HRP20171337T1 - Monoklonska antitijela protiv klaudina-18 za liječenje karcinoma - Google Patents

Monoklonska antitijela protiv klaudina-18 za liječenje karcinoma

Info

Publication number
HRP20171337T1
HRP20171337T1 HRP20171337TT HRP20171337T HRP20171337T1 HR P20171337 T1 HRP20171337 T1 HR P20171337T1 HR P20171337T T HRP20171337T T HR P20171337TT HR P20171337 T HRP20171337 T HR P20171337T HR P20171337 T1 HRP20171337 T1 HR P20171337T1
Authority
HR
Croatia
Prior art keywords
cancer
treatment
monoclonal antibodies
antibodies against
against claudin
Prior art date
Application number
HRP20171337TT
Other languages
English (en)
Inventor
Ugur Sahin
Özlem TÜRECI
Dirk Usener
Stefan Fritz
Christoph Uherek
Gunda Brandenburg
Harald-Gerhard Geppert
Anja Kristina SCHRÖDER
Philippe Thiel
Original Assignee
Ganymed Pharmaceuticals Gmbh
Johannes Gutenberg-Universität Mainz, Vertreten Durch Den Präsidenten
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ganymed Pharmaceuticals Gmbh, Johannes Gutenberg-Universität Mainz, Vertreten Durch Den Präsidenten filed Critical Ganymed Pharmaceuticals Gmbh
Publication of HRP20171337T1 publication Critical patent/HRP20171337T1/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1063—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from stomach or intestines
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