CN108715602A - 基于crispr的基因组修饰和调控 - Google Patents

基于crispr的基因组修饰和调控 Download PDF

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Publication number
CN108715602A
CN108715602A CN201810540449.5A CN201810540449A CN108715602A CN 108715602 A CN108715602 A CN 108715602A CN 201810540449 A CN201810540449 A CN 201810540449A CN 108715602 A CN108715602 A CN 108715602A
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rna
sequence
endonuclease
nucleic acid
domain
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Chinese (zh)
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F.陈
G.D.戴维斯
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Sigma Aldrich Co LLC
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Sigma Aldrich Co LLC
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
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    • C12N2310/00—Structure or type of the nucleic acid
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CN201810540449.5A 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控 Pending CN108715602A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261734256P 2012-12-06 2012-12-06
US61/734256 2012-12-06
US201361758624P 2013-01-30 2013-01-30
US61/758624 2013-01-30
US201361761046P 2013-02-05 2013-02-05
US61/761046 2013-02-05
US201361794422P 2013-03-15 2013-03-15
US61/794422 2013-03-15
CN201380072477.4A CN105142669B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控

Related Parent Applications (1)

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CN201380072477.4A Division CN105142669B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控

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CN108715602A true CN108715602A (zh) 2018-10-30

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CN201810574719.4A Active CN108913676B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控
CN201380072477.4A Active CN105142669B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控
CN201810540449.5A Pending CN108715602A (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控

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CN201810574719.4A Active CN108913676B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控
CN201380072477.4A Active CN105142669B (zh) 2012-12-06 2013-12-05 基于crispr的基因组修饰和调控

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US (15) US20160017366A1 (enExample)
EP (11) EP3138911B1 (enExample)
JP (6) JP6620018B2 (enExample)
KR (7) KR102479178B1 (enExample)
CN (3) CN108913676B (enExample)
AU (9) AU2013355214B2 (enExample)
BR (1) BR112015012375A2 (enExample)
CA (3) CA2977152C (enExample)
DK (6) DK3363902T3 (enExample)
ES (6) ES2769310T3 (enExample)
IL (5) IL300199B2 (enExample)
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PT (6) PT3138910T (enExample)
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CN115243711A (zh) * 2020-01-09 2022-10-25 先锋国际良种公司 两步基因交换

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