DE3040978A1 - Vaginalring - Google Patents

Vaginalring

Info

Publication number
DE3040978A1
DE3040978A1 DE19803040978 DE3040978A DE3040978A1 DE 3040978 A1 DE3040978 A1 DE 3040978A1 DE 19803040978 DE19803040978 DE 19803040978 DE 3040978 A DE3040978 A DE 3040978A DE 3040978 A1 DE3040978 A1 DE 3040978A1
Authority
DE
Germany
Prior art keywords
layer
active ingredient
ring
active agent
vaginal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19803040978
Other languages
German (de)
English (en)
Inventor
Hans-Jürgen 1000 Berlin Reck
Fred Windt
Ingfried Dipl.-Biol. Dr. Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to DE19803040978 priority Critical patent/DE3040978A1/de
Priority to AU76709/81A priority patent/AU7670981A/en
Priority to DD81234288A priority patent/DD201645A5/de
Priority to YU02522/81A priority patent/YU252281A/xx
Priority to GR66351A priority patent/GR75367B/el
Priority to EP81108872A priority patent/EP0050867B1/en
Priority to DE8181108872T priority patent/DE3176606D1/de
Priority to AT81108872T priority patent/ATE31875T1/de
Priority to JP56170262A priority patent/JPS5799954A/ja
Priority to DK471481A priority patent/DK151529C/da
Priority to EG81625A priority patent/EG15347A/xx
Priority to ES527301A priority patent/ES527301A0/es
Priority to NO813625A priority patent/NO153753C/no
Priority to IE2503/81A priority patent/IE54581B1/en
Priority to ES1981261058U priority patent/ES261058U/es
Priority to SU813347855A priority patent/SU1440326A3/ru
Priority to HU813156A priority patent/HU183646B/hu
Priority to PT73886A priority patent/PT73886B/pt
Priority to CA000388832A priority patent/CA1165239A/en
Priority to FI813360A priority patent/FI78389C/fi
Priority to ZW260/81A priority patent/ZW26081A1/xx
Priority to BG053982A priority patent/BG42182A3/xx
Priority to ZA817477A priority patent/ZA817477B/xx
Priority to PL1981233606A priority patent/PL127941B1/pl
Priority to CS817905A priority patent/CS253564B2/cs
Priority to IL64139A priority patent/IL64139A/xx
Priority to RO81105663A priority patent/RO88674A/ro
Publication of DE3040978A1 publication Critical patent/DE3040978A1/de
Priority to US07/014,316 priority patent/US4822616A/en
Priority to JP1990014821U priority patent/JPH048893Y2/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Control And Safety Of Cranes (AREA)
DE19803040978 1980-10-28 1980-10-28 Vaginalring Withdrawn DE3040978A1 (de)

Priority Applications (29)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring
AU76709/81A AU7670981A (en) 1980-10-28 1981-10-22 Vaginal ring with uniform active agent release
DD81234288A DD201645A5 (de) 1980-10-28 1981-10-22 Vaginalring
YU02522/81A YU252281A (en) 1980-10-28 1981-10-22 Method of obtaining a vaginal coil
GR66351A GR75367B (en, 2012) 1980-10-28 1981-10-23
EP81108872A EP0050867B1 (en) 1980-10-28 1981-10-24 Vaginal ring
DE8181108872T DE3176606D1 (en) 1980-10-28 1981-10-24 Vaginal ring
AT81108872T ATE31875T1 (de) 1980-10-28 1981-10-24 Anneau vaginal.
JP56170262A JPS5799954A (en) 1980-10-28 1981-10-26 Vagina ring
DK471481A DK151529C (da) 1980-10-28 1981-10-26 Vaginalring med et lag aktivt steroid
SU813347855A SU1440326A3 (ru) 1980-10-28 1981-10-27 Вагинальное кольцо
ES527301A ES527301A0 (es) 1980-10-28 1981-10-27 Procedimiento de fabricacion de anillo vaginales de material sintetico para implantacion en hembras de mamiferos.
NO813625A NO153753C (no) 1980-10-28 1981-10-27 Vaginalring.
IE2503/81A IE54581B1 (en) 1980-10-28 1981-10-27 Vaginal ring
ES1981261058U ES261058U (es) 1980-10-28 1981-10-27 Anillo vaginal
EG81625A EG15347A (en) 1980-10-28 1981-10-27 Vaginal ring
HU813156A HU183646B (en) 1980-10-28 1981-10-27 Vagina ring containing holding ring and coating consists of effective agent
PT73886A PT73886B (fr) 1980-10-28 1981-10-27 Anneau vaginal
CA000388832A CA1165239A (en) 1980-10-28 1981-10-27 Vaginal ring
FI813360A FI78389C (fi) 1980-10-28 1981-10-27 Vaginalring.
BG053982A BG42182A3 (en) 1980-10-28 1981-10-28 Vaginal ring
ZW260/81A ZW26081A1 (en) 1980-10-28 1981-10-28 Vaginal ring
ZA817477A ZA817477B (en) 1980-10-28 1981-10-28 Vaginal ring
PL1981233606A PL127941B1 (en) 1980-10-28 1981-10-28 Intravaginal ring
CS817905A CS253564B2 (en) 1980-10-28 1981-10-28 Vaginal ring
IL64139A IL64139A (en) 1980-10-28 1981-10-28 Vaginal ring
RO81105663A RO88674A (ro) 1980-10-28 1981-10-28 Inel vaginal
US07/014,316 US4822616A (en) 1980-10-28 1987-02-13 Vaginal ring
JP1990014821U JPH048893Y2 (en, 2012) 1980-10-28 1990-02-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (1)

