DK2311879T3 - Monoclonal antibodies to claudin-18 for the treatment of cancer - Google Patents

Monoclonal antibodies to claudin-18 for the treatment of cancer Download PDF

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Publication number
DK2311879T3
DK2311879T3 DK10011776.1T DK10011776T DK2311879T3 DK 2311879 T3 DK2311879 T3 DK 2311879T3 DK 10011776 T DK10011776 T DK 10011776T DK 2311879 T3 DK2311879 T3 DK 2311879T3
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Prior art keywords
seq
positions
antibody
cells
cdr3
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DK10011776.1T
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Danish (da)
English (en)
Inventor
Ugur Sahin
Özlem Türeci
Dirk Usener
Stefan Fritz
Gunda Brandenburg
Harald-Gerhard Geppert
Anja Kristina Schröder
Philippe Thiel
Christoph Uherek
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Ganymed Pharmaceuticals Gmbh
JOHANNES GUTENBERG-UNIVERSITÄT MAINZ vertreten durch den Präsidenten
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    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
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