RO88674A - Inel vaginal - Google Patents

Inel vaginal

Info

Publication number
RO88674A
RO88674A RO81105663A RO10566381A RO88674A RO 88674 A RO88674 A RO 88674A RO 81105663 A RO81105663 A RO 81105663A RO 10566381 A RO10566381 A RO 10566381A RO 88674 A RO88674 A RO 88674A
Authority
RO
Romania
Prior art keywords
layer
active agent
free
supporting ring
vaginal rings
Prior art date
Application number
RO81105663A
Other languages
English (en)
French (fr)
Inventor
Ingfried Zimmermann
Fred Windt
Hans J Reck
Original Assignee
Schering Ag,Bw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag,Bw filed Critical Schering Ag,Bw
Publication of RO88674A publication Critical patent/RO88674A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Control And Safety Of Cranes (AREA)
RO81105663A 1980-10-28 1981-10-28 Inel vaginal RO88674A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (1)

Publication Number Publication Date
RO88674A true RO88674A (ro) 1986-06-30

Family

ID=6115593

Family Applications (1)

Application Number Title Priority Date Filing Date
RO81105663A RO88674A (ro) 1980-10-28 1981-10-28 Inel vaginal

Country Status (26)

Country Link
US (1) US4822616A (ro)
EP (1) EP0050867B1 (ro)
JP (2) JPS5799954A (ro)
AT (1) ATE31875T1 (ro)
AU (1) AU7670981A (ro)
BG (1) BG42182A3 (ro)
CA (1) CA1165239A (ro)
CS (1) CS253564B2 (ro)
DD (1) DD201645A5 (ro)
DE (2) DE3040978A1 (ro)
DK (1) DK151529C (ro)
EG (1) EG15347A (ro)
ES (2) ES261058U (ro)
FI (1) FI78389C (ro)
GR (1) GR75367B (ro)
HU (1) HU183646B (ro)
IE (1) IE54581B1 (ro)
IL (1) IL64139A (ro)
NO (1) NO153753C (ro)
PL (1) PL127941B1 (ro)
PT (1) PT73886B (ro)
RO (1) RO88674A (ro)
SU (1) SU1440326A3 (ro)
YU (1) YU252281A (ro)
ZA (1) ZA817477B (ro)
ZW (1) ZW26081A1 (ro)

Families Citing this family (76)

