DD238068A5 - Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c - Google Patents

Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c Download PDF

Info

Publication number
DD238068A5
DD238068A5 DD85281515A DD28151585A DD238068A5 DD 238068 A5 DD238068 A5 DD 238068A5 DD 85281515 A DD85281515 A DD 85281515A DD 28151585 A DD28151585 A DD 28151585A DD 238068 A5 DD238068 A5 DD 238068A5
Authority
DD
German Democratic Republic
Prior art keywords
culture
acid
fermentation
medium
hours
Prior art date
Application number
DD85281515A
Other languages
German (de)
English (en)
Inventor
Floyd M Huber
Richard L Pieper
Anthony J Tietz
Tom E Eaton
Lynda M Ford
Otis W Jun Godfrey
Mary L Huber
Milton J Jun Zmijewski
Original Assignee
���@�����@�K@�������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@�����@�K@�������k�� filed Critical ���@�����@�K@�������k��
Publication of DD238068A5 publication Critical patent/DD238068A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treating Waste Gases (AREA)
  • Pyrane Compounds (AREA)
DD85281515A 1984-10-09 1985-10-08 Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c DD238068A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65897984A 1984-10-09 1984-10-09

Publications (1)

Publication Number Publication Date
DD238068A5 true DD238068A5 (de) 1986-08-06

Family

ID=24643546

Family Applications (2)

Application Number Title Priority Date Filing Date
DD85281515A DD238068A5 (de) 1984-10-09 1985-10-08 Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
DD86288284A DD247023A5 (de) 1984-10-09 1986-03-25 Verfahren zur herstellung des cyclopeptidantibiotikumkomplexes a-21978c oder von faktoren hiervon

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD86288284A DD247023A5 (de) 1984-10-09 1986-03-25 Verfahren zur herstellung des cyclopeptidantibiotikumkomplexes a-21978c oder von faktoren hiervon

Country Status (27)

Country Link
EP (1) EP0178152B1 (es)
JP (1) JPH0787796B2 (es)
KR (1) KR890000800B1 (es)
CN (2) CN1013120B (es)
AT (1) ATE67788T1 (es)
AU (2) AU4837785A (es)
BG (1) BG47040A3 (es)
CS (2) CS276983B6 (es)
CY (1) CY1633A (es)
DD (2) DD238068A5 (es)
DE (1) DE3584218D1 (es)
DK (2) DK165416C (es)
EG (1) EG17619A (es)
ES (2) ES8700862A1 (es)
FI (1) FI82075C (es)
GR (1) GR852432B (es)
HK (1) HK24292A (es)
HU (1) HU196845B (es)
IE (1) IE58655B1 (es)
IL (1) IL76608A (es)
NZ (1) NZ213731A (es)
PH (1) PH21217A (es)
PL (1) PL152359B1 (es)
PT (1) PT81265B (es)
SG (1) SG3292G (es)
SU (1) SU1452484A3 (es)
ZA (1) ZA857759B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294990A3 (en) * 1987-06-10 1990-05-09 Eli Lilly And Company Chromatographic purification process
US4930494A (en) * 1988-03-09 1990-06-05 Olympus Optical Co., Ltd. Apparatus for bending an insertion section of an endoscope using a shape memory alloy
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE3832362A1 (de) * 1988-09-23 1990-03-29 Sandoz Ag Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
AU784755B2 (en) 1999-12-15 2006-06-08 Merck Sharp & Dohme Corp. Daptomycin Analogs as antibacterial agents
CN1423656A (zh) 1999-12-15 2003-06-11 卡比斯特制药公司 作为抗菌剂的脂肽
US6696412B1 (en) * 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
RU2512396C2 (ru) 2008-12-22 2014-04-10 Кьюбист Фармасьютикалз, Инк. Новые противобактериальные средства для лечения грамположительных инфекций
US8835382B2 (en) 2009-11-23 2014-09-16 Cubist Pharmaceuticals, Inc. Lipopeptide compositions and related methods
CN103857440B (zh) * 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN107964557B (zh) * 2018-01-17 2020-11-20 自然资源部第三海洋研究所 一种提高芽孢杆菌抗菌脂肽产量的发酵方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production

