IL64139A - Vaginal ring - Google Patents

Vaginal ring

Info

Publication number
IL64139A
IL64139A IL64139A IL6413981A IL64139A IL 64139 A IL64139 A IL 64139A IL 64139 A IL64139 A IL 64139A IL 6413981 A IL6413981 A IL 6413981A IL 64139 A IL64139 A IL 64139A
Authority
IL
Israel
Prior art keywords
layer
active agent
free
vaginal ring
supporting ring
Prior art date
Application number
IL64139A
Other languages
English (en)
Other versions
IL64139A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL64139A0 publication Critical patent/IL64139A0/xx
Publication of IL64139A publication Critical patent/IL64139A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • General Induction Heating (AREA)
  • Control And Safety Of Cranes (AREA)
IL64139A 1980-10-28 1981-10-28 Vaginal ring IL64139A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803040978 DE3040978A1 (de) 1980-10-28 1980-10-28 Vaginalring

Publications (2)

Publication Number Publication Date
IL64139A0 IL64139A0 (en) 1982-01-31
IL64139A true IL64139A (en) 1985-07-31

Family

ID=6115593

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64139A IL64139A (en) 1980-10-28 1981-10-28 Vaginal ring

Country Status (26)

Country Link
US (1) US4822616A (ro)
EP (1) EP0050867B1 (ro)
JP (2) JPS5799954A (ro)
AT (1) ATE31875T1 (ro)
AU (1) AU7670981A (ro)
BG (1) BG42182A3 (ro)
CA (1) CA1165239A (ro)
CS (1) CS253564B2 (ro)
DD (1) DD201645A5 (ro)
DE (2) DE3040978A1 (ro)
DK (1) DK151529C (ro)
EG (1) EG15347A (ro)
ES (2) ES261058U (ro)
FI (1) FI78389C (ro)
GR (1) GR75367B (ro)
HU (1) HU183646B (ro)
IE (1) IE54581B1 (ro)
IL (1) IL64139A (ro)
NO (1) NO153753C (ro)
PL (1) PL127941B1 (ro)
PT (1) PT73886B (ro)
RO (1) RO88674A (ro)
SU (1) SU1440326A3 (ro)
YU (1) YU252281A (ro)
ZA (1) ZA817477B (ro)
ZW (1) ZW26081A1 (ro)

Families Citing this family (76)

