EE02958B1 - Prolongeeritud toimega preparaat, polümeeride segu selle valmistamiseks ja polümeeride segu valmistamismeetod - Google Patents

Prolongeeritud toimega preparaat, polümeeride segu selle valmistamiseks ja polümeeride segu valmistamismeetod

Info

Publication number
EE02958B1
EE02958B1 EE9400413A EE9400413A EE02958B1 EE 02958 B1 EE02958 B1 EE 02958B1 EE 9400413 A EE9400413 A EE 9400413A EE 9400413 A EE9400413 A EE 9400413A EE 02958 B1 EE02958 B1 EE 02958B1
Authority
EE
Estonia
Prior art keywords
preparation
polymer blend
prolonged
release
drug
Prior art date
Application number
EE9400413A
Other languages
English (en)
Estonian (et)
Inventor
Yamada Minoru
Ishiguro Seiko
Ogawa Yasuaki
Original Assignee
Takeda Chemical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries, Ltd. filed Critical Takeda Chemical Industries, Ltd.
Publication of EE02958B1 publication Critical patent/EE02958B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/745Polymers of hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04Polyesters derived from hydroxycarboxylic acids, e.g. lactones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EE9400413A 1990-10-16 1994-11-17 Prolongeeritud toimega preparaat, polümeeride segu selle valmistamiseks ja polümeeride segu valmistamismeetod EE02958B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27803790 1990-10-16
JP21704591 1991-08-28

Publications (1)

Publication Number Publication Date
EE02958B1 true EE02958B1 (et) 1997-02-17

Family

ID=26521778

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9400413A EE02958B1 (et) 1990-10-16 1994-11-17 Prolongeeritud toimega preparaat, polümeeride segu selle valmistamiseks ja polümeeride segu valmistamismeetod

Country Status (24)

Country Link
US (1) US5304377A (es)
EP (1) EP0481732B1 (es)
JP (1) JP3196035B2 (es)
KR (1) KR100199119B1 (es)
CN (2) CN1043189C (es)
AT (1) ATE119035T1 (es)
AU (1) AU644019B2 (es)
CA (1) CA2053468C (es)
DE (1) DE69107773T2 (es)
DK (1) DK0481732T3 (es)
EE (1) EE02958B1 (es)
ES (1) ES2069221T3 (es)
FI (1) FI101454B1 (es)
GE (1) GEP19981287B (es)
IE (1) IE66705B1 (es)
LT (1) LT3277B (es)
LV (1) LV10055B (es)
MX (1) MX9101595A (es)
NO (1) NO302481B1 (es)
NZ (1) NZ240214A (es)
PT (1) PT99236B (es)
RU (1) RU2103005C1 (es)
UA (1) UA27707C2 (es)
ZA (1) ZA918168B (es)

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Publication number Publication date
ZA918168B (en) 1993-04-14
US5304377A (en) 1994-04-19
UA27707C2 (uk) 2000-10-16
NO914032L (no) 1992-04-21
ES2069221T3 (es) 1995-05-01
CN1043189C (zh) 1999-05-05
IE913624A1 (en) 1992-04-22
KR100199119B1 (ko) 1999-06-15
CA2053468A1 (en) 1992-04-17
MX9101595A (es) 1992-06-05
EP0481732B1 (en) 1995-03-01
PT99236B (pt) 1999-04-30
FI101454B (fi) 1998-06-30
CN1057670C (zh) 2000-10-25
NO914032D0 (no) 1991-10-14
DE69107773T2 (de) 1995-06-29
DK0481732T3 (da) 1995-05-22
FI101454B1 (fi) 1998-06-30
FI914865A0 (fi) 1991-10-15
JPH05112468A (ja) 1993-05-07
IE66705B1 (en) 1996-01-24
RU2103005C1 (ru) 1998-01-27
AU8586491A (en) 1992-04-30
LTIP442A (en) 1994-11-25
NZ240214A (en) 1993-02-25
ATE119035T1 (de) 1995-03-15
EP0481732A1 (en) 1992-04-22
DE69107773D1 (de) 1995-04-06
FI914865A (fi) 1992-04-17
CN1060851A (zh) 1992-05-06
GEP19981287B (en) 1998-09-01
PT99236A (pt) 1992-09-30
AU644019B2 (en) 1993-12-02
CA2053468C (en) 2002-07-09
CN1116212A (zh) 1996-02-07
LV10055B (en) 1995-02-20
KR920007632A (ko) 1992-05-27
NO302481B1 (no) 1998-03-09
LT3277B (en) 1995-05-25
JP3196035B2 (ja) 2001-08-06
LV10055A (lv) 1994-05-10

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