DK490288D0 - Hidtil ukendte forbindelser - Google Patents

Hidtil ukendte forbindelser

Info

Publication number
DK490288D0
DK490288D0 DK490288A DK490288A DK490288D0 DK 490288 D0 DK490288 D0 DK 490288D0 DK 490288 A DK490288 A DK 490288A DK 490288 A DK490288 A DK 490288A DK 490288 D0 DK490288 D0 DK 490288D0
Authority
DK
Denmark
Prior art keywords
group
substituted
compounds
unsubstituted
pharmaceutically acceptable
Prior art date
Application number
DK490288A
Other languages
English (en)
Other versions
DK490288A (da
DK175176B1 (da
Inventor
Richard Mark Hindley
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27263577&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK490288(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878720825A external-priority patent/GB8720825D0/en
Priority claimed from GB878727987A external-priority patent/GB8727987D0/en
Priority claimed from GB888802454A external-priority patent/GB8802454D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of DK490288D0 publication Critical patent/DK490288D0/da
Publication of DK490288A publication Critical patent/DK490288A/da
Application granted granted Critical
Publication of DK175176B1 publication Critical patent/DK175176B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
DK198804902A 1987-09-04 1988-09-02 Forbindelsen 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl)-2,4-thiazolidindion, et farmaceutisk præparat indeholdende forbindelsen, forbindelsen som en aktiv terapeutisk bestanddel og anvendelsen af forbindelsen til fremstilling af et medikament DK175176B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB878720825A GB8720825D0 (en) 1987-09-04 1987-09-04 Compounds
GB8720825 1987-09-04
GB878727987A GB8727987D0 (en) 1987-11-30 1987-11-30 Novel compounds
GB8727987 1987-11-30
GB8802454 1988-02-04
GB888802454A GB8802454D0 (en) 1988-02-04 1988-02-04 Compounds

Publications (3)

Publication Number Publication Date
DK490288D0 true DK490288D0 (da) 1988-09-02
DK490288A DK490288A (da) 1989-03-05
DK175176B1 DK175176B1 (da) 2004-06-21

Family

ID=27263577

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198804902A DK175176B1 (da) 1987-09-04 1988-09-02 Forbindelsen 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl)-2,4-thiazolidindion, et farmaceutisk præparat indeholdende forbindelsen, forbindelsen som en aktiv terapeutisk bestanddel og anvendelsen af forbindelsen til fremstilling af et medikament
DK200001556A DK200001556A (da) 1987-09-04 2000-10-18 Substituerede thiazolidindionderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200001556A DK200001556A (da) 1987-09-04 2000-10-18 Substituerede thiazolidindionderivater

Country Status (19)

Country Link
US (1) US5002953A (da)
EP (2) EP0842925A1 (da)
JP (6) JP2614497B2 (da)
KR (1) KR0164207B1 (da)
AT (1) ATE186724T1 (da)
AU (1) AU611938B2 (da)
CA (1) CA1328452C (da)
CZ (1) CZ391691A3 (da)
DE (2) DE10199003I1 (da)
DK (2) DK175176B1 (da)
ES (1) ES2137915T3 (da)
GR (1) GR3031873T3 (da)
HK (1) HK1011029A1 (da)
IE (1) IE20000683A1 (da)
LU (1) LU90711I2 (da)
NL (1) NL300034I2 (da)
NZ (1) NZ226027A (da)
PT (1) PT88410B (da)
SG (1) SG59988A1 (da)

Families Citing this family (274)

* Cited by examiner, † Cited by third party
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US5194443A (en) * 1987-09-04 1993-03-16 Beecham Group P.L.C. Compounds
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BR9711098B1 (pt) * 1996-07-01 2011-10-04 compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
US6372750B2 (en) * 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
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AU774839B2 (en) * 1997-02-18 2004-07-08 Smithkline Beecham Plc Process for the preparation of substituted thiazolidinedione
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EP2266576A1 (en) * 1997-06-18 2010-12-29 SmithKline Beecham Limited Treatment of diabetes with thiazolidinedione and sulphonylurea
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BR9813019A (pt) 1997-10-02 2000-09-05 Sankyo Co Derivados do ácido amidocarboxìlico, agentes para diminuir a glicose do sangue, redutor de lipìdio, para melhorar a resistência à insulina, anti-inflamatório, para imuno regulagem, para inibir a aldose reductase, para inibir a 5-lipoxigenase, para a geração de supressor de peróxido de lipìdio, para ativar a ppar, para minorar a osteoporose, e, composições para a terapia ou prevenção da diabete melito, da hiperlipemia, da obesidade, da tolerância à glicose prejudicada, da resistência à insulina que não a igt, do fìgado gorduroso, de complicações diabéticas, da arterioesclerose, da diabete melito gestacional, da sìndrome do ovário policìstico, da artroesteìte, da artrite reumática, de doenças alérgicas, da asma, do câncer, de doenças auto imunes, da pancreatite, e de cataratas
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GB9723295D0 (en) * 1997-11-04 1998-01-07 Smithkline Beecham Plc Novel process
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EP0842925A1 (en) 1998-05-20
JPH09183772A (ja) 1997-07-15
JP2614497B2 (ja) 1997-05-28
CZ391691A3 (en) 1993-03-17
JP2837139B2 (ja) 1998-12-14
JPH09183726A (ja) 1997-07-15
ES2137915T3 (es) 2000-01-01
DK490288A (da) 1989-03-05
KR890005095A (ko) 1989-05-11
PT88410B (pt) 1992-10-30
EP0306228A1 (en) 1989-03-08
JPH10194970A (ja) 1998-07-28
IE20000683A1 (en) 2002-07-24
JPH09183771A (ja) 1997-07-15
NL300034I1 (nl) 2001-03-01
DK200001556A (da) 2000-10-18
PT88410A (pt) 1989-07-31
JPH10194971A (ja) 1998-07-28
AU611938B2 (en) 1991-06-27
CA1328452C (en) 1994-04-12
AU2173888A (en) 1989-03-09
GR3031873T3 (en) 2000-02-29
NL300034I2 (nl) 2001-05-01
DE10199003I1 (de) 2003-06-12
DK175176B1 (da) 2004-06-21
EP0306228B1 (en) 1999-11-17
JPH01131169A (ja) 1989-05-24
SG59988A1 (en) 1999-02-22
DE3856378D1 (de) 1999-12-23
ATE186724T1 (de) 1999-12-15
JP2817840B2 (ja) 1998-10-30
DE10199003I2 (da) 2003-09-18
LU90711I2 (fr) 2001-03-05
DE3856378T2 (de) 2000-05-11
KR0164207B1 (ko) 1999-01-15
HK1011029A1 (en) 1999-07-02
US5002953A (en) 1991-03-26
NZ226027A (en) 1992-03-26

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