CN110831933A

CN110831933A - 喹唑啉衍生物作为突变kras、hras或nras的调节剂

喹唑啉衍生物作为突变kras、hras或nras的调节剂 Download PDF

Info

Publication number: CN110831933A
Authority: CN; China
Prior art keywords: compound; cancer; alkyl; group; compounds
Prior art date: 2017-05-25
Legal status : Pending

Application number

CN201880034310.1A

Other languages

English (en)

Chinese (zh)

Inventor

李连升

冯军

吴涛

刘源

王祎

任平达

刘毅

Current Assignee

Araxes Pharma LLC

Original Assignee

Araxes Pharma LLC

Priority date

2017-05-25

Filing date

2018-05-24

Publication date

2020-02-21

2018-05-24 Application filed by Araxes Pharma LLC filed Critical Araxes Pharma LLC

2020-02-21 Publication of CN110831933A publication Critical patent/CN110831933A/zh

Status Pending legal-status Critical Current

Links

102100030708 GTPase KRas Human genes 0.000 title claims abstract description 69
101000584612 Homo sapiens GTPase KRas Proteins 0.000 title claims abstract description 69
102100029974 GTPase HRas Human genes 0.000 title claims description 76
101000584633 Homo sapiens GTPase HRas Proteins 0.000 title claims description 75
102100039788 GTPase NRas Human genes 0.000 title description 42
101000744505 Homo sapiens GTPase NRas Proteins 0.000 title description 42
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125000000623 heterocyclic group Chemical group 0.000 claims description 78
125000000217 alkyl group Chemical group 0.000 claims description 76
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