Also Published As

Publication number Publication date
FI82075B (fi) 1990-09-28
SU1452484A3 (ru) 1989-01-15
CS719885A3 (en) 1992-03-18
ES553603A0 (es) 1987-11-01
AU634766B2 (en) 1993-03-04
KR860003335A (ko) 1986-05-23
FI82075C (fi) 1991-01-10
NZ213731A (en) 1988-04-29
CY1633A (en) 1992-11-06
IL76608A (en) 1991-03-10
DK165757C (da) 1993-06-07
FI853910L (fi) 1986-04-10
CN1013120B (zh) 1991-07-10
PT81265A (en) 1985-11-01
EG17619A (en) 1991-03-30
CS819286A3 (en) 1992-03-18
HU196845B (en) 1989-01-30
PL255683A1 (en) 1986-07-29
ZA857759B (en) 1987-05-27
EP0178152A3 (en) 1988-11-02
GR852432B (es) 1986-02-10
DK165416B (da) 1992-11-23
JPH0787796B2 (ja) 1995-09-27
DK457585A (da) 1986-04-10
KR890000800B1 (ko) 1989-04-07
PL152359B1 (en) 1990-12-31
DE3584218D1 (de) 1991-10-31
DK148791D0 (da) 1991-08-21
EP0178152B1 (en) 1991-09-25
SG3292G (en) 1992-03-20
CN85107552A (zh) 1987-05-20
CN1051200A (zh) 1991-05-08
ATE67788T1 (de) 1991-10-15
DK148791A (da) 1991-08-21
AU4837785A (en) 1986-04-17
AU5375290A (en) 1990-11-01
IL76608A0 (en) 1986-02-28
ES547689A0 (es) 1986-11-16
HUT39782A (en) 1986-10-29
IE58655B1 (en) 1993-11-03
DK165416C (da) 1993-04-05
PH21217A (en) 1987-08-21
FI853910A0 (fi) 1985-10-08
CS276978B6 (en) 1992-11-18
DD247023A5 (de) 1987-06-24
HK24292A (en) 1992-04-10
CS276983B6 (en) 1992-11-18
ES8700862A1 (es) 1986-11-16
ES8800362A1 (es) 1987-11-01
IE852466L (en) 1986-04-09
JPS6192588A (ja) 1986-05-10
DK457585D0 (da) 1985-10-08
DK165757B (da) 1993-01-11
EP0178152A2 (en) 1986-04-16
BG47040A3 (en) 1990-04-16
PT81265B (pt) 1988-02-17

Similar Documents

Publication Publication Date Title
DE3783588T2 (de) Neue verbindungen dc-88a und dc-89a1 und deren herstellungsverfahren.
DE3887820T2 (de) Antibiotika, Benanomicine A und B und Dexylosylbenanomicin B, ihre Herstellung und Verwendung.
DE2532568A1 (de) Aclacinomycine a und b und verfahren zu ihrer herstellung
DD238068A5 (de) Verfahren zur herstellung von derivaten der cyclopeptidantibiotika a-21978 c
DE3873845T2 (de) Antimikrobielles agens, fr 109 615 und seine herstellung.
CH668974A5 (de) Antitumor-antibiotikum.
DE3012565A1 (de) Antitumor-antibakterielle mittel
DE69114252T2 (de) Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid.
DE2638766C2 (de) Antibiotika,Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2029768A1 (de) Anti Tumor Verbindung und ihre Her stellungsverfahren
DE2839668C2 (es)
CH631740A5 (en) Process for the preparation of maytansinol and its derivatives
DE2019838B2 (de) 4-Hydroxy-5(3)-ribofuranosylpyrazol-3(5)-carboxamid und Verfahren zu seiner Herstellung
DE3785868T2 (de) Tierwachstum foerdernde mittel.
DE2660964C2 (es)
CH641492A5 (de) Antibiotische substanz.
DE69206858T2 (de) Verbindung UCA1064-B
DE69023804T2 (de) DC115A-Verbindungen mit antibakterieller und antitumor Wirkung.
EP0304400B1 (de) Phenanthridinderivate, Verfahren zu ihrer Herstellung und Mittel zur Ausführung des Verfahrens
DE3882654T2 (de) Enzymhemmer und Methode zu dessen Herstellung.
DE3881566T2 (de) Antitumor-derivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
DE69423467T2 (de) Verbindung uch9
DE2746252A1 (de) Antibiotikum c-15003 enthaltendes arzneimittel zur behandlung von tumore aufweisenden warmbluetern
DE3782199T2 (de) Biologisch aktive peptide tan-866.
DE2510868C3 (de) Nanaomycin A und Verfahren zur Herstellung der Antibiorica Nanaomycin A und Nanaomycin B

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee