AU2002352444A1 - Quinazolinedione derivatives - Google Patents

Quinazolinedione derivatives

Info

Publication number
AU2002352444A1
AU2002352444A1 AU2002352444A AU2002352444A AU2002352444A1 AU 2002352444 A1 AU2002352444 A1 AU 2002352444A1 AU 2002352444 A AU2002352444 A AU 2002352444A AU 2002352444 A AU2002352444 A AU 2002352444A AU 2002352444 A1 AU2002352444 A1 AU 2002352444A1
Authority
AU
Australia
Prior art keywords
quinazolinedione derivatives
quinazolinedione
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002352444A
Inventor
Hazel Joan Dyke
Alan Findlay Haughan
Marianna Dilani Richard
Andrew Sharpe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0130585A external-priority patent/GB0130585D0/en
Priority claimed from GB0204137A external-priority patent/GB0204137D0/en
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of AU2002352444A1 publication Critical patent/AU2002352444A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002352444A 2001-12-20 2002-12-18 Quinazolinedione derivatives Abandoned AU2002352444A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0130585.3 2001-12-20
GB0130585A GB0130585D0 (en) 2001-12-20 2001-12-20 Chemical compounds
GB0204137.4 2002-02-22
GB0204137A GB0204137D0 (en) 2002-02-22 2002-02-22 Chemical compounds
PCT/GB2002/005770 WO2003053958A1 (en) 2001-12-20 2002-12-18 Quinazolinedione derivatives

Publications (1)

Publication Number Publication Date
AU2002352444A1 true AU2002352444A1 (en) 2003-07-09

Family

ID=26246893

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002352444A Abandoned AU2002352444A1 (en) 2001-12-20 2002-12-18 Quinazolinedione derivatives

Country Status (2)

Country Link
AU (1) AU2002352444A1 (en)
WO (1) WO2003053958A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516548A (en) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト Drug delivery from rapidly gelled polymer compositions
BRPI0706610A2 (en) * 2006-01-18 2011-04-05 Siena Biotech Spa nicotinically acetylcholine alpha 7 receptor modulators and therapeutic uses of these
EP2001875A2 (en) * 2006-03-08 2008-12-17 Takeda San Diego, Inc. Glucokinase activators
JP5675341B2 (en) * 2007-04-18 2015-02-25 プロビオドルグ エージー Thioxoquinazolinone derivatives as glutaminyl cyclase inhibitors
WO2012058211A2 (en) * 2010-10-29 2012-05-03 Emory University Quinazoline derivatives, compositions, and uses related thereto
SG11201406860SA (en) * 2012-04-24 2014-11-27 Chugai Pharmaceutical Co Ltd Quinazolinedione derivative
BR112014026266A2 (en) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd quinazolidinedione derivative
US9227978B2 (en) 2013-03-15 2016-01-05 Araxes Pharma Llc Covalent inhibitors of Kras G12C
US10253027B2 (en) 2013-07-08 2019-04-09 Bristol-Myers Squibb Company Aryl lactam kinase inhibitors
TWI659021B (en) 2013-10-10 2019-05-11 亞瑞克西斯製藥公司 Inhibitors of kras g12c
CA2927830A1 (en) 2013-10-23 2015-04-30 Chugai Seiyaku Kabushiki Kaisha Quinazolinone and isoquinolinone derivative
GB201410407D0 (en) * 2014-06-11 2014-07-23 Univ Dundee And Syngene Internat Ltd Plc And Consejo Superior De Investigaciones Cientificas And Med Treatment of chagas disease
MX2018000777A (en) * 2015-07-22 2018-03-23 Araxes Pharma Llc Substituted quinazoline compounds and their use as inhibitors of g12c mutant kras, hras and/or nras proteins.
US10975071B2 (en) 2015-09-28 2021-04-13 Araxes Pharma Llc Inhibitors of KRAS G12C mutant proteins
JP7015059B2 (en) 2015-11-16 2022-02-15 アラクセス ファーマ エルエルシー 2-substituted quinazoline compounds containing substituted heterocyclic groups and their usage
US11274093B2 (en) 2017-01-26 2022-03-15 Araxes Pharma Llc Fused bicyclic benzoheteroaromatic compounds and methods of use thereof
EP3573967A1 (en) 2017-01-26 2019-12-04 Araxes Pharma LLC Fused hetero-hetero bicyclic compounds and methods of use thereof
EP3573971A1 (en) 2017-01-26 2019-12-04 Araxes Pharma LLC 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer
US11358959B2 (en) 2017-01-26 2022-06-14 Araxes Pharma Llc Benzothiophene and benzothiazole compounds and methods of use thereof
EP3573970A1 (en) 2017-01-26 2019-12-04 Araxes Pharma LLC 1-(6-(3-hydroxynaphthalen-1-yl)quinazolin-2-yl)azetidin-1-yl)prop-2-en-1-one derivatives and similar compounds as kras g12c inhibitors for the treatment of cancer
WO2018218069A1 (en) 2017-05-25 2018-11-29 Araxes Pharma Llc Quinazoline derivatives as modulators of mutant kras, hras or nras
JP2020521742A (en) 2017-05-25 2020-07-27 アラクセス ファーマ エルエルシー Covalent inhibitor of KRAS
CN113354592B (en) * 2021-06-30 2022-06-21 赣南师范大学 2-thioquinazolinone compound and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603095D0 (en) * 1996-02-14 1996-04-10 Zeneca Ltd Quinazoline derivatives

Also Published As

Publication number Publication date
WO2003053958A1 (en) 2003-07-03

Similar Documents

Publication Publication Date Title
AU2002221047A1 (en) Quinazolinone derivatives
AU2002349676A1 (en) 4-oxoquinoline derivatives
AUPR975601A0 (en) Quinazolinone derivatives
AU2002367186A1 (en) Urea derivatives
AU2002352444A1 (en) Quinazolinedione derivatives
AU2002212436A1 (en) Quinazoline derivatives
AU2001292137A1 (en) Quinazoline derivatives
AU2002362806A1 (en) Pyrimidine derivatives
AU2002363600A1 (en) Novel phenyl-propargylether derivatives
AU2002338989A1 (en) Substituted C-furan-2-yl-methylamine and C-thiophen-2-yl-methylamine derivatives
AU2003263323A1 (en) Quinazolinone derivatives
AU2003255803A1 (en) Quinazolinone derivatives
AU2002358715A1 (en) Tetrahydrobenzfluorene derivatives
AU2001100406A4 (en) DriverSMS
AU2002233682A1 (en) Quinazoline derivatives
AU2002249413A1 (en) Quinazoline derivatives
AU2002256776A1 (en) Quinazoline derivatives
AU2002302736A1 (en) Quinazoline derivatives
AU2003290279A1 (en) Quinazoline derivatives
AU2002230181A1 (en) Novel quinazoline derivatives
AU2002255269B8 (en) 2-Iminopyrrolidine derivatives
AU2002323794A1 (en) Quinazolinone derivative
AU2002353537A1 (en) Quinazolinone derivative
AU2002311409A1 (en) Pyrimidine derivatives
AU2002255156A1 (en) 4-anilinoquinazoline derivatives

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase