EE04676B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Info

Publication number
EE04676B1
EE04676B1 EEP200000626A EEP200000626A EE04676B1 EE 04676 B1 EE04676 B1 EE 04676B1 EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 04676 B1 EE04676 B1 EE 04676B1
Authority
EE
Estonia
Prior art keywords
imidazopidine
derivatives
preparation
gastric acid
acid secretion
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Estonian (et)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/xx
Publication of EE04676B1 publication Critical patent/EE04676B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A EE200000626A (et) 2002-04-15
EE04676B1 true EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (34)

Country Link
US (2) US6313136B1 (no)
EP (4) EP1491542B1 (no)
JP (2) JP3692034B2 (no)
KR (3) KR100595805B1 (no)
CN (2) CN1174980C (no)
AR (2) AR015769A1 (no)
AT (4) ATE312101T1 (no)
AU (2) AU769108B2 (no)
BR (2) BR9909995B1 (no)
CA (2) CA2329922C (no)
CZ (2) CZ293977B6 (no)
DE (4) DE69927803T2 (no)
DK (2) DK1073656T3 (no)
EE (2) EE04916B1 (no)
ES (2) ES2252975T3 (no)
HK (5) HK1033457A1 (no)
HU (2) HUP0102313A3 (no)
ID (2) ID26819A (no)
IL (4) IL139297A0 (no)
IS (2) IS5684A (no)
MY (2) MY121379A (no)
NO (2) NO317262B1 (no)
NZ (2) NZ507639A (no)
PL (2) PL195000B1 (no)
RU (2) RU2238271C2 (no)
SA (2) SA99200064B1 (no)
SE (1) SE9801526D0 (no)
SI (1) SI1073656T1 (no)
SK (2) SK14912000A3 (no)
TR (4) TR200102612T2 (no)
TW (2) TW490466B (no)
UA (2) UA66846C2 (no)
WO (2) WO1999055705A1 (no)
ZA (2) ZA200005797B (no)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
ES2261643T3 (es) * 2001-02-13 2006-11-16 Astrazeneca Ab Nueva formulacion de liberacion modificada.
CN1496259A (zh) * 2001-03-08 2004-05-12 新用途
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
AR041291A1 (es) 2002-09-19 2005-05-11 Schering Corp Imidazopiridinas como inhibidores de quinasa dependientes de ciclina
EP1565465A1 (en) 2002-11-19 2005-08-24 ALTANA Pharma AG 8-substituted imidazopyridines
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
DK2476667T3 (da) * 2003-02-26 2014-09-15 Sugen Inc Aminoheteroaryl-forbindelser som proteinkinase-inhibitorer
RS52908B (en) 2003-03-10 2014-02-28 Takeda Gmbh NEW PROCEDURE FOR OBTAINING ROFLUMILAST
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2544325A1 (en) 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
EP1711498A2 (en) * 2004-01-26 2006-10-18 Altana Pharma AG 1,2,4-triazolo¬1,5-a|pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
ES2313444T3 (es) * 2004-12-17 2009-03-01 Raqualia Pharma Inc Derivados de cromano utiles como antagonistas de la bomba de acido.
ES2421916T3 (es) 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
AR056187A1 (es) * 2005-03-21 2007-09-26 S Bio Pte Ltd Derivados de imidazo[1,2-a)piridina: preparacion, composiciones farmaceuticas y uso para preparar medicamentos
WO2006100119A1 (en) * 2005-03-24 2006-09-28 Glaxo Group Limited Derivatives of imidazo (1,2-a) pyridine useful as medicaments for treating gastrointestinal diseases
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
SI1963302T1 (sl) * 2005-12-05 2013-04-30 Pfizer Products Inc. Polimorfne oblike inhibitorja c-met/hgfr
ATE488237T1 (de) * 2005-12-05 2010-12-15 Pfizer Prod Inc Verfahren zur behandlung von abnormalem zellwachstum
CA2645007A1 (en) * 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
JP5571380B2 (ja) 2006-07-24 2014-08-13 ルミナス バイオサイエンシズ，インコーポレイテッド オストワルド熟成を減少させた水不溶性の医薬品物質の固体ナノ粒子処方物
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
US8513226B2 (en) * 2008-03-31 2013-08-20 Council Of Scientific And Industrial Research Simultaneous method for the preparation of a mixture of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3-acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
KR101605063B1 (ko) * 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
RU2673542C2 (ru) * 2013-06-25 2018-11-28 Ф. Хоффманн-Ля Рош Аг Соединения для лечения спинальной мышечной атрофии
JP6616772B2 (ja) 2013-12-16 2019-12-04 アサナ・バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー Ｐ２ｘ３および／またはｐ２ｘ２／３化合物ならびに方法
