DK1073656T3 - Imidazopyridinderivater, der inhiberer mavesyresecernering - Google Patents

Imidazopyridinderivater, der inhiberer mavesyresecernering

Info

Publication number
DK1073656T3
DK1073656T3 DK99947037T DK99947037T DK1073656T3 DK 1073656 T3 DK1073656 T3 DK 1073656T3 DK 99947037 T DK99947037 T DK 99947037T DK 99947037 T DK99947037 T DK 99947037T DK 1073656 T3 DK1073656 T3 DK 1073656T3
Authority
DK
Denmark
Prior art keywords
gastric acid
acid secretion
imidazopyridine derivatives
inhibit gastric
inhibit
Prior art date
Application number
DK99947037T
Other languages
Danish (da)
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Ingemar Starke
Peter Nordberg
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1073656T3 publication Critical patent/DK1073656T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99947037T 1998-04-29 1999-04-23 Imidazopyridinderivater, der inhiberer mavesyresecernering DK1073656T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds

Publications (1)

Publication Number Publication Date
DK1073656T3 true DK1073656T3 (da) 2006-01-16

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
DK99947037T DK1073656T3 (da) 1998-04-29 1999-04-23 Imidazopyridinderivater, der inhiberer mavesyresecernering
DK99947038T DK1073657T3 (da) 1998-04-29 1999-04-23 Imidazopyridinderivater, der inhiberer mavesyresekretion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK99947038T DK1073657T3 (da) 1998-04-29 1999-04-23 Imidazopyridinderivater, der inhiberer mavesyresekretion

Country Status (34)

Country Link
US (2) US6313137B1 (sk)
EP (4) EP1073657B1 (sk)
JP (2) JP3692034B2 (sk)
KR (3) KR100595805B1 (sk)
CN (2) CN1165535C (sk)
AR (2) AR015768A1 (sk)
AT (4) ATE312101T1 (sk)
AU (2) AU769190B2 (sk)
BR (2) BR9909995B1 (sk)
CA (2) CA2329921A1 (sk)
CZ (2) CZ292567B6 (sk)
DE (4) DE69928792T2 (sk)
DK (2) DK1073656T3 (sk)
EE (2) EE04916B1 (sk)
ES (2) ES2252975T3 (sk)
HK (5) HK1033457A1 (sk)
HU (2) HUP0102313A3 (sk)
ID (2) ID26819A (sk)
IL (4) IL139297A0 (sk)
IS (2) IS5683A (sk)
MY (2) MY121379A (sk)
NO (2) NO318203B1 (sk)
NZ (2) NZ507639A (sk)
PL (2) PL343797A1 (sk)
RU (2) RU2235725C2 (sk)
SA (2) SA99200064B1 (sk)
SE (1) SE9801526D0 (sk)
SI (1) SI1073656T1 (sk)
SK (2) SK285768B6 (sk)
TR (4) TR200003176T2 (sk)
TW (2) TWI250159B (sk)
UA (2) UA66846C2 (sk)
WO (2) WO1999055705A1 (sk)
ZA (2) ZA200005796B (sk)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
WO2002064121A1 (en) * 2001-02-13 2002-08-22 Astrazeneca Ab Novel modified released formulation
SK10982003A3 (sk) * 2001-03-08 2004-02-03 Astrazeneca Ab Nové použitie
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
CA2499639C (en) 2002-09-19 2011-11-08 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
PL375567A1 (en) 2002-11-19 2005-11-28 Altana Pharma Ag 8-substituted imidazopyridines
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
MXPA05009063A (es) * 2003-02-26 2005-12-12 Sugen Inc Compuestos de aminoheteroarilo como inhibidores de proteina cinasa.
RS20050669A (en) 2003-03-10 2008-04-04 Altana Pharma Ag., Novel process for the preparation of roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301904D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005041961A1 (en) * 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2005315303A1 (en) * 2004-12-17 2006-06-22 Pfizer Inc. Chromane derivatives useful as acid pump antagonists
DK1861074T3 (da) 2005-03-16 2013-07-29 Takeda Gmbh Smagsmaskeret doseringsform indeholdende roflumilast
ES2470766T3 (es) * 2005-03-21 2014-06-24 Mei Pharma, Inc. Derivados de [1,2-a]piridina: preparación y aplicaciones farmacéuticas
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
TW200700064A (en) * 2005-03-24 2007-01-01 Glaxo Group Ltd Novel compounds
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
DK1959955T3 (da) * 2005-12-05 2011-02-07 Pfizer Prod Inc Fremgangsmåde til behandling af abnorm cellevækst
CA2632283C (en) 2005-12-05 2011-06-21 Pfizer Products Inc. Polymorphs of a c-met/hgfr inhibitor
JP2009530262A (ja) * 2006-03-17 2009-08-27 ラクオリア創薬株式会社 クロマン誘導体
EP2054036B1 (en) 2006-07-24 2019-12-18 Singh-Broemer and Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (en) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituted imidazopyridine derivates as melanocortin- 4 receptor antagonists
GB2471619B (en) * 2008-03-31 2012-10-31 Council Scient Ind Res Method for the simultaneous preparation of 3-acetoxy-17-acetamdo-16-formyl-androst-5,16-diene and 3-acetoxy-2'-chloro-5-androsteno[17,6-B]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
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KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
WO2019197232A1 (de) 2018-04-10 2019-10-17 Bayer Aktiengesellschaft Verfahren zur herstellung von 2,6-dialkylphenyl-essigsäuren
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
MX2022005305A (es) 2019-11-04 2022-08-16 Cinclus Pharma Holding AB Formulacion oral de x842.
CN118201927A (zh) 2021-11-05 2024-06-14 辛克鲁斯制药控股有限公司(Publ) 戊二酸利那拉赞的盐酸盐的多晶型物
WO2023079093A1 (en) 2021-11-05 2023-05-11 Cinclus Pharma Holding AB (publ) Polymorphs of the mesylate salt of linaprazan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
WO2024149833A1 (en) 2023-01-11 2024-07-18 Cinclus Pharma Holding AB (publ) Polymorphs of the maleic acid salt of linaprazan glurate
WO2024149834A1 (en) 2023-01-11 2024-07-18 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrobromide salt of linaprazan glurate

