶的阻断
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
CN104768565B (zh) 2012-11-01 2017-04-26 益普生制药股份有限公司 促生长素抑制素类似物及其二聚体

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH621770A5 (en) * 1976-02-23 1981-02-27 Sandoz Ag Process for the preparation of novel peptide compounds
IT1105131B (it) * 1977-06-08 1985-10-28 Merck & Co Inc Peptidi analoghi della somatostatina dotati di piu' lunga e maggiore attivita' biologica e relativo procedimento di protezione
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4328214A (en) * 1979-07-04 1982-05-04 Ciba-Geigy Corporation Cyclopeptides and pharmaceutical preparations thereof and also processes for their manufacture
US4900730A (en) * 1981-01-14 1990-02-13 Toyo Jozo Co., Ltd. Preparation which promotes the absorption of peptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
US4374060A (en) * 1981-07-15 1983-02-15 Merck & Co., Inc. Process for the preparation of cyclic hexapeptide
DE3264693D1 (en) * 1981-12-24 1985-08-14 Ciba Geigy Ag Cyclic octapeptides and pharmaceutical compositions thereof, and processes for their production and use
US4522813A (en) * 1983-10-27 1985-06-11 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
JPH085913B2 (ja) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド 治療用ソマトスタチン同族体
HU198626B (en) * 1986-05-27 1989-11-28 Sandoz Ag Process for producing pharmaceutical compositions comprising somatostatin analogues as active ingredient
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
US5187150A (en) * 1987-10-14 1993-02-16 Debiopharm S.A. Polyester-based composition for the controlled release of polypeptide medicinal substances
AU2284588A (en) * 1988-09-26 1990-03-29 Sandoz Ltd. Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体

Also Published As

Publication number Publication date
PT87957A (pt) 1989-06-30
PT87957B (pt) 1995-03-01
FR2617714B1 (fr) 1991-09-20
CA1328402C (en) 1994-04-12
FI93308C (fi) 1995-03-27
JPS6431728A (en) 1989-02-02
HUT47865A (en) 1989-04-28
FI93308B (fi) 1994-12-15
DE3845000C2 (de) 1998-11-19
NO883054D0 (no) 1988-07-08
NL8801734A (nl) 1989-02-01
DK385488D0 (da) 1988-07-08
JP2764041B2 (ja) 1998-06-11
SE8802569D0 (sv) 1988-07-08
FR2617714A1 (fr) 1989-01-13
NZ225340A (en) 1991-05-28
DK200100558A (da) 2001-04-04
GB2208200A (en) 1989-03-15
ES2010561A6 (es) 1989-11-16
US6066616A (en) 2000-05-23
SE9301290A0 (sv) 1993-04-20
BE1001079A4 (fr) 1989-07-04
US5753618A (en) 1998-05-19
NL194823B (nl) 2002-12-02
CY1631A (en) 1992-07-10
GB2208200B (en) 1991-11-27
DE3822557A1 (de) 1989-01-19
LU87268A1 (fr) 1989-03-08
HK16492A (en) 1992-03-06
MY103746A (en) 1993-09-30
NO883054L (no) 1989-01-11
SE503191C2 (sv) 1996-04-15
SE8802569L (sv) 1989-01-11
NO179359B (no) 1996-06-17
CH677449A5 (fi) 1991-05-31
NL194823C (nl) 2003-04-03
IE882091L (en) 1989-01-10
AU1889388A (en) 1989-01-12
IE61908B1 (en) 1994-11-30
DE3822557C2 (de) 1998-07-02
GR880100458A (en) 1989-04-12
DK174476B1 (da) 2003-04-14
FI883261A0 (fi) 1988-07-08
GB8816024D0 (en) 1988-08-10
AU618270B2 (en) 1991-12-19
CS411591A3 (en) 1992-06-17
NO179359C (no) 1996-09-25
SG3692G (en) 1992-03-20
CY1632A (en) 1992-07-10
GR1000172B (el) 1991-11-15
HU203480B (en) 1991-08-28
JP2578477B2 (ja) 1997-02-05
IL87044A0 (en) 1988-12-30
DK385488A (da) 1989-01-11
DK174125B1 (da) 2002-07-01
JPH0748272A (ja) 1995-02-21
SE9301290D0 (sv) 1993-04-20
MY109309A (en) 1997-01-31

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG