US4783443A
(en)
|
1986-03-03 |
1988-11-08 |
The University Of Chicago |
Amino acyl cephalosporin derivatives
|
US5844092A
(en)
|
1994-03-18 |
1998-12-01 |
Genentech, Inc. |
Human TRK receptors and neurotrophic factor inhibitors
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
EP0914339B1
(en)
|
1996-05-08 |
2006-08-02 |
Biogen Idec MA Inc. |
RET LIGAND 3 (RetL3) FOR STIMULATING NEURAL AND RENAL GROWTH
|
US6677135B1
(en)
|
1996-05-08 |
2004-01-13 |
Biogen, Inc. |
Ret ligand (RetL) for stimulating neutral and renal growth
|
US6682921B1
(en)
|
1996-08-21 |
2004-01-27 |
New York University |
Crystals of the tyrosine kinase domain of non-insulin receptor tyrosine kinases
|
US6531152B1
(en)
|
1998-09-30 |
2003-03-11 |
Dexcel Pharma Technologies Ltd. |
Immediate release gastrointestinal drug delivery system
|
AU7103900A
(en)
|
1999-09-01 |
2001-03-26 |
Biogen, Inc. |
Ret ligand 5 (retl5) compositions and uses thereof
|
FI20000403A0
(fi)
|
2000-02-22 |
2000-02-22 |
Hannu Sariola |
GDNF perhesukuisten yhdisteiden käyttö kivessyövän hoitoon tarkoitettujen tuotteiden valmistamiseksi
|
AU7142201A
(en)
|
2000-06-22 |
2002-01-02 |
Genentech Inc |
Agonist anti-trk-c monoclonal antibodies
|
AU2002334355A1
(en)
|
2001-09-06 |
2003-03-18 |
Prochon Biotech Ltd. |
Protein tyrosine kinase inhibitors
|
US7466344B2
(en)
|
2002-06-07 |
2008-12-16 |
Scimeasure Analytical Systems, Inc. |
High-speed low noise CCD controller
|
ITMI20021620A1
(it)
|
2002-07-23 |
2004-01-23 |
Novuspharma Spa |
Composto ad ativita' antitumorale
|
CA2493000A1
(en)
|
2002-07-24 |
2004-01-29 |
University Of Cincinnati |
4-4(methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide for treating mutated-ret kinase associated diseases
|
ES2325440T3
(es)
|
2003-02-20 |
2009-09-04 |
Smithkline Beecham Corporation |
Compuestos de pirimidina.
|
JP2005106669A
(ja)
|
2003-09-30 |
2005-04-21 |
Olympus Corp |
生体関連物質の反応・測定システム
|
US20090143399A1
(en)
|
2003-10-14 |
2009-06-04 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein Kinase Inhibitors
|
US7169918B2
(en)
|
2003-10-27 |
2007-01-30 |
Genelabs Technologies, Inc. |
Methods for preparing 7-(2′-substituted-β-D-ribofuranosyl)-4-(NR2R3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives
|
MY141220A
(en)
|
2003-11-17 |
2010-03-31 |
Astrazeneca Ab |
Pyrazole derivatives as inhibitors of receptor tyrosine kinases
|
AU2004295061B2
(en)
|
2003-11-21 |
2008-11-20 |
Novartis Ag |
1H-imidazoquinoline derivatives as protein kinase inhibitors
|
KR20060110307A
(ko)
|
2003-11-28 |
2006-10-24 |
노파르티스 아게 |
단백질 키나아제 의존성 질환의 치료에서의 디아릴 우레아유도체
|
CA2550361C
(en)
|
2003-12-19 |
2014-04-29 |
Prabha Ibrahim |
Compounds and methods for development of ret modulators
|
GB0330042D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions them
|
GB0330043D0
(en)
|
2003-12-24 |
2004-01-28 |
Pharmacia Italia Spa |
Pyrrolo [2,3-b] pyridine derivatives active as kinase inhibitors process for their preparation and pharmaceutical compositions comprising them
|
WO2005068424A1
(en)
|
2004-01-20 |
2005-07-28 |
Cell Therapeutics Europe S.R.L. |
Indolinone derivatives as receptor tyrosine kinase ihibitors
|
PE20051089A1
(es)
|
2004-01-22 |
2006-01-25 |
Novartis Ag |
Derivados de pirazolo [1,5-a] pirimidin-7-il-amina como inhibidores de quinasa de proteina
|
US20050222171A1
(en)
|
2004-01-22 |
2005-10-06 |
Guido Bold |
Organic compounds
|
WO2005099363A2
(en)
|
2004-03-26 |
2005-10-27 |
Whitehead Institute For Biomedical Research |
Methods of diagnosing, preventing and treating cancer metastasis
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
BRPI0514094A
(pt)
|
2004-08-02 |
2008-05-27 |
Osi Pharm Inc |
composto, composição, e, método de tratamento de distúrbio hiperproliferativo
|
PE20060664A1
(es)
|
2004-09-15 |
2006-08-04 |
Novartis Ag |
Amidas biciclicas como inhibidores de cinasa
|
WO2006050076A1
(en)
|
2004-10-29 |
2006-05-11 |
Janssen Pharmaceutica, N.V. |
Pyrimidinyl substituted fused-pyrrolyl compounds useful in treating kinase disorders
|
DE102005003687A1
(de)
|
2005-01-26 |
2006-07-27 |
Sphingo Tec Gmbh |
Immunoassay zur Bestimmung der Freisetzung von Neurotensin in die Zirkulation
|
GB0501999D0
(en)
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
CN101257948A
(zh)
|
2005-02-18 |
2008-09-03 |
阿特努奥恩公司 |
嘧啶并二氮䓬衍生物及吲哚并蝶啶化合物
|
GB0507575D0
(en)
|
2005-04-14 |
2005-05-18 |
Novartis Ag |
Organic compounds
|
WO2006113509A2
(en)
|
2005-04-15 |
2006-10-26 |
Cylene Pharmaceuticals, Inc. |
Quinobenzoxazine analogs and methods of using thereof
|
AU2006248780B2
(en)
|
2005-05-16 |
2010-06-03 |
Astrazeneca Ab |
Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors
|
WO2006128042A2
(en)
|
2005-05-26 |
2006-11-30 |
The Johns Hopkins University |
Methods of identifying mutations in nucleic acid
|
US7541367B2
(en)
|
2005-05-31 |
2009-06-02 |
Janssen Pharmaceutica, N.V. |
3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders
|
WO2006130613A2
(en)
|
2005-05-31 |
2006-12-07 |
The Pfahl Family Trust (Dated 9 July 1996) |
Substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases
|
ITRM20050290A1
(it)
|
2005-06-07 |
2006-12-08 |
Lay Line Genomics Spa |
Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
|
BRPI0611863B1
(pt)
|
2005-06-22 |
2021-11-23 |
Plexxikon, Inc |
Composto, bem como composição e kit compreendendo o mesmo, composto intermediário na preparação do mesmo, método para tratamento e uso do mesmo
|
GB0515026D0
(en)
|
2005-07-21 |
2005-08-31 |
Novartis Ag |
Organic compounds
|
MX2008002524A
(es)
|
2005-08-25 |
2008-03-14 |
Creabilis Therapeutics Spa |
Conjugados polimericos de k-252a y sus derivados.
