DD107670B3 - Verfahren zur herstellung von (3.4-dihydroxy-n-)3-(4-hydroxyphenyl)-1-methyl-n-propyl/-beta-phenethyl-amin - Google Patents

Verfahren zur herstellung von (3.4-dihydroxy-n-)3-(4-hydroxyphenyl)-1-methyl-n-propyl/-beta-phenethyl-amin Download PDF

Info

Publication number
DD107670B3
DD107670B3 DD73170118A DD17011873A DD107670B3 DD 107670 B3 DD107670 B3 DD 107670B3 DD 73170118 A DD73170118 A DD 73170118A DD 17011873 A DD17011873 A DD 17011873A DD 107670 B3 DD107670 B3 DD 107670B3
Authority
DD
German Democratic Republic
Prior art keywords
compound
amine
propyl
methyl
heart
Prior art date
Application number
DD73170118A
Other languages
German (de)
English (en)
Other versions
DD107670A5 (de
Inventor
Ronald R Tuttle
Jack Mills
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22918877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD107670(B3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD107670A5 publication Critical patent/DD107670A5/xx
Publication of DD107670B3 publication Critical patent/DD107670B3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD73170118A 1972-04-12 1973-04-12 Verfahren zur herstellung von (3.4-dihydroxy-n-)3-(4-hydroxyphenyl)-1-methyl-n-propyl/-beta-phenethyl-amin DD107670B3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24346672A 1972-04-12 1972-04-12

Publications (2)

Publication Number Publication Date
DD107670A5 DD107670A5 (de) 1974-08-12
DD107670B3 true DD107670B3 (de) 1988-04-06

Family

ID=22918877

Family Applications (1)

Application Number Title Priority Date Filing Date
DD73170118A DD107670B3 (de) 1972-04-12 1973-04-12 Verfahren zur herstellung von (3.4-dihydroxy-n-)3-(4-hydroxyphenyl)-1-methyl-n-propyl/-beta-phenethyl-amin

Country Status (31)

Country Link
JP (2) JPS5825656B2 (nl)
KR (1) KR790000113B1 (nl)
AR (1) AR203822A1 (nl)
AT (1) AT323719B (nl)
AU (1) AU472734B2 (nl)
BE (1) BE798051A (nl)
BG (1) BG23001A3 (nl)
CA (1) CA1018188A (nl)
CH (2) CH569691A5 (nl)
CS (2) CS190448B2 (nl)
CY (1) CY963A (nl)
DD (1) DD107670B3 (nl)
DE (1) DE2317710C2 (nl)
DK (1) DK142750C (nl)
ES (1) ES413639A1 (nl)
FR (1) FR2182947B1 (nl)
GB (1) GB1392674A (nl)
HK (1) HK50178A (nl)
HU (2) HU167597B (nl)
IE (1) IE37511B1 (nl)
IL (1) IL42016A (nl)
KE (1) KE2870A (nl)
MY (1) MY7800381A (nl)
NL (1) NL174459C (nl)
PH (1) PH11041A (nl)
PL (2) PL90695B1 (nl)
RO (2) RO65105A (nl)
SE (1) SE399064B (nl)
SU (1) SU496719A3 (nl)
YU (2) YU36483B (nl)
ZA (1) ZA732136B (nl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH585693A5 (nl) * 1974-02-08 1977-03-15 Ciba Geigy Ag
US4342692A (en) * 1980-10-20 1982-08-03 Usv Pharmaceutical Corporation Pyrrolidines
ZA825227B (en) * 1981-07-22 1984-03-28 Syntex Inc Substituted pyrrolidine cardiovascular system regulators antihypertensives
JPS6061523A (ja) * 1983-09-16 1985-04-09 Shionogi & Co Ltd 経口用ドブタミン製剤
IL85438A0 (en) * 1987-02-24 1988-07-31 Lilly Co Eli Improvements in or relating to dobutamine salts
JPH0383364U (nl) * 1989-12-18 1991-08-23
AU658188B2 (en) * 1991-05-20 1995-04-06 Tsumura & Co. Phellodendrine analogs and allergy type IV suppressor containing the same as active ingredient
EP0620208B1 (en) * 1993-04-13 1997-07-09 Duphar International Research B.V Production of dobutamine compounds
DE69404063T2 (de) * 1993-04-13 1998-01-22 Duphar Int Res Herstellung von Dobutamin Verbindungen
PT1546088E (pt) 2002-10-03 2015-03-16 Novaremed Ltd Compostos para utilização no tratamento de doenças auto-imunes, de doenças imuno-alérgicas e de rejeição de órgãos ou tecidos transplantados
US7674829B2 (en) 2004-03-26 2010-03-09 Novaremed Limited Compounds for the treatment of AIDS and other viral diseases
GB0804213D0 (en) 2008-03-06 2008-04-16 New Era Biotech Ltd A method of printing or preventing pain
JP2013501006A (ja) 2009-07-31 2013-01-10 コグニション セラピューティクス インク． 認知機能低下の阻害剤
US8802734B2 (en) 2009-09-09 2014-08-12 Novaremed Limited Method of treating or preventing pain
BR112014004414A2 (pt) * 2011-08-25 2017-03-28 Cognition Therapeutics Inc composições e métodos para tratar doença neurodegenerativa
BR112016017808B1 (pt) 2014-01-31 2022-07-12 Cognition Therapeutics, Inc Composto ou sal farmaceuticamente aceitável, uso de um composto e composição para a inibição de um efeito betaamilóide numa célula neuronal
KR102614814B1 (ko) 2017-05-15 2023-12-20 카그니션 테라퓨틱스, 인코퍼레이티드 신경변성 질환 치료용 조성물
CN114524734B (zh) * 2021-12-27 2024-04-26 嘉实（湖南）医药科技有限公司 一种盐酸多巴酚丁胺的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276619A (en) * 1942-03-17 N-phentlaliphatic-dihtoroxyphentnl

