CO6551686A2 - Inmunoglobinas con dominio variable dual y usos de las mismas - Google Patents
Inmunoglobinas con dominio variable dual y usos de las mismasInfo
- Publication number
- CO6551686A2 CO6551686A2 CO12081792A CO12081792A CO6551686A2 CO 6551686 A2 CO6551686 A2 CO 6551686A2 CO 12081792 A CO12081792 A CO 12081792A CO 12081792 A CO12081792 A CO 12081792A CO 6551686 A2 CO6551686 A2 CO 6551686A2
- Authority
- CO
- Colombia
- Prior art keywords
- immunoglobins
- same
- variable domain
- binding proteins
- dual variable
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
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- Neurology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
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- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
Abstract
Proteínas de unión multivalentes y multiespecíficas modificadas, métodos para elaborarlas y, específicamente, sus usos en la prevención, el diagnóstico y/o el tratamiento de enfermedades.Industria farmacéutica, particularmente, proteínas de uniones multiespecíficas y multivalentes con capacidad de unir dos o más antígenos, composiciones farmacéuticas que contienen dichas proteínas de unión y métodos para elaborar tales proteínas de unión.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25568609P | 2009-10-28 | 2009-10-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6551686A2 true CO6551686A2 (es) | 2012-10-31 |
Family
ID=43989725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO12081792A CO6551686A2 (es) | 2009-10-28 | 2012-05-17 | Inmunoglobinas con dominio variable dual y usos de las mismas |
Country Status (22)
Country | Link |
---|---|
US (2) | US8722855B2 (es) |
EP (1) | EP2493924A4 (es) |
JP (1) | JP2013509189A (es) |
KR (1) | KR20140015145A (es) |
CN (1) | CN102770451A (es) |
AR (1) | AR078795A1 (es) |
AU (1) | AU2010319850B2 (es) |
BR (1) | BR112012010241A2 (es) |
CA (1) | CA2778140A1 (es) |
CL (1) | CL2012001037A1 (es) |
CO (1) | CO6551686A2 (es) |
CR (1) | CR20120266A (es) |
EC (1) | ECSP12011922A (es) |
GT (1) | GT201200125A (es) |
IL (1) | IL219474A0 (es) |
MX (1) | MX2012005037A (es) |
NZ (3) | NZ707465A (es) |
PE (1) | PE20121543A1 (es) |
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TW201124534A (en) | 2011-07-16 |
JP2013509189A (ja) | 2013-03-14 |
KR20140015145A (ko) | 2014-02-06 |
WO2011059755A2 (en) | 2011-05-19 |
US20140308286A1 (en) | 2014-10-16 |
NZ600100A (en) | 2014-03-28 |
GT201200125A (es) | 2013-09-30 |
MX2012005037A (es) | 2012-05-22 |
US20110212094A1 (en) | 2011-09-01 |
RU2012121813A (ru) | 2013-12-10 |
EP2493924A2 (en) | 2012-09-05 |
NZ707465A (en) | 2015-08-28 |
AU2010319850B2 (en) | 2013-10-10 |
PE20121543A1 (es) | 2012-12-22 |
AR078795A1 (es) | 2011-12-07 |
CA2778140A1 (en) | 2011-05-19 |
US8722855B2 (en) | 2014-05-13 |
AU2010319850A1 (en) | 2012-06-14 |
EP2493924A4 (en) | 2013-05-29 |
BR112012010241A2 (pt) | 2016-12-06 |
UY32979A (es) | 2011-02-28 |
CL2012001037A1 (es) | 2012-09-14 |
WO2011059755A3 (en) | 2011-07-28 |
ECSP12011922A (es) | 2012-07-31 |
CR20120266A (es) | 2012-08-14 |
CN102770451A (zh) | 2012-11-07 |
NZ620267A (en) | 2015-06-26 |
IL219474A0 (en) | 2012-06-28 |
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