ES8505538A1 - Procedimiento de fabricacion de anillo vaginales de material sintetico para implantacion en hembras de mamiferos. - Google Patents

Procedimiento de fabricacion de anillo vaginales de material sintetico para implantacion en hembras de mamiferos.

Info

Publication number
ES8505538A1
ES8505538A1 ES527301A ES527301A ES8505538A1 ES 8505538 A1 ES8505538 A1 ES 8505538A1 ES 527301 A ES527301 A ES 527301A ES 527301 A ES527301 A ES 527301A ES 8505538 A1 ES8505538 A1 ES 8505538A1
Authority
ES
Spain
Prior art keywords
layer
active agent
free
vaginal ring
supporting ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527301A
Other languages
English (en)
Other versions
ES527301A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of ES527301A0 publication Critical patent/ES527301A0/es
Publication of ES8505538A1 publication Critical patent/ES8505538A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Control And Safety Of Cranes (AREA)
  • General Induction Heating (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

PROCEDIMIENTO PARA LA FABRICACION DE ANILLOS VAGINALES DE MATERIAL SINTETICO PARA SU IMPLANTACION EN HEMBRAS DE MAMIFEROS.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE FORMA UN ANILLO DE SOPORTE DE MATERIAL SINTETICO FISIOLOGICAMENTE INOCUO Y EXENTO DE SUSTANCIA ACTIVA; SEGUNDA, SE APLICA SOBRE EL ANILLO FORMADO UNA CAPA DE REVESTIMIENTO QUE CONTIENE UNA SUSTANCIA ACTIVA ESTEROIDICA; Y POR ULTIMO, SE APLICA POR ROCIADO O INMERSION, SOBRE DICHA CAPA DE REVESTIMIENTO, UNA SEGUNDA CAPA EXENTA DE SUSTANCIA ACTIVA, CON UN ESPESOR DE 10 A 1.000 MICRAS.
ES527301A 1980-10-28 1981-10-27 Procedimiento de fabricacion de anillo vaginales de material sintetico para implantacion en hembras de mamiferos. Expired ES8505538A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (2)

Publication Number Publication Date
ES527301A0 ES527301A0 (es) 1985-06-16
ES8505538A1 true ES8505538A1 (es) 1985-06-16

Family

ID=6115593

Family Applications (2)

Application Number Title Priority Date Filing Date
ES527301A Expired ES8505538A1 (es) 1980-10-28 1981-10-27 Procedimiento de fabricacion de anillo vaginales de material sintetico para implantacion en hembras de mamiferos.
ES1981261058U Pending ES261058U (es) 1980-10-28 1981-10-27 Anillo vaginal

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES1981261058U Pending ES261058U (es) 1980-10-28 1981-10-27 Anillo vaginal

Country Status (26)

Country Link
US (1) US4822616A (es)
EP (1) EP0050867B1 (es)
JP (2) JPS5799954A (es)
AT (1) ATE31875T1 (es)
AU (1) AU7670981A (es)
BG (1) BG42182A3 (es)
CA (1) CA1165239A (es)
CS (1) CS253564B2 (es)
DD (1) DD201645A5 (es)
DE (2) DE3040978A1 (es)
DK (1) DK151529C (es)
EG (1) EG15347A (es)
ES (2) ES8505538A1 (es)
FI (1) FI78389C (es)
GR (1) GR75367B (es)
HU (1) HU183646B (es)
IE (1) IE54581B1 (es)
IL (1) IL64139A (es)
NO (1) NO153753C (es)
PL (1) PL127941B1 (es)
PT (1) PT73886B (es)
RO (1) RO88674A (es)
SU (1) SU1440326A3 (es)
YU (1) YU252281A (es)
ZA (1) ZA817477B (es)
ZW (1) ZW26081A1 (es)

Families Citing this family (75)