US9464083B2 (en) * 2014-03-24 2016-10-11 Arqule Inc. Process of preparing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-B]pyridin-2-yl)pyridin-2-amine
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
EP3749697A4 (en) 2018-02-05 2021-11-03 Bio-Rad Laboratories, Inc. CHROMATOGRAPHIC RESIN WITH A LIGAND WITH ANION EXCHANGE-HYDROPHOBIC MIXED MODE
JP7353295B2 (ja) * 2018-04-10 2023-09-29 バイエル・アクチエンゲゼルシヤフト ２，６－ジアルキルフェニル酢酸の製造方法
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
EP4054537B1 (en) 2019-11-04 2023-06-07 Cinclus Pharma Holding AB (publ) Oral formulation of x842
AU2022381536A1 (en) 2021-11-05 2024-05-02 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrochloride salt of linaprazan glurate
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
CZ20003982A3 (cs) 2001-02-14
JP3692034B2 (ja) 2005-09-07
ES2252975T3 (es) 2006-05-16
WO1999055706A9 (en) 2000-03-16
DE69937076D1 (de) 2007-10-18
NO20005450L (no) 2000-12-22
EP1491543A1 (en) 2004-12-29
HUP0102425A2 (hu) 2001-11-28
AU4300799A (en) 1999-11-16
TWI250159B (en) 2006-03-01
IL139297A (en) 2007-06-03
SK14922000A3 (sk) 2001-06-11
NO20005451L (no) 2000-12-27
SA99200065B1 (ar) 2006-11-07
EP1073656B1 (en) 2005-10-19
KR20050121760A (ko) 2005-12-27
ID26819A (id) 2001-02-15
JP3883383B2 (ja) 2007-02-21
ATE372339T1 (de) 2007-09-15
DE69937077T2 (de) 2008-05-29
HK1033457A1 (en) 2001-08-31
ATE312101T1 (de) 2005-12-15
SA99200065A (ar) 2005-12-03
TR200003176T2 (tr) 2001-03-21
TW490466B (en) 2002-06-11
MY121389A (en) 2006-01-28
NZ507639A (en) 2004-01-30
CZ292567B6 (cs) 2003-10-15
CZ20003981A3 (cs) 2001-03-14
EP1491543B1 (en) 2007-09-05
TR200102612T2 (tr) 2002-06-21
HK1036981A1 (en) 2002-01-25
JP2002513024A (ja) 2002-05-08
SE9801526D0 (sv) 1998-04-29
EP1491542A2 (en) 2004-12-29
DE69928792D1 (de) 2006-01-12
CA2329921A1 (en) 1999-11-04
AU769190B2 (en) 2004-01-22
ZA200005797B (en) 2002-01-18
ATE372340T1 (de) 2007-09-15
AR015768A1 (es) 2001-05-16
SK285768B6 (sk) 2007-07-06
NO317262B1 (no) 2004-09-27
RU2238271C2 (ru) 2004-10-20
DE69937076T2 (de) 2008-05-29
IL139297A0 (en) 2001-11-25
US6313137B1 (en) 2001-11-06
RU2235725C2 (ru) 2004-09-10
ATE307130T1 (de) 2005-11-15
JP2002513025A (ja) 2002-05-08
EE200000626A (et) 2002-04-15
HUP0102313A3 (en) 2002-10-28
EP1073656A1 (en) 2001-02-07
BR9909996A (pt) 2000-12-26
HUP0102425A3 (en) 2002-12-28
CA2329922C (en) 2006-04-11
MY121379A (en) 2006-01-28
AU4300699A (en) 1999-11-16
CN1165535C (zh) 2004-09-08
DK1073656T3 (da) 2006-01-16
WO1999055705A1 (en) 1999-11-04
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
TR200003149T2 (tr) 2001-03-21
NZ507638A (en) 2003-10-31
EE04916B1 (et) 2007-10-15
HUP0102313A2 (hu) 2001-12-28
CN1174980C (zh) 2004-11-10
UA67769C2 (uk) 2004-07-15
AU769108B2 (en) 2004-01-15
KR20010043134A (ko) 2001-05-25
PL195000B1 (pl) 2007-07-31
SA99200064B1 (ar) 2006-10-11
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
EP1073657A1 (en) 2001-02-07
ES2249913T3 (es) 2006-04-01
PL343797A1 (en) 2001-09-10
IS5683A (is) 2000-10-25
CN1307577A (zh) 2001-08-08
ZA200005796B (en) 2002-01-18
CA2329922A1 (en) 1999-11-04
CZ293977B6 (cs) 2004-09-15
US6313136B1 (en) 2001-11-06
BR9909995A (pt) 2000-12-26
HK1036984A1 (en) 2002-01-25
KR100595805B1 (ko) 2006-07-03
HK1071139A1 (en) 2005-07-08
TR200102728T2 (tr) 2002-06-21
DK1073657T3 (da) 2006-03-13
KR100650472B1 (ko) 2006-11-28
DE69928792T2 (de) 2006-07-20
PL343801A1 (en) 2001-09-10
KR100595806B1 (ko) 2006-07-03
AR015769A1 (es) 2001-05-16
BR9909995B1 (pt) 2010-07-13
ID27530A (id) 2001-04-12
EP1073657B1 (en) 2005-12-07
IS5684A (is) 2000-10-25
NO318203B1 (no) 2005-02-14
SK14912000A3 (sk) 2001-06-11
EP1491542A3 (en) 2005-01-05
IL139200A (en) 2010-04-29
HK1033317A1 (en) 2001-08-24
CN1306533A (zh) 2001-08-01
BR9909996B1 (pt) 2010-08-24
DE69927803D1 (de) 2006-03-02
IL139200A0 (en) 2001-11-25
NO20005451D0 (no) 2000-10-27
NO20005450D0 (no) 2000-10-27
KR20010043133A (ko) 2001-05-25
DE69937077D1 (de) 2007-10-18
UA66846C2 (uk) 2004-06-15
DE69927803T2 (de) 2006-07-06

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