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DE3347125A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
GB8430703D0 (en) * 1984-12-05 1985-01-16 Lrc Products Drug release devices
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US6264638B1 (en) 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
DK0836473T3 (da) 1995-07-04 2002-02-11 Akzo Nobel Nv Ringformede indretninger
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US6241846B1 (en) 1996-07-03 2001-06-05 Ultrafem, Inc. Apparatus for manufacturing elastomeric articles
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
WO1999056934A1 (en) 1998-05-01 1999-11-11 Fei Enterprises, Ltd. Method for injection molding manufacture of controlled release devices
AU8672601A (en) 2000-08-24 2002-03-04 Cornell Res Foundation Inc Non-hormonal vaginal contraceptive
EP1339312B1 (en) * 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
CN1289064C (zh) * 2001-08-31 2006-12-13 先灵有限责任公司 药物输送体系
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
JP4898431B2 (ja) * 2003-04-29 2012-03-14 ザ ジェネラル ホスピタル コーポレイション 複数薬物の持続放出のための方法およびデバイス
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
JP2007530500A (ja) 2004-03-24 2007-11-01 ナームローゼ・フエンノートチヤツプ・オルガノン ポリエチレン酢酸ビニル共重合体に基づく薬物送達システム
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
AU2006208131A1 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
AR066166A1 (es) 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
ES2648640T3 (es) 2008-02-04 2018-01-04 Ferring B.V. Anillos intravaginales monolíticos que comprenden progesterona y métodos de fabricación y usos de los mismos
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
EP2437684B1 (en) 2009-06-03 2022-06-15 ForSight Vision5, Inc. Anterior segment drug delivery
AU2010274946B2 (en) 2009-07-21 2013-09-12 The Population Council, Inc. Multi-layered gradient vaginal ring
EA201290972A1 (ru) 2010-05-05 2013-08-30 Тева Вимен'С Хелс, Инк. Способы уменьшения симптомов у субъектов с применением лекарственных форм для однократного введения с постепенно снижающимися скоростями высвобождения
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE202012012713U1 (de) 2011-03-04 2014-01-23 Arstat, Inc. Intravaginale Arzneimittelabgabevorrichtung
DE202011110355U1 (de) 2011-03-09 2014-01-15 Arstat, Inc. Behandlung von Uterusmyomen durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
DE202011110356U1 (de) 2011-03-10 2014-01-15 Arstat, Inc. Behandlung von Endometriose durch intravaginale Verabreichung einer niedrigen Dosis eines selektiven Progesteronrezeptormodulators, eines Antigestagens oder eines Antigestagen-Wirkstoffes
DE202012012761U1 (de) 2011-04-07 2013-10-29 Arstat, Inc. Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust
AU2012268068B2 (en) * 2011-06-06 2016-10-13 Auritec Pharmaceuticals Drug delivery device employing wicking release window
CA2848397C (en) 2011-09-14 2022-04-26 Forsight Vision5, Inc. Ocular insert apparatus and methods
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
WO2014066775A1 (en) 2012-10-26 2014-05-01 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
WO2016180764A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
EP3432889B1 (en) 2016-03-23 2022-08-10 The University of North Carolina at Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
CN111801072A (zh) 2017-10-27 2020-10-20 锐诺维公司 用于训练盆底肌的装置、系统和方法
IL292825B1 (en) * 2019-11-12 2026-06-01 Poly Med Inc Medical devices for preventing pregnancy
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
CA988849A (en) * 1969-06-16 1976-05-11 Antonio Scommegna Anti-fertility device
GB1264731A (ro) * 1969-11-10 1972-02-23
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device
FR2270899A1 (en) * 1974-05-16 1975-12-12 Groves Harvey Vaginal medicator with long medicament-carrying stem - having anchor to correctly position stem
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring
IL48277A (en) * 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
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Also Published As

Publication number Publication date
FI813360L (fi) 1982-04-29
JPH0324119U (ro) 1991-03-13
DE3040978A1 (de) 1982-05-27
AU7670981A (en) 1982-05-06
IE812503L (en) 1982-04-28
ES261058U (es) 1982-05-01
HU183646B (en) 1984-05-28
NO153753B (no) 1986-02-10
JPS5799954A (en) 1982-06-21
DD201645A5 (de) 1983-08-03
FI78389C (fi) 1989-08-10
PL127941B1 (en) 1983-12-31
EG15347A (en) 1986-03-31
SU1440326A3 (ru) 1988-11-23
EP0050867B1 (en) 1988-01-13
JPH048893Y2 (ro) 1992-03-05
ES8505538A1 (es) 1985-06-16
NO153753C (no) 1986-05-21
NO813625L (no) 1982-04-29
CA1165239A (en) 1984-04-10
PT73886A (fr) 1981-11-01
CS253564B2 (en) 1987-11-12
IL64139A0 (en) 1982-01-31
ES527301A0 (es) 1985-06-16
US4822616A (en) 1989-04-18
DK151529B (da) 1987-12-14
GR75367B (ro) 1984-07-13
YU252281A (en) 1984-04-30
PL233606A1 (ro) 1982-06-21
DE3176606D1 (en) 1988-02-18
DK471481A (da) 1982-04-29
ZW26081A1 (en) 1982-05-19
EP0050867A1 (en) 1982-05-05
BG42182A3 (en) 1987-10-15
PT73886B (fr) 1983-01-25
IL64139A (en) 1985-07-31
ATE31875T1 (de) 1988-01-15
IE54581B1 (en) 1989-12-06
DK151529C (da) 1988-05-30
FI78389B (fi) 1989-04-28
ZA817477B (en) 1982-10-27

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