|
WO2007053776A1
(en)
|
2005-11-03 |
2007-05-10 |
Sgx Pharmaceuticals, Inc. |
Pyrimidinyl-thiophene kinase modulators
|
EP1785420A1
(en)
|
2005-11-14 |
2007-05-16 |
4Sc Ag |
Thiazole analogues and uses thereof
|
US20070149523A1
(en)
|
2005-11-14 |
2007-06-28 |
Jan Ehlert |
Thiazole Analogues and Uses Thereof
|
WO2007057397A1
(en)
|
2005-11-15 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Treatment of cancer
|
WO2007057399A2
(en)
|
2005-11-15 |
2007-05-24 |
Boehringer Ingelheim International Gmbh |
Treatment of cancer with indole derivatives
|
GB0524436D0
(en)
|
2005-11-30 |
2006-01-11 |
Novartis Ag |
Organic compounds
|
US7795273B2
(en)
|
2005-12-08 |
2010-09-14 |
Novartis Ag |
Pyrazolo[1,5-a]pyridine-3-carboxylic acids as EphB and VEGFR2 kinase inhibitors
|
EP1968579A1
(en)
|
2005-12-30 |
2008-09-17 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
EP1978958A4
(en)
|
2006-01-24 |
2009-12-02 |
Merck & Co Inc |
INHIBITION OF TYROSINE KINASE RET
|
PT1973910E
(pt)
|
2006-01-27 |
2013-09-06 |
Shanghai Hengrui Pharm Co Ltd |
Inibidores de pirrolo [3,2-c] piridina-4-ona 2-indolinona proteína cinase
|
BRPI0710181A2
(pt)
|
2006-03-16 |
2011-08-09 |
Novartis Ag |
compostos orgánicos
|
NZ571566A
(en)
|
2006-03-17 |
2011-07-29 |
Ambit Biosciences Corp |
Imidazolothiazole compounds for the treatment of disease
|
MX2008012422A
(es)
|
2006-03-27 |
2008-10-09 |
Nerviano Medical Sciences Srl |
Derivados de furano y tiofeno, pirrol substituido con pirimidinil y piridil como inhibidores de cinasa.
|
AU2007254491A1
(en)
|
2006-05-15 |
2007-11-29 |
Irm Llc |
Compositions and methods for FGF receptor kinases inhibitors
|
EP2036557B1
(en)
|
2006-05-18 |
2015-10-21 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
US8063225B2
(en)
|
2006-08-14 |
2011-11-22 |
Chembridge Corporation |
Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
|
US20110195072A1
(en)
|
2006-09-12 |
2011-08-11 |
Anne Boulay |
Non-neuroendocrine cancer therapy
|
CN101553482B
(zh)
|
2006-09-15 |
2013-11-20 |
艾科睿制药公司 |
激酶抑制剂化合物
|
US20120225057A1
(en)
|
2006-10-11 |
2012-09-06 |
Deciphera Pharmaceuticals, Llc |
Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
|
EP1918291A1
(en)
|
2006-10-30 |
2008-05-07 |
Novartis AG |
3-Aminocarbonyl-substituted fused pyrazolo-derivatives as protein kinase modulators
|
DK2848610T3
(da)
|
2006-11-15 |
2017-11-06 |
Ym Biosciences Australia Pty |
Hæmmere af kinaseaktivitet
|
WO2008079909A1
(en)
|
2006-12-21 |
2008-07-03 |
Plexxikon, Inc. |
Pyrrolo [2,3-b] pyridines as kinase modulators
|
RU2009122670A
(ru)
|
2006-12-21 |
2011-01-27 |
Плекссикон, Инк. (Us) |
Соединения и способы для модуляции киназ и показания к их применению
|
PE20121126A1
(es)
|
2006-12-21 |
2012-08-24 |
Plexxikon Inc |
Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
|
US20080199426A1
(en)
|
2007-01-11 |
2008-08-21 |
Sukhatme Vikas P |
Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders
|
JP2010516692A
(ja)
|
2007-01-19 |
2010-05-20 |
バイエル・ヘルスケア・エルエルシー |
化学療法剤に対し抵抗性を有する癌の処置
|
US20080234267A1
(en)
|
2007-03-20 |
2008-09-25 |
Karen Elizabeth Lackey |
Compounds and Methods of Treatment
|
US20110189167A1
(en)
|
2007-04-20 |
2011-08-04 |
Flynn Daniel L |
Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases
|
WO2008137794A1
(en)
|
2007-05-04 |
2008-11-13 |
Irm Llc |
Compounds and compositions as c-kit and pdgfr kinase inhibitors
|
WO2008138184A1
(fr)
|
2007-05-14 |
2008-11-20 |
Shanghai Hengrui Pharmaceutical Co.Ltd. |
Dérivés de pyrrolo-azacycles, leur procédé de fabrication et leur utilisation en tant qu'inhibiteurs de protéine kinases
|
WO2009003136A1
(en)
|
2007-06-26 |
2008-12-31 |
Rigel Pharmaceuticals, Inc. |
Substituted pyrimidine-2, 4 -diamines for treating cell proliferative disorders
|
CN101801962A
(zh)
|
2007-07-09 |
2010-08-11 |
阿斯利康(瑞典)有限公司 |
用于治疗增殖疾病的三取代嘧啶衍生物
|
WO2009012262A1
(en)
|
2007-07-16 |
2009-01-22 |
The Regents Of The University Of California |
Protein kinase modulating compounds and methods for making and using them
|
EP2170830B1
(en)
|