Also Published As

Publication number Publication date
YU36483B (en) 1984-02-29
AR203822A1 (es) 1975-10-31
CA1018188A (en) 1977-09-27
IL42016A (en) 1976-05-31
YU97673A (en) 1982-02-25
IE37511B1 (en) 1977-08-03
BG23001A3 (bg) 1977-05-20
DE2317710C2 (de) 1983-08-04
PL94207B1 (nl) 1977-07-30
ZA732136B (en) 1974-03-27
CH580563A5 (nl) 1976-10-15
HU166213B (nl) 1975-02-28
AU5438573A (en) 1974-10-17
DK142750C (da) 1981-08-17
YU37113B (en) 1984-08-31
NL7305097A (nl) 1973-10-16
DD107670A5 (de) 1974-08-12
JPS5825656B2 (ja) 1983-05-28
FR2182947A1 (nl) 1973-12-14
RO65105A (ro) 1980-01-15
CH569691A5 (nl) 1975-11-28
KR790000113B1 (en) 1979-03-20
JPS58131945A (ja) 1983-08-06
CY963A (en) 1978-12-22
SU496719A3 (ru) 1975-12-25
BE798051A (fr) 1973-10-11
AU472734B2 (en) 1976-06-03
SE399064B (sv) 1978-01-30
PH11041A (en) 1977-10-25
DE2317710A1 (de) 1973-10-18
HU167597B (nl) 1975-11-28
GB1392674A (en) 1975-04-30
HK50178A (en) 1978-09-15
DK142750B (da) 1981-01-12
IL42016A0 (en) 1973-06-29
JPS497237A (nl) 1974-01-22
NL174459C (nl) 1984-06-18
CS190406B2 (en) 1979-05-31
KE2870A (en) 1978-09-01
YU321279A (en) 1983-04-27
FR2182947B1 (nl) 1976-07-02
AT323719B (de) 1975-07-25
NL174459B (nl) 1984-01-16
PL90695B1 (nl) 1977-01-31
JPS6221343B2 (nl) 1987-05-12
RO70892A (ro) 1982-02-26
CS190448B2 (en) 1979-05-31
MY7800381A (en) 1978-12-31
ES413639A1 (es) 1976-01-16

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