GR75367B - - Google Patents

Info

Publication number
GR75367B
GR75367B GR66351A GR810166351A GR75367B GR 75367 B GR75367 B GR 75367B GR 66351 A GR66351 A GR 66351A GR 810166351 A GR810166351 A GR 810166351A GR 75367 B GR75367 B GR 75367B
Authority
GR
Greece
Prior art keywords
layer
active agent
free
supporting ring
active
Prior art date
Application number
GR66351A
Other languages
English (en)
Inventor
Ingfried Dr Zimmermann
Fred Windt
Hans-Jurgen Reck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of GR75367B publication Critical patent/GR75367B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Control And Safety Of Cranes (AREA)
  • General Induction Heating (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
GR66351A 1980-10-28 1981-10-23 GR75367B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (1)

Publication Number Publication Date
GR75367B true GR75367B (el) 1984-07-13

Family

ID=6115593

Family Applications (1)

Application Number Title Priority Date Filing Date
GR66351A GR75367B (el) 1980-10-28 1981-10-23

Country Status (26)

Country Link
US (1) US4822616A (el)
EP (1) EP0050867B1 (el)
JP (2) JPS5799954A (el)
AT (1) ATE31875T1 (el)
AU (1) AU7670981A (el)
BG (1) BG42182A3 (el)
CA (1) CA1165239A (el)
CS (1) CS253564B2 (el)
DD (1) DD201645A5 (el)
DE (2) DE3040978A1 (el)
DK (1) DK151529C (el)
EG (1) EG15347A (el)
ES (2) ES261058U (el)
FI (1) FI78389C (el)
GR (1) GR75367B (el)
HU (1) HU183646B (el)
IE (1) IE54581B1 (el)
IL (1) IL64139A (el)
NO (1) NO153753C (el)
PL (1) PL127941B1 (el)
PT (1) PT73886B (el)
RO (1) RO88674A (el)
SU (1) SU1440326A3 (el)
YU (1) YU252281A (el)
ZA (1) ZA817477B (el)
ZW (1) ZW26081A1 (el)

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US6264638B1 (en) 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
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WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device
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GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
ATE207736T1 (de) * 1995-07-04 2001-11-15 Akzo Nobel Nv Ringförmige vorrichtung
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
JP4303788B2 (ja) 1996-07-03 2009-07-29 ウルトラフェム インコーポレイテッド エラストマ物品を製造する方法およびシステム
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
CA2331132C (en) 1998-05-01 2008-12-16 Fei Enterprises, Ltd. Method for injection molding manufacture of controlled release devices
WO2002015832A1 (en) * 2000-08-24 2002-02-28 Cornell Research Foundation, Inc. Non-hormonal vaginal contraceptive
US7226442B2 (en) * 2000-10-10 2007-06-05 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
WO2003017971A1 (en) * 2001-08-31 2003-03-06 Schering Oy Drug delivery system
US7497855B2 (en) * 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
ATE461681T1 (de) * 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
EP1732520B1 (en) 2004-03-24 2009-06-24 N.V. Organon Drug delivery system based on polyethylene vinylacetate copolymers
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
AU2006208131A1 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) * 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
AR066166A1 (es) 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
NZ587758A (en) 2008-02-04 2012-05-25 Teva Womens Health Inc Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
WO2010141729A1 (en) 2009-06-03 2010-12-09 Forsight Labs, Llc Anterior segment drug delivery
EP2456421B1 (en) 2009-07-21 2017-04-05 The Population Council, Inc. Multi-layered gradient vaginal ring
WO2011140375A1 (en) 2010-05-05 2011-11-10 Diliberti Charles E Methods of reducing symptoms in subjects using single dosage forms with tapering release rates
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE202012012713U1 (de) 2011-03-04 2014-01-23 Arstat, Inc. Intravaginale Arzneimittelabgabevorrichtung
DE202011110355U1 (de) 2011-03-09 2014-01-15 Arstat, Inc. Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
DE202011110356U1 (de) 2011-03-10 2014-01-15 Arstat, Inc. Behandlung von Endometriose durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
WO2012138542A1 (en) * 2011-04-07 2012-10-11 Arstat, Inc. Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug
CN103747765B (zh) * 2011-06-06 2016-04-06 橡冠科学研究院 采用芯吸释放窗口的药物递送装置
EP2755615B1 (en) 2011-09-14 2022-04-06 Forsight Vision5, Inc. Ocular insert apparatus
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
DK2911623T3 (da) 2012-10-26 2019-10-28 Forsight Vision5 Inc Oftalmisk system til langvarig frigivelse af lægemiddel til øjet
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
MX2016014281A (es) 2014-05-22 2017-02-22 Therapeuticsmd Inc Formulaciones y terapias de reemplazo de combinación de hormonas naturales.
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
JP6898856B2 (ja) 2015-05-13 2021-07-07 バイエル・オーイュー 長時間作用型薬物送達装置および避妊におけるその使用
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017165624A1 (en) * 2016-03-23 2017-09-28 The University Of North Carolina At Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
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DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
EP3700477A4 (en) 2017-10-27 2021-08-04 Renovia Inc. DEVICES, SYSTEMS AND METHODS FOR TRAINING THE PELVIC FLOOR MUSCLES
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Also Published As

Publication number Publication date
DE3040978A1 (de) 1982-05-27
ZA817477B (en) 1982-10-27
CS253564B2 (en) 1987-11-12
ZW26081A1 (en) 1982-05-19
PL127941B1 (en) 1983-12-31
ES8505538A1 (es) 1985-06-16
IL64139A0 (en) 1982-01-31
EG15347A (en) 1986-03-31
IL64139A (en) 1985-07-31
EP0050867A1 (en) 1982-05-05
PT73886A (fr) 1981-11-01
ES527301A0 (es) 1985-06-16
BG42182A3 (en) 1987-10-15
DK151529C (da) 1988-05-30
JPH048893Y2 (el) 1992-03-05
FI78389C (fi) 1989-08-10
FI813360L (fi) 1982-04-29
ATE31875T1 (de) 1988-01-15
PT73886B (fr) 1983-01-25
CA1165239A (en) 1984-04-10
PL233606A1 (el) 1982-06-21
IE54581B1 (en) 1989-12-06
NO153753B (no) 1986-02-10
EP0050867B1 (en) 1988-01-13
SU1440326A3 (ru) 1988-11-23
DE3176606D1 (en) 1988-02-18
DK471481A (da) 1982-04-29
JPH0324119U (el) 1991-03-13
HU183646B (en) 1984-05-28
ES261058U (es) 1982-05-01
DD201645A5 (de) 1983-08-03
NO813625L (no) 1982-04-29
DK151529B (da) 1987-12-14
YU252281A (en) 1984-04-30
RO88674A (ro) 1986-06-30
AU7670981A (en) 1982-05-06
NO153753C (no) 1986-05-21
JPS5799954A (en) 1982-06-21
IE812503L (en) 1982-04-28
FI78389B (fi) 1989-04-28
US4822616A (en) 1989-04-18

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