2007-07-17 |
2014-10-15 |
Plexxikon, Inc. |
2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS
|
KR101552742B1
(ko)
|
2007-07-19 |
2015-09-11 |
머크 샤프 앤드 돔 코포레이션 |
단백질 키나제 억제제로서의 헤테로사이클릭 아미드 화합물
|
SI2176231T1
(sl)
|
2007-07-20 |
2017-01-31 |
Nerviano Medical Sciences S.R.L. |
Substituirani indazolni derivati, aktivni kot kinazni inhibitorji
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
ES2547229T3
(es)
|
2007-08-07 |
2015-10-02 |
Purdue Research Foundation |
Inhibidores de cinasa y usos de los mismos
|
EP2025678A1
(en)
|
2007-08-17 |
2009-02-18 |
Oncalis AG |
Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase
|
WO2009042646A1
(en)
|
2007-09-24 |
2009-04-02 |
Curis, Inc. |
Anti-proliferative agents
|
JP2011501760A
(ja)
|
2007-10-23 |
2011-01-13 |
ノバルティス アーゲー |
呼吸器疾患の処置のためのtrkb抗体の使用
|
US8598172B2
(en)
|
2007-12-04 |
2013-12-03 |
Nerviano Medical Sciences S.R.L. |
Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
|
CN101459004B
(zh)
|
2007-12-14 |
2011-02-09 |
深圳富泰宏精密工业有限公司 |
电子装置的按键面板结构及制造该按键面板结构的方法
|
BRPI0906877A2
(pt)
|
2008-01-17 |
2015-07-28 |
Irm Llc |
Anticorpos anti-trkb aperfeiçoados
|
JP2009203226A
(ja)
|
2008-01-31 |
2009-09-10 |
Eisai R & D Management Co Ltd |
ピリジン誘導体およびピリミジン誘導体を含有するレセプターチロシンキナーゼ阻害剤
|
TW200942537A
(en)
|
2008-02-01 |
2009-10-16 |
Irm Llc |
Compounds and compositions as kinase inhibitors
|
WO2009103076A1
(en)
|
2008-02-15 |
2009-08-20 |
Oxigene, Inc. |
Methods and compositions for enhancing the efficacy of rtk inhibitors
|
US8822500B2
(en)
|
2008-03-19 |
2014-09-02 |
Chembridge Corporation |
Tyrosine kinase inhibitors
|
MX2010010272A
(es)
|
2008-03-19 |
2011-05-25 |
Chembridge Corp |
Nuevos inhibidores de tirosina quinasa.
|
JP5767101B2
(ja)
|
2008-03-28 |
2015-08-19 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
キナーゼ阻害剤として活性な3,4−ジヒドロ−2h−ピラジノ[1,2−a]インドール−1−オン誘導体、これらの調製方法、およびこれらを含む医薬組成物
|
US8158636B2
(en)
|
2008-05-19 |
2012-04-17 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
PE20091846A1
(es)
|
2008-05-19 |
2009-12-16 |
Plexxikon Inc |
DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS
|
EP2282995B1
(en)
|
2008-05-23 |
2015-08-26 |
Novartis AG |
Derivatives of quinolines and quinoxalines as protein tyrosine kinase inhibitors
|
US20090298820A1
(en)
*
|
2008-05-28 |
2009-12-03 |
Wyeth |
3-substituted-1h-pyrrolo[2,3-b]pyridine and 3-substituted-1h-pyrrolo[3,2-b]pyridine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
AU2009257635A1
(en)
|
2008-06-10 |
2009-12-17 |
Plexxikon, Inc. |
5H-Pyrrolo [2,3-b] pyrazine derivatives for kinase modulation, and indications therefor
|
WO2009155527A2
(en)
|
2008-06-19 |
2009-12-23 |
Progenics Pharmaceuticals, Inc. |
Phosphatidylinositol 3 kinase inhibitors
|
US8629135B2
(en)
|
2008-07-14 |
2014-01-14 |
Queen's University At Kingston |
Pharmaceutical compositions comprising RET inhibitors and methods for the treatment of cancer
|
ES2532732T3
(es)
|
2008-07-29 |
2015-03-31 |
Nerviano Medical Sciences S.R.L. |
Uso de un inhibidor de CDK para el tratamiento del glioma
|
JP5323841B2
(ja)
|
2008-09-01 |
2013-10-23 |
シャープ株式会社 |
有機エレクトロルミネセンスパネル、有機エレクトロルミネセンスディスプレイ、有機エレクトロルミネセンス照明、及び、それらの製造方法
|
US20100075916A1
(en)
|
2008-09-05 |
2010-03-25 |
Auspex Pharmaceuticals, Inc. |
Substituted quinazoline inhibitors of growth factor receptor tyrosine kinases
|
EP2161271A1
(en)
|
2008-09-08 |
2010-03-10 |
Università Degli Studi Di Milano - Bicocca |
Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl
|
JP5746032B2
(ja)
|
2008-09-19 |
2015-07-08 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
3,4−ジヒドロ−2H−ピロロ[1,2−a]ピラジン−1−オン誘導体
|
CA2738026C
(en)
|
2008-09-22 |
2017-01-24 |
Array Biopharma Inc. |
Substituted imidazo[1,2b]pyridazine compounds as trk kinase inhibitors
|
EP2331530B8
(en)
|
2008-09-26 |
2013-12-25 |
National Health Research Institutes |
Fused multicyclic compounds as protein kinase inhibitors
|
DK3106463T6
(da)
|
2008-10-22 |
2020-02-24 |
Array Biopharma Inc |
Pyrazolo[1,5-]pyrimidinforbindelse som trk-kinasehæmmer
|
WO2010054058A1
(en)