Publication Number Publication Date
DE3040978A1 true DE3040978A1 (de) 1982-05-27

Family

ID=6115593

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19803040978 Withdrawn DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring
DE8181108872T Expired DE3176606D1 (en) 1980-10-28 1981-10-24 Vaginal ring

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8181108872T Expired DE3176606D1 (en) 1980-10-28 1981-10-24 Vaginal ring

Country Status (26)

Country Link
US (1) US4822616A (en, 2012)
EP (1) EP0050867B1 (en, 2012)
JP (2) JPS5799954A (en, 2012)
AT (1) ATE31875T1 (en, 2012)
AU (1) AU7670981A (en, 2012)
BG (1) BG42182A3 (en, 2012)
CA (1) CA1165239A (en, 2012)
CS (1) CS253564B2 (en, 2012)
DD (1) DD201645A5 (en, 2012)
DE (2) DE3040978A1 (en, 2012)
DK (1) DK151529C (en, 2012)
EG (1) EG15347A (en, 2012)
ES (2) ES261058U (en, 2012)
FI (1) FI78389C (en, 2012)
GR (1) GR75367B (en, 2012)
HU (1) HU183646B (en, 2012)
IE (1) IE54581B1 (en, 2012)
IL (1) IL64139A (en, 2012)
NO (1) NO153753C (en, 2012)
PL (1) PL127941B1 (en, 2012)
PT (1) PT73886B (en, 2012)
RO (1) RO88674A (en, 2012)
SU (1) SU1440326A3 (en, 2012)
YU (1) YU252281A (en, 2012)
ZA (1) ZA817477B (en, 2012)
ZW (1) ZW26081A1 (en, 2012)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347125A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
GB8430703D0 (en) * 1984-12-05 1985-01-16 Lrc Products Drug release devices
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US6264638B1 (en) * 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
AU1797592A (en) * 1991-04-12 1992-11-17 Upjohn Company, The Vaginal drug delivery device
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
DK0836473T3 (da) 1995-07-04 2002-02-11 Akzo Nobel Nv Ringformede indretninger
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
IL127880A0 (en) 1996-07-03 1999-10-28 Ultrafem Inc Method and system for manufacturing elastomeric articles
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
JP2002513690A (ja) 1998-05-01 2002-05-14 エフイ−アイ エンタープライジズ,リミティド 制御放出デバイスの射出成形製造方法
JP2004506482A (ja) * 2000-08-24 2004-03-04 コーネル リサーチ ファンデーション インコーポレーテッド 非ホルモン性腟内避妊用具
EP1339312B1 (en) * 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
HUP0401438A3 (en) * 2001-08-31 2008-04-28 Schering Oy Drug delivery system
AU2003278766A1 (en) * 2002-09-04 2004-03-29 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
WO2004096151A2 (en) * 2003-04-29 2004-11-11 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
DE602005015090D1 (de) 2004-03-24 2009-08-06 Organon Nv Arzneimittelabgabesystem auf basis von polyethylen-vinylacetat-copolymeren
WO2006081279A2 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
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TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
EP2359807B1 (en) 2008-02-04 2017-07-26 Ferring B.V. Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
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WO2011140375A1 (en) 2010-05-05 2011-11-10 Diliberti Charles E Methods of reducing symptoms in subjects using single dosage forms with tapering release rates
US8939948B2 (en) 2010-06-01 2015-01-27 Forsight Vision5, Inc. Ocular insert apparatus and methods
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
WO2012121811A1 (en) 2011-03-04 2012-09-13 Arstat, Inc. Treatment of excessive menstrual blood loss by intravaginal administration of low doses of antifibronlytic or hemostatic agent
DE202011110355U1 (de) 2011-03-09 2014-01-15 Arstat, Inc. Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
DE202011110356U1 (de) 2011-03-10 2014-01-15 Arstat, Inc. Behandlung von Endometriose durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
WO2012138542A1 (en) * 2011-04-07 2012-10-11 Arstat, Inc. Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug
CA2838402C (en) * 2011-06-06 2019-12-03 Oak Crest Institute Of Science Drug delivery device employing wicking release window
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
DK2911623T3 (da) 2012-10-26 2019-10-28 Forsight Vision5 Inc Oftalmisk system til langvarig frigivelse af lægemiddel til øjet
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
JP6898856B2 (ja) 2015-05-13 2021-07-07 バイエル・オーイュー 長時間作用型薬物送達装置および避妊におけるその使用
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
DK3432889T3 (da) * 2016-03-23 2022-10-17 Univ North Carolina Chapel Hill Geometrisk komplekse intravaginale ringe, systemer og fremgangsmåder til fremstilling deraf
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
BR112020008231A2 (pt) 2017-10-27 2020-10-27 Renovia, Inc. dispositivos, sistemas e métodos para treinamento dos músculos do assoalho pélvico
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Publication number Priority date Publication date Assignee Title
DE2029828A1 (de) * 1969-06-16 1970-12-23 Michael Reese Hospital and Medical Center, Chicago, 111. (V.St.A.) Vorrichtung zur Schwangerschaftsverhütung
GB1264731A (en, 2012) * 1969-11-10 1972-02-23
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring

