DE69114252T2 - Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid. - Google Patents

Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid.

Info

Publication number
DE69114252T2
DE69114252T2 DE69114252T DE69114252T DE69114252T2 DE 69114252 T2 DE69114252 T2 DE 69114252T2 DE 69114252 T DE69114252 T DE 69114252T DE 69114252 T DE69114252 T DE 69114252T DE 69114252 T2 DE69114252 T2 DE 69114252T2
Authority
DE
Germany
Prior art keywords
antituary
reveromycin
fungicide
agent
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69114252T
Other languages
English (en)
Other versions
DE69114252D1 (de
Inventor
Kiyoshi Isono
Hiroyuki Osada
Hidetoshi Takahashi
Gosei Kawanishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
RIKEN Institute of Physical and Chemical Research
Original Assignee
Snow Brand Milk Products Co Ltd
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd, RIKEN Institute of Physical and Chemical Research filed Critical Snow Brand Milk Products Co Ltd
Application granted granted Critical
Publication of DE69114252D1 publication Critical patent/DE69114252D1/de
Publication of DE69114252T2 publication Critical patent/DE69114252T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69114252T 1990-06-14 1991-06-07 Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid. Expired - Fee Related DE69114252T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2155816A JPH0633271B2 (ja) 1990-06-14 1990-06-14 リベロマイシンａ、その製造法並びに抗腫瘍剤及び抗真菌剤
PCT/JP1991/000772 WO1991019718A1 (fr) 1990-06-14 1991-06-07 Reveromycine a, sa production, ainsi que medicament antitumoral et fongicide

Publications (2)

Publication Number Publication Date
DE69114252D1 DE69114252D1 (de) 1995-12-07
DE69114252T2 true DE69114252T2 (de) 1996-04-11

Family

ID=15614106

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114252T Expired - Fee Related DE69114252T2 (de) 1990-06-14 1991-06-07 Reveromycin-a, herstellung und verwendung als antitumormittel sowie als fungizid.

Country Status (6)

Country Link
US (1) US5322854A (de)
EP (1) EP0491956B1 (de)
JP (1) JPH0633271B2 (de)
CA (1) CA2059632C (de)
DE (1) DE69114252T2 (de)
WO (1) WO1991019718A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707644B1 (fr) * 1993-06-29 1995-09-29 Orstom Bistramides biologiquement actifs, leur préparation et leurs applications biologiques.
US5798381A (en) * 1993-03-08 1998-08-25 Institut Francais De Recherche Scientifique Pour Le Development En Cooperation (Orstom) Biologically active bistramides, process for their production and their applications in therapy
AU4845499A (en) * 1998-06-29 2000-01-17 Parker Hughes Institute Synthetic spiroketal pyranes as potent anti-cancer agents
US6335364B1 (en) 1998-06-29 2002-01-01 Parker Hughes Institute Synthetic spiroketal pyranes as potent anti-cancer agents
US6734207B2 (en) 2001-04-20 2004-05-11 Parker Hughes Institute Cytotoxic compounds
KR100634874B1 (ko) 2004-08-20 2006-10-16 충남대학교산학협력단 신규 미생물 스트렙토마이세스 에스피 ｓｈ09 및 이를이용한 흰가루병을 포함하는 식물진균병 방제방법
EP2615168B1 (de) * 2010-08-31 2017-07-19 Riken Verfahren zur herstellung von reveromycin-a oder einem synthetischen zwischenprodukt davon, verfahren zur herstellung von verbindungen mit einem spiroketalring sowie neuen antineoplastika, fungiziden und therapeutika für knochenerkrankungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032184A (ja) * 1987-12-24 1991-01-08 Nippon Kayaku Co Ltd 新規抗生物質ｎｋ８６―０２７９、その製法及びその用途

Also Published As

Publication number Publication date
EP0491956A4 (en) 1992-07-22
CA2059632C (en) 1996-09-03
JPH0633271B2 (ja) 1994-05-02
US5322854A (en) 1994-06-21
EP0491956B1 (de) 1995-11-02
WO1991019718A1 (fr) 1991-12-26
JPH0449296A (ja) 1992-02-18
CA2059632A1 (en) 1991-12-15
EP0491956A1 (de) 1992-07-01
DE69114252D1 (de) 1995-12-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee