ATE67788T1 - Herstellung von derivaten von a-21978c. - Google Patents

Herstellung von derivaten von a-21978c.

Info

Publication number
ATE67788T1
ATE67788T1 AT85307185T AT85307185T ATE67788T1 AT E67788 T1 ATE67788 T1 AT E67788T1 AT 85307185 T AT85307185 T AT 85307185T AT 85307185 T AT85307185 T AT 85307185T AT E67788 T1 ATE67788 T1 AT E67788T1
Authority
AT
Austria
Prior art keywords
producing
derivatives
preparation
new
alkonoyl
Prior art date
Application number
AT85307185T
Other languages
English (en)
Inventor
Floyd Milton Huber
Richard Louis Pieper
Anthony Joseph Tietz
Tom Edward Eaton
Lynda Maxine Ford
Otis Webster Godfrey Jr
Mary Louise Braun Huber
Milton Joseph Zmijewski Jr
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE67788T1 publication Critical patent/ATE67788T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
AT85307185T 1984-10-09 1985-10-08 Herstellung von derivaten von a-21978c. ATE67788T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65897984A 1984-10-09 1984-10-09
EP85307185A EP0178152B1 (de) 1984-10-09 1985-10-08 Herstellung von Derivaten von A-21978C

Publications (1)

Publication Number Publication Date
ATE67788T1 true ATE67788T1 (de) 1991-10-15

Family

ID=24643546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85307185T ATE67788T1 (de) 1984-10-09 1985-10-08 Herstellung von derivaten von a-21978c.

Country Status (27)

Country Link
EP (1) EP0178152B1 (de)
JP (1) JPH0787796B2 (de)
KR (1) KR890000800B1 (de)
CN (2) CN1051200A (de)
AT (1) ATE67788T1 (de)
AU (2) AU4837785A (de)
BG (1) BG47040A3 (de)
CS (2) CS276978B6 (de)
CY (1) CY1633A (de)
DD (2) DD238068A5 (de)
DE (1) DE3584218D1 (de)
DK (2) DK165416C (de)
EG (1) EG17619A (de)
ES (2) ES8700862A1 (de)
FI (1) FI82075C (de)
GR (1) GR852432B (de)
HK (1) HK24292A (de)
HU (1) HU196845B (de)
IE (1) IE58655B1 (de)
IL (1) IL76608A (de)
NZ (1) NZ213731A (de)
PH (1) PH21217A (de)
PL (1) PL152359B1 (de)
PT (1) PT81265B (de)
SG (1) SG3292G (de)
SU (1) SU1452484A3 (de)
ZA (1) ZA857759B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294990A3 (de) * 1987-06-10 1990-05-09 Eli Lilly And Company Chromatographisches Reinigungsverfahren
US4930494A (en) * 1988-03-09 1990-06-05 Olympus Optical Co., Ltd. Apparatus for bending an insertion section of an endoscope using a shape memory alloy
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE3832362A1 (de) * 1988-09-23 1990-03-29 Sandoz Ag Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
EP1240181A2 (de) 1999-12-15 2002-09-18 Cubist Pharmaceuticals, Inc. Daptomycin analoge und deren verwendung als antibakterielle verbindungen
EP1246838A1 (de) 1999-12-15 2002-10-09 Cubist Pharmaceuticals, Inc. Lipopeptide als antibacterielle verbindungen
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
WO2010075215A1 (en) 2008-12-22 2010-07-01 Cubist Pharmaceuticals, Inc. Novel antibacterial agents for the treatment of gram positive infections
SI2504353T2 (sl) 2009-11-23 2023-11-30 Cubist Pharmaceuticals Llc Lipopeptidni sestavki in s tem povezane metode
CN103857440B (zh) 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN107964557B (zh) * 2018-01-17 2020-11-20 自然资源部第三海洋研究所 一种提高芽孢杆菌抗菌脂肽产量的发酵方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production

Also Published As

Publication number Publication date
FI853910A0 (fi) 1985-10-08
JPH0787796B2 (ja) 1995-09-27
DK457585A (da) 1986-04-10
PL152359B1 (en) 1990-12-31
AU4837785A (en) 1986-04-17
DK148791A (da) 1991-08-21
CN1013120B (zh) 1991-07-10
IL76608A (en) 1991-03-10
DK165416B (da) 1992-11-23
DD247023A5 (de) 1987-06-24
FI82075C (fi) 1991-01-10
DK148791D0 (da) 1991-08-21
IL76608A0 (en) 1986-02-28
CN1051200A (zh) 1991-05-08
JPS6192588A (ja) 1986-05-10
PT81265A (en) 1985-11-01
ES8700862A1 (es) 1986-11-16
ES553603A0 (es) 1987-11-01
EP0178152A2 (de) 1986-04-16
FI82075B (fi) 1990-09-28
CS276983B6 (en) 1992-11-18
NZ213731A (en) 1988-04-29
AU5375290A (en) 1990-11-01
CY1633A (en) 1992-11-06
EP0178152A3 (en) 1988-11-02
CN85107552A (zh) 1987-05-20
DE3584218D1 (de) 1991-10-31
PL255683A1 (en) 1986-07-29
DK457585D0 (da) 1985-10-08
GR852432B (de) 1986-02-10
ES547689A0 (es) 1986-11-16
BG47040A3 (en) 1990-04-16
CS719885A3 (en) 1992-03-18
EP0178152B1 (de) 1991-09-25
HUT39782A (en) 1986-10-29
DK165416C (da) 1993-04-05
DK165757B (da) 1993-01-11
EG17619A (en) 1991-03-30
IE58655B1 (en) 1993-11-03
SG3292G (en) 1992-03-20
ES8800362A1 (es) 1987-11-01
DD238068A5 (de) 1986-08-06
HU196845B (en) 1989-01-30
KR860003335A (ko) 1986-05-23
DK165757C (da) 1993-06-07
SU1452484A3 (ru) 1989-01-15
HK24292A (en) 1992-04-10
IE852466L (en) 1986-04-09
CS819286A3 (en) 1992-03-18
FI853910L (fi) 1986-04-10
PH21217A (en) 1987-08-21
ZA857759B (en) 1987-05-27
AU634766B2 (en) 1993-03-04
CS276978B6 (en) 1992-11-18
PT81265B (pt) 1988-02-17
KR890000800B1 (ko) 1989-04-07

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time