|
2008-11-06 |
2010-05-14 |
Ambit Bioscience Corporation |
Imidazolothiazole compounds as modulators of protein kinase
|
EP2376084B1
(en)
|
2008-11-24 |
2013-07-17 |
Nerviano Medical Sciences S.r.l. |
CDK inhibitor for the treatment of mesothelioma
|
KR101061599B1
(ko)
|
2008-12-05 |
2011-09-02 |
한국과학기술연구원 |
비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물
|
JO3265B1
(ar)
|
2008-12-09 |
2018-09-16 |
Novartis Ag |
مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
|
WO2010111527A1
(en)
|
2009-03-26 |
2010-09-30 |
Plexxikon, Inc. |
Pyrazolo [ 3, 4 -b] pyridines as kinase inhibitors and their medical use
|
US8492374B2
(en)
|
2009-04-29 |
2013-07-23 |
Industrial Technology Research Institute |
Azaazulene compounds
|
EP3009428B1
(en)
|
2009-05-08 |
2018-02-21 |
Astellas Pharma Inc. |
Diamino heterocyclic carboxamide compound
|
US8765747B2
(en)
|
2009-06-12 |
2014-07-01 |
Dana-Farber Cancer Institute, Inc. |
Fused 2-aminothiazole compounds
|
ES2570756T3
(es)
|
2009-06-15 |
2016-05-20 |
Nerviano Medical Sciences Srl |
Derivados pirimidinilpirrolopiridinona sustituidos, proceso para su preparación y su uso como inhibidores de cinasa
|
AR077468A1
(es)
|
2009-07-09 |
2011-08-31 |
Array Biopharma Inc |
Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
|
MX2012002066A
(es)
|
2009-08-17 |
2012-03-29 |
Intellikine Inc |
Compuestos heterociclicos y usos de los mismos.
|
KR101256018B1
(ko)
|
2009-08-20 |
2013-04-18 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 갖는 1,3,6-치환된 인돌 화합물
|
FR2951172B1
(fr)
*
|
2009-10-13 |
2014-09-26 |
Pf Medicament |
Derives pyrazolopyridines en tant qu'agent anticancereux
|
KR101147550B1
(ko)
|
2009-10-22 |
2012-05-17 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 가지는 2,7-치환된 티에노[3,2-d]피리미딘 화합물
|
KR101116756B1
(ko)
|
2009-10-27 |
2012-03-13 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 갖는 신규의 1,6-치환된 인돌 화합물
|
EA029273B1
(ru)
|
2009-10-29 |
2018-03-30 |
Джиноско |
Киназные ингибиторы
|
US8629132B2
(en)
|
2009-11-13 |
2014-01-14 |
Genosco |
Kinase inhibitors
|
KR101094446B1
(ko)
|
2009-11-19 |
2011-12-15 |
한국과학기술연구원 |
단백질 키나아제 저해활성을 가지는 2,4,7-치환된 티에노[3,2-d]피리미딘 화합물
|
EP2519517B1
(en)
|
2009-12-29 |
2015-03-25 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
JP5676650B2
(ja)
|
2010-01-29 |
2015-02-25 |
ハンミ・サイエンス・カンパニー・リミテッドHanmi Science Co., Ltd. |
プロテインキナーゼ阻害活性を有するチエノ[3,2−d]ピリミジン誘導体
|
EP2528918B1
(en)
|
2010-01-29 |
2014-09-10 |
Nerviano Medical Sciences S.r.l. |
6,7-dihydroimidazo[1,5-a]pyrazin-8(5h)-one derivatives as protein kinase modulators
|
KR101483215B1
(ko)
|
2010-01-29 |
2015-01-16 |
한미약품 주식회사 |
단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체
|
US9161944B2
(en)
|
2010-02-18 |
2015-10-20 |
Inserm (Institut National De La Sante Et De La Sante Et De La Recherche Medicale) |
Method for preventing cancer metastasis
|
TWI619713B
(zh)
|
2010-04-21 |
2018-04-01 |
普雷辛肯公司 |
用於激酶調節的化合物和方法及其適應症
|
HUE035337T2
(en)
|
2010-05-20 |
2018-05-02 |
Array Biopharma Inc |
Macrocyclic compounds as TRK kinase inhibitors
|
US8637516B2
(en)
|
2010-09-09 |
2014-01-28 |
Irm Llc |
Compounds and compositions as TRK inhibitors
|
WO2012034095A1
(en)
|
2010-09-09 |
2012-03-15 |
Irm Llc |
Compounds and compositions as trk inhibitors
|
WO2012047017A2
(ko)
|
2010-10-05 |
2012-04-12 |
크리스탈지노믹스(주) |
2,3-디히드로-이소인돌-1-온 유도체 및 이를 포함하는 조성물
|
JP2014005206A
(ja)
|
2010-10-22 |
2014-01-16 |
Astellas Pharma Inc |
アリールアミノヘテロ環カルボキサミド化合物
|
EP2668188B1
(en)
|
2011-01-26 |
2016-05-18 |
Nerviano Medical Sciences S.r.l. |
Tricyclic derivatives, process for their preparation and their use as kinase inhibitors
|
WO2012101032A1
(en)
|
2011-01-26 |
2012-08-02 |
Nerviano Medical Sciences S.R.L. |
Tricyclic pyrrolo derivatives, process for their preparation and their use as kinase inhibitors
|
CN102093421B
(zh)
|
2011-01-28 |
2014-07-02 |
北京康辰药业有限公司 |
一种含磷取代基的喹啉类化合物及其制备方法、以及含有该化合物的药物组合物及其应用
|
TR201816421T4
(tr)
|
2011-02-07 |
2018-11-21 |
Plexxikon Inc |
Kinaz modülasyonu için bileşikler ve metotlar ve bunların endikasyonları.