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DE3347125A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption
GB8430703D0 (en) * 1984-12-05 1985-01-16 Lrc Products Drug release devices
FR2618329B1 (fr) * 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US6264638B1 (en) * 1989-12-07 2001-07-24 Ultrafem, Inc. Intravaginal drug delivery system and discharge collection device
US5295984A (en) 1989-12-07 1994-03-22 Ultrafem, Inc. Vaginal discharge collection device and intravaginal drug delivery system
WO1992018101A1 (en) * 1991-04-12 1992-10-29 The Upjohn Company Vaginal drug delivery device
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
WO1997002015A1 (en) * 1995-07-04 1997-01-23 Akzo Nobel N.V. Ring-shaped devices
GB9522403D0 (en) * 1995-11-01 1996-01-03 Hoechst Roussel Ltd Intravaginal drug delivery device
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
BR9715048A (pt) 1996-07-03 2001-01-16 Ultrafem Inc Método e sistema para a manufatura de artigos elastoméricos
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
IL123813A0 (en) * 1997-04-11 1998-10-30 Akzo Nobel Nv Drug delivery system for two or more active substances
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
EP1100669B1 (en) * 1998-05-01 2005-12-21 Duramed Pharmaceuticals, Inc. Method for injection molding manufacture of controlled release devices and controlled release device
DE60141145D1 (ro) 2000-08-24 2010-03-11 Sidney Lerner
EP1339312B1 (en) * 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
EP1427390A1 (en) * 2001-08-31 2004-06-16 Schering Oy Drug delivery system
US7497855B2 (en) * 2002-09-04 2009-03-03 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
US7357046B2 (en) 2002-12-16 2008-04-15 N. V. Organon Method for dissolution testing of a pharmaceutical delivery device
EP1620060B1 (en) * 2003-04-29 2010-03-24 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
TWI336627B (en) 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
BRPI0509146B8 (pt) 2004-03-24 2021-05-25 Merck Sharp & Dohme sistema de liberação de droga, método de fabricação do mesmo, e, uso do sistema de liberação de droga
US7488316B2 (en) * 2005-01-25 2009-02-10 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
CN1899643B (zh) * 2005-07-20 2010-12-29 上海市计划生育科学研究所 含有抗雌激素和抗孕激素复合制剂的阴道环或宫内释药装置及其制药用途
US8399012B2 (en) 2006-04-17 2013-03-19 Kimberly-Clark Worldwide, Inc. Degradable therapeutic delivery device
AR066166A1 (es) 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
DK2359807T3 (en) 2008-02-04 2017-10-16 Ferring Bv Monolithic vaginal rings comprising progesterone and methods of preparation and use thereof
US20100040671A1 (en) * 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
US8419793B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
US8420153B2 (en) * 2008-09-19 2013-04-16 Mentor Worldwide Llc Coating with antimicrobial agents
AU2010256558B2 (en) 2009-06-03 2013-10-03 Forsight Labs, Llc Anterior segment drug delivery
BR112012001353B8 (pt) 2009-07-21 2021-05-25 The Population Council Inc anel vaginal, e, método para fabricar um anel vaginal
CN103154016A (zh) 2010-05-05 2013-06-12 特卫华妇女健康有限公司 使用具有逐渐降低的释放速率的单剂型减轻对象症状的方法
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE202012012713U1 (de) 2011-03-04 2014-01-23 Arstat, Inc. Intravaginale Arzneimittelabgabevorrichtung
WO2012121767A1 (en) 2011-03-09 2012-09-13 Arstat, Inc. Treatment of uterine fibroids by intravaginal administration of a low dose of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
WO2012121778A1 (en) 2011-03-10 2012-09-13 Arstat, Inc. Treatment of endometriosis by intravaginal administration of selective progesterone receptor modulator (sprm), anti-progestin, or anti-progestational agent
DE202012012761U1 (de) 2011-04-07 2013-10-29 Arstat, Inc. Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust
KR102059698B1 (ko) * 2011-06-06 2019-12-26 오크 크레스트 인스티튜트 오브 사이언스 심지 방출창을 도입한 약물 전달 장치
AU2012308317B2 (en) 2011-09-14 2017-01-05 Forsight Vision5, Inc. Ocular insert apparatus and methods
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
SI2911623T1 (sl) 2012-10-26 2019-12-31 Forsight Vision5, Inc. Oftalmični sistem za podaljšano sproščanje zdravila v oko
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
WO2015055789A1 (en) 2013-10-17 2015-04-23 Bayer Pharma Aktiengesellschaft INTRAVAGINAL USE OF 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, INTRAVAGINAL RINGS COMPRISING 18-METHYL-15ß,16ß-METHYLENE-19-NOR-20-SPIROX-4-EN-3-ONES, AND USE THEREOF IN CONTRACEPTION
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
DE102014004388A1 (de) * 2014-03-26 2015-10-01 Angela Kayser Verfahren und System zum intravaginalen Verabreichen von Progesteron
CA2947767A1 (en) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
ES3009909T3 (en) 2015-05-13 2025-03-31 Bayer Oy Long acting drug delivery device in form of an implant or iud comprising levonorgestrel and ethinylestradiol
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
EP4129300A1 (en) 2016-03-23 2023-02-08 The University of North Carolina at Chapel Hill Geometrically complex intravaginal rings, systems and methods of making the same
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
DE102017113166A1 (de) 2017-06-14 2018-12-20 Amw Gmbh Depotform zur Abgabe eines Östrogen-Wirkstoffs
EP3700477B1 (en) 2017-10-27 2025-06-11 Axena Health, Inc. Devices, systems, and methods for training pelvic floor muscles
CA3159767A1 (en) * 2019-11-12 2021-05-20 Poly-Med, Inc. Contraceptive medical devices
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
CA988849A (en) * 1969-06-16 1976-05-11 Antonio Scommegna Anti-fertility device
GB1264731A (ro) * 1969-11-10 1972-02-23
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device
FR2270899A1 (en) * 1974-05-16 1975-12-12 Groves Harvey Vaginal medicator with long medicament-carrying stem - having anchor to correctly position stem
DE2445971A1 (de) * 1974-09-24 1976-04-08 Schering Ag Arzneimittelwirkstofftraeger ii
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
IL48277A (en) * 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US4215691A (en) * 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring

Also Published As

Publication number Publication date
DE3040978A1 (de) 1982-05-27
IE812503L (en) 1982-04-28
US4822616A (en) 1989-04-18
FI813360L (fi) 1982-04-29
ES261058U (es) 1982-05-01
JPH048893Y2 (ro) 1992-03-05
DE3176606D1 (en) 1988-02-18
ES8505538A1 (es) 1985-06-16
IL64139A0 (en) 1982-01-31
EP0050867A1 (en) 1982-05-05
ZA817477B (en) 1982-10-27
PL233606A1 (ro) 1982-06-21
JPH0324119U (ro) 1991-03-13
EP0050867B1 (en) 1988-01-13
BG42182A3 (en) 1987-10-15
GR75367B (ro) 1984-07-13
RO88674A (ro) 1986-06-30
FI78389B (fi) 1989-04-28
DK151529C (da) 1988-05-30
NO153753B (no) 1986-02-10
PL127941B1 (en) 1983-12-31
ATE31875T1 (de) 1988-01-15
NO153753C (no) 1986-05-21
YU252281A (en) 1984-04-30
SU1440326A3 (ru) 1988-11-23
CS253564B2 (en) 1987-11-12
DD201645A5 (de) 1983-08-03
AU7670981A (en) 1982-05-06
EG15347A (en) 1986-03-31
PT73886A (fr) 1981-11-01
IE54581B1 (en) 1989-12-06
CA1165239A (en) 1984-04-10
JPS5799954A (en) 1982-06-21
ZW26081A1 (en) 1982-05-19
DK471481A (da) 1982-04-29
HU183646B (en) 1984-05-28
ES527301A0 (es) 1985-06-16
PT73886B (fr) 1983-01-25
DK151529B (da) 1987-12-14
NO813625L (no) 1982-04-29
FI78389C (fi) 1989-08-10

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