SG10201903351SA - Monoclonal antibodies against claudin-18 for treatment of cancer - Google Patents

Monoclonal antibodies against claudin-18 for treatment of cancer

Info

Publication number
SG10201903351SA
SG10201903351SA SG10201903351SA SG10201903351SA SG10201903351SA SG 10201903351S A SG10201903351S A SG 10201903351SA SG 10201903351S A SG10201903351S A SG 10201903351SA SG 10201903351S A SG10201903351S A SG 10201903351SA SG 10201903351S A SG10201903351S A SG 10201903351SA
Authority
SG
Singapore
Prior art keywords
cancer
treatment
monoclonal antibodies
antibodies against
against claudin
Prior art date
Application number
SG10201903351SA
Inventor
Sahin Ugur
Türeci Özlem
Usener Dirk
Fritz Stefan
Uherek Cristoph
Brandenburg Gunda
Geppert Harald-Gerhard
Kristina Schröder Anja
Thiel Philippe
Original Assignee
Ganymed Pharmaceuticals Ag
Johannes Gutenberg Universitaet Mainz Vertreten Durch Den Praesidenten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ganymed Pharmaceuticals Ag, Johannes Gutenberg Universitaet Mainz Vertreten Durch Den Praesidenten filed Critical Ganymed Pharmaceuticals Ag
Publication of SG10201903351SA publication Critical patent/SG10201903351SA/en

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    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
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Abstract

MONOCLONAL ANTIBODIES AGAINST CLAUDIN- FOR TREATMENT OF CANCER The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLDI 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder. Fig. 1 152
SG10201903351SA 2005-11-24 2006-11-24 Monoclonal antibodies against claudin-18 for treatment of cancer SG10201903351SA (en)

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