|
WO2012113774A1
(en)
|
2011-02-24 |
2012-08-30 |
Nerviano Medical Sciences S.R.L. |
Thiazolylphenyl-benzenesulfonamido derivatives as kinase inhibitors
|
CA2828219A1
(en)
|
2011-02-25 |
2012-08-30 |
Irm Llc |
Pyrazolo [1,5-a] pyridines as trk inhibitors
|
WO2012135631A1
(en)
|
2011-03-30 |
2012-10-04 |
Arrien Pharmaeuticals Llc |
Substituted 5-(pyrazin-2-yl)-1h-pyrazolo [3, 4-b] pyridine and pyrazolo [3, 4-b] pyridine derivatives as protein kinase inhibitors
|
WO2012135800A1
(en)
|
2011-04-01 |
2012-10-04 |
University Of Utah Research Foundation |
Substituted n-phenylpyrimidin-2-amine analogs as inhibitors of the axl kinase
|
EP2702055A1
(en)
|
2011-04-11 |
2014-03-05 |
Nerviano Medical Sciences S.r.l. |
Pyrazolyl-pyrimidine derivatives as kinase inhibitors
|
BR112013026137B1
(pt)
|
2011-04-19 |
2020-12-01 |
Nerviano Medical Sciences S.R.L |
pirimidinil-pirróis substituídos ativos como inibidores da quinase
|
AR086042A1
(es)
*
|
2011-04-28 |
2013-11-13 |
Galapagos Nv |
Compuesto util para el tratamiento de enfermedades degenerativas e inflamatorias y composicion farmaceutica
|
MX342509B
(es)
|
2011-05-12 |
2016-10-03 |
Nerviano Medical Sciences Srl |
Compuestos de indazol sustituidos como inhibidores de las cinasas de proteina.
|
KR101960555B1
(ko)
|
2011-05-13 |
2019-03-20 |
어레이 바이오파마 인크. |
Trka 키나제 저해제로서의 피롤리디닐 유레아 및 피롤리디닐 티오유레아 화합물
|
RU2477723C2
(ru)
|
2011-06-16 |
2013-03-20 |
Общество С Ограниченной Ответственностью "Фьюжн Фарма" |
Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе
|
CN102827073A
(zh)
*
|
2011-06-17 |
2012-12-19 |
安吉奥斯医药品有限公司 |
治疗活性组合物和它们的使用方法
|
WO2013016720A2
(en)
|
2011-07-28 |
2013-01-31 |
Gerinda Therapeutics, Inc. |
Novel substituted biarylheterocycle derivatives as protein kinase inhibitors for the treatment of cancer and other diseases
|
JP6016915B2
(ja)
|
2011-07-28 |
2016-10-26 |
ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ |
キナーゼ阻害剤として活性なアルキニル置換ピリミジニルピロール
|
CA2848369A1
(en)
|
2011-08-04 |
2013-02-07 |
National Cancer Center |
Fusion gene of kif5b gene and ret gene, and method for determining effectiveness of cancer treatment targeting fusion gene
|
SG2014012728A
(en)
|
2011-08-23 |
2014-06-27 |
Foundation Medicine Inc |
Novel kif5b-ret fusion molecules and uses thereof
|
CA2846496C
(en)
|
2011-09-02 |
2020-07-14 |
The Regents Of The University Of California |
Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
|
WO2013036232A2
(en)
|
2011-09-08 |
2013-03-14 |
Deciphera Pharmaceuticals, Llc |
Methods and compositions for the treatment of myeloproliferative diseases and other proliferative diseases
|
US8846712B2
(en)
*
|
2011-09-12 |
2014-09-30 |
Sanofi |
6-(4-hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
CN102408411B
(zh)
|
2011-09-19 |
2014-10-22 |
北京康辰药业股份有限公司 |
一种含喹啉基的羟肟酸类化合物及其制备方法、以及含有该化合物的药物组合物及其应用
|
WO2013042137A1
(en)
|
2011-09-19 |
2013-03-28 |
Aurigene Discovery Technologies Limited |
Bicyclic heterocycles as irak4 inhibitors
|
ES2660265T3
(es)
|
2011-10-07 |
2018-03-21 |
Nerviano Medical Sciences S.R.L. |
Derivados de 3,4-dihidropirrolo[1,2-a]pirazin-1(2h)-ona 4-alquil-sustituidos como inhibidores de cinasa
|
WO2013050446A1
(en)
|
2011-10-07 |
2013-04-11 |
Nerviano Medical Sciences S.R.L. |
SUBSTITUTED 3,4-DIHYDROPYRROLO[1,2-a]PYRAZIN-1(2H)-ONE DERIVATIVES AS KINASES INHIBITORS
|
AU2012339753A1
(en)
|
2011-11-14 |
2014-06-19 |
Tesaro, Inc. |
Modulating certain tyrosine kinases
|
WO2013081188A1
(ja)
|
2011-11-30 |
2013-06-06 |
独立行政法人国立がん研究センター |
誘導悪性幹細胞
|
RU2705577C2
(ru)
|
2011-12-30 |
2019-11-08 |
Ханми Фарм. Ко., Лтд. |
ПРОИЗВОДНЫЕ ТИЕНО[3,2-d]ПИРИМИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ПРОТЕИНКИНАЗ
|
US8377946B1
(en)
|
2011-12-30 |
2013-02-19 |
Pharmacyclics, Inc. |
Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors
|
JP2015109806A
(ja)
|
2012-03-22 |
2015-06-18 |
アステラス製薬株式会社 |
新規ret融合体の検出法
|
WO2013161919A1
(ja)
|
2012-04-26 |
2013-10-31 |
小野薬品工業株式会社 |
Trk阻害化合物
|
CA2871540A1
(en)
|
2012-05-10 |
2013-11-14 |
Synta Pharmaceuticals Corp. |
Treating cancer with hsp90 inhibitory compounds
|
BR112014028841B1
(pt)
|
2012-05-23 |
2021-01-12 |
Nerviano Medical Sciences S.R.L. |
Formas cristalinas 1 e 2, composição farmacêutica, uso da forma cristalina 1 para o tratamento de um estado de doença tratável pela inibição de alk e processo para a preparação de n-[5-(3,5-difluoro-benzil)-1h-indazol-3-il]-4-(4-metilpiperazin-1-il)-2-(tetra-hidro-piran-4-ilamino)- benzamida
|
TWI585088B
(zh)
|
2012-06-04 |
2017-06-01 |
第一三共股份有限公司 |
作爲激酶抑制劑之咪唑并[1,2-b]嗒衍生物
|
DK2872491T3
(da)
|
2012-07-11 |
2021-08-09 |
Blueprint Medicines Corp |
Inhibitorer af fibroblastvækstfaktorreceptoren
|
WO2014017491A1
(ja)
|
2012-07-26 |
2014-01-30 |
独立行政法人国立がん研究センター |
Cep55遺伝子とret遺伝子との融合遺伝子
|
BR112015002152B1
(pt)
|
2012-08-02 |
2021-04-27 |
Nerviano Medical Sciences S.R.L. |
Compostos de pirróis substituídos ativos como inibidores de quinases, processo para a preparação de tais compostos, composição farmacêutica, método in vitro para a inibição da atividade de proteínas quinases da família jak e produto compreendendo os referidos compostos
|
CN114129566A
(zh)
|
2012-09-07 |
2022-03-04 |
埃克塞里艾克西斯公司 |
用于治疗肺腺癌的met、vegfr和ret的抑制剂
|
SG10201704588XA
(en)
|
2012-09-25 |
2017-07-28 |
Chugai Pharmaceutical Co Ltd |
Ret inhibitor
|
CN104870446B
(zh)
|
2012-11-07 |
2019-08-13 |
内尔维阿诺医学科学有限公司 |
取代的嘧啶基和吡啶基吡咯并吡啶酮类、其制备方法及其作为激酶抑制剂的用途
|
EP2917183A1
(en)
|
2012-11-12 |
2015-09-16 |
Ignyta, Inc. |
Bendamustine derivatives and methods of using same
|
WO2014078325A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
MX366761B
(es)
|
2012-11-13 |
2019-07-23 |
Array Biopharma Inc |
Compuestos bíciclicos de urea, tiourea, guanidina y cianoguanidina útiles para el tratamiento del dolor.
|
WO2014078331A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
N-(arylalkyl)-n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
US9809578B2
(en)
|
2012-11-13 |
2017-11-07 |
Array Biopharma Inc. |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors
|
WO2014078408A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
WO2014078322A1
(en)
|
2012-11-13 |
2014-05-22 |
Array Biopharma Inc. |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors
|
US9828360B2
(en)
|
2012-11-13 |
2017-11-28 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9790178B2
(en)
|
2012-11-13 |
2017-10-17 |
Array Biopharma Inc. |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors
|
US9546156B2
(en)
|
2012-11-13 |
2017-01-17 |
Array Biopharma Inc. |
N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors
|
DK2922844T3
(en)
|
2012-11-13 |
2018-03-05 |
Array Biopharma Inc |
N-PYRROLIDINYL, N'-PYRAZOLYL-URINE, THIOURINE, GUANIDINE AND CYANOGUANIDE COMPOUNDS AS TRKA-KINASE INHIBITORS
|
KR20150090116A
(ko)
|
2012-11-29 |
2015-08-05 |
예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 |
종양 전이를 예방하고, 암을 치료하고 예후를 예측하며, 추정상의 전이 억제인자 물질을 확인하는 방법
|
CN103848785B
(zh)
|
2012-12-04 |
2016-07-13 |
上海医药集团股份有限公司 |
一类氘代3-氰基喹啉类化合物、其药用组合物、制备方法及其用途
|
FR3000494B1
(fr)
|
2012-12-28 |
2015-08-21 |
Oribase Pharma |
Nouveaux derives d'azaindoles en tant qu'inhibiteurs de proteines kinases
|
FR3000492B1
(fr)
|
2012-12-28 |
2015-09-11 |
Oribase Pharma |
Nouveaux derives azaindole en tant qu'inhibiteurs multikinases
|
AU2013371146C1
(en)
|
2012-12-28 |
2019-01-17 |
Crystalgenomics, Inc. |
2,3-dihydro-isoindole-1-on derivative as BTK kinase suppressant, and pharmaceutical composition including same
|
FR3000493A1
(fr)
|
2012-12-28 |
2014-07-04 |
Oribase Pharma |
Nouveaux inhibiteurs de proteines kinases
|
TW201443037A
(zh)
*
|
2013-01-09 |
2014-11-16 |
Gilead Sciences Inc |
治療用化合物
|
BR122017003181A2
(pt)
|
2013-02-19 |
2019-09-10 |
Ono Pharmaceutical Co |
composto inibidor de trk, composição farmacêutica e medicamento compreendendo dito composto e seu uso para profilaxia e/ou terapia de doença relacionada à trk e/ou para inibir trk
|
WO2014160524A1
(en)
|
2013-03-14 |
2014-10-02 |
The Trustees Of The University Of Pennsylvania |
Cardio- metabolic and cascular effects of glp-1 metabolites
|
CN105051027A
(zh)
|
2013-03-15 |
2015-11-11 |
葛兰素史密斯克莱知识产权发展有限公司 |
作为转染期间重排(ret)激酶抑制剂的吡啶衍生物
|
WO2014160521A1
(en)
|
2013-03-15 |
2014-10-02 |
Blueprint Medicines Corporation |
Piperazine derivatives and their use as kit modulators
|
US8937071B2
(en)
|
2013-03-15 |
2015-01-20 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds as rearranged during transfection (RET) inhibitors
|
EP2968322B1
(en)
*
|
2013-03-15 |
2018-12-26 |
The Trustees of Columbia University in the City of New York |
Map kinase modulators and uses thereof
|
ES2646019T3
(es)
|
2013-05-14 |
2017-12-11 |
Nerviano Medical Sciences S.R.L. |
Derivados de 6-amino-7-deaza-purina, proceso para su preparación y su uso como inhibidores de cinasa
|
SG11201509338QA
(en)
|
2013-05-30 |
2015-12-30 |
Plexxikon Inc |
Compounds for kinase modulation, and indications therefor
|
EP3027655B1
(en)
|
2013-07-30 |
2019-08-21 |
Blueprint Medicines Corporation |
Ntrk2 fusions
|
WO2015017528A1
(en)
|
2013-07-30 |
2015-02-05 |
Blueprint Medicines Corporation |
Pik3c2g fusions
|
CN105658814A
(zh)
|
2013-08-20 |
2016-06-08 |
日本国立癌症研究中心 |
在肺癌中检测出的新型融合基因
|
SG11201601341QA
(en)
|
2013-08-30 |
2016-03-30 |
Ambit Biosciences Corp |
Biaryl acetamide compounds and methods of use thereof
|
EP3409674B1
(en)
|
2013-10-17 |
2022-04-06 |
Blueprint Medicines Corporation |
Process for preparing compositions useful for treating disorders related to kit
|
US9334263B2
(en)
|
2013-10-17 |
2016-05-10 |
Blueprint Medicines Corporation |
Compositions useful for treating disorders related to kit
|
JP6458023B2
(ja)
|
2013-10-25 |
2019-01-23 |
ブループリント メディシンズ コーポレイション |
繊維芽細胞成長因子受容体の阻害剤
|
GB201321146D0
(en)
|
2013-11-29 |
2014-01-15 |
Cancer Rec Tech Ltd |
Quinazoline compounds
|
WO2015082887A2
(en)
|
2013-12-02 |
2015-06-11 |
Bergenbio As |
Use of kinase inhibitors
|
US9695165B2
(en)
|
2014-01-15 |
2017-07-04 |
Blueprint Medicines Corporation |
Inhibitors of the fibroblast growth factor receptor
|
EA031863B1
(ru)
|
2014-01-24 |
2019-03-29 |
ТиПи ТЕРАПЬЮТИКС, ИНК. |
Диарильные макроциклы в качестве модуляторов протеинкиназ
|
MX2021001583A
(es)
|
2014-02-14 |
2023-02-08 |
Exelixis Inc |
Formas sólidas cristalinas de n-{4-[(6,7-dimetoxiquinolin-4-il)oxi ] fenil}-n'-(4-fluorofenil)ciclopropan-1,1-dicarboxamida, procesos para elaboración y métodos de uso.
|
US10231965B2
(en)
|
2014-02-20 |
2019-03-19 |
Ignyta, Inc. |
Molecules for administration to ROS1 mutant cancer cells
|
WO2015161274A1
(en)
|
2014-04-18 |
2015-10-22 |
Blueprint Medicines Corporation |
Pik3ca fusions
|
WO2015161277A1
(en)
|
2014-04-18 |
2015-10-22 |
Blueprint Medicines Corporation |
Met fusions
|
MA40434B1
(fr)
|
2014-05-15 |
2019-09-30 |
Array Biopharma Inc |
1-((3s,4r)-4-(3-fluorophényl)-1-(2-méthoxyéthyl)pyrrolidin-3-yl)-3-(4-méthyl-3-(2-méthylpyrimidin-5-yl)-1-phényl-1h-pyrazol-5-yl)urée comme inhibiteur de la kinase trka
|
US10246750B2
(en)
|
2014-06-10 |
2019-04-02 |
Blueprint Medicines Corporation |
Method for detection of a TECR:PKN1 or an ANXA4:PKN1 gene fusion
|
WO2015191666A2
(en)
|
2014-06-10 |
2015-12-17 |
Blueprint Medicines Corporation |
Raf1 fusions
|
EP3169804B3
(en)
|
2014-07-17 |
2019-09-18 |
Blueprint Medicines Corporation |
Fgr fusions
|
CN105272930B
(zh)
|
2014-07-17 |
2018-07-13 |
广东东阳光药业有限公司 |
取代脲衍生物及其在药物中的应用
|
EP3169809B1
(en)
|
2014-07-17 |
2020-04-29 |
Blueprint Medicines Corporation |
Prkc fusions
|
US10370723B2
(en)
|
2014-07-17 |
2019-08-06 |
Blueprint Medicines Corporation |
TERT fusions
|
WO2016022569A1
(en)
|
2014-08-04 |
2016-02-11 |
Blueprint Medicines Corporation |
Compositions useful for treating disorders related to kit
|
TR201908736T4
(tr)
|
2014-08-18 |
2019-07-22 |
Ono Pharmaceutical Co |
Trk-inhibe eden bileşiğin asit eklenmiş tuzu.