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DE3347125A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
GB8430703D0 (en) * 1984-12-05 1985-01-16 Lrc Products Drug release devices
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US6264638B1 (en) * 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
AU1797592A (en) * 1991-04-12 1992-11-17 Upjohn Company, The Vaginal drug delivery device
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
ES2166894T3 (es) 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
WO1998000184A1 (en) 1996-07-03 1998-01-08 Ultrafem, Inc. Method and system for manufacturing elastomeric articles
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
TW358031B (en) * 1997-04-11 1999-05-11 Akze Nobel N V Drug delivery system for 2 or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
ATE313422T1 (de) * 1998-05-01 2006-01-15 Duramed Pharmaceuticals Inc Verfahren zur spritzgussherstellung von vorrichtungen mit kontrollierter wirkstofffreisetzung und damit hergestellte vorrichtung
EP1313422B1 (en) * 2000-08-24 2010-01-20 Sidney Lerner Non-hormonal vaginal contraceptive
AU2002211629A1 (en) * 2000-10-10 2002-04-22 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
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US7497855B2 (en) * 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
WO2004096151A2 (en) * 2003-04-29 2004-11-11 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
DE602005015090D1 (de) 2004-03-24 2009-08-06 Organon Nv Arzneimittelabgabesystem auf basis von polyethylen-vinylacetat-copolymeren
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
EP1843783B1 (en) * 2005-01-25 2012-05-30 MicroCHIPS, Inc. Control of drug release by transient modification of local microenvironments
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
US8741329B2 (en) 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
MX337634B (es) 2008-02-04 2016-03-14 Teva Womens Health Inc Anillos intravaginales monoliticos que comprenden progesterona y metodos de manufactura y uso de los mismos.
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
CN102596097B (zh) 2009-06-03 2015-05-20 弗赛特实验室有限责任公司 一种眼插入件
CA2767967C (en) 2009-07-21 2014-10-21 The Population Council, Inc. Multi-layered gradient vaginal ring
EA201290972A1 (ru) 2010-05-05 2013-08-30 Тева Вимен'С Хелс, Инк. Способы уменьшения симптомов у субъектов с применением лекарственных форм для однократного введения с постепенно снижающимися скоростями высвобождения
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
WO2012121811A1 (en) 2011-03-04 2012-09-13 Arstat, Inc. Treatment of excessive menstrual blood loss by intravaginal administration of low doses of antifibronlytic or hemostatic agent
WO2012121767A1 (en) 2011-03-09 2012-09-13 Arstat, Inc. Treatment of uterine fibroids by intravaginal administration of a low dose of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
WO2012121778A1 (en) 2011-03-10 2012-09-13 Arstat, Inc. Treatment of endometriosis by intravaginal administration of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
WO2012138542A1 (en) * 2011-04-07 2012-10-11 Arstat, Inc. Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug
CN105853445A (zh) * 2011-06-06 2016-08-17 橡冠科学研究院 采用芯吸释放窗口的药物递送装置
RU2740680C2 (ru) 2011-09-14 2021-01-19 Форсайт Вижн5, Инк. Глазное вкладочное устройство и способы
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
AU2013334169B2 (en) 2012-10-26 2018-03-29 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
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Also Published As

Publication number Publication date
JPH0324119U (es) 1991-03-13
ES527301A0 (es) 1985-06-16
DK151529B (da) 1987-12-14
RO88674A (ro) 1986-06-30
DE3176606D1 (en) 1988-02-18
DK471481A (da) 1982-04-29
CS253564B2 (en) 1987-11-12
EP0050867B1 (en) 1988-01-13
EP0050867A1 (en) 1982-05-05
IE54581B1 (en) 1989-12-06
PT73886B (fr) 1983-01-25
SU1440326A3 (ru) 1988-11-23
FI813360L (fi) 1982-04-29
EG15347A (en) 1986-03-31
NO813625L (no) 1982-04-29
DK151529C (da) 1988-05-30
ZA817477B (en) 1982-10-27
HU183646B (en) 1984-05-28
ES261058U (es) 1982-05-01
GR75367B (es) 1984-07-13
FI78389B (fi) 1989-04-28
IL64139A0 (en) 1982-01-31
IE812503L (en) 1982-04-28
AU7670981A (en) 1982-05-06
YU252281A (en) 1984-04-30
JPH048893Y2 (es) 1992-03-05
PL127941B1 (en) 1983-12-31
DE3040978A1 (de) 1982-05-27
ATE31875T1 (de) 1988-01-15
NO153753B (no) 1986-02-10
US4822616A (en) 1989-04-18
PT73886A (fr) 1981-11-01
IL64139A (en) 1985-07-31
JPS5799954A (en) 1982-06-21
BG42182A3 (en) 1987-10-15
FI78389C (fi) 1989-08-10
DD201645A5 (de) 1983-08-03
NO153753C (no) 1986-05-21
PL233606A1 (es) 1982-06-21
CA1165239A (en) 1984-04-10
ZW26081A1 (en) 1982-05-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020506