CO4970829A1 - Polimorfo antifungico cristalino - Google Patents
Polimorfo antifungico cristalinoInfo
- Publication number
- CO4970829A1 CO4970829A1 CO98057733A CO98057733A CO4970829A1 CO 4970829 A1 CO4970829 A1 CO 4970829A1 CO 98057733 A CO98057733 A CO 98057733A CO 98057733 A CO98057733 A CO 98057733A CO 4970829 A1 CO4970829 A1 CO 4970829A1
- Authority
- CO
- Colombia
- Prior art keywords
- antifungal
- crystalline polymorph
- polymorph
- triazol
- phenyl
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- -1 1H- 1,2,4-triazol-1-ylmethyl Chemical group 0.000 abstract 1
- 125000004215 2,4-difluorophenyl group Chemical group [H]C1=C([H])C(*)=C(F)C([H])=C1F 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- STTHYLJITRSSSN-JQWIXIFHSA-N C1(=CC=CC=C1)N1C(N(N=C1)[C@H]([C@H](C)O)CC)=O Chemical compound C1(=CC=CC=C1)N1C(N(N=C1)[C@H]([C@H](C)O)CC)=O STTHYLJITRSSSN-JQWIXIFHSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94618397A | 1997-10-07 | 1997-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4970829A1 true CO4970829A1 (es) | 2000-11-07 |
Family
ID=25484068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO98057733A CO4970829A1 (es) | 1997-10-07 | 1998-10-05 | Polimorfo antifungico cristalino |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1021439B1 (OSRAM) |
| JP (4) | JP2001519346A (OSRAM) |
| KR (1) | KR100626109B1 (OSRAM) |
| CN (1) | CN1125067C (OSRAM) |
| AR (1) | AR015947A1 (OSRAM) |
| AT (1) | ATE263163T1 (OSRAM) |
| AU (1) | AU759982B2 (OSRAM) |
| BR (1) | BR9812866A (OSRAM) |
| CA (1) | CA2305803C (OSRAM) |
| CO (1) | CO4970829A1 (OSRAM) |
| CZ (1) | CZ299835B6 (OSRAM) |
| DE (1) | DE69822859T2 (OSRAM) |
| DK (1) | DK1021439T3 (OSRAM) |
| ES (1) | ES2217594T3 (OSRAM) |
| HU (1) | HU225233B1 (OSRAM) |
| ID (1) | ID29290A (OSRAM) |
| IL (1) | IL135331A (OSRAM) |
| IN (1) | IN1998CH02232A (OSRAM) |
| MX (1) | MX225999B (OSRAM) |
| MY (1) | MY130126A (OSRAM) |
| NO (1) | NO318827B1 (OSRAM) |
| NZ (1) | NZ503662A (OSRAM) |
| PE (1) | PE120499A1 (OSRAM) |
| PH (1) | PH11998002606B1 (OSRAM) |
| PL (1) | PL189317B1 (OSRAM) |
| PT (1) | PT1021439E (OSRAM) |
| SK (1) | SK285190B6 (OSRAM) |
| TW (1) | TW589310B (OSRAM) |
| WO (1) | WO1999018097A1 (OSRAM) |
| ZA (1) | ZA989063B (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| CA2767489A1 (en) | 2009-07-09 | 2011-01-13 | Sandoz Ag | A crystalline form of posaconazole |
| WO2011144656A1 (en) | 2010-05-19 | 2011-11-24 | Sandoz Ag | Preparation of posaconazole intermediates |
| MX2012013331A (es) | 2010-05-19 | 2013-02-01 | Sandoz Ag | Purificacion de posaconazol y de intermediarios de posaconazol. |
| CN102892750B (zh) | 2010-05-19 | 2016-03-02 | 桑多斯股份公司 | 制备手性酰肼的方法 |
| AU2011254654B2 (en) * | 2010-05-19 | 2016-01-07 | Sandoz Ag | Process for the preparation of chiral triazolones |
| CN108329303A (zh) | 2011-06-16 | 2018-07-27 | 桑多斯股份公司 | 制备手性化合物的方法 |
| WO2013042138A2 (en) | 2011-09-19 | 2013-03-28 | Msn Laboratories Limited | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof |
| EP3024828B1 (en) * | 2013-07-25 | 2017-05-17 | Sandoz AG | Improved process for the preparation of crystalline form iv of posaconazole |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132114A1 (it) | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| CN111825717A (zh) | 2014-10-21 | 2020-10-27 | 阿瑞雅德制药公司 | 5-氯-n4-[2-(二甲基磷酰基)苯基]-n2-{2-甲氧基-4-[4-(4-甲基哌嗪-1-基)哌啶-1-基]苯基}嘧啶-2,4-二胺的晶形 |
| CN104387374A (zh) * | 2014-10-21 | 2015-03-04 | 江苏恒盛药业有限公司 | 泊沙康唑晶型i的制备工艺 |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| PL3331501T3 (pl) | 2015-08-08 | 2020-03-31 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Preparat o zwiększonej odporności na warunki przewodu pokarmowego zawierający pozakonazol |