|
CN107148418A
(zh)
|
2014-09-08 |
2017-09-08 |
葛兰素史密斯克莱知识产权发展有限公司 |
2‑(4‑(4‑乙氧基‑6‑氧代‑1,6‑二氢吡啶‑3‑基)‑2‑氟苯基)‑n‑(5‑(1,1,1‑三氟‑2‑甲基丙‑2‑基)异噁唑‑3‑基)乙酰胺的晶型
|
EP3191450B1
(en)
|
2014-09-10 |
2019-04-10 |
GlaxoSmithKline Intellectual Property Development Limited |
Pyridone derivatives as rearranged during transfection (ret) kinase inhibitors
|
MY187169A
(en)
|
2014-09-10 |
2021-09-07 |
Glaxosmithkline Ip Dev Ltd |
Novel compounds as rearranged during transfection (ret) inhibitors
|
TWI538914B
(zh)
|
2014-10-03 |
2016-06-21 |
國立交通大學 |
蛋白質激酶之選擇性抑制劑、其醫藥組成物及其用途
|
CN107108631B
(zh)
*
|
2014-11-14 |
2020-06-16 |
内尔维阿诺医学科学有限公司 |
作为蛋白激酶抑制剂的6-氨基-7-二环-7-脱氮-嘌呤衍生物
|
DK3699181T3
(da)
|
2014-11-16 |
2023-03-20 |
Array Biopharma Inc |
Krystallinsk form af (s)-n-(5-((r)-2-(2,5-difluorphenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidin-1-carboxamidhydrogensulfat
|
US20170356052A1
(en)
|
2014-11-18 |
2017-12-14 |
Blueprint Medicines Corporation |
Prkacb fusions
|
WO2016096709A1
(en)
|
2014-12-16 |
2016-06-23 |
Eudendron S.R.L. |
Heterocyclic derivatives modulating activity of certain protein kinases
|
US10202365B2
(en)
|
2015-02-06 |
2019-02-12 |
Blueprint Medicines Corporation |
2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors
|
KR101675984B1
(ko)
|
2015-02-23 |
2016-11-14 |
한양대학교 에리카산학협력단 |
티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
|
US20180045727A1
(en)
|
2015-03-03 |
2018-02-15 |
Caris Mpi, Inc. |
Molecular profiling for cancer
|
US10364247B2
(en)
|
2015-04-21 |
2019-07-30 |
Ruijin Hospital Affiliated To Shanghai Jiao Tong University School Of Medicine |
Preparation and use of novel protein kinase inhibitors
|
GB201512365D0
(en)
|
2015-07-15 |
2015-08-19 |
King S College London |
Novel therapy
|
EP3322706B1
(en)
*
|
2015-07-16 |
2020-11-11 |
Array Biopharma, Inc. |
Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors
|
EP3120851A1
(en)
|
2015-07-21 |
2017-01-25 |
Pangaea Biotech S.L. |
4-amino-6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8h)-one for treatment of solid cancers
|
KR101766194B1
(ko)
|
2015-08-07 |
2017-08-10 |
한국과학기술연구원 |
RET 키나아제 저해제인 신규 3-(이속사졸-3-일)-피라졸로[3,4-d]피리미딘-4-아민 화합물
|
WO2017027883A1
(en)
|
2015-08-13 |
2017-02-16 |
San Diego State University Research Foundation |
Atropisomerism for increased kinase inhibitor selectivity
|
MA41559A
(fr)
|
2015-09-08 |
2017-12-26 |
Taiho Pharmaceutical Co Ltd |
Composé de pyrimidine condensé ou un sel de celui-ci
|
WO2017049462A1
(zh)
|
2015-09-22 |
2017-03-30 |
合肥中科普瑞昇生物医药科技有限公司 |
一类新型的flt3激酶抑制剂及其用途
|
CN105255927B
(zh)
|
2015-09-30 |
2018-07-27 |
温州医科大学附属第一医院 |
一种kiaa1217-ret融合基因
|
TWI787018B
(zh)
|
2015-11-02 |
2022-12-11 |
美商纜圖藥品公司 |
轉染過程重排之抑制劑
|
EP3387145A1
(en)
|
2015-12-08 |
2018-10-17 |
Boehringer Ingelheim International GmbH |
Method using a ret fusion gene as a biomarker to select non-small cell lung cancer (nsclc) and thyroid cancer patients for a cancer treatment
|
JP6871869B2
(ja)
|
2016-01-15 |
2021-05-19 |
公益財団法人がん研究会 |
新規融合体及びその検出法
|
TWI620748B
(zh)
|
2016-02-05 |
2018-04-11 |
National Health Research Institutes |
氨基噻唑化合物及其用途
|
WO2017145050A1
(en)
|
2016-02-23 |
2017-08-31 |
Glaxosmithkline Intellectual Property Development Limited |
Pyridylpyridone derivative useful as a ret kinase inhibitor in the treatment of ibs and cancer
|
PT3269370T
(pt)
|
2016-02-23 |
2020-03-05 |
Taiho Pharmaceutical Co Ltd |
Novo composto de pirimidina condensada ou sal do mesmo
|
TW201738228A
(zh)
|
2016-03-17 |
2017-11-01 |
藍圖醫藥公司 |
Ret之抑制劑
|
US10045991B2
(en)
|
2016-04-04 |
2018-08-14 |
Loxo Oncology, Inc. |
Methods of treating pediatric cancers
|
DK3442535T3
(da)
*
|
2016-04-15 |
2022-09-05 |
Cancer Research Tech Ltd |
Heterocykliske stoffer som as ret-kinase-hæmmere
|
SG10201911665UA
(en)
|
2016-04-15 |
2020-01-30 |
Cancer Research Tech Ltd |
Heterocyclic compounds as ret kinase inhibitors
|
TWI704148B
(zh)
|
2016-10-10 |
2020-09-11 |
美商亞雷生物製藥股份有限公司 |
作為ret激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物
|
JOP20190077A1
(ar)
|
2016-10-10 |
2019-04-09 |
Array Biopharma Inc |
مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret
|