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Also Published As

Publication number Publication date
ATE372339T1 (de) 2007-09-15
IS5684A (is) 2000-10-25
HUP0102425A3 (en) 2002-12-28
PL343797A1 (en) 2001-09-10
KR20010043134A (ko) 2001-05-25
NZ507638A (en) 2003-10-31
PL343801A1 (en) 2001-09-10
KR100595806B1 (ko) 2006-07-03
AR015768A1 (es) 2001-05-16
ID26819A (id) 2001-02-15
AU769108B2 (en) 2004-01-15
HUP0102313A2 (hu) 2001-12-28
EP1073656A1 (en) 2001-02-07
AU4300799A (en) 1999-11-16
HK1033317A1 (en) 2001-08-24
MY121389A (en) 2006-01-28
HUP0102313A3 (en) 2002-10-28
US6313136B1 (en) 2001-11-06
IL139297A (en) 2007-06-03
SK285768B6 (sk) 2007-07-06
CN1307577A (zh) 2001-08-08
ES2249913T3 (es) 2006-04-01
NO20005451D0 (no) 2000-10-27
CN1174980C (zh) 2004-11-10
TR200102612T2 (tr) 2002-06-21
NZ507639A (en) 2004-01-30
ATE372340T1 (de) 2007-09-15
ZA200005796B (en) 2002-01-18
JP2002513024A (ja) 2002-05-08
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
TR200003176T2 (tr) 2001-03-21
DE69937077D1 (de) 2007-10-18
IL139200A (en) 2010-04-29
DE69928792T2 (de) 2006-07-20
DE69927803T2 (de) 2006-07-06
RU2238271C2 (ru) 2004-10-20
TW490466B (en) 2002-06-11
CZ292567B6 (cs) 2003-10-15
SA99200065B1 (ar) 2006-11-07
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
SA99200065A (ar) 2005-12-03
JP2002513025A (ja) 2002-05-08
DE69927803D1 (de) 2006-03-02
TR200003149T2 (tr) 2001-03-21
CN1306533A (zh) 2001-08-01
SK14912000A3 (sk) 2001-06-11
DE69937077T2 (de) 2008-05-29
CZ20003981A3 (cs) 2001-03-14
CZ293977B6 (cs) 2004-09-15
KR20010043133A (ko) 2001-05-25
EP1073657B1 (en) 2005-12-07
KR100650472B1 (ko) 2006-11-28
ATE307130T1 (de) 2005-11-15
PL195000B1 (pl) 2007-07-31
NO318203B1 (no) 2005-02-14
IS5683A (is) 2000-10-25
NO20005451L (no) 2000-12-27
AR015769A1 (es) 2001-05-16
AU4300699A (en) 1999-11-16
CA2329922C (en) 2006-04-11
CN1165535C (zh) 2004-09-08
EE04676B1 (et) 2006-08-15
AU769190B2 (en) 2004-01-22
SA99200064B1 (ar) 2006-10-11
SK14922000A3 (sk) 2001-06-11
EP1491543A1 (en) 2004-12-29
JP3883383B2 (ja) 2007-02-21
ES2252975T3 (es) 2006-05-16
SE9801526D0 (sv) 1998-04-29
BR9909996B1 (pt) 2010-08-24
HUP0102425A2 (hu) 2001-11-28
HK1036981A1 (en) 2002-01-25
EP1073656B1 (en) 2005-10-19
NO317262B1 (no) 2004-09-27
ZA200005797B (en) 2002-01-18
CA2329921A1 (en) 1999-11-04
TWI250159B (en) 2006-03-01
BR9909996A (pt) 2000-12-26
MY121379A (en) 2006-01-28
DE69937076T2 (de) 2008-05-29
JP3692034B2 (ja) 2005-09-07
IL139200A0 (en) 2001-11-25
US6313137B1 (en) 2001-11-06
TR200102728T2 (tr) 2002-06-21
HK1033457A1 (en) 2001-08-31
ATE312101T1 (de) 2005-12-15
UA66846C2 (uk) 2004-06-15
EP1491542A3 (en) 2005-01-05
KR100595805B1 (ko) 2006-07-03
HK1071139A1 (en) 2005-07-08
WO1999055705A1 (en) 1999-11-04
BR9909995A (pt) 2000-12-26
HK1036984A1 (en) 2002-01-25
DE69937076D1 (de) 2007-10-18
EE04916B1 (et) 2007-10-15
CA2329922A1 (en) 1999-11-04
CZ20003982A3 (cs) 2001-02-14
UA67769C2 (uk) 2004-07-15
EP1073657A1 (en) 2001-02-07
RU2235725C2 (ru) 2004-09-10
WO1999055706A9 (en) 2000-03-16
EP1491543B1 (en) 2007-09-05
DE69928792D1 (de) 2006-01-12
KR20050121760A (ko) 2005-12-27
EE200000626A (et) 2002-04-15
DK1073657T3 (da) 2006-03-13
EP1491542A2 (en) 2004-12-29
BR9909995B1 (pt) 2010-07-13
ID27530A (id) 2001-04-12
IL139297A0 (en) 2001-11-25
NO20005450L (no) 2000-12-22
NO20005450D0 (no) 2000-10-27

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