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US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device
FR2270899A1 (en) * 1974-05-16 1975-12-12 Groves Harvey Vaginal medicator with long medicament-carrying stem - having anchor to correctly position stem
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
IL48277A (en) * 1974-10-18 1978-03-10 Schering Ag Vaginal ring
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US4215691A (en) * 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
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US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
DE2029828A1 (de) * 1969-06-16 1970-12-23 Michael Reese Hospital and Medical Center, Chicago, 111. (V.St.A.) Vorrichtung zur Schwangerschaftsverhütung
GB1264731A (en, 2012) * 1969-11-10 1972-02-23
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring

Also Published As

Publication number Publication date
PL127941B1 (en) 1983-12-31
IE54581B1 (en) 1989-12-06
IL64139A (en) 1985-07-31
BG42182A3 (en) 1987-10-15
ZA817477B (en) 1982-10-27
JPH0324119U (en, 2012) 1991-03-13
PT73886B (fr) 1983-01-25
NO813625L (no) 1982-04-29
CS253564B2 (en) 1987-11-12
ES261058U (es) 1982-05-01
PL233606A1 (en, 2012) 1982-06-21
ES8505538A1 (es) 1985-06-16
EP0050867B1 (en) 1988-01-13
ZW26081A1 (en) 1982-05-19
RO88674A (ro) 1986-06-30
DE3176606D1 (en) 1988-02-18
DK471481A (da) 1982-04-29
FI813360L (fi) 1982-04-29
IE812503L (en) 1982-04-28
JPH048893Y2 (en, 2012) 1992-03-05
EP0050867A1 (en) 1982-05-05
ATE31875T1 (de) 1988-01-15
DK151529B (da) 1987-12-14
FI78389B (fi) 1989-04-28
NO153753C (no) 1986-05-21
JPS5799954A (en) 1982-06-21
CA1165239A (en) 1984-04-10
GR75367B (en, 2012) 1984-07-13
IL64139A0 (en) 1982-01-31
US4822616A (en) 1989-04-18
NO153753B (no) 1986-02-10
EG15347A (en) 1986-03-31
PT73886A (fr) 1981-11-01
DK151529C (da) 1988-05-30
DD201645A5 (de) 1983-08-03
HU183646B (en) 1984-05-28
SU1440326A3 (ru) 1988-11-23
FI78389C (fi) 1989-08-10
YU252281A (en) 1984-04-30
ES527301A0 (es) 1985-06-16
AU7670981A (en) 1982-05-06

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