| HK1256362A1 (zh) | 2015-12-24 | 2019-09-20 | Takeda Pharmaceutical Company Limited | 共晶、其制造方法及含有共晶的药物 |
| EP3210599B1 (en) | 2016-02-26 | 2024-08-28 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| CN105949278B (zh) * | 2016-03-30 | 2019-12-06 | 南京曼杰生物科技有限公司 | 一种取代的四氢呋喃水溶性衍生物及其应用 |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| TR201722493A2 (tr) | 2017-12-28 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Posakonazol i̇çeren kati farmasöti̇k kompozi̇syon |
| WO2022034232A1 (en) | 2020-08-13 | 2022-02-17 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| AU2022324717A1 (en) | 2021-11-25 | 2024-06-13 | Alfred E. Tiefenbacher (Gmbh Und Co. Kg) | Granules containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| DE122006000004I2 (de) * | 1993-12-21 | 2007-03-29 | Schering Corp | Fungizide Tetrahydrofurane |
| SK282059B6 (sk) * | 1994-01-24 | 2001-10-08 | Janssen Pharmaceutica N. V. | Azoly, spôsob ich výroby a farmaceutické prostriedky na ich báze |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| CN1073109C (zh) * | 1995-06-02 | 2001-10-17 | 先灵公司 | 四氢呋喃杀真菌剂 |
-
1998
- 1998-10-05 PT PT98951994T patent/PT1021439E/pt unknown
- 1998-10-05 DK DK98951994T patent/DK1021439T3/da active
- 1998-10-05 ZA ZA989063A patent/ZA989063B/xx unknown
- 1998-10-05 HU HU0004899A patent/HU225233B1/hu unknown
- 1998-10-05 AR ARP980104957A patent/AR015947A1/es not_active Application Discontinuation
- 1998-10-05 EP EP98951994A patent/EP1021439B1/en not_active Expired - Lifetime
- 1998-10-05 CN CN98811886A patent/CN1125067C/zh not_active Expired - Lifetime
- 1998-10-05 IL IL13533198A patent/IL135331A/xx not_active IP Right Cessation
- 1998-10-05 AT AT98951994T patent/ATE263163T1/de active
- 1998-10-05 ES ES98951994T patent/ES2217594T3/es not_active Expired - Lifetime
- 1998-10-05 NZ NZ503662A patent/NZ503662A/xx not_active IP Right Cessation
- 1998-10-05 CA CA002305803A patent/CA2305803C/en not_active Expired - Lifetime
- 1998-10-05 DE DE69822859T patent/DE69822859T2/de not_active Expired - Lifetime
- 1998-10-05 KR KR20007003709A patent/KR100626109B1/ko not_active Expired - Lifetime
- 1998-10-05 PL PL98339659A patent/PL189317B1/pl unknown
- 1998-10-05 BR BR9812866-3A patent/BR9812866A/pt not_active Application Discontinuation
- 1998-10-05 AU AU97803/98A patent/AU759982B2/en not_active Expired
- 1998-10-05 JP JP2000514908A patent/JP2001519346A/ja not_active Withdrawn
- 1998-10-05 CO CO98057733A patent/CO4970829A1/es unknown
- 1998-10-05 ID IDW20000632A patent/ID29290A/id unknown
- 1998-10-05 WO PCT/US1998/020476 patent/WO1999018097A1/en not_active Ceased
- 1998-10-05 SK SK512-2000A patent/SK285190B6/sk not_active IP Right Cessation
- 1998-10-05 CZ CZ20001264A patent/CZ299835B6/cs not_active IP Right Cessation
- 1998-10-05 PE PE1998000942A patent/PE120499A1/es not_active IP Right Cessation
- 1998-10-06 MY MYPI98004576A patent/MY130126A/en unknown
- 1998-10-06 TW TW087116562A patent/TW589310B/zh not_active IP Right Cessation
- 1998-10-06 PH PH11998002606A patent/PH11998002606B1/en unknown
- 1998-10-06 IN IN2232CH1998 patent/IN1998CH02232A/en unknown
-
2000
- 2000-04-06 NO NO20001779A patent/NO318827B1/no not_active IP Right Cessation
- 2000-04-06 MX MXPA00003404 patent/MX225999B/es active IP Right Grant
-
2008
- 2008-01-04 JP JP2008000110A patent/JP2008106075A/ja not_active Withdrawn
-
2012
- 2012-05-18 JP JP2012114725A patent/JP2012153730A/ja active Pending
- 2012-05-18 JP JP2012114724A patent/JP2012153729A/ja active Pending
Also Published As
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